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Your search keyword '"Lin, Zhihua"' showing total 34 results
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34 results on '"Lin, Zhihua"'

8. Tungsten Nanoparticles Accelerate Polysulfides Conversion: A Viable Route toward Stable Room‐Temperature Sodium–Sulfur Batteries

Author

Liu, Yuping, primary, Ma, Shuangying, additional, Rosebrock, Marina, additional, Rusch, Pascal, additional, Barnscheidt, Yvo, additional, Wu, Chuanqiang, additional, Nan, Pengfei, additional, Bettels, Frederik, additional, Lin, Zhihua, additional, Li, Taoran, additional, Ge, Binghui, additional, Bigall, Nadja C., additional, Pfnür, Herbert, additional, Ding, Fei, additional, Zhang, Chaofeng, additional, and Zhang, Lin, additional

Published
2022
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9. Wearable Biosupercapacitor: Harvesting and Storing Energy from Sweat

Author

Lv, Jian, primary, Yin, Lu, additional, Chen, Xiaohong, additional, Jeerapan, Itthipon, additional, Silva, Cristian A., additional, Li, Yang, additional, Le, Minh, additional, Lin, Zhihua, additional, Wang, Luwen, additional, Trifonov, Alexander, additional, Xu, Sheng, additional, Cosnier, Serge, additional, and Wang, Joseph, additional

Published
2021
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17. Structure‐Dependent Optical Modulation of Propulsion and Collective Behavior of Acoustic/Light‐Driven Hybrid Microbowls

Author

Tang, Songsong, primary, Zhang, Fangyu, additional, Zhao, Jing, additional, Talaat, Wael, additional, Soto, Fernando, additional, Karshalev, Emil, additional, Chen, Chuanrui, additional, Hu, Zhihan, additional, Lu, Xiaolong, additional, Li, Jinxing, additional, Lin, Zhihua, additional, Dong, Haifeng, additional, Zhang, Xueji, additional, Nourhani, Amir, additional, and Wang, Joseph, additional

Published
2019
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19. Research Article: Quantitative Sequence-Kinetics Relationship in Antigen-Antiboby Interaction Kinetics Based on a Set of Descriptors

Author

Wang Yuan-Qiang, Yang Ying, Cheng Xiaoming, Zhu Bo, Lin Zhihua, Lin Yong, Xie Rong-kai, and Long Haixia

Subjects
Pharmacology, chemistry.chemical_classification, Quantitative structure–activity relationship, Chemistry, Stereochemistry, Organic Chemistry, Kinetics, Biochemistry, Peptide antigen, Amino acid, law.invention, Antigen-antibody interaction, law, Drug Discovery, Recombinant DNA, Tobacco mosaic virus, Molecular Medicine, Peptide sequence
Abstract

The interaction between recombinant Fab57P and the coat protein of tobacco mosaic virus was studied using quantitative structure–activity relationship (QSAR) method. The development of quantitative multivariate model has shown to be a promising approach for unraveling protein–protein interactions by designed mutations in peptide sequence. This approach makes it possible to stereo-chemically determine which residue properties contribute most to the interaction. A set of side-chain descriptors was proposed and applied in structural characterization of three positions (positions 142, 145 and 146) in the peptide antigen. Quantitative sequence–kinetics relationship (QSKR) models describing the dissociation rates (log kd) were developed successfully using orthogonal signal correction–partial least squares method. The results showed that peptides will have high log kd values when the amino acids in position 142 and 145 have high net charge index, and when residue 145 has high hydrophobicity and residue 146 has low hydrophobicity.

Published
2010
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23. Pigments accumulation via light and oxygen in Rhodobacter capsulatus strain XJ-1 isolated from saline soil

Author

Lin, Zhihua, Cui, Xiaohua, Zhao, Chungui, Yang, Suping, Imhoff, Johannes F., Lin, Zhihua, Cui, Xiaohua, Zhao, Chungui, Yang, Suping, and Imhoff, Johannes F.

Abstract

A Rhodobacter capsulatus strain, designated XJ-1, isolated from saline soil, accumulated almost only one kind of bacteriochlorophyll a anaerobically in the light, aerobically in the light and dark, and the relative contents of the bacteriochlorophyll a were 44.61, 74.89, and 77.53% of the total pigments, respectively. A new purple pigment appeared only in aerobic-light grown cells, exhibited absorption maxima at 355, 389, 520, 621, and 755 nm, especially distinctly unusual peak at 621 nm, whereas vanished in anaerobic-light and in aerobic-dark culture. Spheroidene and OH–spheroidene predominated in anaerobic phototrophic cultures. Spheroidenone was the sole carotenoid when exposed to both light and oxygen. The second keto-carotenoids, OH–spheroidenone, presented only in aerobic-dark culture in addition to spheroidenone. Strain XJ-1 would be a good model organism for the further illustration of the regulation of bacteriochlorophyll biosynthesis gene expression in response to unique habitat.

Published
2014
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34. Oxybutynin ameliorates LPS-induced inflammatory response in human bladder epithelial cells.

Author

Chen C, Li J, Wang J, Zhang M, Zhang L, and Lin Z

Subjects
Humans, Cytokines metabolism, NF-kappa B metabolism, Inflammation chemically induced, Inflammation drug therapy, Nitric Oxide Synthase Type II metabolism, Epithelial Cells metabolism, Lipopolysaccharides toxicity, Urinary Bladder metabolism, Mandelic Acids
Abstract

Urinary tract infection (UTI) mainly results from bacterial infections in the urinary tract and markedly impacts the normal lives of millions of patients worldwide. The infection and damage to urethral epithelial cells is the first and key step of UTI development and is a critical target for treating clinical UTI. Oxybutynin, an agent for treating urinary incontinence, is recently claimed with protective effects on bladder ultrastructure. Our study will assess the impact of Oxybutynin on inflammation in lipopolysaccharide (LPS)-stimulated bladder epithelial cells. Bladder epithelial T24 cells were treated with 1 μg/mL LPS with or without 10 and 20 μM Oxybutynin for 24 h. Increased levels of oxidative stress (OS) biomarkers, such as reactive oxygen species, 8-hydroxy-2'-deoxyguanosine, malondialdehyde, as well as upregulated inducible nitric oxide synthase and promoted release of nitric oxide, were observed in LPS-managed T24 cells, all of which were signally suppressed by Oxybutynin. Furthermore, severe inflammatory responses, including enhanced release of cytokines, upregulated matrix metallopeptidase-2 (MMP-2) and MMP-9, and raised monocyte chemoattractant protein-1 level, were found in LPS-challenged T24 cells, which were markedly reversed by Oxybutynin. Moreover, the activated toll-1ike receptor 4/nuclear factor-κB pathway observed in LPS-managed T24 cells was repressed by Oxybutynin. Collectively, Oxybutynin mitigated LPS-induced inflammatory response in human bladder epithelial cells., (© 2023 Wiley Periodicals LLC.)

Published
2024
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