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Your search keyword '"Linné, T."' showing total 13 results
Start Over Author "Linné, T." Publisher wiley
13 results on '"Linné, T."'

13. Objective responses after fractionated infusional brachytherapy of unresectable pancreatic adenocarcinomas.

Author

Westlin JE, Andersson-Forsman C, Garske U, Linné T, Aas M, Glimelius B, Lindgren PG, Order SE, and Nilsson S

Subjects
Adult, Aged, Chromium Compounds therapeutic use, Colloids, Female, Humans, Male, Middle Aged, Phosphates therapeutic use, Adenocarcinoma radiotherapy, Brachytherapy adverse effects, Pancreatic Neoplasms radiotherapy
Abstract

Background: The prognosis of unresectable pancreatic adenocarcinoma is poor. Therefore, the treatment potential of an intratumoral infusional brachytherapy using macroaggregated human albumin in combination with radioactive chromic phosphate [32P] was investigated in this group of patients., Methods: Seventeen patients with unresectable tumors received intratumoral infusional brachytherapy. Treatment and assessment of response was performed with the aid of ultrasonography., Results: Four patients had complete response with a duration ranging from 2-57 weeks and 5 patients had partial response with a duration ranging from 4-21 weeks, corresponding to an objective response of 53% (9 of 17 patients). Six of these patients were alive 33-57 weeks after treatment. Radiation necrosis was observed in 1 patient after a 19,000-gray cumulative radiation dose and a slight decrease in blood counts was observed in 2 patients., Conclusions: Intratumoral infusional brachytherapy using radioactive colloidal chromic phosphate has the potential to reduce inoperable pancreatic tumors with few side effects.

Published
1997
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