1. The connection of alpha‐1 acid glycoprotein inflammatory marker with anthropometric, hormonal, and metabolic characteristic of women with polycystic ovary syndrome
- Author
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Ana Karine Lin Winck Yamamoto, Bruna Barcelo Barbosa, Sebastião Freitas de Medeiros, Matheus Antônio Souto de Medeiros, and Márcia Marly Winck Yamamoto
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,Orosomucoid ,Body adiposity index ,Body Mass Index ,Internal medicine ,medicine ,Humans ,Insulin ,Testosterone ,Anthropometry ,biology ,medicine.diagnostic_test ,business.industry ,Obstetrics and Gynecology ,Polycystic ovary ,Cross-Sectional Studies ,Endocrinology ,Erythrocyte sedimentation rate ,biology.protein ,Homeostatic model assessment ,Female ,Insulin Resistance ,business ,Body mass index ,Biomarkers ,Polycystic Ovary Syndrome ,Hormone - Abstract
AIM To investigate the connection of alpha-1 acid glycoprotein inflammatory biomarker with clinical, hormonal, and metabolic characteristics in women with polycystic ovary syndrome (PCOS) and normal cycling controls. METHODS A cross-sectional study was conducted on 235 women with PCOS and 92 normal cycling controls attended between 2008 and 2018. Alpha-1 acid glycoprotein levels were correlated with clinical, anthropometric, anthropometric-metabolic indexes, and hormones of women with PCOS and controls. Simple and multivariate stepwise linear regression, matched for age and body mass index confounding variables, was performed. RESULTS Alpha-1 acid glycoprotein levels were higher in women with PCOS (p = 0.0016). In controls, it was positively correlated with waist circumference, fat mass, body adiposity index, and lipid accumulation product, and negatively correlated with sex hormone-binding globulin (p
- Published
- 2021