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32 results on '"Müller, Bernhard"'

1. Amygdalar nuclei and hippocampal subfields on MRI: Test‐retest reliability of automated segmentation in old and young healthy volunteers

Author

Quattrini, Giulia, primary, Pievani, Michela, additional, Jovicich, Jorge, additional, Aiello, Marco, additional, Bargalló, Nuria, additional, Barkhof, Frederik, additional, Bartrés‐Faz, David, additional, Beltramello, Alberto, additional, Pizzini, Francesca B, additional, Blin, Olivier, additional, Bordet, Régis, additional, Caulo, Massimo, additional, Constantinides, Manos, additional, Didic, Mira, additional, Drevelegas, Antonios, additional, Ferretti, Antonio, additional, Fiedler, Ute, additional, Floridi, Piero, additional, Gros‐Dagnac, Helene, additional, Hensch, Tilman, additional, Hoffmann, Karl‐Titus, additional, Kuijer, Joost, additional, Lopes, Renaud, additional, Marra, Camillo, additional, Müller, Bernhard W., additional, Nobili, Flavio, additional, Parnetti, Lucilla, additional, Payoux, Pierre, additional, Picco, Agnese, additional, Ranjeva, Jean‐Philippe, additional, Roccatagliata, Luca, additional, Rossini, Paolo Maria, additional, Salvatore, Marco, additional, Schonknecht, Peter, additional, Schott, Björn H, additional, Sein, Julien, additional, Soricelli, Andrea, additional, Tarducci, Roberto, additional, Tsolaki, Magda, additional, Visser, Pieter Jelle, additional, Wiltfang, Jens, additional, Richardson, Jill, additional, Frisoni, Giovanni B, additional, Marizzoni, Moira, additional, and Consortium, PharmaCog, additional

Published
2020
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2. High-order ghost-point immersed boundary method for viscous compressible flows based on summation-by-parts operators

Author

Khalili, Mohammadtaghi, Larsson, Martin, and Müller, Bernhard

Subjects
Physics::Fluid Dynamics
Abstract

A high‐order immersed boundary method is devised for the compressible Navier‐Stokes equations by employing high‐order summation‐by‐parts difference operators. The immersed boundaries are treated as sharp interfaces by enforcing the solid wall boundary conditions via flow variables at ghost points. Two different interpolation schemes are tested to compute values at the ghost points and a hybrid treatment is used. The first method provides the bilinearly interpolated flow variables at the image points of the corresponding ghost points and the second method applies the boundary condition at the immersed boundary by using the weighted least squares method with high‐order polynomials. The approach is verified and validated for compressible flow past a circular cylinder at moderate Reynolds numbers. The tonal sound generated by vortex shedding from a circular cylinder is also investigated. In order to demonstrate the capability of the solver to handle complex geometries in practical cases, flow in a cross‐section of a human upper airway is simulated. This is the peer reviewed version of an article, which has been published in final form at [https://doi.org/10.1002/fld.4696]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving

Published
2019

3. A versatile optode system for oxygen, carbon dioxide, and pH measurements in seawater with integrated battery and logger

Author

Staudinger, Christoph, primary, Strobl, Martin, additional, Fischer, Jan P., additional, Thar, Roland, additional, Mayr, Torsten, additional, Aigner, Daniel, additional, Müller, Bernhard J., additional, Müller, Bernhard, additional, Lehner, Philipp, additional, Mistlberger, Günter, additional, Fritzsche, Eva, additional, Ehgartner, Josef, additional, Zach, Peter W., additional, Clarke, Jennifer S., additional, Geißler, Felix, additional, Mutzberg, André, additional, Müller, Jens D., additional, Achterberg, Eric P., additional, Borisov, Sergey M., additional, and Klimant, Ingo, additional

Published
2018
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6. IC‐P‐126: VOLUMETRIC ACCURACY OF A FULLY AUTOMATIC TOOL FOR WHITE MATTER HYPERINTENSITIES (WMHS) SEGMENTATION

Author

Ribaldi, Federica, primary, Jovicich, Jorge, additional, Ferrari, Clarissa, additional, Bosch, Beatriz, additional, Bartrés-Faz, David, additional, Müller, Bernhard W., additional, Wiltfang, Jens, additional, Fiedler, Ute, additional, Montalti, Martina, additional, Roccatagliata, Luca, additional, Picco, Agnese, additional, Nobili, Flavio, additional, Blin, Olivier, additional, Bombois, Stephanie, additional, Lopes, Renaud, additional, Bordet, Régis, additional, Sein, Julien, additional, Ranjeva, Jean-Philippe, additional, Didic, Mira, additional, Gros-Dagnac, Helene, additional, Payoux, Pierre, additional, Alessandrini, Franco, additional, Beltramello, Alberto, additional, Bargallo, Núria, additional, Ferretti, Antonio, additional, Caulo, Massimo, additional, Aiello, Marco, additional, Cavaliere, Carlo, additional, Soricelli, Andrea, additional, Parnetti, Lucilla, additional, Tarducci, Robertto, additional, Floridi, Piero, additional, Tsolaki, Magda, additional, Constantinides, Manos, additional, Drevelegas, Antonios, additional, Rossini, Paolo, additional, Marra, Camillo, additional, Schonknecht, Peter, additional, Hensch, Tilman, additional, Hoffmann, Karl-Titus, additional, Kuijer, Joost, additional, Visser, Pieter Jelle, additional, Barkhof, Frederik, additional, Frisoni, Giovanni B., additional, and Marizzoni, Moira, additional

Published
2018
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8. Nanoparticle‐Based Fluoroionophore for Analysis of Potassium Ion Dynamics in 3D Tissue Models and In Vivo

Author

Müller, Bernhard J., primary, Zhdanov, Alexander V., additional, Borisov, Sergey M., additional, Foley, Tara, additional, Okkelman, Irina A., additional, Tsytsarev, Vassiliy, additional, Tang, Qinggong, additional, Erzurumlu, Reha S., additional, Chen, Yu, additional, Zhang, Haijiang, additional, Toncelli, Claudio, additional, Klimant, Ingo, additional, Papkovsky, Dmitri B., additional, and Dmitriev, Ruslan I., additional

Published
2018
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9. [IC-P-167]: ACROSS-SESSION REPRODUCIBILITY OF AUTOMATIC WHITE MATTER HYPERINTENSITIES SEGMENTATION: A EUROPEAN MULTI-SITE 3T STUDY

Author

Ribaldi, Federica, primary, Marizzoni, Moira, additional, Jovicich, Jorge, additional, Ferrari, Clarissa, additional, Bosch, Beatriz, additional, Bartrés-Faz, David, additional, Müller, Bernhard W., additional, Wiltfang, Jens, additional, Fiedler, Ute, additional, Roccatagliata, Luca, additional, Picco, Agnese, additional, Nobili, Flavio, additional, Blin, Olivier, additional, Bombois, Stephanie, additional, Lopes, Renaud, additional, Bordet, Regis, additional, Sein, Julien, additional, Ranjeva, Jean-Philippe, additional, Didic, Mira, additional, Gros-Dagnac, Helene, additional, Payoux, Pierre, additional, Zoccatelli, Giada, additional, Alessandrini, Franco, additional, Beltramello, Alberto, additional, Bargalló, Nuria, additional, Ferretti, Antonio, additional, Caulo, Massimo, additional, Aiello, Marco, additional, Cavaliere, Carlo, additional, Soricelli, Andrea, additional, Parnetti, Lucilla, additional, Tarducci, Robertto, additional, Floridi, Piero, additional, Tsolaki, Magda, additional, Constantinides, Manos, additional, Drevelegas, Antonios, additional, Rossini, Paolo Maria, additional, Marra, Camillo, additional, Schonknecht, Peter, additional, Hensch, Tilman, additional, Hoffmann, Karl-Titus, additional, Kuijer, Joost, additional, Visser, Pieter Jelle, additional, Barkhof, Frederik, additional, and Frisoni, Giovanni B., additional

Published
2017
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10. ACROSS-SESSION REPRODUCIBILITY OF AUTOMATIC WHITE MATTER HYPERINTENSITIES SEGMENTATION: A EUROPEAN MULTI-SITE 3T STUDY

Author

Ribaldi, Federica, primary, Marizzoni, Moira, additional, Jovicich, Jorge, additional, Ferrari, Clarissa, additional, Bosch, Beatriz, additional, Bartrés-Faz, David, additional, Müller, Bernhard W., additional, Wiltfang, Jens, additional, Fiedler, Ute, additional, Roccatagliata, Luca, additional, Picco, Agnese, additional, Nobili, Flavio, additional, Blin, Olivier, additional, Bombois, Stephanie, additional, Lopes, Renaud, additional, Bordet, Regis, additional, Sein, Julien, additional, Ranjeva, Jean-Philippe, additional, Didic, Mira, additional, Gros-Dagnac, Helene, additional, Payoux, Pierre, additional, Zoccatelli, Giada, additional, Alessandrini, Franco, additional, Beltramello, Alberto, additional, Bargallo, Núria, additional, Ferretti, Antonio, additional, Caulo, Massimo, additional, Aiello, Marco, additional, Cavaliere, Carlo, additional, Soricelli, Andrea, additional, Parnetti, Lucilla, additional, Tarducci, Robertto, additional, Floridi, Piero, additional, Tsolaki, Magda, additional, Constantinides, Manos, additional, Drevelegas, Antonios, additional, Rossini, Paolo Maria, additional, Marra, Camillo, additional, Schonknecht, Peter, additional, Hensch, Tilman, additional, Hoffmann, Karl-Titus, additional, Kuijer, Joost, additional, Visser, Pieter Jelle, additional, Barkhof, Frederik, additional, and Frisoni, Giovanni B., additional

Published
2017
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11. Negative schemata about the self and others and paranoid ideation in at-risk states and those with persisting positive symptoms

Author

Müller, Hendrik, primary, de Millas, Walter, additional, Gaebel, Wolfgang, additional, Herrlich, Jutta, additional, Hasan, Alkomiet, additional, Janssen, Birgit, additional, Juckel, Georg, additional, Karow, Anne, additional, Kircher, Tilo, additional, Kiszkenow-Bäker, Stefanie, additional, Klingberg, Stefan, additional, Klosterkötter, Joachim, additional, Krüger-Özgürdal, Seza, additional, Lambert, Martin, additional, Lautenschlager, Marion, additional, Maier, Wolfgang, additional, Michel, Tanja Maria, additional, Mehl, Stefanie, additional, Müller, Bernhard W., additional, Pützfeld, Verena, additional, Rausch, Franziska, additional, Riedel, Michael, additional, Sartory, Gudrun, additional, Schneider, Frank, additional, Wagner, Michael, additional, Wiedemann, Georg, additional, Wittorf, Andreas, additional, Wobrock, Thomas, additional, Wölwer, Wolfgang, additional, Zink, Mathias, additional, and Bechdolf, Andreas, additional

Published
2017
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13. Test-retest reliability of the default mode network in a multi-centric fMRI study of healthy elderly: Effects of data-driven physiological noise correction techniques

Author

Marchitelli, Rocco, primary, Minati, Ludovico, additional, Marizzoni, Moira, additional, Bosch, Beatriz, additional, Bartrés-Faz, David, additional, Müller, Bernhard W., additional, Wiltfang, Jens, additional, Fiedler, Ute, additional, Roccatagliata, Luca, additional, Picco, Agnese, additional, Nobili, Flavio, additional, Blin, Oliver, additional, Bombois, Stephanie, additional, Lopes, Renaud, additional, Bordet, Régis, additional, Sein, Julien, additional, Ranjeva, Jean-Philippe, additional, Didic, Mira, additional, Gros-Dagnac, Hélène, additional, Payoux, Pierre, additional, Zoccatelli, Giada, additional, Alessandrini, Franco, additional, Beltramello, Alberto, additional, Bargalló, Núria, additional, Ferretti, Antonio, additional, Caulo, Massimo, additional, Aiello, Marco, additional, Cavaliere, Carlo, additional, Soricelli, Andrea, additional, Parnetti, Lucilla, additional, Tarducci, Roberto, additional, Floridi, Piero, additional, Tsolaki, Magda, additional, Constantinidis, Manos, additional, Drevelegas, Antonios, additional, Rossini, Paolo Maria, additional, Marra, Camillo, additional, Schönknecht, Peter, additional, Hensch, Tilman, additional, Hoffmann, Karl-Titus, additional, Kuijer, Joost P., additional, Visser, Pieter Jelle, additional, Barkhof, Frederik, additional, Frisoni, Giovanni B., additional, and Jovicich, Jorge, additional

Published
2016
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30. Free water elimination improves test-retest reproducibility of diffusion tensor imaging indices in the brain: A longitudinal multisite study of healthy elderly subjects.

Author

Albi A, Pasternak O, Minati L, Marizzoni M, Bartrés-Faz D, Bargalló N, Bosch B, Rossini PM, Marra C, Müller B, Fiedler U, Wiltfang J, Roccatagliata L, Picco A, Nobili FM, Blin O, Sein J, Ranjeva JP, Didic M, Bombois S, Lopes R, Bordet R, Gros-Dagnac H, Payoux P, Zoccatelli G, Alessandrini F, Beltramello A, Ferretti A, Caulo M, Aiello M, Cavaliere C, Soricelli A, Parnetti L, Tarducci R, Floridi P, Tsolaki M, Constantinidis M, Drevelegas A, Frisoni G, and Jovicich J

Subjects
Aged, Aged, 80 and over, Anisotropy, Female, Healthy Volunteers, Humans, Imaging, Three-Dimensional, Longitudinal Studies, Male, Middle Aged, Reproducibility of Results, White Matter diagnostic imaging, Aging, Brain diagnostic imaging, Diffusion Tensor Imaging, Water metabolism
Abstract

Free water elimination (FWE) in brain diffusion MRI has been shown to improve tissue specificity in human white matter characterization both in health and in disease. Relative to the classical diffusion tensor imaging (DTI) model, FWE is also expected to increase sensitivity to microstructural changes in longitudinal studies. However, it is not clear if these two models differ in their test-retest reproducibility. This study compares a bi-tensor model for FWE with DTI by extending a previous longitudinal-reproducibility 3T multisite study (10 sites, 7 different scanner models) of 50 healthy elderly participants (55-80 years old) scanned in two sessions at least 1 week apart. We computed the reproducibility of commonly used DTI metrics (FA: fractional anisotropy, MD: mean diffusivity, RD: radial diffusivity, and AXD: axial diffusivity), derived either using a DTI model or a FWE model. The DTI metrics were evaluated over 48 white-matter regions of the JHU-ICBM-DTI-81 white-matter labels atlas, and reproducibility errors were assessed. We found that relative to the DTI model, FWE significantly reduced reproducibility errors in most areas tested. In particular, for the FA and MD metrics, there was an average reduction of approximately 1% in the reproducibility error. The reproducibility scores did not significantly differ across sites. This study shows that FWE improves sensitivity and is thus promising for clinical applications, with the potential to identify more subtle changes. The increased reproducibility allows for smaller sample size or shorter trials in studies evaluating biomarkers of disease progression or treatment effects. Hum Brain Mapp 38:12-26, 2017. © 2016 Wiley Periodicals, Inc., (© 2016 Wiley Periodicals, Inc.)

Published
2017
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31. Longitudinal reproducibility of automatically segmented hippocampal subfields: A multisite European 3T study on healthy elderly.

Author

Marizzoni M, Antelmi L, Bosch B, Bartrés-Faz D, Müller BW, Wiltfang J, Fiedler U, Roccatagliata L, Picco A, Nobili F, Blin O, Bombois S, Lopes R, Sein J, Ranjeva JP, Didic M, Gros-Dagnac H, Payoux P, Zoccatelli G, Alessandrini F, Beltramello A, Bargalló N, Ferretti A, Caulo M, Aiello M, Cavaliere C, Soricelli A, Salvadori N, Parnetti L, Tarducci R, Floridi P, Tsolaki M, Constantinidis M, Drevelegas A, Rossini PM, Marra C, Hoffmann KT, Hensch T, Schönknecht P, Kuijer JP, Visser PJ, Barkhof F, Bordet R, Frisoni GB, and Jovicich J

Subjects
Aged, Europe, Female, Humans, Longitudinal Studies, Male, Middle Aged, Organ Size, Reproducibility of Results, Software, Aging pathology, Hippocampus anatomy & histology, Image Processing, Computer-Assisted methods, Magnetic Resonance Imaging methods, Pattern Recognition, Automated methods
Abstract

Recently, there has been an increased interest in the use of automatically segmented subfields of the human hippocampal formation derived from magnetic resonance imaging (MRI). However, little is known about the test-retest reproducibility of such measures, particularly in the context of multisite studies. Here, we report the reproducibility of automated Freesurfer hippocampal subfields segmentations in 65 healthy elderly enrolled in a consortium of 13 3T MRI sites (five subjects per site). Participants were scanned in two sessions (test and retest) at least one week apart. Each session included two anatomical 3D T1 MRI acquisitions harmonized in the consortium. We evaluated the test-retest reproducibility of subfields segmentation (i) to assess the effects of averaging two within-session T1 images and (ii) to compare subfields with whole hippocampus volume and spatial reliability. We found that within-session averaging of two T1 images significantly improved the reproducibility of all hippocampal subfields but not that of the whole hippocampus. Volumetric and spatial reproducibility across MRI sites were very good for the whole hippocampus, CA2-3, CA4-dentate gyrus (DG), subiculum (reproducibility error∼2% and DICE > 0.90), good for CA1 and presubiculum (reproducibility error ∼ 5% and DICE ∼ 0.90), and poorer for fimbria and hippocampal fissure (reproducibility error ∼ 15% and DICE < 0.80). Spearman's correlations confirmed that test-retest reproducibility improved with volume size. Despite considerable differences of MRI scanner configurations, we found consistent hippocampal subfields volumes estimation. CA2-3, CA4-DG, and sub-CA1 (subiculum, presubiculum, and CA1 pooled together) gave test-retest reproducibility similar to the whole hippocampus. Our findings suggest that the larger hippocampal subfields volume may be reliable longitudinal markers in multisite studies., (© 2015 Wiley Periodicals, Inc.)

Published
2015
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32. Sparse imaging and continuous event-related fMRI in the visual domain: a systematic comparison.

Author

Nebel K, Stude P, Wiese H, Müller B, de Greiff A, Forsting M, Diener HC, and Keidel M

Subjects
Adult, Evoked Potentials physiology, Evoked Potentials, Visual physiology, Female, Humans, Male, Observer Variation, Photic Stimulation, Reaction Time physiology, Sensitivity and Specificity, Visual Cortex anatomy & histology, Visual Pathways anatomy & histology, Brain Mapping methods, Magnetic Resonance Imaging methods, Visual Cortex physiology, Visual Pathways physiology, Visual Perception physiology
Abstract

Continuous image acquisition as used in most functional magnetic resonance imaging (fMRI) designs may conflict with specific experimental settings due to attendant, noisy gradient switching. In sparse fMRI, single images are recorded with a delay that allows the registration of the predicted peak of an evoked hemodynamic response (HDR). The aim of this study was to assess validity and sensitivity of single-trial sparse imaging within the visual domain. Thirteen subjects were scanned twice. Either continuous or sparse image acquisition was applied while participants viewed single trains of flashlights. Sparse fMRI results were compared to continuous event-related fMRI results on single- and multisubject level regarding spatial extent, overlap, and intensity of activation. In continuously recorded data, the variability of the HDR peak latency was examined because this measure determined the timing of sparse image acquisition. In sparse fMRI, the sensitivity was analyzed considering different numbers of averaged trials. Sparse imaging detected the core activity revealed using continuous fMRI. The intensity of signal changes detected by continuous or sparse fMRI was comparable. The HDR peak latency was stable across sessions, but intersubject and regional variability might have affected the power of sparse fMRI. In sparse imaging, adding trials resulted in extension of activation and improvement in statistical power. The comparison with established continuous fMRI confirms the validity of sparse imaging. Conventional event-related data acquisition and analysis provided more comprehensive results. However, only sparse fMRI offers the opportunity to apply stimuli and record further biosignals free of scanner-related artifacts during intervals without image acquisition.

Published
2005
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