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15 results on '"Mii, Sumiyuki"'

2. Cover Image, Volume 118, Number 1, January 2017

Author

Tome, Yasunori, primary, Yano, Shuya, additional, Sugimoto, Naotoshi, additional, Mii, Sumiyuki, additional, Bouvet, Michael, additional, Tsuchiya, Hiroyuki, additional, Kanaya, Fuminori, additional, and Hoffman, Robert M., additional

Published
2016
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8. Imaging UVC-induced DNA damage response in models of minimal cancer

Author

Miwa, Shinji, primary, Yano, Shuya, additional, Hiroshima, Yukihiko, additional, Tome, Yasunori, additional, Uehara, Fuminari, additional, Mii, Sumiyuki, additional, Efimova, Elena V., additional, Kimura, Hiroaki, additional, Hayashi, Katsuhiro, additional, Tsuchiya, Hiroyuki, additional, and Hoffman, Robert M., additional

Published
2013
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9. Dynamic color-coded fluorescence imaging of the cell-cycle phase, mitosis, and apoptosis demonstrates how caffeine modulates cisplatinum efficacy

Author

Miwa, Shinji, primary, Yano, Shuya, additional, Tome, Yasunori, additional, Sugimoto, Naotoshi, additional, Hiroshima, Yukihiko, additional, Uehara, Fuminari, additional, Mii, Sumiyuki, additional, Kimura, Hiroaki, additional, Hayashi, Katsuhiro, additional, Efimova, Elena V., additional, Fujiwara, Toshiyoshi, additional, Tsuchiya, Hiroyuki, additional, and Hoffman, Robert M., additional

Published
2013
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15. A case of primary cutaneous peripheral T-cell lymphoma, not otherwise specified, with cytotoxic phenotype showing multiple ulcers on the entire body.

Author

Obara K, Mii S, and Amoh Y

Subjects
Humans, Male, Middle Aged, Lymphoma, T-Cell, Cutaneous metabolism, Lymphoma, T-Cell, Cutaneous pathology, Lymphoma, T-Cell, Peripheral metabolism, Lymphoma, T-Cell, Peripheral pathology, Skin Neoplasms metabolism, Skin Neoplasms pathology, Skin Ulcer metabolism, Skin Ulcer pathology
Abstract

Primary cutaneous peripheral T-cell lymphoma, not otherwise specified (pcPTCL-NOS), is a rare, aggressive, fatal type of cutaneous T-cell lymphoma. The clinical presentation of pcPTCL-NOS is characterized by generalized plaques, nodules or tumors but ulcers are uncommon. We report an atypical case of pcPTCL-NOS with cytotoxic protein expression, presenting as multiple ulcers on the entire body. A 48-year-old man first presented with pruritic papules on the trunk. The papules gradually increased in number and became ulcerated. We finally diagnosed pcPTCL-NOS because of diffuse dermal infiltration of medium- to large-sized pleomorphic CD4 positive lymphoid cells. Ulceration suggests infiltration of lymphoid cells expressing cytotoxic proteins, which can induce apoptosis in the epidermis and dermis. Our patient died of bacterial sepsis that invaded from the uncontrollable ulcers. A suspicion of pcPTCL-NOS is needed when encountering clinical pictures of refractory multiple ulcers and a biopsy should always be performed, because treatment delay may lead to a very poor prognosis., (© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Published
2019
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