28 results on '"Mills AM"'
Search Results
2. Validation of the Data Collection on Adverse Events of Anti‐HIV Drugs (D:A:D) chronic kidney disease risk score in HIV‐infected patients in the USA
- Author
-
Mills, AM, primary, Schulman, KL, additional, Fusco, JS, additional, Brunet, L, additional, Hsu, R, additional, Beyer, A, additional, Prajapati, G, additional, Mounzer, K, additional, and Fusco, GP, additional
- Published
- 2020
- Full Text
- View/download PDF
3. Emergency medicine physician workforce attrition differences by age and gender.
- Author
-
Gettel CJ, Courtney DM, Agrawal P, Madsen TE, Rothenberg C, Mills AM, Lall MD, Keim SM, Kraus CK, Ranney ML, and Venkatesh AK
- Subjects
- Aged, Humans, Male, United States, Female, Middle Aged, Adult, Child, Cross-Sectional Studies, Medicare, Workforce, Emergency Medicine, Physicians
- Abstract
Background: Emergency care workforce concerns have gained national prominence given recent data suggesting higher than previously estimated attrition. With little known regarding characteristics of physicians leaving the workforce, we sought to investigate the age and number of years since residency graduation at which male and female emergency physicians (EPs) exhibited workforce attrition., Methods: We performed a repeated cross-sectional analysis of EPs reimbursed by Medicare linked to date of birth and residency graduation date data from the American Board of Emergency Medicine for the years 2013-2020. Stratified by gender, our primary outcomes were the median age and number of years since residency graduation at the time of attrition, defined as the last year during the study time frame that an EP provided clinical services. We constructed a multivariate logistic regression model to examine the association between gender and EP workforce attrition., Results: A total of 25,839 (70.2%) male and 10,954 (29.8%) female EPs were included. During the study years, 5905 male EPs exhibited attrition at a median (interquartile range [IQR]) age of 56.4 (44.5-65.4) years, and 2463 female EPs exhibited attrition at a median (IQR) age of 44.0 (38.0-53.9) years. Female gender (adjusted odds ratio 2.30, 95% confidence interval 1.82-2.91) was significantly associated with attrition from the workforce. Male and female EPs had respective median (IQR) post-residency graduation times in the workforce of 17.5 (9.5-25.5) years and 10.5 (5.5-18.5) years among those who exhibited attrition and one in 13 males and one in 10 females exited clinical practice within 5 years of residency graduation., Conclusions: Female physicians exhibited attrition from the EM workforce at an age approximately 12 years younger than male physicians. These data identify widespread disparities regarding EM workforce attrition that are critical to address to ensure stability, longevity, and diversity in the EP workforce., (© 2023 Society for Academic Emergency Medicine.)
- Published
- 2023
- Full Text
- View/download PDF
4. Reply to "Letter to the Editor, re: GRACE-2: Low-Risk, Recurrent Abdominal Pain in the Emergency Department".
- Author
-
Bellolio F, Broder JS, Oliveira J E Silva L, Freiermuth CE, Hooker E, Jang TB, Griffey RT, Meltzer AC, Mills AM, Pepper J, Prakken S, Repplinger MD, Upadhye S, and Carpenter CR
- Subjects
- Abdominal Pain diagnosis, Abdominal Pain etiology, Humans, Chest Pain, Emergency Service, Hospital
- Published
- 2022
- Full Text
- View/download PDF
5. Guidelines for Reasonable and Appropriate Care in the Emergency Department 2 (GRACE-2): Low-risk, recurrent abdominal pain in the emergency department.
- Author
-
Broder JS, Oliveira J E Silva L, Bellolio F, Freiermuth CE, Griffey RT, Hooker E, Jang TB, Meltzer AC, Mills AM, Pepper JD, Prakken SD, Repplinger MD, Upadhye S, and Carpenter CR
- Subjects
- Abdominal Pain diagnosis, Abdominal Pain etiology, Abdominal Pain therapy, Adult, Chest Pain, Emergency Service, Hospital, Humans, Chronic Pain, Emergency Medicine
- Abstract
This second Guideline for Reasonable and Appropriate Care in the Emergency Department (GRACE-2) from the Society for Academic Emergency Medicine is on the topic "low-risk, recurrent abdominal pain in the emergency department." The multidisciplinary guideline panel applied the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assess the certainty of evidence and strength of recommendations regarding four priority questions for adult emergency department patients with low-risk, recurrent, undifferentiated abdominal pain. The intended population includes adults with multiple similar presentations of abdominal signs and symptoms recurring over a period of months or years. The panel reached the following recommendations: (1) if a prior negative computed tomography of the abdomen and pelvis (CTAP) has been performed within 12 months, there is insufficient evidence to accurately identify populations in whom repeat CTAP imaging can be safely avoided or routinely recommended; (2) if CTAP with IV contrast is negative, we suggest against ultrasound unless there is concern for pelvic or biliary pathology; (3) we suggest that screening for depression and/or anxiety may be performed during the ED evaluation; and (4) we suggest an opioid-minimizing strategy for pain control. EXECUTIVE SUMMARY: The GRACE-2 writing group developed clinically relevant questions to address the care of adult patients with low-risk, recurrent, previously undifferentiated abdominal pain in the emergency department (ED). Four patient-intervention-comparison-outcome-time (PICOT) questions were developed by consensus of the writing group, who performed a systematic review of the literature and then synthesized direct and indirect evidence to formulate recommendations, following GRADE methodology. The writing group found that despite the commonality and relevance of these questions in emergency care, the quantity and quality of evidence were very limited, and even fundamental definitions of the population and outcomes of interest are lacking. Future research opportunities include developing precise and clinically relevant definitions of low-risk, recurrent, undifferentiated abdominal pain and determining the scope of the existing populations in terms of annual national ED visits for this complaint, costs of care, and patient and provider preferences., (© 2022 Society for Academic Emergency Medicine.)
- Published
- 2022
- Full Text
- View/download PDF
6. Advanced practice providers in academic emergency medicine: A national survey of chairs and program directors.
- Author
-
Carpenter CR, Abrams S, Courtney DM, Dorner SC, Dyne P, Elia T, Jourdan DN, Kaji AH, Martin IBK, Mills AM, Nagasawa K, Pillow M, Reznek M, Starnes A, Temin E, Wolfe R, and Chekijian S
- Subjects
- Academic Medical Centers, Humans, Surveys and Questionnaires, United States, Emergency Medicine education, Internship and Residency, Nurse Practitioners, Physician Assistants
- Abstract
Background: The Society for Academic Emergency Medicine Board of Directors convened a task force to elucidate the current state of workforce, operational, and educational issues being faced by academic medical centers related to advanced practice providers (APPs). The task force surveyed academic emergency department (ED) chairs and residency program directors (PDs)., Methods: The survey was distributed to the Association of Academic Chairs of Emergency Medicine (AACEM)-member chairs and their respective residency PDs in 2021. We surveyed 125 chairs with their self-identified PDs. The survey sampled hiring, state-independent practice laws, scope of practice, teaching and supervision, training opportunities, delegation of procedures between physician learners and APPs, and perceptions of the impact on resident and medical student education., Results: Of the AACEM-member chairs identified, 73% responded and 47% of PDs responded. Most (98%) employ either physician assistants or nurse practitioners. Among responding departments, 86% report APPs working in fast-track settings, 80% work in the main ED, and 54% work in the waiting room. In 44% of departments, APPs and residents evaluate patients concurrently, and 2% of respondents reported that APPs manage high-acuity patients without attending involvement. Two-thirds of chairs believe that APPs contribute positively to the quality of patient care, while 44% believe that APPs contribute to the academic environment. One-third of PDs believe that the presence of APPs interferes with resident education. Although 75% of PDs believe that residents require training to work effectively with APPs in the ED, almost half (49%) report zero hours of training around APP supervision or collaborative skills., Conclusions: APPs are ubiquitous across academic EDs. Future research is required for academic ED leaders to balance physician and APP deployment across the academic ED within the context of patient care, resident education, institutional resources, professional development opportunities for APP staff, and standardization of APP EM training., (© 2021 by the Society for Academic Emergency Medicine.)
- Published
- 2022
- Full Text
- View/download PDF
7. COVID-19: A NYC Department Chair's Perspective.
- Author
-
Mills AM
- Published
- 2020
- Full Text
- View/download PDF
8. Unconditional Care in Academic Emergency Departments.
- Author
-
Kline JA, Burton JH, Carpenter CR, Meisel ZF, Miner JR, Newgard CD, Quest T, Martin IBK, Holmes JF, Kaji AH, Bird SB, Coates WC, Lall MD, Mills AM, Ranney ML, Wolfe RE, and Dorner SC
- Subjects
- Betacoronavirus, COVID-19, Humans, Pandemics, SARS-CoV-2, United States, Academic Medical Centers organization & administration, Coronavirus Infections therapy, Emergency Service, Hospital organization & administration, Pneumonia, Viral therapy
- Published
- 2020
- Full Text
- View/download PDF
9. In Reply.
- Author
-
Bennett CL, Raja AS, Kass D, Gross N, and Mills AM
- Subjects
- Humans, Sex Factors, United States, Faculty
- Published
- 2019
- Full Text
- View/download PDF
10. Feedback With Performance Metric Scorecards Improves Resident Satisfaction but Does Not Impact Clinical Performance.
- Author
-
Mamtani M, Shofer FS, Sackeim A, Conlon L, Scott K, and Mills AM
- Abstract
Objectives: The Emergency Medicine Milestone Project, a framework for assessing competencies, has been used as a method of providing focused resident feedback. However, the emergency medicine milestones do not include specific objective data about resident clinical efficiency and productivity, and studies have shown that milestone-based feedback does not improve resident satisfaction with the feedback process. We examined whether providing performance metric reports to resident physicians improves their satisfaction with the feedback process and their clinical performance., Methods: We conducted a three-phase stepped-wedge randomized pilot study of emergency medicine residents at a single, urban academic site. In phase 1, all residents received traditional feedback; in phase 2, residents were randomized to receive traditional feedback (control group) or traditional feedback with performance metric reports (intervention group); and in phase 3, all residents received monthly performance metric reports and traditional feedback. To assess resident satisfaction with the feedback process, surveys using 6-point Likert scales were administered at each study phase and analyzed using two-sample t-tests. Analysis of variance in repeated measures was performed to compare impact of feedback on resident clinical performance, specifically patient treatment time (PTT) and patient visits per hour., Results: Forty-one residents participated in the trial of which 21 were randomized to the intervention group and 20 in the control group. Ninety percent of residents liked receiving the report and 74% believed that it better prepared them for expectations of becoming an attending physician. Additionally, residents randomized to the intervention group reported higher satisfaction (p = 0.01) with the quality of the feedback compared to residents in the control group. However, receiving performance metric reports, regardless of study phase or postgraduate year status, did not affect clinical performance, specifically PTT (183 minutes vs. 177 minutes, p = 0.34) or patients visits per hour (0.99 vs. 1.04, p = 0.46)., Conclusions: While feedback with performance metric reports did not improve resident clinical performance, resident physicians were more satisfied with the feedback process, and a majority of residents expressed liking the reports and felt that it better prepared them to become attending physicians. Residency training programs could consider augmenting feedback with performance metric reports to aide in the transition from resident to attending physician., (© 2019 by the Society for Academic Emergency Medicine.)
- Published
- 2019
- Full Text
- View/download PDF
11. Gender Differences in Faculty Rank Among Academic Emergency Physicians in the United States.
- Author
-
Bennett CL, Raja AS, Kapoor N, Kass D, Blumenthal DM, Gross N, and Mills AM
- Subjects
- Adult, Aged, Faculty, Medical classification, Female, Humans, Logistic Models, Male, Middle Aged, Research Support as Topic statistics & numerical data, Sex Distribution, United States, Emergency Medicine statistics & numerical data, Faculty, Medical statistics & numerical data, Physicians, Women statistics & numerical data
- Abstract
Background: The purpose of this study was to complete a comprehensive analysis of gender differences in faculty rank among U.S. emergency physicians that reflected all academic emergency physicians., Methods: We assembled a comprehensive list of academic emergency medicine (EM) physicians with U.S. medical school faculty appointments from Doximity.com linked to detailed information on physician gender, age, years since residency completion, scientific authorship, National Institutes of Health (NIH) research funding, and participation in clinical trials. To estimate gender differences in faculty rank, multivariable logistic regression models were used that adjusted for these factors., Results: Our study included 3,600 academic physicians (28%, or 1,016, female). Female emergency physicians were younger than their male colleagues (mean [±SD] age was 43.8 [±8.7] years for females and 47.4 [±9.9] years for males [p < 0.001]), had fewer years since residency completion (12.4 years vs. 15.6 years, p < 0.001), had fewer total and first/last author publications (4.7 vs. 8.6 total publications, p < 0.001; 4.3 vs. 7.1 first or last author publications, p < 0.001), and were less likely to be principal investigators on NIH grants (1.2% vs. 2.9%, p = 0.002) or clinical trials (1.8% vs. 4.4%, p < 0.001). In unadjusted analysis, male physicians were more likely than female physicians to hold the rank of associate or full professor versus assistant professor (13.7 percentage point difference, p < 0.001), a relationship that persisted after multivariable adjustment (5.5 percentage point difference, p = 0.001)., Conclusions: Female academic EM physicians are less likely to hold the rank of associate or full professor compared to male physicians even after detailed adjustment for other factors that may influence faculty rank., (© 2019 by the Society for Academic Emergency Medicine.)
- Published
- 2019
- Full Text
- View/download PDF
12. Developing a Research Agenda to Optimize Diagnostic Imaging in the Emergency Department: An Executive Summary of the 2015 Academic Emergency Medicine Consensus Conference.
- Author
-
Marin JR and Mills AM
- Subjects
- Clinical Competence, Clinical Decision-Making, Consensus Development Conferences as Topic, Diagnostic Imaging standards, Evidence-Based Emergency Medicine, Humans, Inservice Training, Knowledge, Patient Outcome Assessment, Diagnostic Imaging statistics & numerical data, Emergency Service, Hospital organization & administration, Health Services Research organization & administration
- Abstract
The 2015 Academic Emergency Medicine (AEM) consensus conference, "Diagnostic Imaging in the Emergency Department: A Research Agenda to Optimize Utilization," was held on May 12, 2015, with the goal of developing a high-priority research agenda on which to base future research. The specific aims of the conference were to: 1) understand the current state of evidence regarding emergency department (ED) diagnostic imaging utilization and identify key opportunities, limitations, and gaps in knowledge; 2) develop a consensus-driven research agenda emphasizing priorities and opportunities for research in ED diagnostic imaging; and 3) explore specific funding mechanisms available to facilitate research in ED diagnostic imaging. Over a 2-year period, the executive committee and other experts in the field convened regularly to identify specific areas in need of future research. Six content areas within emergency diagnostic imaging were identified prior to the conference and served as the breakout groups on which consensus was achieved: clinical decision rules; use of administrative data; patient-centered outcomes research; training, education, and competency; knowledge translation and barriers to imaging optimization; and comparative effectiveness research in alternatives to traditional computed tomography use. The executive committee invited key stakeholders to assist with planning and to participate in the consensus conference to generate a multidisciplinary agenda. There were 164 individuals involved in the conference spanning various specialties, including emergency medicine (EM), radiology, surgery, medical physics, and the decision sciences. This issue of AEM is dedicated to the proceedings of the 16th annual AEM consensus conference as well as original research related to emergency diagnostic imaging., (© 2015 by the Society for Academic Emergency Medicine.)
- Published
- 2015
- Full Text
- View/download PDF
13. Variation in Pediatric Cervical Spine Computed Tomography Radiation Dose Index.
- Author
-
Marin JR, Sengupta D, Bhargavan-Chatfield M, Kanal KM, Mills AM, and Applegate KE
- Subjects
- Adolescent, Child, Child, Preschool, Female, Humans, Infant, Male, Neck diagnostic imaging, Retrospective Studies, Cervical Vertebrae diagnostic imaging, Hospitals, Community statistics & numerical data, Hospitals, Pediatric statistics & numerical data, Radiation Dosage, Tomography, X-Ray Computed methods
- Abstract
Objectives: The objective was to evaluate variation in the current estimated radiation dose index for pediatric cervical spine (c-spine) computed tomography (CT) examinations., Methods: This was a retrospective analysis of pediatric (age younger than 19 years) c-spine CT examinations from the American College of Radiology Dose Index Registry, July 2011 through December 2014. We used the volume CT dose index (CTDIvol) as the radiation dose estimate and used summary statistics to describe patient and hospital characteristics., Results: There were 12,218 pediatric CT c-spine examinations performed across 296 participating hospitals. Fifty-six percent were in male patients, and 79% were in children older than 10 years. Most hospitals (55%) were community hospitals without trauma designations, and the largest proportion of examinations (41%) were performed at these hospitals. The median CTDIvol was 15 mGy (interquartile range = 9 to 23 mGy) representing a more than 2.5-fold difference between the 25th and 75th percentiles. Pediatric hospitals (both trauma and nontrauma centers) delivered the lowest CTDIvol across all age groups and showed the least amount of variability in dose., Conclusions: There is significant variation in the radiation dose index for pediatric c-spine CT examinations. Pediatric hospitals practice at lower CT dose estimates than other hospitals. Individual hospitals should examine their practices in an effort to ensure standardization and optimization of CT parameters to minimize radiation exposures to pediatric patients., (© 2015 by the Society for Academic Emergency Medicine.)
- Published
- 2015
- Full Text
- View/download PDF
14. Funding Research in Emergency Diagnostic Imaging: Summary of a Panel Discussion at the 2015 Academic Emergency Medicine Consensus Conference.
- Author
-
Cherney AR, Marin JR, Brown J, Anise A, Krosnick S, Henriksen K, Lewis RJ, and Mills AM
- Subjects
- Consensus Development Conferences as Topic, Emergency Medicine, Humans, Quality of Health Care, United States, Diagnostic Imaging statistics & numerical data, Emergency Service, Hospital organization & administration, Health Services Research organization & administration
- Abstract
As part of the 2015 Academic Emergency Medicine consensus conference "Diagnostic Imaging in the Emergency Department: A Research Agenda to Optimize Utilization," a panel of representatives from the National Institute of Health's Office of Emergency Care Research, the National Institute of Biomedical Imaging and Bioengineering, the Agency for Healthcare Research and Quality, and the Patient-Centered Outcomes Research Institute was assembled to discuss future opportunities for funding research in this particular area of interest. Representatives from these agencies and organizations discussed their missions and priorities and how they distribute funding. They also addressed questions on mechanisms for new and established researchers to secure future funding., (© 2015 by the Society for Academic Emergency Medicine.)
- Published
- 2015
- Full Text
- View/download PDF
15. Advancing Patient-centered Outcomes in Emergency Diagnostic Imaging: A Research Agenda.
- Author
-
Kanzaria HK, McCabe AM, Meisel ZM, LeBlanc A, Schaffer JT, Bellolio MF, Vaughan W, Merck LH, Applegate KE, Hollander JE, Grudzen CR, Mills AM, Carpenter CR, and Hess EP
- Subjects
- Consensus Development Conferences as Topic, Decision Making, Emergency Medicine, Humans, Patient-Centered Care, Diagnostic Imaging statistics & numerical data, Emergency Service, Hospital organization & administration, Health Services Research organization & administration, Patient Outcome Assessment
- Abstract
Diagnostic imaging is integral to the evaluation of many emergency department (ED) patients. However, relatively little effort has been devoted to patient-centered outcomes research (PCOR) in emergency diagnostic imaging. This article provides background on this topic and the conclusions of the 2015 Academic Emergency Medicine consensus conference PCOR work group regarding "Diagnostic Imaging in the Emergency Department: A Research Agenda to Optimize Utilization." The goal was to determine a prioritized research agenda to establish which outcomes related to emergency diagnostic imaging are most important to patients, caregivers, and other key stakeholders and which methods will most optimally engage patients in the decision to undergo imaging. Case vignettes are used to emphasize these concepts as they relate to a patient's decision to seek care at an ED and the care received there. The authors discuss applicable research methods and approaches such as shared decision-making that could facilitate better integration of patient-centered outcomes and patient-reported outcomes into decisions regarding emergency diagnostic imaging. Finally, based on a modified Delphi process involving members of the PCOR work group, prioritized research questions are proposed to advance the science of patient-centered outcomes in ED diagnostic imaging., (© 2015 by the Society for Academic Emergency Medicine.)
- Published
- 2015
- Full Text
- View/download PDF
16. To test or not to test … decision analysis of decision support.
- Author
-
Courtney DM, Mills AM, and Marin JR
- Subjects
- Female, Humans, Male, Radiography, Acute Coronary Syndrome diagnostic imaging, Acute Coronary Syndrome economics, Emergency Service, Hospital economics, Pulmonary Embolism diagnostic imaging, Pulmonary Embolism economics, Unnecessary Procedures economics
- Published
- 2015
- Full Text
- View/download PDF
17. Optimizing diagnostic imaging in the emergency department.
- Author
-
Mills AM, Raja AS, and Marin JR
- Subjects
- Consensus, Emergency Medicine education, Humans, Practice Guidelines as Topic, United States, Congresses as Topic, Diagnostic Imaging methods, Emergency Medicine organization & administration, Emergency Service, Hospital organization & administration
- Abstract
While emergency diagnostic imaging use has increased significantly, there is a lack of evidence for corresponding improvements in patient outcomes. Optimizing emergency department (ED) diagnostic imaging has the potential to improve the quality, safety, and outcomes of ED patients, but to date, there have not been any coordinated efforts to further our evidence-based knowledge in this area. The objective of this article is to discuss six aspects of diagnostic imaging to provide background information on the underlying framework for the 2015 Academic Emergency Medicine consensus conference, "Diagnostic Imaging in the Emergency Department: A Research Agenda to Optimize Utilization." The consensus conference aims to generate a high priority research agenda for emergency diagnostic imaging that will inform the design of future investigations. The six components herein will serve as the group topics for the conference: 1) patient-centered outcomes research; 2) clinical decision rules; 3) training, education, and competency; 4) knowledge translation and barriers to image optimization; 5) use of administrative data; and 6) comparative effectiveness research: alternatives to traditional CT use., (© 2015 by the Society for Academic Emergency Medicine.)
- Published
- 2015
- Full Text
- View/download PDF
18. Research priorities for the influence of gender on diagnostic imaging choices in the emergency department setting.
- Author
-
Ashurst JV, Cherney AR, Evans EM, Kennedy Hall M, Hess EP, Kline JA, Mitchell AM, Mills AM, Weigner MB, and Moore CL
- Subjects
- Abdominal Pain diagnosis, Abdominal Pain etiology, Acute Disease, Age Factors, Chest Pain diagnosis, Chest Pain etiology, Consensus, Emergency Medicine, Emergency Service, Hospital statistics & numerical data, Gender Identity, Health Services Research, Humans, Male, Risk Factors, Sex Factors, Decision Making, Diagnostic Imaging methods, Diagnostic Imaging statistics & numerical data, Emergency Service, Hospital organization & administration, Sex Characteristics
- Abstract
Diagnostic imaging is a cornerstone of patient evaluation in the acute care setting, but little effort has been devoted to understanding the appropriate influence of sex and gender on imaging choices. This article provides background on this issue and a description of the working group and consensus findings reached during the diagnostic imaging breakout session at the 2014 Academic Emergency Medicine consensus conference "Gender-specific Research in Emergency Care: Investigate, Understand, and Translate How Gender Affects Patient Outcomes." Our goal was to determine research priorities for how sex and gender may (or should) affect imaging choices in the acute care setting. Prior to the conference, the working group identified five areas for discussion regarding the research agenda in sex- and gender-based imaging using literature review and expert consensus. The nominal group technique was used to identify areas for discussion for common presenting complaints to the emergency department where ionizing radiation is often used for diagnosis: suspected pulmonary embolism, suspected kidney stone, lower abdominal pain with a concern for appendicitis, and chest pain concerning for coronary artery disease. The role of sex- and gender-based shared decision-making in diagnostic imaging decisions is also raised., (© 2014 by the Society for Academic Emergency Medicine.)
- Published
- 2014
- Full Text
- View/download PDF
19. The effect of an emergency department dedicated midtrack area on patient flow.
- Author
-
Soremekun OA, Shofer FS, Grasso D, Mills AM, Moore J, and Datner EM
- Subjects
- Adult, Female, Humans, Length of Stay, Male, Middle Aged, Outcome and Process Assessment, Health Care, Patient Acuity, Retrospective Studies, Time Factors, Crowding, Emergency Service, Hospital organization & administration, Patients' Rooms supply & distribution, Triage
- Abstract
Background: Emergency department (ED) crowding negatively affects quality of care and disproportionately affects medium-acuity (Emergency Severity Index [ESI] level 3) patients. The effect of a dedicated area in the ED focused on these patients has not been well studied., Objectives: The objective was to find out the operational effect of a midtrack area dedicated to the evaluation and safe disposition of uncomplicated medium-acuity (ESI 3) patients., Methods: This was a 24-month pre-/postintervention study to evaluate the effect of implementation of a dedicated midtrack area at an urban tertiary academic adult ED. The midtrack had three examination rooms and three hallway stretchers for ongoing treatment staffed by an attending physician and two registered nurses (RNs). Besides the two additional RNs representing a 3.4% increase in total daily nursing hours, the intervention required no additional ED resources. The midtrack area was open from 1 p.m. to 9 p.m. on weekdays, corresponding to peak ED arrival rates. All patients presenting during weekdays were included, excluding patients triaged directly to the trauma bay or psychiatric unit or who expired in the ED. The main outcomes were left without being seen (LWBS) rates and ED length of stay (LOS), adjusting for patient volume, daily total patient hours (a proxy for ED crowding), and acuity., Results: A total of 91,903 patients were included for analysis during the study period including 261 pre- and 256 postintervention days. Comparing the pre- and postintervention periods, mean ED daily visits (173 vs. 182) and mean total daily patient hours (889 vs. 942) were all significantly higher in the postintervention period (p<0.0001). There was no significant change in percentage of patients with high triage acuity levels. Despite this increase in volume and crowding, the unadjusted and adjusted LWBS rates decreased from 6.85% to 4.46% (p<0.0001) and from 7.33% to 3.97% (p<0.0001), respectively. The mean LOS for medium-acuity patients also decreased by 39.2 minutes (p<0.0001). For high-acuity patients, there was no significant change in the mean time to room (14.69 minutes vs. 15.21 minutes, p=0.07); however, their mean LOS increased by 24 minutes (331 minutes vs. 355 minutes, p<0.0001)., Conclusions: Implementation of a midtrack area dedicated to caring for uncomplicated medium-acuity (ESI 3) patients was associated with a decrease in overall ED LWBS rates and ED LOS for medium-acuity patients., (© 2014 by the Society for Academic Emergency Medicine.)
- Published
- 2014
- Full Text
- View/download PDF
20. Neurological and psychiatric tolerability of rilpivirine (TMC278) vs. efavirenz in treatment-naïve, HIV-1-infected patients at 48 weeks.
- Author
-
Mills AM, Antinori A, Clotet B, Fourie J, Herrera G, Hicks C, Madruga JV, Vanveggel S, Stevens M, and Boven K
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Alkynes, Anti-HIV Agents pharmacology, Anti-HIV Agents therapeutic use, Benzoxazines administration & dosage, Benzoxazines therapeutic use, Cyclopropanes, HIV Infections psychology, HIV Infections virology, Humans, Middle Aged, Nitriles administration & dosage, Nitriles therapeutic use, Pyrimidines administration & dosage, Pyrimidines therapeutic use, Rilpivirine, Viral Load physiology, Young Adult, Anti-HIV Agents administration & dosage, Benzoxazines adverse effects, HIV Infections drug therapy, HIV-1 drug effects, HIV-1 physiology, Mental Disorders chemically induced, Nervous System Diseases chemically induced, Nitriles adverse effects, Pyrimidines adverse effects
- Abstract
Objectives: The aim of the study was to compare the neuropsychiatric safety and tolerability of rilpivirine (TMC278) vs. efavirenz in a preplanned pooled analysis of data from the ECHO and THRIVE studies which compared the safety and efficacy of the two drugs in HIV-1 infected treatment naïve adults., Methods: ECHO and THRIVE were randomized, double-blind, double-dummy, 96-week, international, phase 3 trials comparing the efficacy, safety and tolerability of rilpivirine 25 mg vs. efavirenz 600 mg once daily in combination with two background nucleoside/tide reverse transcriptase inhibitors. Safety and tolerability analyses were conducted when all patients had received at least 48 weeks of treatment or discontinued earlier. Differences between treatments in the incidence of neurological and psychiatric adverse events (AEs) of interest were assessed in preplanned statistical analyses using Fisher's exact test., Results: At the time of the week 48 analysis, the cumulative incidences in the rilpivirine vs. efavirenz groups of any grade 2-4 treatment-related AEs and of discontinuation because of AEs were 16% vs. 31% (P<0.0001) and 3% vs. 8% (P=0.0005), respectively. The incidence of treatment-related neuropsychiatric AEs was 27% vs. 48%, respectively (P<0.0001). The incidence of treatment-related neurological AEs of interest was 17% vs. 38% (P<0.0001), and that of treatment-related psychiatric AEs of interest was 15% vs. 23% (P=0.0002). Dizziness and abnormal dreams/nightmares occurred significantly less frequently with rilpivirine vs. efavirenz (P<0.01). In both groups, patients with prior neuropsychiatric history tended to report more neuropsychiatric AEs but rates remained lower for rilpivirine than for efavirenz., Conclusions: Rilpivirine was associated with fewer neurological and psychiatric AEs of interest than efavirenz over 48 weeks in treatment-naïve, HIV-1-infected adults., (© 2013 British HIV Association.)
- Published
- 2013
- Full Text
- View/download PDF
21. Overuse of computed tomography pulmonary angiography in the evaluation of patients with suspected pulmonary embolism in the emergency department.
- Author
-
Crichlow A, Cuker A, and Mills AM
- Subjects
- Academic Medical Centers, Adult, Biomarkers blood, Cohort Studies, Female, Humans, Incidence, Male, Middle Aged, Pennsylvania, Prospective Studies, Pulmonary Embolism blood, Pulmonary Embolism diagnosis, Urban Population, Angiography statistics & numerical data, Emergency Service, Hospital, Fibrin Fibrinogen Degradation Products analysis, Pulmonary Embolism diagnostic imaging, Tomography, X-Ray Computed statistics & numerical data, Unnecessary Procedures statistics & numerical data
- Abstract
Background: Clinical decision rules have been developed and validated for the evaluation of patients presenting with suspected pulmonary embolism (PE) to the emergency department (ED)., Objectives: The objective was to assess the percentage of computed tomographic pulmonary angiography (CT-PA) procedures that could have been avoided by use of the Wells score coupled with D-dimer testing (Wells/D-dimer) or pulmonary embolism rule-out criteria (PERC) in ED patients with suspected PE., Methods: The authors conducted a prospective cohort study of adult ED patients undergoing CT-PA for suspected PE. Wells score and PERC were calculated. A research blood sample was obtained for D-dimer testing for subjects who did not undergo testing as part of their ED evaluation. The primary outcome was PE by CT-PA or 90-day follow-up. Secondary outcomes were ED length of stay (LOS) and CT-PA time as defined by time from order to initial radiologist interpretation., Results: Of 152 suspected PE subjects available for analysis (mean ± SD age = 46.3 ± 15.6 years, 74% female, 59% black or African American, 11.8% diagnosed with PE), 14 (9.2%) met PERC, none of whom were diagnosed with PE. A low-risk Wells score (≤4) was assigned to 110 (72%) subjects, of whom only 38 (35%) underwent clinical D-dimer testing (elevated in 33/38). Of the 72 subjects with low-risk Wells scores who did not have D-dimers performed in the ED, archived research samples were negative in 16 (22%). All 21 subjects with low-risk Wells scores and negative D-dimers were PE-negative. CT-PA time (median = 160 minutes) accounted for more than half of total ED LOS (median = 295 minutes)., Conclusions: In total, 9.2 and 13.8% of CT-PA procedures could have been avoided by use of PERC and Wells/D-dimer, respectively., (© 2012 by the Society for Academic Emergency Medicine.)
- Published
- 2012
- Full Text
- View/download PDF
22. Diagnostic characteristics of S100A8/A9 in a multicenter study of patients with acute right lower quadrant abdominal pain.
- Author
-
Mills AM, Huckins DS, Kwok H, Baumann BM, Ruddy RM, Rothman RE, Schrock JW, Lovecchio F, Krief WI, Hexdall A, Caspari R, Cohen B, and Lewis RJ
- Subjects
- Abdominal Pain surgery, Adolescent, Adult, Appendectomy, Appendicitis surgery, Biomarkers blood, Diagnosis, Differential, Double-Blind Method, Emergency Service, Hospital, Enzyme-Linked Immunosorbent Assay, Female, Humans, Linear Models, Male, Mass Screening methods, Prospective Studies, ROC Curve, Sensitivity and Specificity, Abdominal Pain diagnosis, Appendicitis diagnosis, Leukocyte L1 Antigen Complex blood
- Abstract
Objectives: Over the past decade, clinicians have become increasingly reliant on computed tomography (CT) for the evaluation of patients with suspected acute appendicitis. To limit the radiation risks and costs of CT, investigators have searched for biomarkers to aid in diagnostic decision-making. We evaluated one such biomarker, calprotectin or S100A8/A9, and determined the diagnostic performance characteristics of a developmental biomarker assay in a multicenter investigation of patients presenting with acute right lower quadrant abdominal pain., Methods: This was a prospective, double-blinded, single-arm, multicenter investigation performed in 13 emergency departments (EDs) from August 2009 to April 2010 of patients presenting with acute right lower quadrant abdominal pain. Plasma samples were tested using the investigational S100A8/A9 assay. The primary outcome of acute appendicitis was determined by histopathology for patients undergoing appendectomy or 2-week telephone follow-up for patients discharged without surgery. The sensitivity, specificity, negative likelihood ratio (LR-), and positive likelihood ratio (LR+) of the biomarker assay were calculated using the prespecified cutoff value of 14 units. A post hoc stability study was performed to investigate the potential effect of time and courier transport on the measured value of the S100A8/A9 assay test results., Results: Of 1,052 enrolled patients, 848 met criteria for analysis. The median age was 24.5 years (interquartile range [IQR] = 16-38 years), 57% were female, and 50% were white. There was a 27.5% prevalence of acute appendicitis. The sensitivity and specificity for the investigational S100A8/A9 assay in diagnosing acute appendicitis were estimated to be 96% (95% confidence interval [CI] = 93% to 98%) and 16% (95% CI = 13% to 19%), respectively. The LR- ratio was 0.24 (95% CI = 0.12 to 0.47), and the LR+ was 1.14 (95% CI = 1.10 to 1.19). The post hoc stability study demonstrated that in the samples that were shipped, the estimated time coefficient was 7.6 × 10(-3) ± 2.0 × 10(-3) log units/hour, representing an average increase of 43% in the measured value over 48 hours; in the samples that were not shipped, the estimated time coefficient was 2.5 × 10(-3) ± 0.4 × 10(-3) log units/hour, representing a 13% increase on average in the measured value over 48 hours, which was the maximum delay allowed by the study protocol. Thus, adjusting the cutoff value of 14 units by the magnitude of systematic inflation observed in the stability study at 48 hours would result in a new cutoff value of 20 units and a "corrected" sensitivity and specificity of 91 and 28%, respectively., Conclusions: In patients presenting with acute right lower quadrant abdominal pain, we found the investigational enzyme-linked immunosorbent assay (ELISA) test for S100A8/A9 to perform with high sensitivity but very limited specificity. We found that shipping effect and delay in analysis resulted in a subsequent rise in test values, thereby increasing the sensitivity and decreasing the specificity of the test. Further investigation with hospital-based laboratory analyzers is the next critical step for determining the ultimate clinical utility of the ELISA test for S100A8/A9 in ED patients presenting with acute right lower quadrant abdominal pain., (© 2012 by the Society for Academic Emergency Medicine.)
- Published
- 2012
- Full Text
- View/download PDF
23. Evaluation of a novel wound closure device: a multicenter randomized controlled trial.
- Author
-
Singer AJ, Chale S, Giardano P, Hocker M, Cairns C, Hamilton R, Nadkarni M, Mills AM, and Hollander JE
- Subjects
- Adolescent, Adult, Chi-Square Distribution, Female, Humans, Male, Polyesters, Treatment Outcome, Cyanoacrylates therapeutic use, Emergency Service, Hospital, Surgical Mesh, Surgical Wound Dehiscence prevention & control, Tissue Adhesives therapeutic use
- Abstract
Objectives: A novel wound closure device combining a mesh tape and octylcyanoacrylate (OCA) topical skin adhesive (TSA) was developed to facilitate wound closure and enhance the adhesive's strength. The objective of this study was to determine whether the incidence of wound dehiscence after laceration repair with the new device was equivalent to that after use of a high-viscosity OCA. We hypothesized that the rate of complete wound edge apposition would be equivalent for the two closure devices., Methods: This was a multicenter, randomized clinical trial in nine academic and community emergency departments (EDs) and urgent care centers. Patients with simple traumatic lacerations were included. Lacerations were randomly closed with a high-viscosity OCA or mesh tape-OCA combination. The rate of complete wound edge apposition at 14 days, rates of wound infection at 14 and 30 days, and the percentage of optimally appearing scars at 30 days after closure were assessed. Assuming a maximal clinically acceptable difference for equivalence of 8% in the rate of completely apposed wound edges, a sample of at least 138 patients in the tape-OCA group and at least 69 in the OCA-only group would give 80% power and a one-sided significance level of 5%., Results: During the study period the investigators enrolled 216 subjects, of whom 143 were randomized to the tape-OCA combination and 73 to the OCA-only group. Most wounds were located on the face and the upper extremities. Mean laceration length was similar in patients in both groups (tape-OCA 2.1 cm vs. OCA-only 2.0 cm; difference 0.1 cm, 95% confidence interval [CI] = -0.45 to 0.58 cm). The rate of complete wound edge apposition at 14 days was higher in wounds treated with the tape-OCA combination than in wounds treated with OCA alone (86.0% vs. 78.1%). The upper bound of the one-sided CI was 1.0% for the intention-to-treat population, which was less than the predetermined acceptable difference of less than 8%. There were no between-group differences in rates of infection and optimally appearing scars., Conclusions: When compared with OCA alone, the novel tape-OCA combination is equivalent with regard to complete wound edge apposition and cosmetic appearance., (© 2011 by the Society for Academic Emergency Medicine.)
- Published
- 2011
- Full Text
- View/download PDF
24. Generational influences in academic emergency medicine: teaching and learning, mentoring, and technology (part I).
- Author
-
Mohr NM, Moreno-Walton L, Mills AM, Brunett PH, and Promes SB
- Subjects
- Academic Medical Centers, Advisory Committees, Delphi Technique, Emergency Service, Hospital, Humans, Learning, Life Style, Medical Informatics, Societies, Medical, Teaching, Emergency Medicine education, Intergenerational Relations, Interprofessional Relations
- Abstract
For the first time in history, four generations are working together-traditionalists, baby boomers, generation Xers (Gen Xers), and millennials. Members of each generation carry with them a unique perspective of the world and interact differently with those around them. Through a review of the literature and consensus by modified Delphi methodology of the Society for Academic Emergency Medicine Aging and Generational Issues Task Force, the authors have developed this two-part series to address generational issues present in academic emergency medicine (EM). Understanding generational characteristics and mitigating strategies can help address some common issues encountered in academic EM. Through recognition of the unique characteristics of each of the generations with respect to teaching and learning, mentoring, and technology, academicians have the opportunity to strategically optimize interactions with one another., (© 2011 by the Society for Academic Emergency Medicine.)
- Published
- 2011
- Full Text
- View/download PDF
25. The effect of emergency department crowding on analgesia in patients with back pain in two hospitals.
- Author
-
Pines JM, Shofer FS, Isserman JA, Abbuhl SB, and Mills AM
- Subjects
- Adult, Female, Health Services Research, Hospitals, Community, Hospitals, University, Humans, Length of Stay statistics & numerical data, Linear Models, Male, Middle Aged, Multivariate Analysis, Outcome Assessment, Health Care, Quality of Health Care statistics & numerical data, Regression Analysis, Retrospective Studies, Statistics, Nonparametric, Time Factors, Triage statistics & numerical data, Analgesia statistics & numerical data, Back Pain drug therapy, Crowding, Emergency Service, Hospital statistics & numerical data, Emergency Treatment statistics & numerical data
- Abstract
Objectives: The authors assessed the association between measures of emergency department (ED) crowding and treatment with analgesia and delays to analgesia in ED patients with back pain., Methods: This was a retrospective cohort study of nonpregnant patients who presented to two EDs (an academic ED and a community ED in the same health system) from July 1, 2003, to February 28, 2007, with a chief complaint of "back pain." Each patient had four validated crowding measures assigned at triage. Main outcomes were the use of analgesia and delays in time to receiving analgesia. Delays were defined as greater than 1 hour to receive any analgesia from the triage time and from the room placement time. The Cochrane-Armitage test for trend, the Cuzick test for trend, and relative risk (RR) regression were used to test the effects of crowding on outcomes., Results: A total of 5,616 patients with back pain presented to the two EDs over the study period (mean+/-SD age=44+/-17 years, 57% female, 62% black or African American). Of those, 4,425 (79%) received any analgesia while in the ED. A total of 3,589 (81%) experienced a delay greater than 1 hour from triage to analgesia, and 2,985 (67%) experienced a delay more than 1 hour from room placement to analgesia. When hospitals were analyzed separately, a higher proportion of patients experienced delays at the academic site compared with the community site for triage to analgesia (87% vs. 74%) and room to analgesia (71% vs. 63%; both p<0.001). All ED crowding measures were associated with a higher likelihood for delays in both outcomes. At the academic site, patients were more likely to receive analgesia at the highest waiting room numbers. There were no other differences in ED crowding and likelihood of receiving medications in the ED at the two sites. These associations persisted in the adjusted analysis after controlling for potential confounders of analgesia administration., Conclusions: As ED crowding increases, there is a higher likelihood of delays in administration of pain medication in patients with back pain. Analgesia administration was not related to three measures of ED crowding; however, patients were actually more likely to receive analgesics when the waiting room was at peak levels in the academic ED., (Copyright (c) 2010 by the Society for Academic Emergency Medicine.)
- Published
- 2010
- Full Text
- View/download PDF
26. The association between emergency department crowding and analgesia administration in acute abdominal pain patients.
- Author
-
Mills AM, Shofer FS, Chen EH, Hollander JE, and Pines JM
- Subjects
- Acute Disease, Adult, Biomarkers analysis, Female, Humans, Male, Pain Measurement, Prospective Studies, Triage, Abdominal Pain drug therapy, Analgesics administration & dosage, Crowding, Emergency Service, Hospital organization & administration
- Abstract
Objectives: The authors assessed the effect of emergency department (ED) crowding on the nontreatment and delay in treatment for analgesia in patients who had acute abdominal pain., Methods: This was a secondary analysis of prospectively enrolled nonpregnant adult patients presenting to an urban teaching ED with abdominal pain during a 9-month period. Each patient had four validated crowding measures assigned at triage. Main outcomes were the administration of and delays in time to analgesia. A delay was defined as waiting more than 1 hour for analgesia. Relative risk (RR) regression was used to test the effects of crowding on outcomes., Results: A total of 976 abdominal pain patients (mean [+/-standard deviation] age = 41 [+/-16.6] years; 65% female, 62% black) were enrolled, of whom 649 (67%) received any analgesia. Of those treated, 457 (70%) experienced a delay in analgesia from triage, and 320 (49%) experienced a delay in analgesia after room placement. After adjusting for possible confounders of the ED administration of analgesia (age, sex, race, triage class, severe pain, final diagnosis of either abdominal pain not otherwise specified or gastroenteritis), increasing delays in time to analgesia from triage were independently associated with all four crowding measures, comparing the lowest to the highest quartile of crowding (total patient-care hours RR = 1.54, 95% confidence interval [CI] = 1.32 to 1.80; occupancy rate RR = 1.64, 95% CI = 1.42 to 1.91; inpatient number RR = 1.57, 95% CI = 1.36 to 1.81; and waiting room number RR = 1.53, 95% CI = 1.31 to 1.77). Crowding measures were not associated with the failure to treat with analgesia., Conclusions: Emergency department crowding is associated with delays in analgesic treatment from the time of triage in patients presenting with acute abdominal pain.
- Published
- 2009
- Full Text
- View/download PDF
27. Gender disparity in analgesic treatment of emergency department patients with acute abdominal pain.
- Author
-
Chen EH, Shofer FS, Dean AJ, Hollander JE, Baxt WG, Robey JL, Sease KL, and Mills AM
- Subjects
- Abdominal Pain classification, Abdominal Pain etiology, Adult, Biomarkers, Crowding, Female, Humans, Male, Middle Aged, Prospective Studies, Severity of Illness Index, Time Factors, Abdominal Pain drug therapy, Analgesia, Emergency Service, Hospital statistics & numerical data, Prejudice
- Abstract
Objectives: Oligoanalgesia for acute abdominal pain historically has been attributed to the provider's fear of masking serious underlying pathology. The authors assessed whether a gender disparity exists in the administration of analgesia for acute abdominal pain., Methods: This was a prospective cohort study of consecutive nonpregnant adults with acute nontraumatic abdominal pain of less than 72 hours' duration who presented to an urban emergency department (ED) from April 5, 2004, to January 4, 2005. The main outcome measures were analgesia administration and time to analgesic treatment. Standard comparative statistics were used., Results: Of the 981 patients enrolled (mean age +/- standard deviation [SD] 41 +/- 17 years; 65% female), 62% received any analgesic treatment. Men and women had similar mean pain scores, but women were less likely to receive any analgesia (60% vs. 67%, difference 7%, 95% confidence interval [CI] = 1.1% to 13.6%) and less likely to receive opiates (45% vs. 56%, difference 11%, 95% CI = 4.1% to 17.1%). These differences persisted when gender-specific diagnoses were excluded (47% vs. 56%, difference 9%, 95% CI = 2.5% to 16.2%). After controlling for age, race, triage class, and pain score, women were still 13% to 25% less likely than men to receive opioid analgesia. There was no gender difference in the receipt of nonopioid analgesia. Women waited longer to receive their analgesia (median time 65 minutes vs. 49 minutes, difference 16 minutes, 95% CI = 3.5 to 33 minutes)., Conclusions: Gender bias is a possible explanation for oligoanalgesia in women who present to the ED with acute abdominal pain. Standardized protocols for analgesic administration may ameliorate this discrepancy.
- Published
- 2008
- Full Text
- View/download PDF
28. The impact of a concurrent trauma alert evaluation on time to head computed tomography in patients with suspected stroke.
- Author
-
Chen EH, Mills AM, Lee BY, Robey JL, Zogby KE, Shofer FS, Reilly PM, and Hollander JE
- Subjects
- Adult, Aged, Aged, 80 and over, Craniocerebral Trauma complications, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Pennsylvania, Prospective Studies, Stroke complications, Time Factors, Tomography, X-Ray Computed, Craniocerebral Trauma diagnosis, Emergency Medicine methods, Emergency Medicine statistics & numerical data, Emergency Service, Hospital statistics & numerical data, Outcome and Process Assessment, Health Care, Stroke diagnostic imaging
- Abstract
Background: Emergency department (ED) overcrowding threatens quality of care by delaying the time to diagnosis and treatment of patients with time-sensitive diseases, such as acute stroke., Objective: The authors hypothesized that the presence of a trauma alert evaluation would impede the time to head computed tomography (hCT) in patients with stroke-like symptoms., Methods: This was a secondary analysis of prospectively collected data on patients with potential stroke who received an hCT in an urban trauma center ED from January 1, 2004, to November 30, 2004. Structured data collection included historical and examination items, National Institutes of Health (NIH) stroke scale score, laboratory and radiographic results, and final diagnosis. Admitted patients were followed in hospital. Patients who presented within one hour following a trauma evaluation were compared with patients who presented without concurrent trauma for triage time until completion of hCT. Chi-square, t-tests, and 95% confidence intervals (95% CIs) were used for comparisons., Results: The 171 patients enrolled had a mean (+/- standard deviation) age of 60.7 (+/- 7) years; 60% were female; and 58% were African American. Of these, 72 patients had a significant cerebrovascular event (38 [22%] ischemic stroke, 25 [15%] transient ischemic attack, seven [4%] intracranial hemorrhage, one [0.6%] subarachnoid hemorrhage, and one [0.6%] subdural hematoma). The remaining diagnoses included 4.6% migraine, 2.3% seizure, 2.9% syncope, 2.3% Bell's palsy, and 2.9% vertigo. There was no significant difference in time to hCT in patients who presented during a trauma activation and those who did not (99 minutes [interquartile range (IQR) = 24-156] vs. 101 minutes [IQR = 43-151.5]; p = 0.537). In subgroup analysis of patients with a significant cerebrovascular event, times to hCT were also similar (24 minutes [IQR = 12-99] vs. 61 minutes [IQR = 15-126]; p = 0.26)., Conclusions: In the authors' institution, the presence of concurrent trauma evaluation does not delay CT imaging of patients with potential stroke.
- Published
- 2006
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.