1. Current considerations for radiotherapy in HPV‐associated head and neck cancer
- Author
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Nadeem Riaz, Nancy Y. Lee, Sean McBride, and Linda Chen
- Subjects
Oncology ,medicine.medical_specialty ,medicine.medical_treatment ,Postoperative radiotherapy ,Clinical Trials, Phase II as Topic ,Internal medicine ,medicine ,Humans ,Human papillomavirus ,Papillomaviridae ,Definitive radiotherapy ,Randomized Controlled Trials as Topic ,business.industry ,Papillomavirus Infections ,Head and neck cancer ,Radiation dose ,virus diseases ,Radiotherapy Dosage ,General Medicine ,medicine.disease ,Radiation therapy ,Clinical Trials, Phase III as Topic ,Head and Neck Neoplasms ,Surgery ,business - Abstract
Human papillomavirus (HPV)-mediated oncogenesis confers increased sensitivity to radiotherapy and HPV head and neck cancer is associated with improved patient outcomes. As such, management of HPV-related head and neck cancer requires a multidisciplinary approach that balances maximizing locoregional control with minimizing treatment-related toxicity. We highlight considerations in radiation dose and target delineation, as well as considerations for chemoradiation, postoperative radiotherapy, and single modality, definitive radiotherapy. more...
- Published
- 2021
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