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Your search keyword '"Natalia Pallares"' showing total 4 results
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4 results on '"Natalia Pallares"'

1. Deciphering transplant outcomes of expanded kidney allografts donated after controlled circulatory death in the current transplant era. A call for caution

Author

Francesc Moreso, Nuria Montero, Néstor Toapanta, Edoardo Melilli, Josep M. Cruzado, Magali Giral, Irina B. Torres, Maarten Naesens, Ignacio Revuelta, Lluis Guirado, Jordi Comas, Beatriz Bardají, Alicia Molina Andujar, Natalia Pallares, Rafael Esteban, Fritz Diekmann, Gonzalo Velis, L. Riera, Marta Crespo, Anna Buxeda, Oriol Bestard, Anders Åsberg, Carme Facundo, Sergi Codina, and Maria Fiol

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, kidney transplantation, Kidney, survival analysis, Internal medicine, Epidemiology, medicine, Humans, Kidney transplantation, Dialysis, Survival analysis, Aged, Transplantation, business.industry, Proportional hazards model, Graft Survival, medicine.disease, Allografts, Kidney Transplantation, Tissue Donors, medicine.anatomical_structure, Cohort, epidemiology, Risk assessment, business
Abstract

Outcomes of kidney transplantation (KT) after controlled circulatory death (cDCD) with highly expanded criteria donors (ECD) and recipients have not been thoroughly evaluated. We analyzed in a multicenter cohort of 1161 consecutive KT, granular baseline donor and recipient factors predicting transplant outcomes, selected by bootstrapping and Cox proportional hazards, and were validated in a contemporaneous European KT cohort (n = 1585). 74.3% were DBD and 25.7% cDCD-KT. ECD-KT showed the poorest graft survival rates, irrespective of cDCD or DBD (log-rank

Published
2021

2. Author response for 'Safety of Oral Bisphosphonates in Moderate-to-Severe Chronic Kidney Disease: A Binational Cohort Analysis'

Author

Leena Elhussein, Julio Pascual, Daniel Dedman, Fergus J. Caskey, Daniel Prieto-Alhambra, Nigel Arden, María José Pérez-Sáez, Antonella Delmestri, Andrew Judge, M Sanni Ali, Xavier Nogués, Adolfo Diez-Perez, Yoav Ben-Shlomo, Cyrus Cooper, M Kassim Javaid, Natalia Pallares, Victoria Y Strauss, Cristian Tebé, Bo Abrahamsen, and Danielle E Robinson

Subjects
Moderate to severe, medicine.medical_specialty, Oral bisphosphonates, business.industry, Internal medicine, medicine, business, medicine.disease, Cohort study, Kidney disease
Published
2020

3. A propensity-score-matched analysis of laparoscopic vs open surgery for rectal cancer in a population-based study

Author

Josep Alfons Espinàs, Josep M. Borràs, Miguel Pera, L. Aliste, Sebastiano Biondo, R. Vernet, E. Targarona, E. Espin, A. Guarga, P. Manchon-Walsh, Natalia Pallares, and Universitat de Barcelona

Subjects
Male, Colorectal cancer, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Risk Factors, Medicine, Rectal cancer, Stage (cooking), Laparoscopy, Anàlisi, Proctectomy, medicine.diagnostic_test, Hazard ratio, Statistics, Gastroenterology, Middle Aged, Treatment Outcome, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Female, medicine.medical_specialty, Catalonia, Protective factor, 03 medical and health sciences, Estadístiques, Càncer colorectal, Internal medicine, Humans, Propensity Score, propensity-score analysis, Aged, Proportional Hazards Models, Retrospective Studies, Cirurgia, business.industry, Rectal Neoplasms, Assaying, Retrospective cohort study, Catalunya, medicine.disease, population-based, Laparoscòpia, Spain, Propensity score matching, Surgery, business
Abstract

Aim The oncological risk/benefit trade-off for laparoscopy in rectal cancer is controversial. Our aim was to compare laparoscopic vs open surgery for resection of rectal cancer, using unselected data from the public healthcare system of Catalonia (Spain). Methods This was a multicentre retrospective cohort study of all patients who had surgery with curative intent for primary rectal cancer at Catalonian public hospitals from 2011 to 2012. We obtained follow-up data for up to 5 years. To minimize the differences between the two groups, we performed propensity score matching on baseline patient characteristics. We used multivariate Cox proportional hazards regression analyses to assess locoregional relapse at 2 years and death at 2 and 5 years. Results Of 1513 patients with Stage I-III rectal cancer, 933 (61.7%) had laparoscopy (conversion rate 13.2%). After applying our propensity score matching strategy (2:1), 842 laparoscopy patients were matched to 517 open surgery patients. Multivariate Cox analysis of death at 2 years [hazard ratio (HR) 0.65, 95% CI 0.48, 0.87; P = 0.004] and 5 years (HR 0.61, 95% CI 0.5, 0.75; P < 0.001) and of local relapse at 2 years (HR 0.44, 95% CI 0.27, 0.72; P = 0.001) showed laparoscopy to be an independent protective factor compared with open surgery. Conclusions Laparoscopy results in lower locoregional relapse and long-term mortality in rectal cancer in unselected patients with all-risk groups included. Studies using long-term follow-up of cohorts and unselected data can provide information on clinically relevant outcomes to supplement randomized controlled trials.

Published
2019

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