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Your search keyword '"Qiu, Shuang-Jian"' showing total 25 results
Start Over Author "Qiu, Shuang-Jian" Publisher wiley
25 results on '"Qiu, Shuang-Jian"'

2. Arsenic trioxide induces differentiation of cancer stem cells in hepatocellular carcinoma through inhibition of LIF/JAK1/STAT3 and NF‐kB signaling pathways synergistically

Author

Zhang, Xin, primary, Hu, Bo, additional, Sun, Yun‐Fan, additional, Huang, Xiao‐Wu, additional, Cheng, Jian‐Wen, additional, Huang, Ao, additional, Zeng, Hai‐Ying, additional, Qiu, Shuang‐Jian, additional, Cao, Ya, additional, Fan, Jia, additional, Zhou, Jian, additional, and Yang, Xin‐Rong, additional

Published
2021
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3. Postoperative circulating tumor cells: An early predictor of extrahepatic metastases in patients with hepatocellular carcinoma undergoing curative surgical resection

Author

Sun, Yun‐Fan, primary, Wang, Peng‐Xiang, additional, Cheng, Jian‐Wen, additional, Gong, Zi‐Jun, additional, Huang, Ao, additional, Zhou, Kai‐Qian, additional, Hu, Bo, additional, Gao, Ping‐Ting, additional, Cao, Ya, additional, Qiu, Shuang‐Jian, additional, Zhou, Jian, additional, Fan, Jia, additional, Guo, Wei, additional, and Yang, Xin‐Rong, additional

Published
2020
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4. Chemotherapeutic perfusion of portal vein after tumor thrombectomy and hepatectomy benefits patients with advanced hepatocellular carcinoma: A propensity score‐matched survival analysis

Author

Gao, Yang, primary, Wang, Peng‐Xiang, additional, Cheng, Jian‐Wen, additional, Sun, Yun‐Fan, additional, Hu, Bo, additional, Guo, Wei, additional, Zhou, Kai‐Qian, additional, Yin, Yue, additional, Li, Yuan‐Cheng, additional, Wang, Jian, additional, Huang, Jun‐Feng, additional, Qiu, Shuang‐Jian, additional, Zhou, Jian, additional, Fan, Jia, additional, and Yang, Xin‐Rong, additional

Published
2019
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5. Establishment of a hepatocellular carcinoma patient‐derived xenograft platform and its application in biomarker identification

Author

Hu, Bo, primary, Li, Hong, additional, Guo, Wei, additional, Sun, Yun‐Fan, additional, Zhang, Xin, additional, Tang, Wei‐Guo, additional, Yang, Liu‐Xiao, additional, Xu, Yang, additional, Tang, Xiao‐Yan, additional, Ding, Guo‐Hui, additional, Qiu, Shuang‐Jian, additional, Zhou, Jian, additional, Li, Yi‐Xue, additional, Fan, Jia, additional, and Yang, Xin‐Rong, additional

Published
2019
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10. Circulating CD14+ HLA-DR−/low myeloid-derived suppressor cells predicted early recurrence of hepatocellular carcinoma after surgery

Author

Gao, Xing-Hui, primary, Tian, Lu, additional, Wu, Jiong, additional, Ma, Xiao-Lu, additional, Zhang, Chun-Yan, additional, Zhou, Yan, additional, Sun, Yun-Fan, additional, Hu, Bo, additional, Qiu, Shuang-jian, additional, Zhou, Jian, additional, Fan, Jia, additional, Guo, Wei, additional, and Yang, Xin-Rong, additional

Published
2017
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12. CC chemokine receptor-like 1 functions as a tumour suppressor by impairing CCR7-related chemotaxis in hepatocellular carcinoma

Author

Shi, Jie-Yi, primary, Yang, Liu-Xiao, additional, Wang, Zhi-Chao, additional, Wang, Ling-Yan, additional, Zhou, Jian, additional, Wang, Xiao-Ying, additional, Shi, Guo-Ming, additional, Ding, Zhen-Bin, additional, Ke, Ai-Wu, additional, Dai, Zhi, additional, Qiu, Shuang-Jian, additional, Tang, Qi-Qun, additional, Gao, Qiang, additional, and Fan, Jia, additional

Published
2014
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13. Human miR‐1228 as a stable endogenous control for the quantification of circulating microRNAs in cancer patients

Author

Hu, Jie, primary, Wang, Zheng, additional, Liao, Bo‐Yi, additional, Yu, Lei, additional, Gao, Xue, additional, Lu, Shaohua, additional, Wang, Shuyang, additional, Dai, Zhi, additional, Zhang, Xin, additional, Chen, Qing, additional, Qiu, Shuang‐Jian, additional, Wu, Ying, additional, Zhu, Hongguang, additional, Fan, Jia, additional, Zhou, Jian, additional, and Wang, Jiping, additional

Published
2014
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15. Intratumoral regulatory T cells with higher prevalence and more suppressive activity in hepatocellular carcinoma patients

Author

Wu, Han, primary, Chen, Pei, additional, Liao, Rui, additional, Li, Yi-Wei, additional, Yi, Yong, additional, Wang, Jia-Xing, additional, Cai, Xiao-Yan, additional, He, Hong-Wei, additional, Jin, Jian-Jun, additional, Cheng, Yun-Feng, additional, Fan, Jia, additional, Sun, Jian, additional, and Qiu, Shuang-Jian, additional

Published
2013
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16. High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery

Author

Shi, Ruo-Yu, primary, Yang, Xin-Rong, additional, Shen, Qiu-Jin, additional, Yang, Liu-Xiao, additional, Xu, Yang, additional, Qiu, Shuang-Jian, additional, Sun, Yun-Fan, additional, Zhang, Xin, additional, Wang, Zheng, additional, Zhu, Kai, additional, Qin, Wen-Xin, additional, Tang, Zhao-You, additional, Fan, Jia, additional, and Zhou, Jian, additional

Published
2012
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17. Overexpression of galectin-1 is associated with poor prognosis in human hepatocellular carcinoma following resection

Author

Wu, Han, primary, Chen, Pei, additional, Liao, Rui, additional, Li, Yi-Wei, additional, Yi, Yong, additional, Wang, Jia-Xing, additional, Sun, Tai-Wei, additional, Zhou, Jian, additional, Shi, Ying-Hong, additional, Yang, Xin-Rong, additional, Jin, Jian-Jun, additional, Cheng, Yun-Feng, additional, Fan, Jia, additional, and Qiu, Shuang-Jian, additional

Published
2012
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24. High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery.

Author

Shi RY, Yang XR, Shen QJ, Yang LX, Xu Y, Qiu SJ, Sun YF, Zhang X, Wang Z, Zhu K, Qin WX, Tang ZY, Fan J, and Zhou J

Subjects
Bile Duct Neoplasms mortality, Bile Duct Neoplasms pathology, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cholangiocarcinoma mortality, Cholangiocarcinoma pathology, Female, Humans, Intercellular Signaling Peptides and Proteins physiology, Male, Matrix Metalloproteinase 9 metabolism, Middle Aged, Neoplasm Invasiveness, Prognosis, Vascular Endothelial Growth Factor C metabolism, Bile Duct Neoplasms metabolism, Bile Ducts, Intrahepatic, Cholangiocarcinoma metabolism, Intercellular Signaling Peptides and Proteins metabolism, Lymphatic Metastasis
Abstract

Background: Dickkopf-related protein 1 (DKK1) has been reported involved in metastasis and invasion in several tumors. This study sought to investigate the prognostic value of DKK1 in intrahepatic cholangiocarcinoma (ICC) and its role in promoting ICC metastasis., Methods: Tissue microarrays of 138 ICC patient samples were employed to detect DKK1, vascular endothelial growth factor C (VEGF-C), and matrix metalloproteinase 9 (MMP9) expression using immunohistochemistry. The prognostic significances were assessed by Kaplan-Meier survival estimates. DKK1 expression was measured in an ICC cell line (HCCC-9810) and ICC tissues by immunofluorescence assay, quantitative real-time polymerase chain reaction, and western blot. Serum levels of DKK1 from 37 ICC patients were tested by enzyme-linked immunosorbent assay. The role of DKK1 in proliferation, migration, invasion, and gene expression regulation was assessed by DKK1 depletion using small interfering RNA., Results: Multivariate analyses revealed that DKK1 was an unfavorable predictor for overall survival and time to recurrence. The prognostic significance was retained in ICC patients with low recurrence risk (P < .05). DKK1 expression was elevated in an ICC cell line, tumor samples, and patient sera. High levels of DKK1 in ICC tissues correlated with elevated MMP9, VEGF-C, and metastasis of hepatic hilar lymph nodes. DKK1 depletion caused a decrease in cell migration and invasiveness, and down-regulation of MMP9 and VEGF-C expression., Conclusions: DKK1 is a novel prognostic biomarker for ICC, and it enhances tumor cell invasion and promotes lymph node metastasis of ICC through the induction of MMP9 and VEGF-C. DKK1 may be a potential therapeutic target for ICC., (Copyright © 2012 American Cancer Society.)

Published
2013
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25. Hepatitis B virus surface antigen-negative and hepatitis C virus antibody-negative hepatocellular carcinoma: clinical characteristics, outcome, and risk factors for early and late intrahepatic recurrence after resection.

Author

Li T, Qin LX, Gong X, Zhou J, Sun HC, Qiu SJ, Ye QH, Wang L, and Fan J

Subjects
Carcinoma, Hepatocellular immunology, Carcinoma, Hepatocellular mortality, Carcinoma, Hepatocellular surgery, Female, Hepatectomy, Humans, Liver Cirrhosis complications, Liver Neoplasms immunology, Liver Neoplasms mortality, Liver Neoplasms surgery, Male, Middle Aged, Neoplasm Recurrence, Local immunology, Prognosis, Retrospective Studies, Risk Factors, Carcinoma, Hepatocellular virology, Hepatitis B Surface Antigens analysis, Hepatitis C Antibodies analysis, Liver Neoplasms virology
Abstract

Background: Although the incidence of hepatitis B virus surface antigen (HBsAg)-negative/hepatitis C virus antibody (HCVAb)-negative hepatocellular carcinoma (NBNC-HCC) is gradually increasing, it has been mostly ignored in previous studies. The objective of this exploratory study was to investigate the clinicopathologic characteristics and prognostic factors that influence recurrence and survival in patients with NBNC-HCC., Methods: A retrospective analysis was performed of 675 patients with NBNC-HCC and 3529 patients with HBsAg-positive/HCVAb-negative HCC (BNC-HCC) who underwent curative resection between 1997 and 2009. Intrahepatic recurrences were classified into early (≤1 year) and late (>1 year) recurrences. Multivariate competing risks analyses with Bonferroni correction were used to evaluate independent prognostic factors., Results: There were no significant differences between the NBNC-HCC and BNC-HCC groups regarding overall survival, cumulative incidence of HCC-specific death, and recurrence. However, the patients with NBNC-HCC were much older (P < .001), were associated less often with cirrhosis or elevated α-fetoprotein levels (P < .001), and had a much lower ratio of men to women (P < .001). NBNC-HCC tumors were larger (P < .001), but were involved less often with vascular invasion (P = .004). Women, serum γ-glutamyl transpeptidase level, tumor size, tumor capsule, and tumor differentiation were identified as independent risk factors for HCC-specific survival in patients with NBNC-HCC. The cumulative incidence of HCC-specific death for women with NBNC-HCC was significantly greater than for men with NBNC-HCC (P < .001).Tumor capsule and vascular invasion were identified as independent risk factors for early recurrence of NBNC-HCC, whereas tumor differentiation was identified as the only significant risk factor for late recurrence., Conclusions: Patients who had NBNC-HCC had characteristics and prognostic factors that differed from those in patients who had BNC-HCC. Women with NBNC-HCC should be more closely monitored, and it may be worthwhile to evaluate estrogen administration for the maintenance of sex hormone balance and to improve these poor outcomes., (Copyright © 2012 American Cancer Society.)

Published
2013
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