Author: "Regateiro, Frederico S." / Publisher: wiley - Searchworks@Jio Institute Digital Library Search Results

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1. Regional, sex, and age inequities in asthma hospital admissions in Spain and Portugal

Author: Vieira, Rafael José, primary, Pereira, Ana Margarida, additional, Taborda‐Barata, Luís, additional, Regateiro, Frederico S., additional, Marques‐Cruz, Manuel, additional, Robalo Cordeiro, Carlos, additional, Loureiro, Cláudia Chaves, additional, Dávila, Ignacio J., additional, Bousquet, Jean, additional, Fonseca, João A., additional, and Sousa‐Pinto, Bernardo, additional
Published: 2024
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2. Patient‐centred digital biomarkers for allergic respiratory diseases and asthma: the ARIA‐EAACI approach

Author: Bousquet, Jean, Shamji, Mohamed H., Anto, Josep M., Schünemann, Holger J., Canonica, G. Walter, Jutel, Marek, Del Giacco, Stefano, Zuberbier, Torsten, Pfaar, Oliver, Fonseca, Joao A., Sousa‐Pinto, Bernardo, Klimek, Ludger, Czarlewski, Wienczyslawa, Bedbrook, Anna, Amaral, Rita, Ansotegui, Ignacio J., Bosnic‐Anticevich, Sinthia, Braido, Fulvio, Loureiro, Claudia Chaves, Gemicioglu, Bilun, Haahtela, Tari, Kulus, Marek, Kuna, Piotr, Kupczyk, Maciej, Matricardi, Paolo M., Regateiro, Frederico S., Samolinski, Boleslaw, Sofiev, Mikhail, Toppila‐Salmi, Sanna, Valiulis, Arunas, Ventura, Maria Teresa, Barbara, Cristina, Bergmann, Karl C., Bewick, Michael, Blain, Hubert, Bonini, Matteo, Boulet, Louis‐Philippe, Bourret, Rodolphe, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Cardona, Victoria, Casale, Thomas, Cecchi, Lorenzo, Charpin, Denis, Cherrez‐Ojeda, Ivan, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., Devillier, Philippe, Dramburg, Stephanie, Fokkens, Wytske J., Gotua, Maia, Heffler, Enrico, Ispayeva, Zhanat, Ivancevich, Juan Carlos, Joos, Guy, Kaidashev, Igor, Kraxner, Helga, Kvedariene, Violeta, Larenas‐Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga, Louis, Renaud, Makela, Mika, Makris, Michael, Maurer, Marcus, Melén, Erik, Micheli, Yann, Morais‐Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Olze, Heidi, Papadopoulos, Nikolaos G., Papi, Alberto, Patella, Vincenzo, Pétré, Benoit, Pham‐Thi, Nhân, Puggioni, Francesca, Quirce, Santiago, Roche, Nicolas, Rouadi, Philip W., Sá‐Sousa, Ana, Sagara, Hironori, Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sova, Milan, Ulrik, Charlotte Suppli, Taborda‐Barata, Luis, Todo‐Bom, Ana, Torres, Maria J., Tsiligianni, Ioanna, Usmani, Omar S., Valovirta, Erkka, Vasankari, Tuula, Vieira, Rafael José, Wallace, Dana, Waserman, Susan, Zidarn, Mihaela, Yorgancioglu, Arzu, Zhang, Luo, Chivato, Tomas, Ollert, Markus, Bousquet, Jean, Shamji, Mohamed H., Anto, Josep M., Schünemann, Holger J., Canonica, G. Walter, Jutel, Marek, Del Giacco, Stefano, Zuberbier, Torsten, Pfaar, Oliver, Fonseca, Joao A., Sousa‐Pinto, Bernardo, Klimek, Ludger, Czarlewski, Wienczyslawa, Bedbrook, Anna, Amaral, Rita, Ansotegui, Ignacio J., Bosnic‐Anticevich, Sinthia, Braido, Fulvio, Loureiro, Claudia Chaves, Gemicioglu, Bilun, Haahtela, Tari, Kulus, Marek, Kuna, Piotr, Kupczyk, Maciej, Matricardi, Paolo M., Regateiro, Frederico S., Samolinski, Boleslaw, Sofiev, Mikhail, Toppila‐Salmi, Sanna, Valiulis, Arunas, Ventura, Maria Teresa, Barbara, Cristina, Bergmann, Karl C., Bewick, Michael, Blain, Hubert, Bonini, Matteo, Boulet, Louis‐Philippe, Bourret, Rodolphe, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Cardona, Victoria, Casale, Thomas, Cecchi, Lorenzo, Charpin, Denis, Cherrez‐Ojeda, Ivan, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., Devillier, Philippe, Dramburg, Stephanie, Fokkens, Wytske J., Gotua, Maia, Heffler, Enrico, Ispayeva, Zhanat, Ivancevich, Juan Carlos, Joos, Guy, Kaidashev, Igor, Kraxner, Helga, Kvedariene, Violeta, Larenas‐Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga, Louis, Renaud, Makela, Mika, Makris, Michael, Maurer, Marcus, Melén, Erik, Micheli, Yann, Morais‐Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, O’Hehir, Robyn, Okamoto, Yoshitaka, Olze, Heidi, Papadopoulos, Nikolaos G., Papi, Alberto, Patella, Vincenzo, Pétré, Benoit, Pham‐Thi, Nhân, Puggioni, Francesca, Quirce, Santiago, Roche, Nicolas, Rouadi, Philip W., Sá‐Sousa, Ana, Sagara, Hironori, Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sova, Milan, Ulrik, Charlotte Suppli, Taborda‐Barata, Luis, Todo‐Bom, Ana, Torres, Maria J., Tsiligianni, Ioanna, Usmani, Omar S., Valovirta, Erkka, Vasankari, Tuula, Vieira, Rafael José, Wallace, Dana, Waserman, Susan, Zidarn, Mihaela, Yorgancioglu, Arzu, Zhang, Luo, Chivato, Tomas, and Ollert, Markus
Abstract: Biomarkers for the diagnosis, treatment and follow-up of patients with rhinitis and/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including mHealth) places the patient at the centre of the health system and is likely to optimise the practice of allergy. ARIA (Allergic Rhinitis and its Impact on Asthma) and EAACI (European Academy of Allergy and Clinical Immunology) developed a Task Force aimed at proposing patient-reported outcome measures (PROMs) as digital biomarkers that can be easily used for different purposes in rhinitis and asthma. It first defined control digital biomarkers that should make a bridge between clinical practice, randomised controlled trials, observational real-life studies and allergen challenges. Using the MASK-air app as a model, a daily electronic combined symptom-medication score for allergic diseases (CSMS) or for asthma (e-DASTHMA), combined with a monthly control questionnaire, were embedded in a strategy similar to the diabetes approach for disease control. To mimic real-life, it secondly proposed quality-of-life digital biomarkers including daily EQ-5D visual analogue scales and the bi-weekly RhinAsthma Patient Perspective (RAAP). The potential implications for the management of allergic respiratory diseases were proposed.
Published: 2023
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3. Consistent trajectories of rhinitis control and treatment in 16,177 weeks: The MASK-air (R) longitudinal study

Author: Sousa-Pinto, Bernardo, Schunemann, Holger J., Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Anto, Josep M., Klimek, Ludger, Czarlewski, Wienczyslawa, Mullol, Joaquim, Pfaar, Oliver, Bedbrook, Anna, Brussino, Luisa, Kvedariene, Violeta, Larenas-Linnemann, Desiree E., Okamoto, Yoshitaka, Ventura, Maria Teresa, Agache, Ioana, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Canonica, G. Walter, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Thomas, Cecchi, Lorenzo, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., Del Giacco, Stefano, Devillier, Philippe, Eklund, Patrik, Fokkens, Wytske J., Gemicioglu, Bilun, Haahtela, Tari, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Jutel, Marek, Kuna, Piotr, Kaidashev, Igor, Khaitov, Musa, Kraxner, Helga, Laune, Daniel, Lipworth, Brian, Louis, Renaud, Makris, Michael, Monti, Riccardo, Morais-Almeida, Mario, Mosges, Ralph, Niedoszytko, Marek, Papadopoulos, Nikolaos G., Patella, Vincenzo, Regateiro, Frederico S., Reitsma, Sietze, Rouadi, Philip W., Samolinski, Boleslaw, Sheikh, Aziz, Sova, Milan, Todo-Bom, Ana, Taborda-Barata, Luis, Toppila-Salmi, Sanna, Sastre, Joaquin, Tsiligianni, Ioanna, Valiulis, Arunas, Vandenplas, Olivier, Wallace, Dana, Waserman, Susan, Yorgancioglu, Arzu, Zidarn, Mihaela, Zuberbier, Torsten, Fonseca, Joao A., Bousquet, Jean, Sousa-Pinto, Bernardo, Schunemann, Holger J., Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Anto, Josep M., Klimek, Ludger, Czarlewski, Wienczyslawa, Mullol, Joaquim, Pfaar, Oliver, Bedbrook, Anna, Brussino, Luisa, Kvedariene, Violeta, Larenas-Linnemann, Desiree E., Okamoto, Yoshitaka, Ventura, Maria Teresa, Agache, Ioana, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Canonica, G. Walter, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Thomas, Cecchi, Lorenzo, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., Del Giacco, Stefano, Devillier, Philippe, Eklund, Patrik, Fokkens, Wytske J., Gemicioglu, Bilun, Haahtela, Tari, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Jutel, Marek, Kuna, Piotr, Kaidashev, Igor, Khaitov, Musa, Kraxner, Helga, Laune, Daniel, Lipworth, Brian, Louis, Renaud, Makris, Michael, Monti, Riccardo, Morais-Almeida, Mario, Mosges, Ralph, Niedoszytko, Marek, Papadopoulos, Nikolaos G., Patella, Vincenzo, Regateiro, Frederico S., Reitsma, Sietze, Rouadi, Philip W., Samolinski, Boleslaw, Sheikh, Aziz, Sova, Milan, Todo-Bom, Ana, Taborda-Barata, Luis, Toppila-Salmi, Sanna, Sastre, Joaquin, Tsiligianni, Ioanna, Valiulis, Arunas, Vandenplas, Olivier, Wallace, Dana, Waserman, Susan, Yorgancioglu, Arzu, Zidarn, Mihaela, Zuberbier, Torsten, Fonseca, Joao A., and Bousquet, Jean
Abstract: Introduction: Data from mHealth apps can provide valuable information on rhinitis control and treatment patterns. However, in MASK-air (R), these data have only been analyzed cross-sectionally, without considering the changes of symptoms over time. We analyzed data from MASK-air (R) longitudinally, clustering weeks according to reported rhinitis symptoms. Methods: We analyzed MASK-air (R) data, assessing the weeks for which patients had answered a rhinitis daily questionnaire on all 7days. We firstly used k-means clustering algorithms for longitudinal data to define clusters of weeks according to the trajectories of reported daily rhinitis symptoms. Clustering was applied separately for weeks when medication was reported or not. We compared obtained clusters on symptoms and rhinitis medication patterns. We then used the latent class mixture model to assess the robustness of results. Results: We analyzed 113,239 days (16,177 complete weeks) from 2590 patients (mean age +/- SD = 39.1 +/- 13.7 years). The first clustering algorithm identified ten clusters among weeks with medication use: seven with low variability in rhinitis control during the week and three with highly-variable control. Clusters with poorly-controlled rhinitis displayed a higher frequency of rhinitis co-medication, a more frequent change of medication schemes and more pronounced seasonal patterns. Six clusters were identified in weeks when no rhinitis medication was used, displaying similar control patterns. The second clustering method provided similar results. Moreover, patients displayed consistent levels of rhinitis control, reporting several weeks with similar levels of control. Conclusions: We identified 16 patterns of weekly rhinitis control. Co-medication and medication change schemes were common in uncontrolled weeks, reinforcing the hypothesis that patients treat themselves according to their symptoms. [GRAPHICS] .
Published: 2023

4. Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: The ARIA‐MASK‐air ® approach

Author: Bousquet, Jean, Anto, Josep M., Sousa‐Pinto, Bernardo, Czarlewski, Wienczyslawa, Bedbrook, Anna, Haahtela, Tari, Klimek, Ludger, Pfaar, Oliver, Kuna, Piotr, Kupczyk, Maciej, Regateiro, Frederico S., Samolinski, Boleslaw, Valiulis, Arunas, Yorgancioglu, Arzu, Arnavielhe, Sylvie, Basagaña, Xavier, Bergmann, Karl C., Bosnic‐Anticevich, Sinthia, Brussino, Luisa, Canonica, G. Walter, Cardona, Victoria, Cecchi, Lorenzo, Chaves‐Loureiro, Claudia, Costa, Elisio, Cruz, Alvaro A., Gemicioglu, Bilun, Fokkens, Wytske J., Ivancevich, Juan Carlos, Kraxner, Helga, Kvedariene, Violeta, Larenas‐Linnemann, Désirée E., Laune, Daniel, Louis, Renaud, Makris, Michael, Maurer, Marcus, Melén, Erik, Micheli, Yann, Morais‐Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, Okamoto, Yoshitaka, Papadopoulos, Nikolaos G., Patella, Vincenzo, Pham‐Thi, Nhân, Rouadi, Philip W., Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sofiev, Mikhail, Taborda‐Barata, Luis, Toppila‐Salmi, Sanna, Tsiligianni, Ioanna, Valovirta, Erkka, Ventura, Maria Teresa, Vieira, Rafael José, Zidarn, Mihaela, Amaral, Rita, Ansotegui, Ignacio J., Bédard, Annabelle, Benveniste, Samuel, Bewick, Michael, Bindslev‐Jensen, Carsten, Blain, Hubert, Bonini, Matteo, Bourret, Rodolphe, Braido, Fulvio, Carreiro‐Martins, Pedro, Charpin, Denis, Cherrez‐Ojeda, Ivan, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Del Giacco, Stefano, de Blay, Frédéric, Devillier, Philippe, De Vries, Govert, Doulaptsi, Maria, Doyen, Virginie, Dray, Gérard, Fontaine, Jean‐François, Gomez, R. Maximiliano, Hagemann, Jan, Heffler, Enrico, Hofmann, Maja, Jassem, Ewa, Jutel, Marek, Keil, Thomas, Kritikos, Vicky, Kull, Inger, Kulus, Marek, Lourenço, Olga, Mathieu‐Dupas, Eve, Menditto, Enrica, Mösges, Ralph, Murray, Ruth, Nadif, Rachel, Neffen, Hugo, Nicola, Stefania, O’Hehir, Robyn, Olze, Heidi, Palamarchuk, Yuliia, Pépin, Jean‐Louis, Pétré, Benoit, Picard, Robert, Pitsios, Constantinos, Puggioni, Francesca, Quirce, Santiago, Raciborski, Filip, Reitsma, Sietze, Roche, Nicolas, Rodriguez‐Gonzalez, Monica, Romantowski, Jan, Sá‐Sousa, Ana, Serpa, Faradiba S., Savouré, Marine, Shamji, Mohamed H., Sova, Milan, Sperl, Annette, Stellato, Cristiana, Todo‐Bom, Ana, Tomazic, Peter Valentin, Vandenplas, Olivier, Van Eerd, Michiel, Vasankari, Tuula, Viart, Frédéric, Waserman, Susan, Fonseca, Joao A., Zuberbier, Torsten, Bousquet, Jean, Anto, Josep M., Sousa‐Pinto, Bernardo, Czarlewski, Wienczyslawa, Bedbrook, Anna, Haahtela, Tari, Klimek, Ludger, Pfaar, Oliver, Kuna, Piotr, Kupczyk, Maciej, Regateiro, Frederico S., Samolinski, Boleslaw, Valiulis, Arunas, Yorgancioglu, Arzu, Arnavielhe, Sylvie, Basagaña, Xavier, Bergmann, Karl C., Bosnic‐Anticevich, Sinthia, Brussino, Luisa, Canonica, G. Walter, Cardona, Victoria, Cecchi, Lorenzo, Chaves‐Loureiro, Claudia, Costa, Elisio, Cruz, Alvaro A., Gemicioglu, Bilun, Fokkens, Wytske J., Ivancevich, Juan Carlos, Kraxner, Helga, Kvedariene, Violeta, Larenas‐Linnemann, Désirée E., Laune, Daniel, Louis, Renaud, Makris, Michael, Maurer, Marcus, Melén, Erik, Micheli, Yann, Morais‐Almeida, Mario, Mullol, Joaquim, Niedoszytko, Marek, Okamoto, Yoshitaka, Papadopoulos, Nikolaos G., Patella, Vincenzo, Pham‐Thi, Nhân, Rouadi, Philip W., Sastre, Joaquin, Scichilone, Nicola, Sheikh, Aziz, Sofiev, Mikhail, Taborda‐Barata, Luis, Toppila‐Salmi, Sanna, Tsiligianni, Ioanna, Valovirta, Erkka, Ventura, Maria Teresa, Vieira, Rafael José, Zidarn, Mihaela, Amaral, Rita, Ansotegui, Ignacio J., Bédard, Annabelle, Benveniste, Samuel, Bewick, Michael, Bindslev‐Jensen, Carsten, Blain, Hubert, Bonini, Matteo, Bourret, Rodolphe, Braido, Fulvio, Carreiro‐Martins, Pedro, Charpin, Denis, Cherrez‐Ojeda, Ivan, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Del Giacco, Stefano, de Blay, Frédéric, Devillier, Philippe, De Vries, Govert, Doulaptsi, Maria, Doyen, Virginie, Dray, Gérard, Fontaine, Jean‐François, Gomez, R. Maximiliano, Hagemann, Jan, Heffler, Enrico, Hofmann, Maja, Jassem, Ewa, Jutel, Marek, Keil, Thomas, Kritikos, Vicky, Kull, Inger, Kulus, Marek, Lourenço, Olga, Mathieu‐Dupas, Eve, Menditto, Enrica, Mösges, Ralph, Murray, Ruth, Nadif, Rachel, Neffen, Hugo, Nicola, Stefania, O’Hehir, Robyn, Olze, Heidi, Palamarchuk, Yuliia, Pépin, Jean‐Louis, Pétré, Benoit, Picard, Robert, Pitsios, Constantinos, Puggioni, Francesca, Quirce, Santiago, Raciborski, Filip, Reitsma, Sietze, Roche, Nicolas, Rodriguez‐Gonzalez, Monica, Romantowski, Jan, Sá‐Sousa, Ana, Serpa, Faradiba S., Savouré, Marine, Shamji, Mohamed H., Sova, Milan, Sperl, Annette, Stellato, Cristiana, Todo‐Bom, Ana, Tomazic, Peter Valentin, Vandenplas, Olivier, Van Eerd, Michiel, Vasankari, Tuula, Viart, Frédéric, Waserman, Susan, Fonseca, Joao A., and Zuberbier, Torsten
Abstract: MASK‐air®, a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK‐air® is a Good Practice of DG Santé on digitally‐enabled, patient‐centred care. It is also a candidate Good Practice of OECD (Organisation for Economic Co‐operation and Development). MASK‐air® data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK‐air® data show that most rhinitis patients (i) are not adherent and do not follow guidelines, (ii) use as‐needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recommended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom‐medication score (ARIA‐EAACI‐CSMS) has been validated for clinical practice and trials. The implications of the novel MASK‐air® results should lead to change management in rhinitis and asthma.
Published: 2023

5. Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The ARIA‐EAACI approach – ARIA‐EAACI Task Force Report

Author: Bousquet, Jean, primary, Shamji, Mohamed H., additional, Anto, Josep M., additional, Schünemann, Holger J., additional, Canonica, G. Walter, additional, Jutel, Marek, additional, Del Giacco, Stefano, additional, Zuberbier, Torsten, additional, Pfaar, Oliver, additional, Fonseca, Joao A., additional, Sousa‐Pinto, Bernardo, additional, Klimek, Ludger, additional, Czarlewski, Wienczyslawa, additional, Bedbrook, Anna, additional, Amaral, Rita, additional, Ansotegui, Ignacio J., additional, Bosnic‐Anticevich, Sinthia, additional, Braido, Fulvio, additional, Chaves Loureiro, Claudia, additional, Gemicioglu, Bilun, additional, Haahtela, Tari, additional, Kulus, Marek, additional, Kuna, Piotr, additional, Kupczyk, Maciej, additional, Matricardi, Paolo M., additional, Regateiro, Frederico S., additional, Samolinski, Boleslaw, additional, Sofiev, Mikhail, additional, Toppila‐Salmi, Sanna, additional, Valiulis, Arunas, additional, Ventura, Maria Teresa, additional, Barbara, Cristina, additional, Bergmann, Karl C., additional, Bewick, Michael, additional, Blain, Hubert, additional, Bonini, Matteo, additional, Boulet, Louis‐Philippe, additional, Bourret, Rodolphe, additional, Brusselle, Guy, additional, Brussino, Luisa, additional, Buhl, Roland, additional, Cardona, Victoria, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Charpin, Denis, additional, Cherrez‐Ojeda, Ivan, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Costa, Elisio M., additional, Cruz, Alvaro A., additional, Devillier, Philippe, additional, Dramburg, Stephanie, additional, Fokkens, Wytske J., additional, Gotua, Maia, additional, Heffler, Enrico, additional, Ispayeva, Zhanat, additional, Ivancevich, Juan Carlos, additional, Joos, Guy, additional, Kaidashev, Igor, additional, Kraxner, Helga, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Désirée E., additional, Laune, Daniel, additional, Lourenço, Olga, additional, Louis, Renaud, additional, Makela, Mika, additional, Makris, Michael, additional, Maurer, Marcus, additional, Melén, Erik, additional, Micheli, Yann, additional, Morais‐Almeida, Mario, additional, Mullol, Joaquim, additional, Niedoszytko, Marek, additional, O'Hehir, Robyn, additional, Okamoto, Yoshitaka, additional, Olze, Heidi, additional, Papadopoulos, Nikolaos G., additional, Papi, Alberto, additional, Patella, Vincenzo, additional, Pétré, Benoit, additional, Pham‐Thi, Nhân, additional, Puggioni, Francesca, additional, Quirce, Santiago, additional, Roche, Nicolas, additional, Rouadi, Philip W., additional, Sá‐Sousa, Ana, additional, Sagara, Hironori, additional, Sastre, Joaquin, additional, Scichilone, Nicola, additional, Sheikh, Aziz, additional, Sova, Milan, additional, Suppli Ulrik, Charlotte, additional, Taborda‐Barata, Luis, additional, Todo‐Bom, Ana, additional, Torres, Maria J., additional, Tsiligianni, Ioanna, additional, Usmani, Omar S., additional, Valovirta, Erkka, additional, Vasankari, Tuula, additional, Vieira, Rafael José, additional, Wallace, Dana, additional, Waserman, Susan, additional, Zidarn, Mihaela, additional, Yorgancioglu, Arzu, additional, Zhang, Luo, additional, Chivato, Tomas, additional, and Ollert, Markus, additional
Published: 2023
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6. Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: The ARIA‐MASK‐air ® approach

Author: Bousquet, Jean, primary, Anto, Josep M., additional, Sousa‐Pinto, Bernardo, additional, Czarlewski, Wienczyslawa, additional, Bedbrook, Anna, additional, Haahtela, Tari, additional, Klimek, Ludger, additional, Pfaar, Oliver, additional, Kuna, Piotr, additional, Kupczyk, Maciej, additional, Regateiro, Frederico S., additional, Samolinski, Boleslaw, additional, Valiulis, Arunas, additional, Yorgancioglu, Arzu, additional, Arnavielhe, Sylvie, additional, Basagaña, Xavier, additional, Bergmann, Karl C., additional, Bosnic‐Anticevich, Sinthia, additional, Brussino, Luisa, additional, Canonica, G. Walter, additional, Cardona, Victoria, additional, Cecchi, Lorenzo, additional, Chaves‐Loureiro, Claudia, additional, Costa, Elisio, additional, Cruz, Alvaro A., additional, Gemicioglu, Bilun, additional, Fokkens, Wytske J., additional, Ivancevich, Juan Carlos, additional, Kraxner, Helga, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Désirée E., additional, Laune, Daniel, additional, Louis, Renaud, additional, Makris, Michael, additional, Maurer, Marcus, additional, Melén, Erik, additional, Micheli, Yann, additional, Morais‐Almeida, Mario, additional, Mullol, Joaquim, additional, Niedoszytko, Marek, additional, Okamoto, Yoshitaka, additional, Papadopoulos, Nikolaos G., additional, Patella, Vincenzo, additional, Pham‐Thi, Nhân, additional, Rouadi, Philip W., additional, Sastre, Joaquin, additional, Scichilone, Nicola, additional, Sheikh, Aziz, additional, Sofiev, Mikhail, additional, Taborda‐Barata, Luis, additional, Toppila‐Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Valovirta, Erkka, additional, Ventura, Maria Teresa, additional, Vieira, Rafael José, additional, Zidarn, Mihaela, additional, Amaral, Rita, additional, Ansotegui, Ignacio J., additional, Bédard, Annabelle, additional, Benveniste, Samuel, additional, Bewick, Michael, additional, Bindslev‐Jensen, Carsten, additional, Blain, Hubert, additional, Bonini, Matteo, additional, Bourret, Rodolphe, additional, Braido, Fulvio, additional, Carreiro‐Martins, Pedro, additional, Charpin, Denis, additional, Cherrez‐Ojeda, Ivan, additional, Chivato, Tomas, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Del Giacco, Stefano, additional, de Blay, Frédéric, additional, Devillier, Philippe, additional, De Vries, Govert, additional, Doulaptsi, Maria, additional, Doyen, Virginie, additional, Dray, Gérard, additional, Fontaine, Jean‐François, additional, Gomez, R. Maximiliano, additional, Hagemann, Jan, additional, Heffler, Enrico, additional, Hofmann, Maja, additional, Jassem, Ewa, additional, Jutel, Marek, additional, Keil, Thomas, additional, Kritikos, Vicky, additional, Kull, Inger, additional, Kulus, Marek, additional, Lourenço, Olga, additional, Mathieu‐Dupas, Eve, additional, Menditto, Enrica, additional, Mösges, Ralph, additional, Murray, Ruth, additional, Nadif, Rachel, additional, Neffen, Hugo, additional, Nicola, Stefania, additional, O’Hehir, Robyn, additional, Olze, Heidi, additional, Palamarchuk, Yuliia, additional, Pépin, Jean‐Louis, additional, Pétré, Benoit, additional, Picard, Robert, additional, Pitsios, Constantinos, additional, Puggioni, Francesca, additional, Quirce, Santiago, additional, Raciborski, Filip, additional, Reitsma, Sietze, additional, Roche, Nicolas, additional, Rodriguez‐Gonzalez, Monica, additional, Romantowski, Jan, additional, Sá‐Sousa, Ana, additional, Serpa, Faradiba S., additional, Savouré, Marine, additional, Shamji, Mohamed H., additional, Sova, Milan, additional, Sperl, Annette, additional, Stellato, Cristiana, additional, Todo‐Bom, Ana, additional, Tomazic, Peter Valentin, additional, Vandenplas, Olivier, additional, Van Eerd, Michiel, additional, Vasankari, Tuula, additional, Viart, Frédéric, additional, Waserman, Susan, additional, Fonseca, Joao A., additional, and Zuberbier, Torsten, additional
Published: 2023
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7. Consistent trajectories of rhinitis control and treatment in 16,177 weeks: The MASK‐air® longitudinal study

Author: Sousa‐Pinto, Bernardo, primary, Schünemann, Holger J., additional, Sá‐Sousa, Ana, additional, Vieira, Rafael José, additional, Amaral, Rita, additional, Anto, Josep M., additional, Klimek, Ludger, additional, Czarlewski, Wienczyslawa, additional, Mullol, Joaquim, additional, Pfaar, Oliver, additional, Bedbrook, Anna, additional, Brussino, Luisa, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Désirée E., additional, Okamoto, Yoshitaka, additional, Ventura, Maria Teresa, additional, Agache, Ioana, additional, Ansotegui, Ignacio J., additional, Bergmann, Karl C., additional, Bosnic‐Anticevich, Sinthia, additional, Canonica, G. Walter, additional, Cardona, Victoria, additional, Carreiro‐Martins, Pedro, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Chivato, Tomas, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Costa, Elísio M., additional, Cruz, Alvaro A., additional, Del Giacco, Stefano, additional, Devillier, Philippe, additional, Eklund, Patrik, additional, Fokkens, Wytske J., additional, Gemicioglu, Bilun, additional, Haahtela, Tari, additional, Ivancevich, Juan Carlos, additional, Ispayeva, Zhanat, additional, Jutel, Marek, additional, Kuna, Piotr, additional, Kaidashev, Igor, additional, Khaitov, Musa, additional, Kraxner, Helga, additional, Laune, Daniel, additional, Lipworth, Brian, additional, Louis, Renaud, additional, Makris, Michael, additional, Monti, Riccardo, additional, Morais‐Almeida, Mario, additional, Mösges, Ralph, additional, Niedoszytko, Marek, additional, Papadopoulos, Nikolaos G., additional, Patella, Vincenzo, additional, Pham‐Thi, Nhân, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Rouadi, Philip W., additional, Samolinski, Boleslaw, additional, Sheikh, Aziz, additional, Sova, Milan, additional, Todo‐Bom, Ana, additional, Taborda‐Barata, Luis, additional, Toppila‐Salmi, Sanna, additional, Sastre, Joaquin, additional, Tsiligianni, Ioanna, additional, Valiulis, Arunas, additional, Vandenplas, Olivier, additional, Wallace, Dana, additional, Waserman, Susan, additional, Yorgancioglu, Arzu, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, Fonseca, Joao A., additional, and Bousquet, Jean, additional
Published: 2022
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8. Real‐world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities

Author: Sousa‐Pinto, Bernardo, primary, Anto, Aram, additional, Berger, Markus, additional, Dramburg, Stephanie, additional, Pfaar, Oliver, additional, Klimek, Ludger, additional, Jutel, Marek, additional, Czarlewski, Wienczyslawa, additional, Bedbrook, Anna, additional, Valiulis, Arunas, additional, Agache, Ioana, additional, Amaral, Rita, additional, Ansotegui, Ignacio J., additional, Bastl, Katharina, additional, Berger, Uwe, additional, Bergmann, Karl C., additional, Bosnic‐Anticevich, Sinthia, additional, Braido, Fulvio, additional, Brussino, Luisa, additional, Cardona, Victoria, additional, Casale, Thomas, additional, Canonica, G. Walter, additional, Cecchi, Lorenzo, additional, Charpin, Denis, additional, Chivato, Tomás, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Costa, Elisio M., additional, Cruz, Alvaro A., additional, Devillier, Philippe, additional, Durham, Stephen R., additional, Ebisawa, Motohiro, additional, Fiocchi, Alessandro, additional, Fokkens, Wytske J., additional, Gemicioğlu, Bilun, additional, Gotua, Maia, additional, Guzmán, Maria‐Antonieta, additional, Haahtela, Tari, additional, Ivancevich, Juan Carlos, additional, Kuna, Piotr, additional, Kaidashev, Igor, additional, Khaitov, Musa, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Désirée E., additional, Lipworth, Brian, additional, Laune, Daniel, additional, Matricardi, Paolo M., additional, Morais‐Almeida, Mario, additional, Mullol, Joaquim, additional, Naclerio, Robert, additional, Neffen, Hugo, additional, Nekam, Kristoff, additional, Niedoszytko, Marek, additional, Okamoto, Yoshitaka, additional, Papadopoulos, Nikolaos G., additional, Park, Hae‐Sim, additional, Passalacqua, Giovanni, additional, Patella, Vincenzo, additional, Pelosi, Simone, additional, Pham‐Thi, Nhân, additional, Popov, Ted A., additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Rodriguez‐Gonzales, Monica, additional, Rosario, Nelson, additional, Rouadi, Philip W., additional, Samolinski, Boleslaw, additional, Sá‐Sousa, Ana, additional, Sastre, Joaquin, additional, Sheikh, Aziz, additional, Ulrik, Charlotte Suppli, additional, Taborda‐Barata, Luis, additional, Todo‐Bom, Ana, additional, Tomazic, Peter Valentin, additional, Toppila‐Salmi, Sanna, additional, Tripodi, Salvatore, additional, Tsiligianni, Ioanna, additional, Valovirta, Erkka, additional, Ventura, Maria Teresa, additional, Valero, Antonio A., additional, Vieira, Rafael José, additional, Wallace, Dana, additional, Waserman, Susan, additional, Williams, Sian, additional, Yorgancioglu, Arzu, additional, Zhang, Luo, additional, Zidarn, Mihaela, additional, Zuberbier, Jaron, additional, Olze, Heidi, additional, Antó, Josep M., additional, Zuberbier, Torsten, additional, Fonseca, João A., additional, and Bousquet, Jean, additional
Published: 2022
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9. Allergies and COVID-19 vaccines : An ENDA/EAACI Position paper

Author: Barbaud, Annick, Garvey, Lene Heise, Arcolaci, Alessandra, Brockow, Knut, Mori, Francesca, Mayorga, Cristobalina, Bonadonna, Patrizia, Atanaskovic-Markovic, Marina, Moral, Luis, Zanoni, Giovanna, Pagani, Mauro, Soria, Angele, Jost, Maja, Caubet, Jean-Christoph, Carmo, Abreu, Mona, Al-Ahmad, Alvarez-Perea, Alberto, Bavbek, Sevim, Benedetta, Biagioni, Bilo, M. Beatrice, Blanca-Lopez, Natalia, Bogas, Herrera Gador, Buonomo, Alessandro, Calogiuri, Gianfranco, Carli, Giulia, Cernadas, Josefina, Cortellini, Gabriele, Celik, Gulfem, Demir, Semra, Dona, Inmaculada, Dursun, Adile Berna, Eberlein, Bernadette, Faria, Emilia, Fernandes, Bryan, Garcez, Tomaz, Garcia-Nunez, Ignacio, Gawlik, Radoslaw, Gelincik, Asli, Gomes, Eva, Gooi, Jimmy H. C., Grosber, Martine, Gulen, Theo, Hacard, Florence, Hoarau, Cyrille, Janson, Christer, Johnston, Sebastian L., Joerg, Lukas, Ozdemir, Secil Kepil, Klimek, Ludger, Kosnik, Mitja, Kowalski, Marek L., Kuyucu, Semanur, Kvedariene, Violeta, Laguna, Jose Julio, Lombardo, Carla, Marinho, Susana, Merk, Hans, Meucci, Elisa, Morisset, Martine, Munoz-Cano, Rosa, Murzilli, Francesco, Nakonechna, Alla, Popescu, Florin-Dan, Porebski, Grzegorz, Radice, Anna, Regateiro, Frederico S., Rockmann, Heike, Romano, Antonino, Sargur, Ravishankar, Sastre, Joaquin, Hofmeier, Kathrin Scherer, Sedlackova, Lenka, Sobotkova, Marta, Terreehorst, Ingrid, Treudler, Regina, Walusiak-Skorupa, Jolanta, Wedi, Bettina, Wohrl, Stefan, Zidarn, Mihael, Zuberbier, Torsten, Agache, Ioana, Torres, Maria J., Barbaud, Annick, Garvey, Lene Heise, Arcolaci, Alessandra, Brockow, Knut, Mori, Francesca, Mayorga, Cristobalina, Bonadonna, Patrizia, Atanaskovic-Markovic, Marina, Moral, Luis, Zanoni, Giovanna, Pagani, Mauro, Soria, Angele, Jost, Maja, Caubet, Jean-Christoph, Carmo, Abreu, Mona, Al-Ahmad, Alvarez-Perea, Alberto, Bavbek, Sevim, Benedetta, Biagioni, Bilo, M. Beatrice, Blanca-Lopez, Natalia, Bogas, Herrera Gador, Buonomo, Alessandro, Calogiuri, Gianfranco, Carli, Giulia, Cernadas, Josefina, Cortellini, Gabriele, Celik, Gulfem, Demir, Semra, Dona, Inmaculada, Dursun, Adile Berna, Eberlein, Bernadette, Faria, Emilia, Fernandes, Bryan, Garcez, Tomaz, Garcia-Nunez, Ignacio, Gawlik, Radoslaw, Gelincik, Asli, Gomes, Eva, Gooi, Jimmy H. C., Grosber, Martine, Gulen, Theo, Hacard, Florence, Hoarau, Cyrille, Janson, Christer, Johnston, Sebastian L., Joerg, Lukas, Ozdemir, Secil Kepil, Klimek, Ludger, Kosnik, Mitja, Kowalski, Marek L., Kuyucu, Semanur, Kvedariene, Violeta, Laguna, Jose Julio, Lombardo, Carla, Marinho, Susana, Merk, Hans, Meucci, Elisa, Morisset, Martine, Munoz-Cano, Rosa, Murzilli, Francesco, Nakonechna, Alla, Popescu, Florin-Dan, Porebski, Grzegorz, Radice, Anna, Regateiro, Frederico S., Rockmann, Heike, Romano, Antonino, Sargur, Ravishankar, Sastre, Joaquin, Hofmeier, Kathrin Scherer, Sedlackova, Lenka, Sobotkova, Marta, Terreehorst, Ingrid, Treudler, Regina, Walusiak-Skorupa, Jolanta, Wedi, Bettina, Wohrl, Stefan, Zidarn, Mihael, Zuberbier, Torsten, Agache, Ioana, and Torres, Maria J.
Abstract: Background Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management is not standardized. Method Members of the European Network for Drug Allergy and the European Academy of Allergy and Clinical Immunology interested in drug allergy participated in an online questionnaire on pre-vaccination screening and management of allergic reactions to COVID-19 vaccines, and literature was analysed. Results No death due to anaphylaxis to COVID-19 vaccines has been confirmed in scientific literature. Potential allergens, polyethylene glycol (PEG), polysorbate and tromethamine are excipients. The authors propose allergy evaluation of persons with the following histories: 1-anaphylaxis to injectable drug or vaccine containing PEG or derivatives; 2-anaphylaxis to oral/topical PEG containing products; 3-recurrent anaphylaxis of unknown cause; 4-suspected or confirmed allergy to any mRNA vaccine; and 5-confirmed allergy to PEG or derivatives. We recommend a prick-to-prick skin test with the left-over solution in the suspected vaccine vial to avoid waste. Prick test panel should include PEG 4000 or 3500, PEG 2000 and polysorbate 80. The value of in vitro test is arguable. Conclusions These recommendations will lead to a better knowledge of the management and mechanisms involved in anaphylaxis to COVID-19 vaccines and enable more people with history of allergy to be vaccinated.
Published: 2022
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10. Comparison of rhinitis treatments using MASK-air (R) data and considering the minimal important difference

Author: Sousa-Pinto, Bernardo, Schunemann, Holger J., Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Anto, Josep M., Klimek, Ludger, Czarlewski, Wienczyslawa, Mullol, Joaquim, Pfaar, Oliver, Bedbrook, Anna, Brussino, Luisa, Kvedariene, Violeta, Larenas-Linnemann, Desiree, Okamoto, Yoshitaka, Ventura, Maria Teresa, Agache, Ioana, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Brozek, Jan, Canonica, G. Walter, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Thomas, Cecchi, Lorenzo, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., Del Giacco, Stefano, Devillier, Philippe, Eklund, Patrik, Fokkens, Wytske J., Gemicioglu, Bilun, Haahtela, Tari, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Jutel, Marek, Kuna, Piotr, Kaidashev, Igor, Khaitov, Musa, Kraxner, Helga, Laune, Daniel, Lipworth, Brian, Louis, Renaud, Makris, Michael, Monti, Riccardo, Morais-Almeida, Mario, Moesges, Ralph, Niedoszytko, Marek, Papadopoulos, Nikolaos G., Patella, Vincenzo, Pham-Thi, Nhan, Regateiro, Frederico S., Reitsma, Sietze, Rouadi, Philip W., Samolinski, Boleslaw, Sheikh, Aziz, Sova, Milan, Todo-Bom, Ana, Taborda-Barata, Luis, Toppila-Salmi, Sanna, Sastre, Joaquin, Tsiligianni, Ioanna, Valiulis, Arunas, Vandenplas, Olivier, Wallace, Dana, Waserman, Susan, Yorgancioglu, Arzu, Zidarn, Mihaela, Zuberbier, Torsten, Fonseca, Joao A., Bousquet, Jean, Sousa-Pinto, Bernardo, Schunemann, Holger J., Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Anto, Josep M., Klimek, Ludger, Czarlewski, Wienczyslawa, Mullol, Joaquim, Pfaar, Oliver, Bedbrook, Anna, Brussino, Luisa, Kvedariene, Violeta, Larenas-Linnemann, Desiree, Okamoto, Yoshitaka, Ventura, Maria Teresa, Agache, Ioana, Ansotegui, Ignacio J., Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Brozek, Jan, Canonica, G. Walter, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Thomas, Cecchi, Lorenzo, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., Del Giacco, Stefano, Devillier, Philippe, Eklund, Patrik, Fokkens, Wytske J., Gemicioglu, Bilun, Haahtela, Tari, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Jutel, Marek, Kuna, Piotr, Kaidashev, Igor, Khaitov, Musa, Kraxner, Helga, Laune, Daniel, Lipworth, Brian, Louis, Renaud, Makris, Michael, Monti, Riccardo, Morais-Almeida, Mario, Moesges, Ralph, Niedoszytko, Marek, Papadopoulos, Nikolaos G., Patella, Vincenzo, Pham-Thi, Nhan, Regateiro, Frederico S., Reitsma, Sietze, Rouadi, Philip W., Samolinski, Boleslaw, Sheikh, Aziz, Sova, Milan, Todo-Bom, Ana, Taborda-Barata, Luis, Toppila-Salmi, Sanna, Sastre, Joaquin, Tsiligianni, Ioanna, Valiulis, Arunas, Vandenplas, Olivier, Wallace, Dana, Waserman, Susan, Yorgancioglu, Arzu, Zidarn, Mihaela, Zuberbier, Torsten, Fonseca, Joao A., and Bousquet, Jean
Abstract: Background Different treatments exist for allergic rhinitis (AR), including pharmacotherapy and allergen immunotherapy (AIT), but they have not been compared using direct patient data (i.e., real-world data). We aimed to compare AR pharmacological treatments on (i) daily symptoms, (ii) frequency of use in co-medication, (iii) visual analogue scales (VASs) on allergy symptom control considering the minimal important difference (MID) and (iv) the effect of AIT. Methods We assessed the MASK-air (R) app data (May 2015-December 2020) by users self-reporting AR (16-90 years). We compared eight AR medication schemes on reported VAS of allergy symptoms, clustering data by the patient and controlling for confounding factors. We compared (i) allergy symptoms between patients with and without AIT and (ii) different drug classes used in co-medication. Results We analysed 269,837 days from 10,860 users. Most days (52.7%) involved medication use. Median VAS levels were significantly higher in co-medication than in monotherapy (including the fixed combination azelastine-fluticasone) schemes. In adjusted models, azelastine-fluticasone was associated with lower average VAS global allergy symptoms than all other medication schemes, while the contrary was observed for oral corticosteroids. AIT was associated with a decrease in allergy symptoms in some medication schemes. A difference larger than the MID compared to no treatment was observed for oral steroids. Azelastine-fluticasone was the drug class with the lowest chance of being used in co-medication (adjusted OR = 0.75; 95% CI = 0.71-0.80). Conclusion Median VAS levels were higher in co-medication than in monotherapy. Patients with more severe symptoms report a higher treatment, which is currently not reflected in guidelines.
Published: 2022

11. Allergen immunotherapy in MASK-air users in real-life: Results of a Bayesian mixed-effects model

Author: Sousa-Pinto, Bernardo, Azevedo, Luis Filipe, Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Klimek, Ludger, Czarlewski, Wienczyslawa, Anto, Josep M., Bedbrook, Anna, Kvedariene, Violeta, Ventura, Maria Teresa, Ansotegui, Ignacio J., Bergmann, Karl-Christian, Brussino, Luisa, Canonica, G. Walter, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Thomas, Cecchi, Lorenzo, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., De Feo, Giulia, Devillier, Philippe, Fokkens, Wytske J., Gaga, Mina, Gemicioglu, Bilun, Haahtela, Tari, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Jutel, Marek, Kuna, Piotr, Kaidashev, Igor, Kraxner, Helga, Larenas-Linnemann, Desiree E., Laune, Daniel, Lipworth, Brian, Louis, Renaud, Makris, Michael, Monti, Riccardo, Morais-Almeida, Mario, Moesges, Ralph, Mullol, Joaquim, Odemyr, Mikaela, Okamoto, Yoshitaka, Papadopoulos, Nikolaos G., Patella, Vincenzo, Regateiro, Frederico S., Reitsma, Sietze, Rouadi, Philip W., Samolinski, Boleslaw, Sova, Milan, Todo-Bom, Ana, Taborda-Barata, Luis, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Sastre, Joaquin, Tsiligianni, Ioanna, Valiulis, Arunas, Wallace, Dana, Waserman, Susan, Yorgancioglu, Arzu, Zidarn, Mihaela, Zuberbier, Torsten, Fonseca, Joao Almeida, Bousquet, Jean, Pfaar, Oliver, Sousa-Pinto, Bernardo, Azevedo, Luis Filipe, Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Klimek, Ludger, Czarlewski, Wienczyslawa, Anto, Josep M., Bedbrook, Anna, Kvedariene, Violeta, Ventura, Maria Teresa, Ansotegui, Ignacio J., Bergmann, Karl-Christian, Brussino, Luisa, Canonica, G. Walter, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Thomas, Cecchi, Lorenzo, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., De Feo, Giulia, Devillier, Philippe, Fokkens, Wytske J., Gaga, Mina, Gemicioglu, Bilun, Haahtela, Tari, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Jutel, Marek, Kuna, Piotr, Kaidashev, Igor, Kraxner, Helga, Larenas-Linnemann, Desiree E., Laune, Daniel, Lipworth, Brian, Louis, Renaud, Makris, Michael, Monti, Riccardo, Morais-Almeida, Mario, Moesges, Ralph, Mullol, Joaquim, Odemyr, Mikaela, Okamoto, Yoshitaka, Papadopoulos, Nikolaos G., Patella, Vincenzo, Regateiro, Frederico S., Reitsma, Sietze, Rouadi, Philip W., Samolinski, Boleslaw, Sova, Milan, Todo-Bom, Ana, Taborda-Barata, Luis, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Sastre, Joaquin, Tsiligianni, Ioanna, Valiulis, Arunas, Wallace, Dana, Waserman, Susan, Yorgancioglu, Arzu, Zidarn, Mihaela, Zuberbier, Torsten, Fonseca, Joao Almeida, Bousquet, Jean, and Pfaar, Oliver
Abstract: Background Evidence regarding the effectiveness of allergen immunotherapy (AIT) on allergic rhinitis has been provided mostly by randomised controlled trials, with little data from real-life studies. Objective To compare the reported control of allergic rhinitis symptoms in three groups of users of the MASK-air(R) app: those receiving sublingual AIT (SLIT), those receiving subcutaneous AIT (SCIT), and those receiving no AIT. Methods We assessed the MASK-air(R) data of European users with self-reported grass pollen allergy, comparing the data reported by patients receiving SLIT, SCIT and no AIT. Outcome variables included the daily impact of allergy symptoms globally and on work (measured by visual analogue scales-VASs), and a combined symptom-medication score (CSMS). We applied Bayesian mixed-effects models, with clustering by patient, country and pollen season. Results We analysed a total of 42,756 days from 1,093 grass allergy patients, including 18,479 days of users under AIT. Compared to no AIT, SCIT was associated with similar VAS levels and CSMS. Compared to no AIT, SLIT-tablet was associated with lower values of VAS global allergy symptoms (average difference = 7.5 units out of 100; 95% credible interval [95%CrI] = -12.1;-2.8), lower VAS Work (average difference = 5.0; 95%CrI = -8.5;-1.5), and a lower CSMS (average difference = 3.7; 95%CrI = -9.3;2.2). When compared to SCIT, SLIT-tablet was associated with lower VAS global allergy symptoms (average difference = 10.2; 95%CrI = -17.2;-2.8), lower VAS Work (average difference = 7.8; 95%CrI = -15.1;0.2), and a lower CSMS (average difference = 9.3; 95%CrI = -18.5;0.2). Conclusion In patients with grass pollen allergy, SLIT-tablet, when compared to no AIT and to SCIT, is associated with lower reported symptom severity. Future longitudinal studies following internationally-harmonised standards for performing and reporting real-world data in AIT are needed to better understand its 'real-world' effectiveness.
Published: 2022

12. Behavioural patterns in allergic rhinitis medication in Europe: A study using MASK-air(R) real-world data

Author: Sousa-Pinto, Bernardo, Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Klimek, Ludger, Czarlewski, Wienczyslawa, Anto, Josep M., Pfaar, Oliver, Bedbrook, Anna, Kvedariene, Violeta, Ventura, Maria Teresa, Ansotegui, Ignacio J., Bergmann, Karl-Christian, Brussino, Luisa, Canonica, G. Walter, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Tomas, Cecchi, Lorenzo, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., De Feo, Giulia, Devillier, Philippe, Fokkens, Wytske J., Gaga, Mina, Gemicioglu, Bilun, Haahtela, Tari, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Jutel, Marek, Kuna, Piotr, Kaidashev, Igor, Kraxner, Helga, Larenas-Linnemann, Desiree E., Laune, Daniel, Lipworth, Brian, Louis, Renaud, Makris, Michael, Monti, Riccardo, Morais-Almeida, Mario, Mosges, Ralph, Mullol, Joaquim, Odemyr, Mikaela, Okamoto, Yoshitaka, Papadopoulos, Nikolaos G., Patella, Vincenzo, Pham-Thi, Nhan, Regateiro, Frederico S., Reitsma, Sietze, Rouadi, Philip W., Samolinski, Boleslaw, Sova, Milan, Todo-Bom, Ana, Taborda-Barata, Luis, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Sastre, Joaquin, Tsiligianni, Ioanna, Valiulis, Arunas, Vandenplas, Olivier, Wallace, Dana, Waserman, Susan, Yorgancioglu, Arzu, Zidarn, Mihaela, Zuberbier, Torsten, Fonseca, Joao A., Bousquet, Jean, Sousa-Pinto, Bernardo, Sa-Sousa, Ana, Vieira, Rafael Jose, Amaral, Rita, Klimek, Ludger, Czarlewski, Wienczyslawa, Anto, Josep M., Pfaar, Oliver, Bedbrook, Anna, Kvedariene, Violeta, Ventura, Maria Teresa, Ansotegui, Ignacio J., Bergmann, Karl-Christian, Brussino, Luisa, Canonica, G. Walter, Cardona, Victoria, Carreiro-Martins, Pedro, Casale, Tomas, Cecchi, Lorenzo, Chivato, Tomas, Chu, Derek K., Cingi, Cemal, Costa, Elisio M., Cruz, Alvaro A., De Feo, Giulia, Devillier, Philippe, Fokkens, Wytske J., Gaga, Mina, Gemicioglu, Bilun, Haahtela, Tari, Ivancevich, Juan Carlos, Ispayeva, Zhanat, Jutel, Marek, Kuna, Piotr, Kaidashev, Igor, Kraxner, Helga, Larenas-Linnemann, Desiree E., Laune, Daniel, Lipworth, Brian, Louis, Renaud, Makris, Michael, Monti, Riccardo, Morais-Almeida, Mario, Mosges, Ralph, Mullol, Joaquim, Odemyr, Mikaela, Okamoto, Yoshitaka, Papadopoulos, Nikolaos G., Patella, Vincenzo, Pham-Thi, Nhan, Regateiro, Frederico S., Reitsma, Sietze, Rouadi, Philip W., Samolinski, Boleslaw, Sova, Milan, Todo-Bom, Ana, Taborda-Barata, Luis, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Sastre, Joaquin, Tsiligianni, Ioanna, Valiulis, Arunas, Vandenplas, Olivier, Wallace, Dana, Waserman, Susan, Yorgancioglu, Arzu, Zidarn, Mihaela, Zuberbier, Torsten, Fonseca, Joao A., and Bousquet, Jean
Abstract: Background Co-medication is common among patients with allergic rhinitis (AR), but its dimension and patterns are unknown. This is particularly relevant since AR is understood differently across European countries, as reflected by rhinitis-related search patterns in Google Trends. This study aims to assess AR co-medication and its regional patterns in Europe, using real-world data. Methods We analysed 2015-2020 MASK-air(R) European data. We compared days under no medication, monotherapy and co-medication using the visual analogue scale (VAS) levels for overall allergic symptoms ('VAS Global Symptoms') and impact of AR on work. We assessed the monthly use of different medication schemes, performing separate analyses by region (defined geographically or by Google Trends patterns). We estimated the average number of different drugs reported per patient within 1 year. Results We analysed 222,024 days (13,122 users), including 63,887 days (28.8%) under monotherapy and 38,315 (17.3%) under co-medication. The median 'VAS Global Symptoms' was 7 for no medication days, 14 for monotherapy and 21 for co-medication (p < .001). Medication use peaked during the spring, with similar patterns across different European regions (defined geographically or by Google Trends). Oral H-1-antihistamines were the most common medication in single and co-medication. Each patient reported using an annual average of 2.7 drugs, with 80% reporting two or more. Conclusions Allergic rhinitis medication patterns are similar across European regions. One third of treatment days involved co-medication. These findings suggest that patients treat themselves according to their symptoms (irrespective of how they understand AR) and that co-medication use is driven by symptom severity.
Published: 2022

13. A closer look at allergic contact dermatitis caused by topical ophthalmic medications

Author: Alves, Pedro Botelho, primary, Figueiredo, Ana Carolina, additional, Codeço, Carlos, additional, Regateiro, Frederico S., additional, and Gonçalo, Margarida, additional
Published: 2022
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14. Comparison of rhinitis treatments using MASK ‐air® data and considering the minimal important difference

Author: Sousa‐Pinto, Bernardo, primary, Schünemann, Holger J., additional, Sá‐Sousa, Ana, additional, Vieira, Rafael José, additional, Amaral, Rita, additional, Anto, Josep M., additional, Klimek, Ludger, additional, Czarlewski, Wienczyslawa, additional, Mullol, Joaquim, additional, Pfaar, Oliver, additional, Bedbrook, Anna, additional, Brussino, Luisa, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Desirée, additional, Okamoto, Yoshitaka, additional, Ventura, Maria Teresa, additional, Agache, Ioana, additional, Ansotegui, Ignacio J., additional, Bergmann, Karl C., additional, Bosnic‐Anticevich, Sinthia, additional, Brozek, Jan, additional, Canonica, G. Walter, additional, Cardona, Victoria, additional, Carreiro‐Martins, Pedro, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Chivato, Tomas, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Costa, Elísio M., additional, Cruz, Alvaro A., additional, Del Giacco, Stefano, additional, Devillier, Philippe, additional, Eklund, Patrik, additional, Fokkens, Wytske J., additional, Gemicioglu, Bilun, additional, Haahtela, Tari, additional, Ivancevich, Juan Carlos, additional, Ispayeva, Zhanat, additional, Jutel, Marek, additional, Kuna, Piotr, additional, Kaidashev, Igor, additional, Khaitov, Musa, additional, Kraxner, Helga, additional, Laune, Daniel, additional, Lipworth, Brian, additional, Louis, Renaud, additional, Makris, Michael, additional, Monti, Riccardo, additional, Morais‐Almeida, Mario, additional, Mösges, Ralph, additional, Niedoszytko, Marek, additional, Papadopoulos, Nikolaos G., additional, Patella, Vincenzo, additional, Pham‐Thi, Nhân, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Rouadi, Philip W., additional, Samolinski, Boleslaw, additional, Sheikh, Aziz, additional, Sova, Milan, additional, Todo‐Bom, Ana, additional, Taborda‐Barata, Luis, additional, Toppila‐Salmi, Sanna, additional, Sastre, Joaquin, additional, Tsiligianni, Ioanna, additional, Valiulis, Arunas, additional, Vandenplas, Olivier, additional, Wallace, Dana, additional, Waserman, Susan, additional, Yorgancioglu, Arzu, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, Fonseca, Joao A., additional, and Bousquet, Jean, additional
Published: 2022
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15. Systemic allergic contact dermatitis to intravesical mitomycin C

Author: Alves, Marta, primary, Gonçalo, Margarida, additional, Coutinho, Iolanda Alen, additional, Bom, Ana Todo, additional, and Regateiro, Frederico S., additional
Published: 2022
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16. Behavioural patterns in allergic rhinitis medication in Europe: A study using MASK‐air ® real‐world data

Author: Sousa‐Pinto, Bernardo, primary, Sá‐Sousa, Ana, additional, Vieira, Rafael José, additional, Amaral, Rita, additional, Klimek, Ludger, additional, Czarlewski, Wienczyslawa, additional, Antó, Josep M., additional, Pfaar, Oliver, additional, Bedbrook, Anna, additional, Kvedariene, Violeta, additional, Ventura, Maria Teresa, additional, Ansotegui, Ignacio J., additional, Bergmann, Karl‐Christian, additional, Brussino, Luisa, additional, Canonica, G. Walter, additional, Cardona, Victoria, additional, Carreiro‐Martins, Pedro, additional, Casale, Tomas, additional, Cecchi, Lorenzo, additional, Chivato, Tomás, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Costa, Elísio M., additional, Cruz, Alvaro A., additional, De Feo, Giulia, additional, Devillier, Philippe, additional, Fokkens, Wytske J., additional, Gaga, Mina, additional, Gemicioğlu, Bilun, additional, Haahtela, Tari, additional, Ivancevich, Juan Carlos, additional, Ispayeva, Zhanat, additional, Jutel, Marek, additional, Kuna, Piotr, additional, Kaidashev, Igor, additional, Kraxner, Helga, additional, Larenas‐Linnemann, Désirée E., additional, Laune, Daniel, additional, Lipworth, Brian, additional, Louis, Renaud, additional, Makris, Michael, additional, Monti, Riccardo, additional, Morais‐Almeida, Mario, additional, Mösges, Ralph, additional, Mullol, Joaquim, additional, Odemyr, Mikaëla, additional, Okamoto, Yoshitaka, additional, Papadopoulos, Nikolaos G., additional, Patella, Vincenzo, additional, Pham‐Thi, Nhân, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Rouadi, Philip W., additional, Samolinski, Boleslaw, additional, Sova, Milan, additional, Todo‐Bom, Ana, additional, Taborda‐Barata, Luis, additional, Tomazic, Peter Valentin, additional, Toppila‐Salmi, Sanna, additional, Sastre, Joaquin, additional, Tsiligianni, Ioanna, additional, Valiulis, Arunas, additional, Vandenplas, Olivier, additional, Wallace, Dana, additional, Waserman, Susan, additional, Yorgancioglu, Arzu, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, Fonseca, João A., additional, and Bousquet, Jean, additional
Published: 2022
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17. Allergies and COVID‐19 vaccines: An ENDA/EAACI Position paper

Author: Barbaud, Annick, primary, Garvey, Lene Heise, additional, Arcolaci, Alessandra, additional, Brockow, Knut, additional, Mori, Francesca, additional, Mayorga, Cristobalina, additional, Bonadonna, Patrizia, additional, Atanaskovic‐Markovic, Marina, additional, Moral, Luis, additional, Zanoni, Giovanna, additional, Pagani, Mauro, additional, Soria, Angèle, additional, Jošt, Maja, additional, Caubet, Jean‐Christoph, additional, Carmo, Abreu, additional, Mona, Al‐Ahmad, additional, Alvarez‐Perea, Alberto, additional, Bavbek, Sevim, additional, Benedetta, Biagioni, additional, Bilo, M.Beatrice, additional, Blanca‐López, Natalia, additional, Bogas, Herrera Gádor, additional, Buonomo, Alessandro, additional, Calogiuri, Gianfranco, additional, Carli, Giulia, additional, Cernadas, Josefina, additional, Cortellini, Gabriele, additional, Celik, Gülfem, additional, Demir, Semra, additional, Doña, Inmaculada, additional, Dursun, Adile Berna, additional, Eberlein, Bernadette, additional, Faria, Emilia, additional, Fernandes, Bryan, additional, Garcez, Tomaz, additional, Garcia‐Nunez, Ignacio, additional, Gawlik, Radoslaw, additional, Gelincik, Asli, additional, Gomes, Eva, additional, Gooi, Jimmy H. C., additional, Grosber, Martine, additional, Gülen, Theo, additional, Hacard, Florence, additional, Hoarau, Cyrille, additional, Janson, Christer, additional, Johnston, Sebastian L., additional, Joerg, Lukas, additional, Kepil Özdemir, Seçil, additional, Klimek, Ludger, additional, Košnik, Mitja, additional, Kowalski, Marek L., additional, Kuyucu, Semanur, additional, Kvedariene, Violeta, additional, Laguna, Jose Julio, additional, Lombardo, Carla, additional, Marinho, Susana, additional, Merk, Hans, additional, Meucci, Elisa, additional, Morisset, Martine, additional, Munoz‐Cano, Rosa, additional, Murzilli, Francesco, additional, Nakonechna, Alla, additional, Popescu, Florin‐Dan, additional, Porebski, Grzegorz, additional, Radice, Anna, additional, Regateiro, Frederico S., additional, Röckmann, Heike, additional, Romano, Antonino, additional, Sargur, Ravishankar, additional, Sastre, Joaquin, additional, Scherer Hofmeier, Kathrin, additional, Sedláčková, Lenka, additional, Sobotkova, Marta, additional, Terreehorst, Ingrid, additional, Treudler, Regina, additional, Walusiak‐Skorupa, Jolanta, additional, Wedi, Bettina, additional, Wöhrl, Stefan, additional, Zidarn, Mihael, additional, Zuberbier, Torsten, additional, Agache, Ioana, additional, and Torres, Maria J., additional
Published: 2022
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18. Allergen immunotherapy in MASK‐air users in real‐life: Results of a Bayesian mixed‐effects model

Author: Sousa‐Pinto, Bernardo, primary, Azevedo, Luís Filipe, additional, Sá‐Sousa, Ana, additional, Vieira, Rafael José, additional, Amaral, Rita, additional, Klimek, Ludger, additional, Czarlewski, Wienczyslawa, additional, Anto, Josep M., additional, Bedbrook, Anna, additional, Kvedariene, Violeta, additional, Ventura, Maria Teresa, additional, Ansotegui, Ignacio J., additional, Bergmann, Karl‐Christian, additional, Brussino, Luisa, additional, Canonica, G. Walter, additional, Cardona, Victoria, additional, Carreiro‐Martins, Pedro, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Chivato, Tomás, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Costa, Elisio M., additional, Cruz, Alvaro A., additional, De Feo, Giulia, additional, Devillier, Philippe, additional, Fokkens, Wytske J., additional, Gaga, Mina, additional, Gemicioğlu, Bilun, additional, Haahtela, Tari, additional, Ivancevich, Juan Carlos, additional, Ispayeva, Zhanat, additional, Jutel, Marek, additional, Kuna, Piotr, additional, Kaidashev, Igor, additional, Kraxner, Helga, additional, Larenas‐Linnemann, Désirée E., additional, Laune, Daniel, additional, Lipworth, Brian, additional, Louis, Renaud, additional, Makris, Michaël, additional, Monti, Riccardo, additional, Morais‐Almeida, Mario, additional, Mösges, Ralph, additional, Mullol, Joaquim, additional, Odemyr, Mikaëla, additional, Okamoto, Yoshitaka, additional, Papadopoulos, Nikolaos G., additional, Patella, Vincenzo, additional, Pham‐Thi, Nhân, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Rouadi, Philip W., additional, Samolinski, Boleslaw, additional, Sova, Milan, additional, Todo‐Bom, Ana, additional, Taborda‐Barata, Luis, additional, Tomazic, Peter Valentin, additional, Toppila‐Salmi, Sanna, additional, Sastre, Joaquin, additional, Tsiligianni, Ioanna, additional, Valiulis, Arunas, additional, Wallace, Dana, additional, Waserman, Susan, additional, Yorgancioglu, Arzu, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, Fonseca, João Almeida, additional, Bousquet, Jean, additional, and Pfaar, Oliver, additional
Published: 2022
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19. Patient‐reported outcome measures (PROMs) using the MASK‐air ® app in severe asthma

Author: Sousa‐Pinto, Bernardo, primary, Fonseca, Joao A., additional, Gemicioglu, Bilun, additional, Regateiro, Frederico S., additional, Scichilone, Nicola, additional, Ventura, Maria Teresa, additional, and Bousquet, Jean, additional
Published: 2022
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20. Development and validation of combined symptom‐medication scores for allergic rhinitis*

Author: Sousa‐Pinto, Bernardo, primary, Azevedo, Luís Filipe, additional, Jutel, Marek, additional, Agache, Ioana, additional, Canonica, G. Walter, additional, Czarlewski, Wienczyslawa, additional, Papadopoulos, Nikolaos G., additional, Bergmann, Karl‐Christian, additional, Devillier, Philippe, additional, Laune, Daniel, additional, Klimek, Ludger, additional, Anto, Aram, additional, Anto, Josep M., additional, Eklund, Patrik, additional, Almeida, Rute, additional, Bedbrook, Anna, additional, Bosnic‐Anticevich, Sinthia, additional, Brough, Helen A., additional, Brussino, Luisa, additional, Cardona, Victoria, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Charpin, Denis, additional, Chivato, Tomás, additional, Costa, Elisio M., additional, Cruz, Alvaro A., additional, Dramburg, Stephanie, additional, Durham, Stephen R., additional, De Feo, Giulia, additional, Gerth van Wijk, Roy, additional, Fokkens, Wystke J., additional, Gemicioglu, Bilun, additional, Haahtela, Tari, additional, Illario, Maddalena, additional, Ivancevich, Juan Carlos, additional, Kvedariene, Violeta, additional, Kuna, Piotr, additional, Larenas‐Linnemann, Désirée E., additional, Makris, Michael, additional, Mathieu‐Dupas, Eve, additional, Melén, Erik, additional, Morais‐Almeida, Mario, additional, Mösges, Ralph, additional, Mullol, Joaquim, additional, Nadeau, Kari C., additional, Pham‐Thi, Nhân, additional, O’Hehir, Robyn, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Samolinski, Boleslaw, additional, Sheikh, Aziz, additional, Stellato, Cristiana, additional, Todo‐Bom, Ana, additional, Tomazic, Peter Valentin, additional, Toppila‐Salmi, Sanna, additional, Valero, Antonio, additional, Valiulis, Arunas, additional, Ventura, Maria Teresa, additional, Wallace, Dana, additional, Waserman, Susan, additional, Yorgancioglu, Arzu, additional, De Vries, Govert, additional, van Eerd, Michiel, additional, Zieglmayer, Petra, additional, Zuberbier, Torsten, additional, Pfaar, Oliver, additional, Almeida Fonseca, João, additional, and Bousquet, Jean, additional
Published: 2022
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21. Management of anaphylaxis due to COVID‐19 vaccines in the elderly

Author: Bousquet, Jean, primary, Agache, Ioana, additional, Blain, Hubert, additional, Jutel, Marek, additional, Ventura, Maria Teresa, additional, Worm, Margitta, additional, Del Giacco, Stefano, additional, Benetos, Athanasios, additional, Bilo, Beatrice Maria, additional, Czarlewski, Wienczyslawa, additional, Abdul Latiff, Amir Hamzah, additional, Al‐Ahmad, Mona, additional, Angier, Elizabeth, additional, Annesi‐Maesano, Isabella, additional, Atanaskovic‐Markovic, Marina, additional, Bachert, Claus, additional, Barbaud, Annick, additional, Bedbrook, Anna, additional, Bennoor, Kazi S., additional, Berghea, Elena Camelia, additional, Bindslev‐Jensen, Carsten, additional, Bonini, Sergio, additional, Bosnic‐Anticevich, Sinthia, additional, Brockow, Knut, additional, Brussino, Luisa, additional, Camargos, Paulo, additional, Canonica, G. Walter, additional, Cardona, Victoria, additional, Carreiro‐Martins, Pedro, additional, Carriazo, Ana, additional, Casale, Thomas, additional, Caubet, Jean‐Christoph, additional, Cecchi, Lorenzo, additional, Cherubini, Antonio, additional, Christoff, George, additional, Chu, Derek K., additional, Cruz, Alvaro A., additional, Dokic, Dejan, additional, El‐Gamal†, Yehia, additional, Ebisawa, Motohiro, additional, Eberlein, Bernadette, additional, Farrell, John, additional, Fernandez‐Rivas, Montserrat, additional, Fokkens, Wytske J., additional, Fonseca, Joao A., additional, Gao, Yadong, additional, Gavazzi, Gaëtan, additional, Gawlik, Radoslaw, additional, Gelincik, Asli, additional, Gemicioğlu, Bilun, additional, Gotua, Maia, additional, Guérin, Olivier, additional, Haahtela, Tari, additional, Hoffmann‐Sommergruber, Karin, additional, Hoffmann, Hans Jürgen, additional, Hofmann, Maja, additional, Hrubisko, Martin, additional, Illario, Maddalena, additional, Irani, Carla, additional, Ispayeva, Zhanat, additional, Ivancevich, Juan Carlos, additional, Julge, Kaja, additional, Kaidashev, Igor, additional, Khaitov, Musa, additional, Knol, Edward, additional, Kraxner, Helga, additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Lauerma, Antti, additional, Le, Lan T. T., additional, Le Moing, Vincent, additional, Levin, Michael, additional, Louis, Renaud, additional, Lourenco, Olga, additional, Mahler, Vera, additional, Martin, Finbarr C., additional, Matucci, Andrea, additional, Milenkovic, Branislava, additional, Miot, Stéphanie, additional, Montella, Emma, additional, Morais‐Almeida, Mario, additional, Mortz, Charlotte G., additional, Mullol, Joaquim, additional, Namazova‐Baranova, Leyla, additional, Neffen, Hugo, additional, Nekam, Kristof, additional, Niedoszytko, Marek, additional, Odemyr, Mikaëla, additional, O’Hehir, Robyn E., additional, Okamoto, Yoshitaka, additional, Ollert, Markus, additional, Palomares, Oscar, additional, Papadopoulos, Nikolaos G., additional, Panzner, Petr, additional, Passalacqua, Giovanni, additional, Patella, Vincenzo, additional, Petrovic, Mirko, additional, Pfaar, Oliver, additional, Pham‐Thi, Nhân, additional, Plavec, Davor, additional, Popov, Todor A., additional, Recto, Marysia T., additional, Regateiro, Frederico S., additional, Reynes, Jacques, additional, Roller‐Winsberger, Regina E., additional, Rolland, Yves, additional, Romano, Antonino, additional, Rondon, Carmen, additional, Rottem, Menachem, additional, Rouadi, Philip W., additional, Salles, Nathalie, additional, Samolinski, Boleslaw, additional, Santos, Alexandra F., additional, S Sarquis, Faradiba, additional, Sastre, Joaquin, additional, M. G. A. Schols, Jos, additional, Scichilone, Nicola, additional, Sediva, Anna, additional, Shamji, Mohamed H., additional, Sheikh, Aziz, additional, Skypala, Isabel, additional, Smolinska, Sylwia, additional, Sokolowska, Milena, additional, Sousa‐Pinto, Bernardo, additional, Sova, Milan, additional, Stelmach, Rafael, additional, Sturm, Gunter, additional, Suppli Ulrik, Charlotte, additional, Todo‐Bom, Ana Maria, additional, Toppila‐Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Torres, Maria, additional, Untersmayr, Eva, additional, Urrutia Pereira, Marilyn, additional, Valiulis, Arunas, additional, Vitte, Joana, additional, Vultaggio, Alessandra, additional, Wallace, Dana, additional, Walusiak‐Skorupa, Jolanta, additional, Wang, De‐Yun, additional, Waserman, Susan, additional, Yorgancioglu, Arzu, additional, Yusuf, Osman M., additional, Zernotti, Mario, additional, Zidarn, Mihaela, additional, Chivato, Tomas, additional, Akdis, Cezmi A., additional, Zuberbier, Torsten, additional, and Klimek, Ludger, additional
Published: 2021
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22. Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK‐air®

Author: Sousa‐Pinto, Bernardo, primary, Eklund, Patrik, additional, Pfaar, Oliver, additional, Klimek, Ludger, additional, Zuberbier, Torsten, additional, Czarlewski, Wienczyslawa, additional, Bédard, Annabelle, additional, Bindslev‐Jensen, Carsten, additional, Bedbrook, Anna, additional, Bosnic‐Anticevich, Sinthia, additional, Brussino, Luisa, additional, Cardona, Victoria, additional, Cruz, Alvaro A., additional, Vries, Govert, additional, Devillier, Philippe, additional, Fokkens, Wytske J., additional, Fuentes‐Pérez, José Miguel, additional, Gemicioğlu, Bilun, additional, Haahtela, Tari, additional, Huerta‐Villalobos, Yunen Rocío, additional, Ivancevich, Juan Carlos, additional, Kull, Inger, additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Larenas Linnemann, Désirée E., additional, Laune, Daniel, additional, Makris, Michael, additional, Melén, Erik, additional, Morais‐Almeida, Mário, additional, Mösges, Ralph, additional, Mullol, Joaquim, additional, O'Hehir, Robyn E., additional, Papadopoulos, Nikolaos G., additional, Pereira, Ana Margarida, additional, Prokopakis, Emmanuel P., additional, Psarros, Fotis, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Samolinski, Boleslaw, additional, Scichilone, Nicola, additional, Silva, Jane, additional, Stellato, Cristiana, additional, Todo‐Bom, Ana, additional, Tomazic, Peter Valentin, additional, Salmi, Sanna Toppila, additional, Valero, Antonio, additional, Valiulis, Arunas, additional, Valovirta, Erkka, additional, Eerd, Michiel, additional, Ventura, Maria Teresa, additional, Yorgancioglu, Arzu, additional, Basagaña, Xavier, additional, Antó, Josep M., additional, Bousquet, Jean, additional, and Fonseca, João Almeida, additional
Published: 2021
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23. Validity, reliability, and responsiveness of daily monitoring visual analog scales in MASK-air (R)

Author: Sousa-Pinto, Bernardo, Eklund, Patrik, Pfaar, Oliver, Klimek, Ludger, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedard, Annabelle, Bindslev-Jensen, Carsten, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Brussino, Luisa, Cardona, Victoria, Cruz, Alvaro A., de Vries, Govert, Devillier, Philippe, Fokkens, Wytske J., Miguel Fuentes-Perez, Jose, Gemicioglu, Bilun, Haahtela, Tari, Rocio Huerta-Villalobos, Yunen, Carlos Ivancevich, Juan, Kull, Inger, Kuna, Piotr, Kvedariene, Violeta, Larenas Linnemann, Desiree E., Laune, Daniel, Makris, Michael, Melen, Erik, Morais-Almeida, Mario, Moesges, Ralph, Mullol, Joaquim, O'Hehir, Robyn E., Papadopoulos, Nikolaos G., Pereira, Ana Margarida, Prokopakis, Emmanuel P., Psarros, Fotis, Regateiro, Frederico S., Reitsma, Sietze, Samolinski, Boleslaw, Scichilone, Nicola, da Silva, Jane, Stellato, Cristiana, Todo-Bom, Ana, Tomazic, Peter Valentin, Salmi, Sanna Toppila, Valero, Antonio, Valiulis, Arunas, Valovirta, Erkka, van Eerd, Michiel, Ventura, Maria Teresa, Yorgancioglu, Arzu, Basagana, Xavier, Anto, Josep M., Bousquet, Jean, Fonseca, Joao Almeida, Sousa-Pinto, Bernardo, Eklund, Patrik, Pfaar, Oliver, Klimek, Ludger, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedard, Annabelle, Bindslev-Jensen, Carsten, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Brussino, Luisa, Cardona, Victoria, Cruz, Alvaro A., de Vries, Govert, Devillier, Philippe, Fokkens, Wytske J., Miguel Fuentes-Perez, Jose, Gemicioglu, Bilun, Haahtela, Tari, Rocio Huerta-Villalobos, Yunen, Carlos Ivancevich, Juan, Kull, Inger, Kuna, Piotr, Kvedariene, Violeta, Larenas Linnemann, Desiree E., Laune, Daniel, Makris, Michael, Melen, Erik, Morais-Almeida, Mario, Moesges, Ralph, Mullol, Joaquim, O'Hehir, Robyn E., Papadopoulos, Nikolaos G., Pereira, Ana Margarida, Prokopakis, Emmanuel P., Psarros, Fotis, Regateiro, Frederico S., Reitsma, Sietze, Samolinski, Boleslaw, Scichilone, Nicola, da Silva, Jane, Stellato, Cristiana, Todo-Bom, Ana, Tomazic, Peter Valentin, Salmi, Sanna Toppila, Valero, Antonio, Valiulis, Arunas, Valovirta, Erkka, van Eerd, Michiel, Ventura, Maria Teresa, Yorgancioglu, Arzu, Basagana, Xavier, Anto, Josep M., Bousquet, Jean, and Fonseca, Joao Almeida
Abstract: Background MASK-air (R) is an app that supports allergic rhinitis patients in disease control. Users register daily allergy symptoms and their impact on activities using visual analog scales (VASs). We aimed to assess the concurrent validity, reliability, and responsiveness of these daily VASs. Methods Daily monitoring VAS data were assessed in MASK-air (R) users with allergic rhinitis. Concurrent validity was assessed by correlating daily VAS values with those of the EuroQol-5 Dimensions (EQ-5D) VAS, the Control of Allergic Rhinitis and Asthma Test (CARAT) score, and the Work Productivity and Activity Impairment Allergic Specific (WPAI-AS) Questionnaire (work and activity impairment scores). Intra-rater reliability was assessed in users providing multiple daily VASs within the same day. Test-retest reliability was tested in clinically stable users, as defined by the EQ-5D VAS, CARAT, or VAS Work (i.e., VAS assessing the impact of allergy on work). Responsiveness was determined in users with two consecutive measurements of EQ-5D-VAS or VAS Work indicating clinical change. Results A total of 17,780 MASK-air (R) users, with 317,176 VAS days, were assessed. Concurrent validity was moderate-high (Spearman correlation coefficient range: 0.437-0.716). Intra-rater reliability intraclass correlation coefficients (ICCs) ranged between 0.870 (VAS assessing global allergy symptoms) and 0.937 (VAS assessing allergy symptoms on sleep). Test-retest reliability ICCs ranged between 0.604 and 0.878-VAS Work and VAS asthma presented the highest ICCs. Moderate/large responsiveness effect sizes were observed-the sleep VAS was associated with lower responsiveness, while the global allergy symptoms VAS demonstrated higher responsiveness. Conclusion In MASK-air (R), daily monitoring VASs have high intra-rater reliability and moderate-high validity, reliability, and responsiveness, pointing to a reliable measure of symptom loads.
Published: 2021

24. ARIA‐EAACI care pathways for allergen immunotherapy in respiratory allergy

Author: Bousquet, Jean, primary, Pfaar, Oliver, additional, Agache, Ioana, additional, Bedbrook, Anna, additional, Akdis, Cezmi A, additional, Canonica, G. Walter, additional, Chivato, Tomas, additional, Al‐Ahmad, Mona, additional, Abdul Latiff, Amir H, additional, Ansotegui, Ignacio J, additional, Bachert, Claus, additional, Baharuddin, Abdullah, additional, Bergmann, Karl‐Christian, additional, Bindslev‐Jensen, Carsten, additional, Bjermer, Leif, additional, Bonini, Matteo, additional, Bosnic‐Anticevich, Sinthia, additional, Bosse, Isabelle, additional, Brough, Helen A., additional, Brussino, Luisa, additional, Calderon, Moises A, additional, Caraballo, Luis, additional, Cardona, Victoria, additional, Carreiro‐Martins, Pedro, additional, Casale, Tomas, additional, Cecchi, Lorenzo, additional, Cepeda Sarabia, Alfonso M, additional, Chkhartishvili, Ekaterine, additional, Chu, Derek K, additional, Cirule, Ieva, additional, Cruz, Alvaro A, additional, Czarlewski, Wienczyslawa, additional, del Giacco, Stefano, additional, Demoly, Pascal, additional, Devillier, Philippe, additional, Dokic, Dejan, additional, Durham, Stephen L, additional, Ebisawa, Motohiro, additional, El‐Gamal✝, Yehia, additional, Emuzyte, Regina, additional, Gamkrelidze, Amiran, additional, Fauquert, Jean Luc, additional, Fiocchi, Alessandro, additional, Fokkens, Wytske J, additional, Fonseca, Joao A, additional, Fontaine, Jean‐François, additional, Gawlik, Radoslaw, additional, Gelincik, Asli, additional, Gemicioglu, Bilun, additional, Gereda, Jose E, additional, Gerth van Wijk, Roy, additional, Gomez, R Maximiliano, additional, Gotua, Maia, additional, Grisle, Ineta, additional, Guzmán, Maria‐Antonieta, additional, Haahtela, Tari, additional, Halken, Susanne, additional, Heffler, Enrico, additional, Hoffmann‐Sommergruber, Karin, additional, Hossny, Elham, additional, Hrubiško, Martin, additional, Irani, Carla, additional, Ivancevich, Juan Carlos, additional, Ispayeva, Zhanat, additional, Julge, Kaja, additional, Kaidashev, Igor, additional, Kalayci, Omer, additional, Khaitov, Musa, additional, Klimek, Ludger, additional, Knol, Edward, additional, Kowalski, Marek L, additional, Kraxner, Helga, additional, Kull, Inger, additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Kritikos, Vicky, additional, Lauerma, Antti, additional, Lau, Susanne, additional, Laune, Daniel, additional, Levin, Michael, additional, Larenas‐Linnemann, Desiree E, additional, Lodrup Carlsen, Karin C, additional, Lombardi, Carlo, additional, Lourenço, Olga M, additional, Mahboub, Bassam, additional, Malling, Hans‐Jørgen, additional, Manning, Patrick, additional, Marshall, Gailen D, additional, Melén, Erik, additional, Meltzer, Eli O, additional, Miculinic, Neven, additional, Milenkovic, Branislava, additional, Moin, Mostafa, additional, Montefort, Stephen, additional, Morais‐Almeida, Mario, additional, Mortz, Charlotte G, additional, Mösges, Ralph, additional, Mullol, Joaquim, additional, Namazova Baranova, Leyla, additional, Neffen, Hugo, additional, Nekam, Kristof, additional, Niedoszytko, Marek, additional, Odemyr, Mikaëla, additional, O'Hehir, Robyn E, additional, Ollert, Markus, additional, O'Mahony, Liam, additional, Ohta, Ken, additional, Okamoto, Yoshitaka, additional, Okubo, Kimi, additional, Pajno, Giovanni B, additional, Palomares, Oscar, additional, Palkonen, Susanna, additional, Panzner, Petr, additional, G Papadopoulos, Nikolaos, additional, Park, Hae‐Sim, additional, Passalacqua, Giovanni, additional, Patella, Vincenzo, additional, Pawankar, Ruby, additional, Pham‐Thi, Nhân, additional, Plavec, Davor, additional, Popov, Todor A, additional, Recto, Marysia, additional, Regateiro, Frederico S, additional, Riggioni, Carmen, additional, Roberts, Graham, additional, Rodriguez‐Gonzales, Monica, additional, Rosario, Nelson, additional, Rottem, Menachem, additional, Rouadi, Philip W, additional, Ryan, Dermot, additional, Samolinski, Boleslaw, additional, Sanchez‐Borges✝, Mario, additional, Serpa, Faradiba S, additional, Sastre, Joaquin, additional, Scadding, Glenis K., additional, Shamji, Mohamed H, additional, Schmid‐Grendelmeier, Peter, additional, Schünemann, Holger J, additional, Sheikh, Aziz, additional, Scichilone, Nicola, additional, Sisul, Juan Carlos, additional, Sofiev, Mikhail, additional, Solé, Dirceu, additional, Sooronbaev, Talant, additional, Soto‐Martinez, Manuel, additional, Soto‐Quiros, Manuel, additional, Sova, Milan, additional, Schwarze, Jürgen, additional, Skypala, Isabel, additional, Suppli‐Ulrik, Charlotte, additional, Taborda‐Barata, Luis, additional, Todo‐Bom, Ana, additional, Torres, Maria J, additional, Valentin‐Rostan, Marylin, additional, Tomazic, Peter‐Valentin, additional, Valero, Antonio, additional, Toppila‐Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Untersmayr, Eva, additional, Urrutia‐Pereira, Marilyn, additional, Valiulis, Arunas, additional, Valovirta, Erkka, additional, Vandenplas, Olivier, additional, Ventura, Maria Teresa, additional, Vichyanond, Pakit, additional, Wagenmann, Martin, additional, Wallace, Dana, additional, Walusiak‐Skorupa, Jolanta, additional, Wang, De Yun, additional, Waserman, Susan, additional, Wong, Gary WK, additional, Yorgancioglu, Arzu, additional, Yusuf, Osman M, additional, Zernotti, Mario, additional, Zhang, Luo, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, and Jutel, Marek, additional
Published: 2021
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25. Concomitant allergic contact dermatitis and aquagenic urticaria caused by personal protective equipment in a healthcare worker during the COVID ‐19 pandemic

Author: Alves, Pedro Botelho, primary, Alves, Marta Pires, additional, Todo‐Bom, Ana, additional, and Regateiro, Frederico S., additional
Published: 2021
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26. Differentiation of COVID‐19 signs and symptoms from allergic rhinitis and common cold: An ARIA‐EAACI‐GA2LEN consensus

Author: Hagemann, Jan, primary, Onorato, Gabrielle L., additional, Jutel, Marek, additional, Akdis, Cezmi A., additional, Agache, Ioana, additional, Zuberbier, Torsten, additional, Czarlewski, Wienczyslawa, additional, Mullol, Joaquim, additional, Bedbrook, Anna, additional, Bachert, Claus, additional, Bennoor, Kazi S., additional, Bergmann, Karl‐Christian, additional, Braido, Fulvio, additional, Camargos, Paulo, additional, Caraballo, Luis, additional, Cardona, Victoria, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Chivato, Tomas, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Correia‐de‐Sousa, Jaime, additional, del Giacco, Stefano, additional, Dokic, Dejan, additional, Dykewicz, Mark, additional, Ebisawa, Motohiro, additional, El‐Gamal, Yehia, additional, Emuzyte, Regina, additional, Fauquert, Jean‐Luc, additional, Fiocchi, Alessandro, additional, Fokkens, Wytske J., additional, Fonseca, Joao A., additional, Gemicioglu, Bilun, additional, Gomez, René‐Maximiliano, additional, Gotua, Maia, additional, Haahtela, Tari, additional, Hamelmann, Eckard, additional, Iinuma, Tomohisa, additional, Ivancevich, Juan Carlos, additional, Jassem, Ewa, additional, Kalayci, Omer, additional, Kardas, Przemyslaw, additional, Khaitov, Musa, additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Desiree E., additional, Lipworth, Brian, additional, Makris, Michael, additional, Maspero, Jorge F., additional, Miculinic, Neven, additional, Mihaltan, Florin, additional, Mohammad, Yousser, additional, Montefort, Stephen, additional, Morais‐Almeida, Mario, additional, Mösges, Ralph, additional, Naclerio, Robert, additional, Neffen, Hugo, additional, Niedoszytko, Marek, additional, O’Hehir, Robyn E., additional, Ohta, Ken, additional, Okamoto, Yoshitaka, additional, Okubo, Kimi, additional, Panzner, Petr, additional, Papadopoulos, Nikolaos G., additional, Passalacqua, Giovanni, additional, Patella, Vincenzo, additional, Pereira, Ana, additional, Pfaar, Oliver, additional, Plavec, Davor, additional, Popov, Todor A., additional, Prokopakis, Emmanuel P., additional, Puggioni, Francesca, additional, Raciborski, Filip, additional, Reijula, Jere, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Romano, Antonino, additional, Rosario, Nelson, additional, Rottem, Menachem, additional, Ryan, Dermot, additional, Samolinski, Boleslaw, additional, Sastre, Joaquin, additional, Solé, Dirceu, additional, Sova, Milan, additional, Stellato, Cristiana, additional, Suppli‐Ulrik, Charlotte, additional, Tsiligianni, Ioanna, additional, Valero, Antonio, additional, Valiulis, Arunas, additional, Valovirta, Erkka, additional, Vasankari, Tuula, additional, Ventura, Maria Teresa, additional, Wallace, Dana, additional, Wang, De Yun, additional, Williams, Siân, additional, Yorgancioglu, Arzu, additional, Yusuf, Osman M., additional, Zernotti, Mario, additional, Bousquet, Jean, additional, and Klimek, Ludger, additional
Published: 2021
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27. COVID‐19 pandemic: Practical considerations on the organization of an allergy clinic—An EAACI/ARIA Position Paper

Author: Pfaar, Oliver, primary, Klimek, Ludger, additional, Jutel, Marek, additional, Akdis, Cezmi A., additional, Bousquet, Jean, additional, Breiteneder, Heimo, additional, Chinthrajah, Sharon, additional, Diamant, Zuzana, additional, Eiwegger, Thomas, additional, Fokkens, Wytske J., additional, Fritsch, Hans‐Walter, additional, Nadeau, Kari C., additional, O’Hehir, Robyn E., additional, O’Mahony, Liam, additional, Rief, Winfried, additional, Sampath, Vanitha, additional, Schedlowski, Manfred, additional, Torres, María José, additional, Traidl‐Hoffmann, Claudia, additional, Wang, De Yun, additional, Zhang, Luo, additional, Bonini, Matteo, additional, Brehler, Randolf, additional, Brough, Helen Annaruth, additional, Chivato, Tomás, additional, Del Giacco, Stefano R., additional, Dramburg, Stephanie, additional, Gawlik, Radoslaw, additional, Gelincik, Aslı, additional, Hoffmann‐Sommergruber, Karin, additional, Hox, Valerie, additional, Knol, Edward F., additional, Lauerma, Antti, additional, Matricardi, Paolo M., additional, Mortz, Charlotte G., additional, Ollert, Markus, additional, Palomares, Oscar, additional, Riggioni, Carmen, additional, Schwarze, Jürgen, additional, Skypala, Isabel, additional, Untersmayr, Eva, additional, Walusiak‐Skorupa, Jolanta, additional, Ansotegui, Ignacio J., additional, Bachert, Claus, additional, Bedbrook, Anna, additional, Bosnic‐Anticevich, Sinthia, additional, Brussino, Luisa, additional, Canonica, Giorgio Walter, additional, Cardona, Victoria, additional, Carreiro‐Martins, Pedro, additional, Cruz, Alvaro A., additional, Czarlewski, Wienczyslawa, additional, Fonseca, João A., additional, Gotua, Maia, additional, Haahtela, Tari, additional, Ivancevich, Juan Carlos, additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Désirée Erlinda, additional, Abdul Latiff, Amir Hamzah, additional, Mäkelä, Mika, additional, Morais‐Almeida, Mário, additional, Mullol, Joaquim, additional, Naclerio, Robert, additional, Ohta, Ken, additional, Okamoto, Yoshitaka, additional, Onorato, Gabrielle L., additional, Papadopoulos, Nikolaos G., additional, Patella, Vincenzo, additional, Regateiro, Frederico S., additional, Samoliński, Bolesław, additional, Suppli Ulrik, Charlotte, additional, Toppila‐Salmi, Sanna, additional, Valiulis, Arunas, additional, Ventura, Maria‐Teresa, additional, Yorgancioglu, Arzu, additional, Zuberbier, Torsten, additional, and Agache, Ioana, additional
Published: 2021
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28. ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice

Author: Bousquet, Jean, primary, Anto, Josep M., additional, Bachert, Claus, additional, Haahtela, Tari, additional, Zuberbier, Torsten, additional, Czarlewski, Wienczyslawa, additional, Bedbrook, Anna, additional, Bosnic‐Anticevich, Sinthia, additional, Walter Canonica, G., additional, Cardona, Victoria, additional, Costa, Elisio, additional, Cruz, Alvaro A., additional, Erhola, Marina, additional, Fokkens, Wytske J., additional, Fonseca, Joao A., additional, Illario, Maddalena, additional, Ivancevich, Juan‐Carlos, additional, Jutel, Marek, additional, Klimek, Ludger, additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Le, LTT, additional, Larenas‐Linnemann, Désirée E., additional, Laune, Daniel, additional, Lourenço, Olga M., additional, Melén, Erik, additional, Mullol, Joaquim, additional, Niedoszytko, Marek, additional, Odemyr, Mikaëla, additional, Okamoto, Yoshitaka, additional, Papadopoulos, Nikos G., additional, Patella, Vincenzo, additional, Pfaar, Oliver, additional, Pham‐Thi, Nhân, additional, Rolland, Christine, additional, Samolinski, Boleslaw, additional, Sheikh, Aziz, additional, Sofiev, Mikhail, additional, Suppli Ulrik, Charlotte, additional, Todo‐Bom, Ana, additional, Tomazic, Peter‐Valentin, additional, Toppila‐Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Valiulis, Arunas, additional, Valovirta, Erkka, additional, Ventura, Maria‐Teresa, additional, Walker, Samantha, additional, Williams, Sian, additional, Yorgancioglu, Arzu, additional, Agache, Ioana, additional, Akdis, Cezmi A., additional, Almeida, Rute, additional, Ansotegui, Ignacio J., additional, Annesi‐Maesano, Isabella, additional, Arnavielhe, Sylvie, additional, Basagaña, Xavier, additional, D. Bateman, Eric, additional, Bédard, Annabelle, additional, Bedolla‐Barajas, Martin, additional, Becker, Sven, additional, Bennoor, Kazi S., additional, Benveniste, Samuel, additional, Bergmann, Karl C., additional, Bewick, Michael, additional, Bialek, Slawomir, additional, E. Billo, Nils, additional, Bindslev‐Jensen, Carsten, additional, Bjermer, Leif, additional, Blain, Hubert, additional, Bonini, Matteo, additional, Bonniaud, Philippe, additional, Bosse, Isabelle, additional, Bouchard, Jacques, additional, Boulet, Louis‐Philippe, additional, Bourret, Rodolphe, additional, Boussery, Koen, additional, Braido, Fluvio, additional, Briedis, Vitalis, additional, Briggs, Andrew, additional, Brightling, Christopher E., additional, Brozek, Jan, additional, Brusselle, Guy, additional, Brussino, Luisa, additional, Buhl, Roland, additional, Buonaiuto, Roland, additional, Calderon, Moises A., additional, Camargos, Paulo, additional, Camuzat, Thierry, additional, Caraballo, Luis, additional, Carriazo, Ana‐Maria, additional, Carr, Warner, additional, Cartier, Christine, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Cepeda Sarabia, Alfonso M., additional, H. Chavannes, Niels, additional, Chkhartishvili, Ekaterine, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Correia de Sousa, Jaime, additional, Costa, David J., additional, Courbis, Anne‐Lise, additional, Custovic, Adnan, additional, Cvetkosvki, Biljana, additional, D'Amato, Gennaro, additional, da Silva, Jane, additional, Dantas, Carina, additional, Dokic, Dejan, additional, Dauvilliers, Yves, additional, De Feo, Giulia, additional, De Vries, Govert, additional, Devillier, Philippe, additional, Di Capua, Stefania, additional, Dray, Gerard, additional, Dubakiene, Ruta, additional, Durham, Stephen R., additional, Dykewicz, Mark, additional, Ebisawa, Motohiro, additional, Gaga, Mina, additional, El‐Gamal, Yehia, additional, Heffler, Enrico, additional, Emuzyte, Regina, additional, Farrell, John, additional, Fauquert, Jean‐Luc, additional, Fiocchi, Alessandro, additional, Fink‐Wagner, Antje, additional, Fontaine, Jean‐François, additional, Fuentes Perez, José M., additional, Gemicioğlu, Bilun, additional, Gamkrelidze, Amiran, additional, Garcia‐Aymerich, Judith, additional, Gevaert, Philippe, additional, Gomez, René Maximiliano, additional, González Diaz, Sandra, additional, Gotua, Maia, additional, Guldemond, Nick A., additional, Guzmán, Maria‐Antonieta, additional, Hajjam, Jawad, additional, Huerta Villalobos, Yunuen R., additional, Humbert, Marc, additional, Iaccarino, Guido, additional, Ierodiakonou, Despo, additional, Iinuma, Tomohisa, additional, Jassem, Ewa, additional, Joos, Guy, additional, Jung, Ki‐Suck, additional, Kaidashev, Igor, additional, Kalayci, Omer, additional, Kardas, Przemyslaw, additional, Keil, Thomas, additional, Khaitov, Musa, additional, Khaltaev, Nikolai, additional, Kleine‐Tebbe, Jorg, additional, Kouznetsov, Rostislav, additional, Kowalski, Marek L., additional, Kritikos, Vicky, additional, Kull, Inger, additional, La Grutta, Stefania, additional, Leonardini, Lisa, additional, Ljungberg, Henrik, additional, Lieberman, Philip, additional, Lipworth, Brian, additional, Lodrup Carlsen, Karin C., additional, Lopes‐Pereira, Catarina, additional, Loureiro, Claudia C., additional, Louis, Renaud, additional, Mair, Alpana, additional, Mahboub, Bassam, additional, Makris, Michaël, additional, Malva, Joao, additional, Manning, Patrick, additional, Marshall, Gailen D., additional, Masjedi, Mohamed R., additional, Maspero, Jorge F., additional, Carreiro‐Martins, Pedro, additional, Makela, Mika, additional, Mathieu‐Dupas, Eve, additional, Maurer, Marcus, additional, De Manuel Keenoy, Esteban, additional, Melo‐Gomes, Elisabete, additional, Meltzer, Eli O., additional, Menditto, Enrica, additional, Mercier, Jacques, additional, Micheli, Yann, additional, Miculinic, Neven, additional, Mihaltan, Florin, additional, Milenkovic, Branislava, additional, Mitsias, Dimitirios I., additional, Moda, Giuliana, additional, Mogica‐Martinez, Maria‐Dolores, additional, Mohammad, Yousser, additional, Montefort, Steve, additional, Monti, Ricardo, additional, Morais‐Almeida, Mario, additional, Mösges, Ralph, additional, Münter, Lars, additional, Muraro, Antonella, additional, Murray, Ruth, additional, Naclerio, Robert, additional, Napoli, Luigi, additional, Namazova‐Baranova, Leyla, additional, Neffen, Hugo, additional, Nekam, Kristoff, additional, Neou, Angelo, additional, Nordlund, Björn, additional, Novellino, Ettore, additional, Nyembue, Dieudonné, additional, O'Hehir, Robyn, additional, Ohta, Ken, additional, Okubo, Kimi, additional, Onorato, Gabrielle L., additional, Orlando, Valentina, additional, Ouedraogo, Solange, additional, Palamarchuk, Julia, additional, Pali‐Schöll, Isabella, additional, Panzner, Peter, additional, Park, Hae‐Sim, additional, Passalacqua, Gianni, additional, Pépin, Jean‐Louis, additional, Paulino, Ema, additional, Pawankar, Ruby, additional, Phillips, Jim, additional, Picard, Robert, additional, Pinnock, Hilary, additional, Plavec, Davor, additional, Popov, Todor A., additional, Portejoie, Fabienne, additional, Price, David, additional, Prokopakis, Emmanuel P., additional, Psarros, Fotis, additional, Pugin, Benoit, additional, Puggioni, Francesca, additional, Quinones‐Delgado, Pablo, additional, Raciborski, Filip, additional, Rajabian‐Söderlund, Rojin, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Rivero‐Yeverino, Daniela, additional, Roberts, Graham, additional, Roche, Nicolas, additional, Rodriguez‐Zagal, Erendira, additional, Roller‐Wirnsberger, Regina E., additional, Rosario, Nelson, additional, Romano, Antonino, additional, Rottem, Menachem, additional, Ryan, Dermot, additional, Salimäki, Johanna, additional, Sanchez‐Borges, Mario M., additional, Sastre, Joaquin, additional, Scadding, Glenis K., additional, Scheire, Sophie, additional, Schmid‐Grendelmeier, Peter, additional, Schünemann, Holger J., additional, Sarquis Serpa, Faradiba, additional, Shamji, Mohamed, additional, Sisul, Juan‐Carlos, additional, Solé, Dirceu, additional, Somekh, David, additional, Sooronbaev, Talant, additional, Sova, Milan, additional, Spertini, François, additional, Spranger, Otto, additional, Stellato, Cristiana, additional, Stelmach, Rafael, additional, Thibaudon, Michel, additional, To, Teresa, additional, Toumi, Mondher, additional, Usmani, Omar, additional, Valero, Antonio A., additional, Valenta, Rudolph, additional, Valentin‐Rostan, Marylin, additional, Pereira, Marilyn Urrutia, additional, van der Kleij, Rianne, additional, Van Eerd, Michiel, additional, Vandenplas, Olivier, additional, Vasankari, Tuula, additional, Vaz Carneiro, Antonio, additional, Vezzani, Giorgio, additional, Viart, Frédéric, additional, Viegi, Giovanni, additional, Wallace, Dana, additional, Wagenmann, Martin, additional, Wang, De Yun, additional, Waserman, Susan, additional, Wickman, Magnus, additional, Williams, Dennis M., additional, Wong, Gary, additional, Wroczynski, Piotr, additional, Yiallouros, Panayiotis K., additional, Yusuf, Osman M., additional, Zar, Heather J., additional, Zeng, Stéphane, additional, Zernotti, Mario E., additional, Zhang, Luo, additional, Shan Zhong, Nan, additional, and Zidarn, Mihaela, additional
Published: 2020
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29. ARIA‐EAACI statement on asthma and COVID‐19 (June 2, 2020)

Author: Bousquet, Jean, primary, Jutel, Marek, additional, Akdis, Cezmi A., additional, Klimek, Ludger, additional, Pfaar, Oliver, additional, Nadeau, Kari C., additional, Eiwegger, Thomas, additional, Bedbrook, Anna, additional, Ansotegui, Ignacio J., additional, Anto, Josep M., additional, Bachert, Claus, additional, Bateman, Eric D., additional, Bennoor, Kazi S., additional, Berghea, Elena Camelia, additional, Bergmann, Karl‐Christian, additional, Blain, Hubert, additional, Bonini, Mateo, additional, Bosnic‐Anticevich, Sinthia, additional, Boulet, Louis‐Philippe, additional, Brussino, Luisa, additional, Buhl, Roland, additional, Camargos, Paulo, additional, Canonica, Giorgio Walter, additional, Cardona, Victoria, additional, Casale, Thomas, additional, Chinthrajah, Sharon, additional, Akdis, Mübeccel, additional, Chivato, Tomas, additional, Christoff, George, additional, Cruz, Alvaro A., additional, Czarlewski, Wienczyslawa, additional, Del Giacco, Stefano, additional, Du, Hui, additional, El‐Gamal, Yehia, additional, Fokkens, Wytske J., additional, Fonseca, Joao A., additional, Gao, Yadong, additional, Gaga, Mina, additional, Gemicioglu, Bilun, additional, Gotua, Maia, additional, Haahtela, Tari, additional, Halpin, David, additional, Hamelmann, Eckard, additional, Hoffmann‐Sommergruber, Karin, additional, Humbert, Marc, additional, Ilina, Nataliya, additional, Ivancevich, Juan‐Carlos, additional, Joos, Guy, additional, Khaitov, Musa, additional, Kirenga, Bruce, additional, Knol, Edward F., additional, Ko, Fanny W., additional, Koskinen, Seppo, additional, Kowalski, Marek L., additional, Kraxner, Helga, additional, Kudlay, Dmitry, additional, Kuna, Piotr, additional, Kupczyk, Maciej, additional, Kvedariene, Violeta, additional, Abdul Latiff, Amir H., additional, Le, Lan T., additional, Levin, Michael, additional, Larenas‐Linnemann, Desiree, additional, Louis, Renaud, additional, Masjedi, Mohammad R., additional, Melén, Erik, additional, Mihaltan, Florin, additional, Milenkovic, Branislava, additional, Mohammad, Yousser, additional, Morais‐Almeida, Mario, additional, Mullol, Joaquim, additional, Namazova, Leyla, additional, Neffen, Hugo, additional, Nunes, Elisabete, additional, O’Byrne, Paul, additional, O’Hehir, Robyn, additional, O’Mahony, Liam, additional, Ohta, Ken, additional, Okamoto, Yoshitaka, additional, Onorato, Gabrielle L., additional, Panzner, Petr, additional, Papadopoulos, Nikos G., additional, Passalacqua, Gianni, additional, Patella, Vincenzo, additional, Pawankar, Ruby, additional, Pham‐Thi, Nhân, additional, Pigearias, Bernard, additional, Popov, Todor A., additional, Puggioni, Francesca, additional, Regateiro, Frederico S., additional, Rolla, Giovanni, additional, Rottem, Menachem, additional, Samolinski, Boleslaw, additional, Sastre, Joaquin, additional, Schwarze, Jurgen, additional, Sheikh, Aziz, additional, Scichilone, Nicola, additional, Soto‐Quiros, Manuel, additional, Soto‐Martinez, Manuel, additional, Sova, Milan, additional, Nicola, Stefania, additional, Stelmach, Rafael, additional, Suppli‐Ulrik, Charlotte, additional, Taborda‐Barata, Luis, additional, To, Teresa, additional, Tomazic, Peter‐Valentin, additional, Toppila‐Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Usmani, Omar, additional, Valiulis, Arunas, additional, Ventura, Maria Teresa, additional, Viegi, Giovanni, additional, Vontetsianos, Theodor, additional, Wang, De Yun, additional, Williams, Sian, additional, Wong, Gary W. K., additional, Yorgancioglu, Arzu, additional, Zernotti, Mario, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, and Agache, Ioana, additional
Published: 2020
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30. Viola duet: A rare case of double sensitization to contact allergens in a professional musician

Author: Alves, Pedro B., primary, Todo‐Bom, Ana, additional, and Regateiro, Frederico S., additional
Published: 2020
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31. Diagnostic testing for penicillin allergy: A survey of practices and cost perceptions

Author: Sousa‐Pinto, Bernardo, primary, Blumenthal, Kimberly G., additional, Macy, Eric, additional, Bavbek, Sevim, additional, Benić, Mirjana Stanić, additional, Alves‐Correia, Magna, additional, Dursun, Adile Berna, additional, Jerschow, Elina, additional, Kong‐Cardoso, Bárbara, additional, Kopač, Peter, additional, Lefèvre, Sébastien, additional, Lombardo, Carla, additional, Marraccini, Paolo, additional, Moral, Luis, additional, Norton, Allison Eaddy, additional, Petrişor, Cristina, additional, Poziomkowska‐Gęsicka, Iwona, additional, Regateiro, Frederico S., additional, Santos, Natacha, additional, Saretta, Francesca, additional, Turkalj, Mirjana, additional, Veličković, Jelena, additional, Wöhrl, Stefan, additional, Yazicioglu, Mehtap, additional, Zidarn, Mihaela, additional, Pereira, Mariana, additional, Rebelo‐Gomes, Eva, additional, Pereira, Ana Margarida, additional, Delgado, Luís, additional, and Almeida Fonseca, João, additional
Published: 2019
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32. Drug reaction with eosinophilia and systemic symptoms caused by spironolactone: Case report

Author: Fernandes, Rosa-Anita, primary, Regateiro, Frederico S., additional, Faria, Emília, additional, Martinho, António, additional, Gonçalo, Margarida, additional, and Todo-Bom, Ana, additional
Published: 2018
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33. Activation rather than Foxp3 expression determines that TGF‐β‐induced regulatory T cells out‐compete naïve T cells in dendritic cell clustering

Author: Chen, Ye, primary, Adams, Elizabeth, additional, Regateiro, Frederico S., additional, Vaux, David J., additional, Betz, Alexander G., additional, Andersen, Kristian G., additional, Waldmann, Herman, additional, and Howie, Duncan, additional
Published: 2012
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34. Generation of anti‐inflammatory adenosine byleukocytes is regulated by TGF‐β

Author: Regateiro, Frederico S., primary, Howie, Duncan, additional, Nolan, Kathleen F., additional, Agorogiannis, Eleftherios I., additional, Greaves, David R., additional, Cobbold, Stephen P., additional, and Waldmann, Herman, additional
Published: 2011
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35. Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link

Author: Cobbold, Stephen P., primary, Adams, Elizabeth, additional, Nolan, Kathleen F., additional, Regateiro, Frederico S., additional, and Waldmann, Herman, additional
Published: 2010
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36. Concurrent validity, cut-offs and ability to change of patient-reported outcome measures for rhinitis and asthma in MASK-air ® .

Author: Bousquet J, Sousa-Pinto B, Anto JM, Bedbrook A, Czarlewski W, Ansotegui IJ, Bergmann KC, Braido F, Brussino L, Cecchi L, Loureiro CC, Cruz AA, Devillier P, Fiocchi A, Gemicioglu B, Haahtela T, Ivancevich JC, Klimek L, Kulus M, Kuna P, Kupczyk M, Kvedariene V, Larenas-Linnemann DE, Louis G, Louis R, Makris M, Morais-Almeida M, Niedoszytko M, Ohta K, Ollert M, Papadopoulos N, Patella V, Pétré B, Pfaar O, Puggioni F, Quirce S, Regateiro FS, Roche N, Rouadi PW, Samolinski B, Sastre J, Schleich F, Scichilone N, Taborda-Barata L, Toppila-Salmi S, Valiulis A, Vardaloglu Koyuncu I, Ventura MT, Yorgancioglu A, Fonseca JA, and Zuberbier T
Abstract: Patient-reported outcome measures (PROMs) are used to assess a patient's health status at a particular point in time. They are essential in the development of person-centred care. This paper reviews studies performed on PROMs for assessing AR and asthma control, in particular VAS scales that are included in the app MASK-air ® (Mobile Airways Sentinel networK) for asthma and rhinitis. VASs were initially developed on paper and pencil and tested for their criterion validity, cut-offs and responsiveness. Then, a multicentric, multinational, double-blind, placebo-controlled, randomised control trial (DB-PC-RCT) using an electronic VAS form was carried out. Finally, with the development of MASK-air ® in 2015, previously validated VAS questions were adapted to the digital format and further methodologic evaluations were performed. VAS for asthma, rhinitis, conjunctivitis, work and EQ-5D are included in the app. Additionally, two control-medication scores for allergic symptoms of asthma (e-DASTHMA) were validated for their criterion validity, cut-offs and responsiveness., (© 2024 The Author(s). Clinical and Translational Allergy published by John Wiley & Sons Ltd on behalf of European Academy of Allergy and Clinical Immunology.)
Published: 2024
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37. Relevance of individual bronchial symptoms for asthma diagnosis and control in patients with rhinitis: A MASK-air study.

Author: Sousa-Pinto B, Louis G, Vieira RJ, Czarlewski W, Anto JM, Amaral R, Sá-Sousa A, Brussino L, Canonica GW, Loureiro CC, Cruz AA, Gemicioglu B, Haahtela T, Kupczyk M, Kvedariene V, Larenas-Linnemann DE, Pham-Thi N, Puggioni F, Regateiro FS, Romantowski J, Sastre J, Scichilone N, Taborda-Barata L, Ventura MT, Agache I, Bedbrook A, Benfante A, Bergmann KC, Bosnic-Anticevich S, Bonini M, Boulet LP, Brusselle G, Buhl R, Cecchi L, Charpin D, Costa EM, Del Giacco S, Jutel M, Klimek L, Kuna P, Laune D, Makela M, Morais-Almeida M, Nadif R, Niedoszytko M, Papadopoulos NG, Papi A, Pfaar O, Rivero-Yeverino D, Roche N, Samolinski B, Shamji MH, Sheikh A, Ulrik CS, Usmani OS, Valiulis A, Yorgancioglu A, Zuberbier T, Fonseca JA, Pétré B, Louis R, and Bousquet J
Abstract: Rationale: It is unclear how each individual asthma symptom is associated with asthma diagnosis or control., Objectives: To assess the performance of individual asthma symptoms in the identification of patients with asthma and their association with asthma control., Methods: In this cross-sectional study, we assessed real-world data using the MASK-air ® app. We compared the frequency of occurrence of five asthma symptoms (dyspnea, wheezing, chest tightness, fatigue and night symptoms, as assessed by the Control of Allergic Rhinitis and Asthma Test [CARAT] questionnaire) in patients with probable, possible or no current asthma. We calculated the sensitivity, specificity and predictive values of each symptom, and assessed the association between each symptom and asthma control (measured using the e-DASTHMA score). Results were validated in a sample of patients with a physician-established diagnosis of asthma., Measurement and Main Results: We included 951 patients (2153 CARAT assessments), with 468 having probable asthma, 166 possible asthma and 317 no evidence of asthma. Wheezing displayed the highest specificity (90.5%) and positive predictive value (90.8%). In patients with probable asthma, dyspnea and chest tightness were more strongly associated with asthma control than other symptoms. Dyspnea was the symptom with the highest sensitivity (76.1%) and the one consistently associated with the control of asthma as assessed by e-DASTHMA. Consistent results were observed when assessing patients with a physician-made diagnosis of asthma., Conclusions: Wheezing and chest tightness were the asthma symptoms with the highest specificity for asthma diagnosis, while dyspnea displayed the highest sensitivity and strongest association with asthma control., (© 2024 The Authors. Clinical and Translational Allergy published by John Wiley & Sons Ltd on behalf of European Academy of Allergy and Clinical Immunology.)
Published: 2024
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38. The Portuguese Severe Asthma Registry: Development, Features, and Data Sharing Policies.

Author: Sá-Sousa A, Fonseca JA, Pereira AM, Ferreira A, Arrobas A, Mendes A, Drummond M, Videira W, Costa T, Farinha P, Soares J, Rocha P, Todo-Bom A, Sokolova A, Costa A, Fernandes B, Chaves Loureiro C, Longo C, Pardal C, Costa C, Cruz C, Loureiro CC, Lopes C, Mesquita D, Faria E, Magalhães E, Menezes F, Todo-Bom F, Carvalho F, Regateiro FS, Falcão H, Fernandes I, Gaspar-Marques J, Viana J, Ferreira J, Silva JM, Simão L, Almeida L, Fernandes L, Ferreira L, van Zeller M, Quaresma M, Castanho M, André N, Cortesão N, Leiria-Pinto P, Pinto P, Rosa P, Carreiro-Martins P, Gerardo R, Silva R, Lucas S, Almeida T, and Calvo T
Subjects: Child, Consensus, Data Collection statistics & numerical data, Databases, Factual statistics & numerical data, Electronic Health Records statistics & numerical data, Female, Humans, Information Dissemination methods, Male, Portugal epidemiology, Quality of Life, Asthma epidemiology, Registries statistics & numerical data
Abstract: The Portuguese Severe Asthma Registry ( Registo de Asma Grave Portugal, RAG) was developed by an open collaborative network of asthma specialists. RAG collects data from adults and pediatric severe asthma patients that despite treatment optimization and adequate management of comorbidities require step 4/5 treatment according to GINA recommendations. In this paper, we describe the development and implementation of RAG, its features, and data sharing policies. The contents and structure of RAG were defined in a multistep consensus process. A pilot version was pretested and iteratively improved. The selection of data elements for RAG considered other severe asthma registries, aiming at characterizing the patient's clinical status whilst avoiding overloading the standard workflow of the clinical appointment. Features of RAG include automatic assessment of eligibility, easy data input, and exportable data in natural language that can be pasted directly in patients' electronic health record and security features to enable data sharing (among researchers and with other international databases) without compromising patients' confidentiality. RAG is a national web-based disease registry of severe asthma patients, available at asmagrave.pt . It allows prospective clinical data collection, promotes standardized care and collaborative clinical research, and may contribute to inform evidence-based healthcare policies for severe asthma.
Published: 2018
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