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Your search keyword '"Ricciutelli, Massimo"' showing total 25 results
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25 results on '"Ricciutelli, Massimo"'

1. Faecal proteome in clinically healthy dogs and cats: Findings in pooled faeces from 10 cats and 10 dogs

Author

Cerquetella, Matteo, primary, Marchegiani, Andrea, additional, Mangiaterra, Sara, additional, Rossi, Giacomo, additional, Gavazza, Alessandra, additional, Tesei, Beniamino, additional, Spaterna, Andrea, additional, Sagratini, Gianni, additional, Ricciutelli, Massimo, additional, Polzonetti, Valeria, additional, Pucciarelli, Stefania, additional, and Vincenzetti, Silvia, additional

Published
2021
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4. Insights into the GTP‐dependent allosteric control of c‐di‐GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa

Author

Mantoni, Federico, primary, Paiardini, Alessandro, additional, Brunotti, Paolo, additional, D'Angelo, Cecilia, additional, Cervoni, Laura, additional, Paone, Alessio, additional, Cappellacci, Loredana, additional, Petrelli, Riccardo, additional, Ricciutelli, Massimo, additional, Leoni, Livia, additional, Rampioni, Giordano, additional, Arcovito, Alessandro, additional, Rinaldo, Serena, additional, Cutruzzolà, Francesca, additional, and Giardina, Giorgio, additional

Published
2018
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6. Evaluation of the hypocholesterolemic effect and prebiotic activity of a lentil (Lens culinarisMedik) extract

Author

Micioni Di Bonaventura, Maria Vittoria, primary, Cecchini, Cinzia, additional, Vila-Donat, Pilar, additional, Caprioli, Giovanni, additional, Cifani, Carlo, additional, Coman, Maria Magdalena, additional, Cresci, Alberto, additional, Fiorini, Dennis, additional, Ricciutelli, Massimo, additional, Silvi, Stefania, additional, Vittori, Sauro, additional, and Sagratini, Gianni, additional

Published
2017
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10. Central Nervous System Activities of Hypericum origanifolium Extract via GABAergic and Opioidergic Mechanisms

Author

Yaşar, Ş. N., Can, Ö. D., Öztürk, N., Sagratini, Gianni, Ricciutelli, Massimo, Vittori, Sauro, Maggi, Filippo, Anadolu Üniversitesi, Eczacılık Fakültesi, Farmakoloji Anabilim Dalı, Can, Özgür Devrim, and Öztürk, Nilgün

Subjects
Antinociceptive, Anxiolytic, Rutin, Hypericum Origanifolium, Antidepressant, Chlorogenic Acid
Abstract

WOS: 000320114500013, PubMed ID: 22903405, Pharmacological effects of hydroalcoholic extract prepared from Hypericum origanifolium Willd. (Guttiferae) on behavioral parameters and pain perceptions of mice were investigated in this study. Depression, anxiety, spontaneous locomotor activity, and motor coordination parameters of mice were assessed by modified forced swimming, hole board, activity cage, and rota-rod tests, respectively. In addition, antinociceptive effect was evaluated by performing hot-plate, tail-clip, and formalin tests. Reboxetine (20mg/kg), diazepam (1mg/kg), and morphine (10mg/kg) were used as reference antidepressant, anxiolytic, and analgesic drugs, respectively. Phytochemical analyses exhibited that chlorogenic acid (2317.12ppm) and rutin (2108.79ppm) were the main phenolic compounds in the H.origanifolium extract. The extract (50, 100, and 250mg/kg) induced significant antidepressant, anxiolytic, and antinociceptive activities following the acute administrations. Anxiolytic effect was antagonized by flumazenil (a benzodiazepine receptor antagonist, 2.5mg/kg, i.p.) pre-treatment, which indicated the participation of GABA(A)-benzodiazepine receptor complex in the activity. Moreover, centrally and peripherally mediated antinociception reversed by naloxone (a non-selective opioid receptor antagonist, 5mg/kg, i.p.) pre-treatment, indicating the involvement of opioid system in the pharmacological action. These findings are the first to indicate the pharmacological effects of the H.origanifolium extract on the emotional state and pain perceptions of mice. Copyright (c) 2012 John Wiley & Sons, Ltd.

Published
2013

11. Essential oil chemotypification and secretory structures of the neglected vegetable Smyrnium olusatrum L. (Apiaceae) growing in central Italy

Author

Maggi, Filippo, primary, Papa, Fabrizio, additional, Giuliani, Claudia, additional, Maleci Bini, Laura, additional, Venditti, Alessandro, additional, Bianco, Armandodoriano, additional, Nicoletti, Marcello, additional, Iannarelli, Romilde, additional, Caprioli, Giovanni, additional, Sagratini, Gianni, additional, Cortese, Manuela, additional, Ricciutelli, Massimo, additional, and Vittori, Sauro, additional

Published
2014
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18. New L‐Dopa Codrugs as Potential Antiparkinson Agents

Author

Sozio, Piera, primary, Iannitelli, Antonio, additional, Cerasa, Laura Serafina, additional, Cacciatore, Ivana, additional, Cornacchia, Catia, additional, Giorgioni, Gianfabio, additional, Ricciutelli, Massimo, additional, Nasuti, Cinzia, additional, Cantalamessa, Franco, additional, and Di Stefano, Antonio, additional

Published
2008
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24. Development and application of a UHPLC-MS/MS method for the simultaneous determination of 17 steroidal hormones in equine serum.

Author

Genangeli M, Caprioli G, Cortese M, Laus F, Matteucci M, Petrelli R, Ricciutelli M, Sagratini G, Sartori S, and Vittori S

Subjects
Animals, Chromatography, High Pressure Liquid methods, Doping in Sports, Female, Limit of Detection, Male, Metabolome, Substance Abuse Detection methods, Tandem Mass Spectrometry methods, Horses blood, Steroids blood
Abstract

A new, fast and simple analytical method that is able to identify and quantify simultaneously 17 steroid hormones and metabolites (pregnenolone, 17-OH-pregnenolone, progesterone, 17-OH-progesterone, androsterone, androstenedione, dehydroepiandrosterone, dehydroepiandrosterone sulfate, testosterone, cortisol, corticosterone, aldosterone, 11-deoxycortisol, 11-deoxycorticosterone, dihydrotestosterone, estrone and estradiol) has been developed in equine serum using the ultra-high-performance liquid chromatography-tandem mass spectrometry technique. A total of 400 µl of sample was deproteinized with 1000 µl of acetonitrile, evaporated, restored with 50 µl of a solution of 25% methanol and injected in ultra-high-performance liquid chromatography-tandem mass spectrometry triple quadrupole. The recovery percentage obtained by spiking the matrix at two different concentrations with a standard mixture of steroid hormones was in all cases higher than 85.60% and with the percentage of coefficient of variation lower than 8.37%. The range of the correlation coefficients of the calibration curves of the analyzed compounds was 0.9922-0.9986, and the limits of detection and limits of quantification were in the range of 0.002-2 and 0.0055-5.5 ng ml -1 , respectively. The detected limit of quantification for testosterone (i.e. 50 pg ml -1 ) is twofold lower with respect to its threshold admitted in geldings plasma (100 pg ml -1 free testosterone). The high sensitivity and the quantitative aspect of the method permitted to detect most of the steroids in equine serum. Once validated, the method was used to quantify 17 steroid hormones in mare, stallion and gelding serum samples. The main steroids detected were corticosterone (range 37.25-51.26 ng ml -1 ) and cortisol (range 32.57-52.24 ng ml -1 ), followed by 17-OH-pregnenolone, dihydrotestosterone and pregnenolone. Copyright © 2016 John Wiley & Sons, Ltd., (Copyright © 2016 John Wiley & Sons, Ltd.)

Published
2017
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25. Central nervous system activities of Hypericum origanifolium extract via GABAergic and opioidergic mechanisms.

Author

Yaşar SN, Can OD, Oztürk N, Sagratini G, Ricciutelli M, Vittori S, and Maggi F

Subjects
Animals, Behavior, Animal drug effects, Chlorogenic Acid analysis, Male, Mice, Pain Perception drug effects, Plant Extracts chemistry, Rutin analysis, Analgesics pharmacology, Anti-Anxiety Agents pharmacology, Antidepressive Agents pharmacology, Central Nervous System drug effects, Hypericum chemistry, Plant Extracts pharmacology
Abstract

Pharmacological effects of hydroalcoholic extract prepared from Hypericum origanifolium Willd. (Guttiferae) on behavioral parameters and pain perceptions of mice were investigated in this study. Depression, anxiety, spontaneous locomotor activity, and motor coordination parameters of mice were assessed by modified forced swimming, hole board, activity cage, and rota-rod tests, respectively. In addition, antinociceptive effect was evaluated by performing hot-plate, tail-clip, and formalin tests. Reboxetine (20 mg/kg), diazepam (1 mg/kg), and morphine (10 mg/kg) were used as reference antidepressant, anxiolytic, and analgesic drugs, respectively. Phytochemical analyses exhibited that chlorogenic acid (2317.12 ppm) and rutin (2108.79 ppm) were the main phenolic compounds in the H. origanifolium extract. The extract (50, 100, and 250 mg/kg) induced significant antidepressant, anxiolytic, and antinociceptive activities following the acute administrations. Anxiolytic effect was antagonized by flumazenil (a benzodiazepine receptor antagonist, 2.5 mg/kg, i.p.) pre-treatment, which indicated the participation of GABA(A)-benzodiazepine receptor complex in the activity. Moreover, centrally and peripherally mediated antinociception reversed by naloxone (a non-selective opioid receptor antagonist, 5 mg/kg, i.p.) pre-treatment, indicating the involvement of opioid system in the pharmacological action. These findings are the first to indicate the pharmacological effects of the H. origanifolium extract on the emotional state and pain perceptions of mice., (Copyright © 2012 John Wiley & Sons, Ltd.)

Published
2013
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