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Your search keyword '"Ruponen, Marika"' showing total 11 results
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11 results on '"Ruponen, Marika"'

3. Electrical synapses interconnecting axons in the optic nerve head–a novel model of optic nerve function

Author

Pietrucha‐Dutczak, Marita, primary, Akhtar, Saeed, additional, Liu, Xiaonan, additional, Podracka, Lucia, additional, Toropainen, Elisa, additional, Alkanaan, Aljoharah, additional, Ruponen, Marika, additional, Urtti, Arto, additional, Varjosalo, Markku, additional, Kaarniranta, Kai, additional, Lewin‐Kowalik, Joanna, additional, and Smedowski, Adrian, additional

Published
2019
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5. Electrical synapses interconnecting axons revealed in the optic nerve head – a novel model of gap junctions’ involvement in optic nerve function

Author

Smedowski, Adrian, primary, Akhtar, Saeed, additional, Liu, Xiaonan, additional, Pietrucha‐Dutczak, Marita, additional, Podracka, Lucia, additional, Toropainen, Elisa, additional, Alkanaan, Aljoharah, additional, Ruponen, Marika, additional, Urtti, Arto, additional, Varjosalo, Markku, additional, Kaarniranta, Kai, additional, and Lewin‐Kowalik, Joanna, additional

Published
2019
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11. Inhibition activity of wild berry juice fractions against Streptococcus pneumoniae binding to human bronchial cells.

Author

Huttunen S, Toivanen M, Arkko S, Ruponen M, and Tikkanen-Kaukanen C

Subjects
Anti-Bacterial Agents isolation & purification, Bronchi cytology, Cell Line, Chemical Fractionation, Fruit chemistry, Humans, Plant Preparations chemistry, Plant Preparations isolation & purification, Streptococcus pneumoniae physiology, Anti-Bacterial Agents pharmacology, Bacterial Adhesion drug effects, Beverages, Ericaceae chemistry, Plant Preparations pharmacology, Streptococcus pneumoniae drug effects, Vaccinium chemistry
Abstract

Bacterial adhesion to the cell surface is a crucial step before infection can take place. Inhibition of bacterial binding offers a novel preventive approach against infections. Cranberry (Vaccinium macrocarpon Ait.) juice has been found to have antiadhesive activity against different bacteria. Streptococcus pneumoniae is an important pathogen and the most common cause for pneumonia, meningitis, and otitis media. In this study the inhibitory activity of cranberry (Vaccinium oxycoccos L.), bilberry (Vaccinium myrtillus L.) and crowberry (Empetrum nigrum and Empetrum hermaphroditum L.) juice fractions against pneumococcal binding was tested using human bronchial cells (Calu-3) as an adhesion model. In addition, the antimicrobial activity of the berry juice fractions was tested. It was found that the studied berry juice fractions had antiadhesion activity and cranberry juice was the most active. The adhesion inhibition activity of cranberry juice was nearly 90% at a concentration of 8.7 mg/g of soluble solids. The antimicrobial activity of the studied berry juice fractions was found to be remarkable; pneumococcal growth was inhibited totally at a concentration of ∼86 mg/g. Both antiadhesion and antimicrobial activities were reduced after solid-phase extraction of the berry juices, which may suggest molecular synergistic effects of the berry juice molecules against S. pneumoniae. The findings indicate that cranberry, bilberry and crowberry juices have potential against pneumococcal infections., (Copyright © 2010 John Wiley & Sons, Ltd.)

Published
2011
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