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Your search keyword '"Ruwald, Anne-Christine"' showing total 9 results
Start Over Author "Ruwald, Anne-Christine" Publisher wiley
9 results on '"Ruwald, Anne-Christine"'

1. Postimplantation ventricular ectopic burden and clinical outcomes in cardiac resynchronization therapy-defibrillator patients: a MADIT-CRT substudy

Author

Ruwald, Anne-Christine, primary, Aktas, Mehmet K., additional, Ruwald, Martin H., additional, Kutyifa, Valentina, additional, McNitt, Scott, additional, Jons, Christian, additional, Mittal, Suneet, additional, Steinberg, Jonathan S., additional, Daubert, James P., additional, Moss, Arthur J., additional, and Zareba, Wojciech, additional

Published
2017
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3. Validation of an automatic diagnosis of strict left bundle branch block criteria using 12-lead electrocardiograms

Author

Xia, Xiaojuan, primary, Ruwald, Anne-Christine, additional, Ruwald, Martin H., additional, Ugoeke, Nene, additional, Szepietowska, Barbara, additional, Kutyifa, Valentina, additional, Aktas, Mehmet K., additional, Thomsen, Poul Erik B., additional, Zareba, Wojciech, additional, Moss, Arthur J., additional, and Couderc, Jean-Philippe, additional

Published
2016
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9. The impact of co-morbidity burden on appropriate implantable cardioverter defibrillator therapy and all-cause mortality: insight from Danish nationwide clinical registers.

Author

Ruwald AC, Vinther M, Gislason GH, Johansen JB, Nielsen JC, Petersen HH, Riahi S, and Jons C

Subjects
Aged, Atrial Fibrillation epidemiology, Cerebrovascular Disorders epidemiology, Cohort Studies, Comorbidity, Death, Sudden, Cardiac epidemiology, Denmark epidemiology, Diabetes Mellitus epidemiology, Female, Humans, Liver Diseases epidemiology, Male, Mental Disorders epidemiology, Middle Aged, Neoplasms epidemiology, Peripheral Vascular Diseases epidemiology, Primary Prevention, Proportional Hazards Models, Pulmonary Disease, Chronic Obstructive epidemiology, Renal Insufficiency, Chronic epidemiology, Retrospective Studies, Secondary Prevention, Death, Sudden, Cardiac prevention & control, Defibrillators, Implantable, Registries
Abstract

Aims: In a nationwide cohort of primary (PP-ICD) and secondary prevention (SP-ICD) implantable cardioverter defibrillator (ICD) patients, we aimed to investigate the association between co-morbidity burden and risk of appropriate ICD therapy and mortality., Methods and Results: We identified all patients >18 years, implanted with first-time PP-ICD (n = 1873) or SP-ICD (n = 2461) in Denmark from 2007 to 2012. Co-morbidity was identified in administrative registers of hospitalization and drug prescription from pharmacies. Co-morbidity burden was defined as the number of pre-existing non-ICD indication-related co-morbidities including atrial fibrillation, diabetes, chronic obstructive pulmonary disease, chronic renal disease, liver disease, cancer, chronic psychiatric disease, and peripheral and/or cerebrovascular disease, and divided into four groups (co-morbidity burden 0, 1, 2, and ≥3). Through Cox models, we assessed the impact of co-morbidity burden on appropriate ICD therapy and mortality. Increasing co-morbidity burden was not associated with increased risk of appropriate therapy, irrespective of implant indication [all hazard ratios (HRs) 1.0-1.4, P = NS]. Using no co-morbidities as reference, increasing co-morbidity burden was associated with increased mortality risk in PP-ICD patients (co-morbidity burden 1, HR 2.1; comorbidity burden 2, HR 3.7; co-morbidity burden ≥3, HR 6.6) (all P < 0.001) and SP-ICD patients (co-morbidity burden 1, HR 2.2; co-morbidity burden 2, HR 3.8; co-morbidity burden ≥3, HR 5.8). With increasing co-morbidity burden, an increasing frequency of patients died without having utilized their device, with 72% PP-ICD and 45% SP-ICD patients with co-morbidity burden ≥3 dying without prior appropriate ICD therapy., Conclusion: Increasing co-morbidity burden was not associated with increased risk of appropriate ICD therapy. With increasing co-morbidity burden, mortality increased, and a higher proportion of patients died, without ever having utilized their device., (© 2016 The Authors. European Journal of Heart Failure © 2016 European Society of Cardiology.)

Published
2017
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