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Your search keyword '"Shi, Zhong-Li"' showing total 5 results
Start Over Author "Shi, Zhong-Li" Publisher wiley
5 results on '"Shi, Zhong-Li"'

1. Sophocarpine attenuates wear particle‐induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF‐κB signalling pathway in a rat model

Author

Zhou, Chen‐he, primary, Shi, Zhong‐li, additional, Meng, Jia‐hong, additional, Hu, Bin, additional, Zhao, Chen‐chen, additional, Yang, Yu‐te, additional, Yu, Wei, additional, Chen, Ze‐xin, additional, Heng, Boon Chin, additional, Parkman, Virginia‐Jeni Akila, additional, Jiang, Shuai, additional, Zhu, Han‐xiao, additional, Wu, Hao‐bo, additional, Shen, Wei‐liang, additional, and Yan, Shi‐gui, additional

Published
2018
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5. Effects of diallyl sulphide in chondrocyte and cartilage in experimental osteoarthritis in rabbit.

Author

Chen WP, Tang JL, Bao JP, Hu PF, Yu C, Shi ZL, and Wu LD

Subjects
Animals, Cartilage metabolism, Cells, Cultured, Chondrocytes metabolism, Collagen Type II metabolism, Disease Models, Animal, Female, Interleukin-1beta metabolism, Matrix Metalloproteinase 1 metabolism, Matrix Metalloproteinase 13 metabolism, Matrix Metalloproteinase 3 metabolism, RNA, Messenger metabolism, Rabbits, Allyl Compounds pharmacology, Cartilage drug effects, Chondrocytes drug effects, Osteoarthritis drug therapy, Sulfides pharmacology
Abstract

Diallyl sulphide (DAS) is known for its antioxidant, anticancer and detoxifying properties. The aim of this study was to investigate the effect of DAS on rabbit articular chondrocytes and cartilage in experimental osteoarthritis (OA) induced by anterior cruciate ligament transection (ACLT). DAS inhibited matrix metalloproteinase-1 (MMP-1), MMP-3 and MMP-13 expression in interleukin-1beta (IL-1β)-induced chondrocytes. In an in vivo study, DAS ameliorated cartilage degradation as assessed by morphological and histological examination. Messenger RNA expression of MMP-1, MMP-3, MMP-13 and IL-1β was inhibited by DAS in cartilage. In addition, DAS increased the collagen II level in cartilage. The results suggest that DAS may protect cartilage in the development of OA., (Copyright © 2010 John Wiley & Sons, Ltd.)

Published
2011
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