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45 results on '"Shyr, Yu"'

1. Comparative Treatment Outcomes for Idiopathic Subglottic Stenosis: 5‐Year Update

Author

Tierney, William S., primary, Huang, Li‐Ching, additional, Chen, Sheau‐Chiann, additional, Berry, Lynn D., additional, Anderson, Catherine, additional, Amin, Milan R., additional, Benninger, Michael S., additional, Blumin, Joel H., additional, Bock, Jonathan M., additional, Bryson, Paul C., additional, Castellanos, Paul F., additional, Clary, Matthew S., additional, Cohen, Seth M., additional, Crawley, Brianna K., additional, Dailey, Seth H., additional, Daniero, James J., additional, de Alarcon, Alessandro, additional, Donovan, Donald T., additional, Edell, Eric S., additional, Ekbom, Dale C., additional, Fink, Daniel S., additional, Franco, Ramon A., additional, Garrett, Catherine Gaelyn, additional, Guardiani, Elizabeth A., additional, Hillel, Alexander T., additional, Hoffman, Henry T., additional, Hogikyan, Norman D., additional, Howell, Rebecca J., additional, Johns, Michael M., additional, Kasperbauer, Jan L., additional, Khosla, Sid M., additional, Kinnard, Cheryl, additional, Kupfer, Robbi A., additional, Langerman, Alexander J., additional, Lentz, Robert J., additional, Lorenz, Robert R., additional, Lott, David G., additional, Makani, Samir S., additional, Maldonado, Fabien, additional, Matrka, Laura, additional, McWhorter, Andrew J., additional, Merati, Albert L., additional, Mori, Matthew, additional, Netterville, James L., additional, O'Dell, Karla, additional, Ongkasuwan, Julina, additional, Postma, Gregory N., additional, Reder, Lindsay S., additional, Rohde, Sarah L., additional, Richardson, Brent E., additional, Rickman, Otis B., additional, Rosen, Clark A., additional, Rohlfing, Matthew, additional, Rutter, Michael J., additional, Sandhu, Guri S., additional, Schindler, Joshua S., additional, Schneider, Glenn Todd, additional, Shah, Rupali N., additional, Sikora, Andrew G., additional, Sinard, Robert J., additional, Smith, Marshall E., additional, Smith, Libby J., additional, Soliman, Ahmed M. S., additional, Sveinsdóttir, Sigríður, additional, Veivers, David, additional, Verma, Sunil P., additional, Weinberger, Paul M., additional, Weissbrod, Philip A., additional, Wootten, Christopher T., additional, Shyr, Yu, additional, Francis, David O., additional, and Gelbard, Alexander, additional

Published
2023
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2. Endogenous sex hormones, aromatase activity and lung cancer risk in postmenopausal never‐smoking women

Author

Zhao, Yingya, primary, Gao, Yu‐Tang, additional, Zhang, Xianglan, additional, Rockwood, Alan L., additional, Kushnir, Mark M., additional, Cai, Qiuyin, additional, Wu, Jie, additional, Shi, Jiajun, additional, Lan, Qing, additional, Rothman, Nathaniel, additional, Shyr, Yu, additional, Shu, Xiao‐Ou, additional, Zheng, Wei, additional, and Yang, Gong, additional

Published
2022
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6. Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins

Author

Allen, Ryan M., primary, Zhao, Shilin, additional, Ramirez Solano, Marisol A., additional, Zhu, Wanying, additional, Michell, Danielle L., additional, Wang, Yuhuan, additional, Shyr, Yu, additional, Sethupathy, Praveen, additional, Linton, MacRae F., additional, Graf, Gregory A., additional, Sheng, Quanhu, additional, and Vickers, Kasey C., additional

Published
2018
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7. Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial)

Author

Galadanci, Najibah A., primary, Umar Abdullahi, Shehu, additional, Vance, Leah D., additional, Musa Tabari, Abdulkadir, additional, Ali, Shehi, additional, Belonwu, Raymond, additional, Salihu, Auwal, additional, Amal Galadanci, Aisha, additional, Wudil Jibir, Binta, additional, Bello-Manga, Halima, additional, Neville, Kathleen, additional, Kirkham, Fenella J., additional, Shyr, Yu, additional, Phillips, Sharon, additional, Covert, Brittany V., additional, Kassim, Adetola A., additional, Jordan, Lori C., additional, Aliyu, Muktar H., additional, and DeBaun, Michael R., additional

Published
2018
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8. Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial)

Author

Galadanci, Najibah A., primary, Umar Abdullahi, Shehu, additional, Vance, Leah D., additional, Musa Tabari, Abdulkadir, additional, Ali, Shehi, additional, Belonwu, Raymond, additional, Salihu, Auwal, additional, Amal Galadanci, Aisha, additional, Wudil Jibir, Binta, additional, Bello-Manga, Halima, additional, Neville, Kathleen, additional, Kirkham, Fenella J., additional, Shyr, Yu, additional, Phillips, Sharon, additional, Covert, Brittany V., additional, Kassim, Adetola A., additional, Jordan, Lori C., additional, Aliyu, Muktar H., additional, and DeBaun, Michael R., additional

Published
2017
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9. Multisite external validation of a risk prediction model for the diagnosis of blood stream infections in febrile pediatric oncology patients without severe neutropenia

Author

Esbenshade, Adam J., primary, Zhao, Zhiguo, additional, Aftandilian, Catherine, additional, Saab, Raya, additional, Wattier, Rachel L., additional, Beauchemin, Melissa, additional, Miller, Tamara P., additional, Wilkes, Jennifer J., additional, Kelly, Michael J., additional, Fernbach, Alison, additional, Jeng, Michael, additional, Schwartz, Cindy L., additional, Dvorak, Christopher C., additional, Shyr, Yu, additional, Moons, Karl G.M., additional, Sulis, Maria-Luisa, additional, and Friedman, Debra L., additional

Published
2017
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11. Primary stroke prevention in Nigerian children with sickle cell disease (SPIN): Challenges of conducting a feasibility trial

Author

Galadanci, Najibah A., primary, Abdullahi, Shehu U., additional, Tabari, Musa A., additional, Abubakar, Shehi, additional, Belonwu, Raymond, additional, Salihu, Auwal, additional, Neville, Kathleen, additional, Kirkham, Fenella, additional, Inusa, Baba, additional, Shyr, Yu, additional, Phillips, Sharon, additional, Kassim, Adetola A., additional, Jordan, Lori C., additional, Aliyu, Muktar H., additional, Covert, Brittany V., additional, and DeBaun, Michael R., additional

Published
2014
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13. Phase II trial of sorafenib and erlotinib in advanced pancreatic cancer

Author

Cardin, Dana B., primary, Goff, Laura, additional, Li, Chung‐I, additional, Shyr, Yu, additional, Winkler, Charles, additional, DeVore, Russell, additional, Schlabach, Larry, additional, Holloway, Melanie, additional, McClanahan, Pam, additional, Meyer, Krista, additional, Grigorieva, Julia, additional, Berlin, Jordan, additional, and Chan, Emily, additional

Published
2014
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26. Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma

Author

Shinohara, Eric T., primary, Gonzalez, Adriana, additional, Massion, Pierre P., additional, Chen, Heidi, additional, Li, Ming, additional, Freyer, Andrea S., additional, Olson, Sandra J., additional, Andersen, Jeremiah J., additional, Shyr, Yu, additional, Carbone, David P., additional, Johnson, David H., additional, Hallahan, Dennis E., additional, and Lu, Bo, additional

Published
2005
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27. Gene expression profile analysis of mouse colon embryonic development

Author

Park, Young-Kyu, primary, Franklin, Jeffrey L., additional, Settle, Stephen H., additional, Levy, Shawn E., additional, Chung, Eunkyung, additional, Jeyakumar, Loice H., additional, Shyr, Yu, additional, Washington, Mary Kay, additional, Whitehead, Robert H., additional, Aronow, Bruce J., additional, and Coffey, Robert J., additional

Published
2005
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44. Altered expression of nuclear and cytoplasmic histone H1 in pulmonary artery and pulmonary artery smooth muscle cells in patients with IPAH.

Author

Talati M, Seeley E, Ihida-Stansbury K, Delisser H, McDonald H, Ye F, Zhang X, Shyr Y, Caprioli R, and Meyrick B

Abstract

The pathogenesis of idiopathic pulmonary hypertension is poorly understood. This paper utilized histology-based Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS) to identify as-yet unknown proteins that may be associated with the structural changes in the pulmonary arterial walls of patients with IPAH. The technology identified significant increases in two fragments of histone H1 in the IPAH cases compared to controls. This finding was further examined using immunofluorescence techniques applied to sections from IPAH and control pulmonary arteries. In addition, cultured pulmonary artery smooth muscle cells (PASMCs) were utilized for Western analysis of histone H1 and importin β and importin 7, immunoprecipitation and assessment of nucleosomal repeat length (NRL). Immunofluorescence techniques revealed that nuclear expression of histone H1 was decreased and the chromatin was less compact in the IPAH cases than in the controls; furthermore, some cases showed a marked increase in cytoplasmic histone H1 expression. Using nuclear and cytoplasmic fractions of cultured PASMCs, we confirmed the reduction in histone H1 in the nucleus and an increase in the cytoplasm in IPAH cells compared to controls. Immunoprecipitation demonstrated a decreased association of histone H1 with importin β while importin 7 was unchanged in the IPAH cells compared to controls. The assessment of NRL revealed that the distance between nucleosomes was increased by ~20 bp in IPAH compared to controls. We conclude that at least two factors contribute to the reduction in nuclear histone H1-fragmentation of the protein and decreased import of histone H1 into the nucleus by importins. We further suggest that the decreased nuclear H1 contributes the less compact nucleosomal pattern in IPAH and this, in turn, contributes to the increase in NRL.

Published
2012
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45. Increased resting energy expenditure in patients with end-stage renal disease.

Author

Neyra R, Chen KY, Sun M, Shyr Y, Hakim RM, and Ikizler TA

Subjects
Blood Proteins analysis, Body Composition physiology, Catecholamines blood, Cross-Sectional Studies, Diet Records, Disease Progression, Electric Impedance, Female, Humans, Male, Middle Aged, Regression Analysis, Rest physiology, Energy Metabolism physiology, Kidney Failure, Chronic metabolism
Abstract

Background: Protein-calorie malnutrition is a significant problem for patients with end-stage renal disease. Increased resting energy expenditure may be an important contributing factor. We postulate that resting energy expen diture in the different stages of renal disease and treatments may be different., Methods: Resting energy expenditure was measured using a whole-room indirect calorimeter (metabolic chamber) along with nutritional parameters and body composition after 12-hour fasting in 15 patients with advanced chronic renal failure patients, 15 patients on chronic hemodialysis, and 10 patients on peritoneal dialysis. Patients on hemodialysis were assessed on a non-dialysis day. A 2-day dietary recall was used to assess energy intake., Results: Resting energy expenditure, adjusted for fat-free mass, was similar in patients on hemodialysis and peritoneal dialysis but significantly higher than in patients with chronic renal failure (p < .05). Resting energy expenditure in all patients were generally higher (10% to 20%) than predicted values using standard equations derived in normal and obese populations, whereas daily energy intake was less (26% to 34%) than energy expenditure for all groups, adjusted for light daily activity., Conclusions: End-stage renal disease patients displayed increases in resting energy expenditure over the predicted values derived using normal populations. Resting energy expenditure was significantly higher in patients receiving dialysis, regardless of the modality, than patients with chronic renal failure. Daily energy intake was substantially less than required in all patient groups studied, suggesting that patients with renal failure could develop protein-calorie malnutrition because of increased resting energy expenditure, which is exacerbated by dialysis.

Published
2003
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