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35 results on '"Simmonds, Monique S. J."'

5. Biodiversity and patents: Overview of plants and fungi covered by patents

Author

Simmonds, Monique S. J., primary, Fang, Rui, additional, Wyatt, Lilybelle, additional, Bell, Elizabeth, additional, Allkin, Bob, additional, Forest, Felix, additional, Wynberg, Rachel, additional, Silva, Manuela, additional, Zhang, Ben Gang, additional, Shi Liu, Jiu, additional, Dong Qi, Yao, additional, and Demissew, Sebsebe, additional

Published
2020
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6. International collaboration between collections‐based institutes for halting biodiversity loss and unlocking the useful properties of plants and fungi

Author

Pearce, Timothy R., primary, Antonelli, Alexandre, additional, Brearley, Francis Q., additional, Couch, Charlotte, additional, Campostrini Forzza, Rafaela, additional, Gonçalves, Susana C., additional, Magassouba, Sékou, additional, Morim, Marli P., additional, Mueller, Gregory M., additional, Nic Lughadha, Eimear, additional, Obreza, Matija, additional, Sharrock, Suzanne, additional, Simmonds, Monique S. J., additional, Tambam, Beri Bonglim, additional, Utteridge, Timothy M. A., additional, and Breman, Elinor, additional

Published
2020
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7. Molecules from nature: Reconciling biodiversity conservation and global healthcare imperatives for sustainable use of medicinal plants and fungi

Author

Howes, Melanie‐Jayne R., primary, Quave, Cassandra L., additional, Collemare, Jérôme, additional, Tatsis, Evangelos C., additional, Twilley, Danielle, additional, Lulekal, Ermias, additional, Farlow, Andrew, additional, Li, Liping, additional, Cazar, María‐Elena, additional, Leaman, Danna J., additional, Prescott, Thomas A. K., additional, Milliken, William, additional, Martin, Cathie, additional, De Canha, Marco Nuno, additional, Lall, Namrita, additional, Qin, Haining, additional, Walker, Barnaby E., additional, Vásquez‐Londoño, Carlos, additional, Allkin, Bob, additional, Rivers, Malin, additional, Simmonds, Monique S. J., additional, Bell, Elizabeth, additional, Battison, Alex, additional, Felix, Juri, additional, Forest, Felix, additional, Leon, Christine, additional, Williams, China, additional, and Nic Lughadha, Eimear, additional

Published
2020
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14. Neoclerodanes from Teucrium orientale.

Author

Bruno, Maurizio, primary, Rosselli, Sergio, additional, Maggio, Antonella, additional, Piozzi, Franco, additional, Scaglioni, Leonardo, additional, Arnold, Nelly A., additional, and Simmonds, Monique S. J., additional

Published
2005
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33. Pharmacodynamics of Aloe vera and acemannan in therapeutic applications for skin, digestion, and immunomodulation.

Author

Sadgrove NJ and Simmonds MSJ

Subjects
Digestion, Immunomodulation, Mannans, Mannose Receptor, Vaccine Efficacy, Aloe
Abstract

Scientific studies of Aloe vera have tentatively explained therapeutic claims from a mechanistic perspective. Furthermore, in vitro outcomes demonstrate that the breakage of acemannan chains into smaller fragments enhances biological effects. These fragments can intravenously boost vaccine efficacy or entrain the immune system to attack cancer cells by mannose receptor agonism of macrophage or dendritic cells. With oral consumption, epithelialisation also occurs at injured sites in the small intestine or colon. The main advantage of dietary acemannan is the attenuation of the digestive process, increasing satiety, and slowing the release of sugars from starches. In the colon, acemannan is digested by microbes into short-chain fatty acids that are absorbed and augment the sensation of satiety and confer a host of other health benefits. In topical applications, an acemannan/chitosan combination accelerates the closure of wounds by promoting granular tissue formation, which creates a barrier between macrophages or neutrophils and the wound dressing. This causes M2 polarisation, reversal of inflammation, and acceleration of the re-epithelialisation process. This review summarises and explains the current pharmacodynamic paradigm in the context of acemannan in topical, oral, and intravenous applications. However, due to contradictory results in the literature, further research is required to provide scientific evidence to confirm or nullify these claims., (© 2021 John Wiley & Sons Ltd.)

Published
2021
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34. Chemical composition and biological activities of polar extracts and essential oil of rose-scented geranium, Pelargonium graveolens.

Author

Boukhris M, Simmonds MS, Sayadi S, and Bouaziz M

Subjects
Anti-Infective Agents chemistry, Anti-Infective Agents isolation & purification, Antioxidants chemistry, Antioxidants isolation & purification, Chromatography, Liquid, Flavonoids chemistry, Flavonoids isolation & purification, Gas Chromatography-Mass Spectrometry, Microbial Sensitivity Tests, Plant Leaves chemistry, Terpenes chemistry, Terpenes isolation & purification, Oils, Volatile chemistry, Pelargonium chemistry, Plant Extracts chemistry
Abstract

Pelargonium graveolens (Geraniaceae) was characterized with respect to its chemical composition, antioxidant potential and antimicrobial activities. This is the first investigation focusing on the comparison of both essential oil and polar extracts from this species. The chemical composition of the essential oil of the aerial parts of P. graveolens was analyzed by gas chromatography/mass spectrometry. The main constituents of the oil were found to be β-citronellol (21.9%), citronellyl formate (13.2%), geraniol (11.1%), 10-epi-γ-eudesmol (7.9%), geranyl formate (6.2%) and (l)-linalool (5.6%). Nine flavonoids were identified by high-performance liquid chromatography-MS in leaf and flower extracts. Kaempferol 3-O-rhamnoside-glucoside, isorhamnetin aglycone, quercetin 3-O-glucoside, kaempferol 3,7-di-O-glucoside, quercetin 3-O-pentose and kaempferol 3-O-glucoside, quercetin 3-O-rhamnoside-glucoside, quercetin 3-O-pentoside-glucoside, myrisetin 3-O-glucoside-rhamnoside flavonoids were detected in methanolic and aqueous extracts, respectively. The total flavonoids ranged between 29.9 and 78.2 mg QE/g in flower water and methanol extracts, respectively, and 22.5 and 71.2 mg QE/g dry weight in leaf water and methanol extracts, respectively. The highest antioxidant activities using two methods of free radical scavenging capacities were obtained with the essential oil (9.16 mM of Trolox and 2.68 µg/ml). All P. graveolens essential oil and polar extracts were active against at least one bacterium., (Copyright © 2012 John Wiley & Sons, Ltd.)

Published
2013
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35. Effects of plant-derived compounds on larvae of a blow fly species that causes secondary myiases: laboratory studies.

Author

Green PW, Simmonds MS, Blaney WM, and Khambay BP

Subjects
Animals, Chrysanthemum cinerariifolium, Diet, Feeding Behavior drug effects, Flowers, Larva drug effects, Limonins pharmacology, Meliaceae, Myiasis prevention & control, Naphthoquinones pharmacology, Plant Extracts pharmacology, Random Allocation, Scrophulariaceae, Diptera drug effects, Insecticides pharmacology, Phytotherapy
Abstract

No-choice and binary-choice bioassays were used to test the effect of a range of plant-derived insecticides on the behaviour of larvae of the black blow fly Phormia regina (Meigen). Azadirachtin (100 and 10 ppm), pyrethrum extract (10 ppm) and the naphthoquinone BTG 505 (1000 ppm) acted as deterrents for P. regina larvae. The mortality of larvae was reduced in instances where they moved away from a treated diet. Larvae given a choice were heavier, when compared with larvae reared exclusively on diets containing either azadirachtin (100 or 10 ppm) or the naphthoquinones, BTG 504 (1000 ppm) or BTG 505 (1000 ppm). The deterrent effect of azadirachtin, pyrethrum and the naphthoquinone BTG 505 together with their larvicidal activity, could be utilized in prophylaxis against myiasis infections due to larvae of Phormia regina.

Published
2004
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