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Your search keyword '"Thomas-Schoemann, A."' showing total 11 results
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11 results on '"Thomas-Schoemann, A."'

1. Cardiac toxicity associated with pharmacokinetic drug–drug interaction between crizotinib and sofosbuvir/velpatasvir: A case report

Author

Monribot, Anthia, primary, Huillard, Olivier, additional, Khoudour, Nihel, additional, Préta, Laure‐Hélène, additional, Blanchet, Benoit, additional, Cabanes, Laure, additional, Batista, Rui, additional, Pallet, Nicolas, additional, Chouchana, Laurent, additional, Goldwasser, François, additional, Sogni, Philippe, additional, and Thomas‐Schoemann, Audrey, additional

Published
2023
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2. Determinants of the interindividual variability in serum cytidine deaminase activity of patients with solid tumours

Author

Jérôme Alexandre, François Goldwasser, Emmanuel Curis, Romain Cohen, Audrey Thomas-Schoemann, Anne Jouinot, V. Joste, Michel Vidal, Olivier Huillard, Céline Narjoz, M. Tiako Meyo, Anatole Cessot, Laure-Hélène Preta, Benoit Blanchet, D. Desaulle, Ioannis Nicolis, Audrey Bellesoeur, and J. Quilichini

Subjects
Male, Antimetabolites, Antineoplastic, medicine.medical_specialty, Cytidine deaminase activity, Pharmacogenomic Variants, Neutrophils, therapeutic drug monitoring, Nutritional Status, Single-nucleotide polymorphism, Deoxycytidine, Polymorphism, Single Nucleotide, 030226 pharmacology & pharmacy, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Cytidine Deaminase, Commentaries, Internal medicine, Biomarkers, Tumor, medicine, Humans, Pharmacology (medical), Prospective Studies, 030212 general & internal medicine, Aged, Inflammation, Pharmacology, Univariate analysis, business.industry, Malnutrition, gemcitabine, Cancer, Cytidine deaminase, Middle Aged, medicine.disease, Gemcitabine, Pancreatic Neoplasms, Biological Variation, Population, Commentary, Absolute neutrophil count, Female, Drug Monitoring, business, Pharmacogenetics, medicine.drug
Abstract

AIMS Cytidine deaminase (CDA) activity in cancer patients' serum has been proposed as a predictive biomarker for efficacy and toxicity of nucleoside analogues. However, discrepant results about its predictive value have been reported due to the high interindividual variability in CDA activity. This study aimed at identifying determinants of this interindividual variability. METHODS From December 2014 to November 2015, 183 patients were prospectively included. Serum CDA activity, biological and clinical characteristics as well as five common single nucleotide polymorphisms (SNPs) in the CDA gene (c.-451C > T, c.-92A > G, c.-33_-31delC, c.79A > C, c.435 T > C) were analysed. Associations between clinical characteristics, pharmacogenetic variants and CDA activity were univariately tested. P

Published
2019

3. Determinants of the interindividual variability in serum cytidine deaminase activity of patients with solid tumours

Author

Cohen, R., primary, Preta, L. H., additional, Joste, V., additional, Curis, E., additional, Huillard, O., additional, Jouinot, A., additional, Narjoz, C., additional, Thomas‐Schoemann, A., additional, Bellesoeur, A., additional, Tiako Meyo, M., additional, Quilichini, J., additional, Desaulle, D., additional, Nicolis, I., additional, Cessot, A., additional, Vidal, M., additional, Goldwasser, F., additional, Alexandre, J., additional, and Blanchet, B., additional

Published
2019
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4. Drug monitoring of sunitinib in patients with advanced solid tumors: a monocentric observational French study

Author

Cabel, Luc, primary, Blanchet, Benoit, additional, Thomas-Schoemann, Audrey, additional, Huillard, Olivier, additional, Bellesoeur, Audrey, additional, Cessot, Anatole, additional, Giroux, Julie, additional, Boudou-Rouquette, Pascaline, additional, Coriat, Romain, additional, Vidal, Michel, additional, Saidu, Nathaniel E. B., additional, Golmard, Lisa, additional, Alexandre, Jérome, additional, and Goldwasser, Francois, additional

Published
2017
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5. Soluble VEGFR-1: A new biomarker of sorafenib-related hypertension

Author

J.P. Durand, Michel Vidal, François Goldwasser, Benoit Blanchet, Jean Louis Golmard, Gaëlle Noé, C. Pages, Audrey Thomas-Schoemann, Céleste Lebbé, Jérôme Alexandre, C. Chenevier-Gobeaux, Jean Guibourdenche, and P. Boudou-Rouquette

Subjects
Pharmacology, Sorafenib, biology, business.industry, VEGF receptors, Cancer research, biology.protein, Biomarker (medicine), Medicine, Pharmacology (medical), business, medicine.drug
Published
2014

6. Soluble VEGFR-1: A new biomarker of sorafenib-related hypertension

Author

Thomas-Schoemann, A., primary, Blanchet, B., additional, Boudou-Rouquette, P., additional, Golmard, J.L., additional, Noé, G., additional, Chenevier-Gobeaux, C., additional, Lebbe, C., additional, Pages, C., additional, Durand, J.P., additional, Alexandre, J., additional, Goldwasser, F., additional, Guibourdenche, J., additional, and Vidal, M., additional

Published
2014
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9. Bystander effect of vinorelbine alters antitumor immune response

Author

Thomas-Schoemann, Audrey, primary, Lemare, François, additional, Mongaret, Céline, additional, Bermudez, Elisabeth, additional, Chéreau, Christiane, additional, Nicco, Carole, additional, Dauphin, Alain, additional, Weill, Bernard, additional, Goldwasser, François, additional, Batteux, Frédéric, additional, and Alexandre, Jérôme, additional

Published
2011
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11. Soluble VEGFR-1: a new biomarker of sorafenib-related hypertension (i.e., sorafenib-related is the compound adjective?).

Author

Thomas-Schoemann A, Blanchet B, Boudou-Rouquette P, Golmard JL, Noé G, Chenevier-Gobeaux C, Lebbe C, Pages C, Durand JP, Alexandre J, Goldwasser F, Guibourdenche J, and Vidal M

Subjects
Female, Humans, Male, Angiogenesis Inhibitors pharmacology, Angiopoietin-2 blood, Niacinamide analogs & derivatives, Phenylurea Compounds pharmacology, Vascular Endothelial Growth Factor A blood, Vascular Endothelial Growth Factor Receptor-2 blood
Published
2015
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