1. Layered Plaque in Organic Lesions in Patients With Coronary Artery Spasm
- Author
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Takeshi Nishi, Teruyoshi Kume, Ryotaro Yamada, Hiroshi Okamoto, Satsohi Koto, Masahiro Yamashita, Masahiko Ueno, Kyo Kamisaka, Yoshitaka Sasahira, Ayano Enzan, Yasuyuki Sudo, Tomoko Tamada, Terumasa Koyama, Koichiro Imai, Yoji Neishi, and Shiro Uemura
- Subjects
coronary artery spasm ,healed plaque ,layered plaque ,optical coherence tomography ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background Coronary artery spasm plays a vital role in the pathogenesis of coronary plaques. We sought to investigate the plaque characteristics of co‐existing organic lesions in patients with coronary artery spasm in comparison to those without coronary artery spasm by intracoronary optical coherence tomography (OCT). Methods and Results We included 39 patients who presented with a symptom suspected of coronary spastic angina and had an organic lesion, defined as ≥plaque burden of 50% assessed by OCT. Coronary artery spasm was diagnosed by positive acetylcholine provocation test, or by spontaneous spasm detected during coronary angiography. A total of 51 vessels with an organic lesion were identified. Of these, coronary artery spasm was observed in 30 vessels (spasm), while not in 21 vessels (non‐spasm). Organic lesions in the spasm vessels, compared with those in the non‐spasm vessels, had a higher prevalence of layered plaque (93% versus 38%, P
- Published
- 2022
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