1. Rapid maxillary expansion for pediatric obstructive sleep apnea: A systematic review and meta-analysis
- Author
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Edward T. Chang, Jose Abdullatif, Victor Certal, Soroush Zaghi, Paola Pirelli, Sungjin A. Song, Macario Camacho, and Christian Guilleminault
- Subjects
Pediatrics ,medicine.medical_specialty ,business.industry ,Sleep apnea ,030206 dentistry ,medicine.disease ,Sleep medicine ,respiratory tract diseases ,law.invention ,Obstructive sleep apnea ,03 medical and health sciences ,0302 clinical medicine ,Otorhinolaryngology ,Randomized controlled trial ,law ,Meta-analysis ,Anesthesia ,medicine ,Rapid maxillary expansion ,Sleep study ,business ,030217 neurology & neurosurgery ,Oxygen saturation (medicine) - Abstract
Objectives/Hypothesis To perform a systematic review with meta-analysis for sleep study outcomes in children who have undergone rapid maxillary expansion (RME) as treatment for obstructive sleep apnea (OSA). Data Sources PubMed/MEDLINE and eight additional databases. Review Methods Three authors independently and systematically reviewed the international literature through February 21, 2016. Results Seventeen studies reported outcomes for 314 children (7.6 ± 2.0 years old) with high-arched and/or narrow hard palates (transverse maxillary deficiency) and OSA. Data were analyzed based on follow-up duration: ≤3 years (314 patients) and >3 years (52 patients). For ≤3-year follow-up, the pre- and post-RME apnea–hypopnea index (AHI) decreased from a mean ± standard deviation (M ± SD) of 8.9 ± 7.0/hr to 2.7 ± 3.3/hr (70% reduction). The cure rate (AHI 3-year follow-up (range = 6.5–12 years), the AHI was reduced from an M ± SD of 7.1 ± 5.7/hr to 1.5 ± 1.8/hr (79% reduction). Conclusions Improvement in AHI and lowest oxygen saturation has consistently been seen in children undergoing RME, especially in the short term (
- Published
- 2016