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21 results on '"WANG Baohui"'

20. Computational model-based hemodynamic comparisons of traditional and modified idealized models of autologous radiocephalic fistula.

Author

Wang F, Wang B, Guo J, Zhang T, Mu W, and Liu C

Subjects
Humans, Renal Dialysis, Blood Flow Velocity physiology, Arteriovenous Shunt, Surgical methods, Arteriovenous Fistula physiopathology, Arteriovenous Fistula surgery, Hydrodynamics, Radial Artery physiopathology, Radial Artery physiology, Radial Artery surgery, Stress, Mechanical, Hemodynamics physiology, Computer Simulation, Models, Cardiovascular
Abstract

Autologous arteriovenous fistula (AVF) is a commonly used vascular access (VA) for hemodialysis, and hemodynamic changes are one of the main factors for its failure. To explore the effect of geometry on the hemodynamics in the AVF, a modified model is built with a gradual and smooth turn at the anastomosis and is compared with the traditional model, which has an abrupt sharp turn at the anastomisis. Transient computational fluid dynamics (CFD) simulations were performed for the comparison and analysis of the hemodynamic fields of the two models at different stages of the pulse cycle. The results showed that the low shear stress region and high oscillatory shear stress region in the modified AVF model coincided with regions of intimal hyperplasia that have been identified by previous studies. A comparison with the blood flow velocities measured in vivo was performed, and the error between the simulation results and the medical data was reduced by 22% in the modified model, which verifies the rationality and utility of the modified model., (© 2024 John Wiley & Sons Ltd.)

Published
2024
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21. Impact of Alendronate Sodium plus Elcatonin on Postoperative Bone Pain in Patients with Osteoporotic Fractures.

Author

Wang B, Sun Y, Shi D, Han X, Liu N, and Wang B

Subjects
Alkaline Phosphatase, Calcitonin analogs & derivatives, Humans, Osteocalcin, Pain, Postoperative drug therapy, Parathyroid Hormone, Alendronate therapeutic use, Osteoporotic Fractures complications, Osteoporotic Fractures drug therapy, Osteoporotic Fractures surgery
Abstract

Objective: This research aims to investigate and analyze the impact of alendronate sodium (ALN) plus elcatonin (EC) in treating postoperative bone pain (BP) in patients with osteoporotic fractures (OPFs)., Methods: One hundred and thirty-eight cases of OPFs admitted between July 2018 and July 2021 were selected, of which 68 cases receiving ALN were set as the control group and 70 cases receiving ALN plus EC were set as the research group. Intercomparisons were performed in terms of BP, curative effect, complication rate, and serum bone metabolism indexes such as bone Gla protein (BGP), parathyroid hormone (PTH), and bone alkaline phosphatase (BALP)., Results: Better postoperative BP relief, higher overall response rate, and lower complication rate were identified in the research group versus the control group. On the other hand, the research group presented with increased BGP and BALP after treatment, higher than those in the control group, while the posttreament PTH decreased obviously and was lower versus the control group., Conclusions: For OPF patients, ALN plus EC contributes to significantly reduced postoperative BP, improved clinical efficacy, higher treatment safety, and better bone metabolism, which has high clinical application value., Competing Interests: The authors declare no competing interests., (Copyright © 2022 Baohui Wang et al.)

Published
2022
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