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Abstract A dual‐mode dielectric resonator antenna based on a microstrip line‐slot coupling feed, operating in both the GMS‐900 and GMS‐1800 frequency bands, is presented. The antenna structure consists of a rectangular dielectric substrate and a cylindrical dielectric resonator, which is fed by a microstrip line‐slot coupling. The cylindrical resonant cavity and the dual‐stub coupling slot are designed so that the HEM111 and HEM311 modes are excited simultaneously, resulting in resonance at the two desired frequency points. The gain of the antenna is 3.74 and 7.63 dBi at 0.9 and 1.8 GHz respectively, and the efficiency of the antenna is greater than 70% in both operating bands.

Abstract Background Hypospadias is a common congenital malformation of male external genitalia, which mainly manifests as an abnormal urethral opening on the ventral side of the penis. The etiology and clinical phenotype of hypospadias is highly heterogeneous, and its clinical diagnosis is challenging. Currently, over 70% of patients have an unknown etiology. Here, we performed a targeted analysis of gene mutations in 130 patients with hypospadias of unknown etiology to find the precise genetic cause. Methods We developed a targeted next‐generation sequencing (NGS) panel, encompassing the exon coding regions of 105 genes involved in external genitalia and urogenital tract development and performed sequencing analysis on 130 children with hypospadias of unknown etiology. Results In total, 25 patients with hypospadias (19.2%) were found to have 20 mutations among the nine genes involved in external genitalia and urogenital tract development, including 16 reported and four novel mutation sites. Twenty‐two patients (16.9%) had diagnostic variants. Multiple genetic mutations were identified in three of the 25 patients. Hypospadias combined with micropenis was the most common phenotype (68%) in 25 patients. Conclusions Higher frequency mutations were identified in SRD5A2 (52%) and AR (24%) in our patient cohort. Middle or posterior hypospadias with micropenis may be significant indicators of genetic variations. Polygenic inheritance may be a rare genetic cause of hypospadias.