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6-Aminoquinolines are available as potential intermediates in drug design using p-chloroaniline as an optimal oxidant in the Skraup—Doebner—von Miller reaction.

A task-specific ionic liquid, 1,8-diazabicyclo[5.4.0]-undec-7-en-8-ium acetate has been successfully used as a catalyst for aza-conjugate addition of aliphatic or aromatic amines to various electron deficient alkenes under solvent-free conditions and at room temperature. The catalyst can be reused for six times without noticeable loss of activity.