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Your search keyword '"Yao, Zhicheng"' showing total 17 results
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17 results on '"Yao, Zhicheng"'

1. Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple‐Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy

Author

Lei, Josh Haipeng, primary, Lee, Mi‐Hye, additional, Miao, Kai, additional, Huang, Zebin, additional, Yao, Zhicheng, additional, Zhang, Aiping, additional, Xu, Jun, additional, Zhao, Ming, additional, Huang, Zenan, additional, Zhang, Xin, additional, Chen, Si, additional, Jiaying, NG, additional, Feng, Yuzhao, additional, Xing, Fuqiang, additional, Chen, Ping, additional, Sun, Heng, additional, Chen, Qiang, additional, Xiang, Tingxiu, additional, Chen, Lin, additional, Xu, Xiaoling, additional, and Deng, Chu‐Xia, additional

Published
2023
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2. Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple‐Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy

Author

Lei, Josh Haipeng, primary, Lee, Mi‐Hye, additional, Miao, Kai, additional, Huang, Zebin, additional, Yao, Zhicheng, additional, Zhang, Aiping, additional, Xu, Jun, additional, Zhao, Ming, additional, Huang, Zenan, additional, Zhang, Xin, additional, Chen, Si, additional, Jiaying, NG, additional, Feng, Yuzhao, additional, Xing, Fuqiang, additional, Chen, Ping, additional, Sun, Heng, additional, Chen, Qiang, additional, Xiang, Tingxiu, additional, Chen, Lin, additional, Xu, Xiaoling, additional, and Deng, Chu‐Xia, additional

Published
2021
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3. Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis

Author

Ding, Hongrong, primary, Chen, Shujie, additional, Pan, Xiaohan, additional, Dai, Xiaoshuang, additional, Pan, Guihua, additional, Li, Ze, additional, Mai, Xudong, additional, Tian, Ye, additional, Zhang, Susu, additional, Liu, Bingdong, additional, Cao, Guangchao, additional, Yao, Zhicheng, additional, Yao, Xiangping, additional, Gao, Liang, additional, Yang, Li, additional, Chen, Xiaoyan, additional, Sun, Jia, additional, Chen, Hong, additional, Han, Mulan, additional, Yin, Yulong, additional, Xu, Guohuan, additional, Li, Huijun, additional, Wu, Weidong, additional, Chen, Zheng, additional, Lin, Jingchao, additional, Xiang, Liping, additional, Hu, Jun, additional, Lu, Yan, additional, Zhu, Xiao, additional, and Xie, Liwei, additional

Published
2021
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4. Clinical prognostic evaluation of immunocytes in different molecular subtypes of breast cancer

Author

Huang Ze-nan, Yang Xiongbin, Li Zixiong, Liu Ren-bin, Wang Tiantian, Yao Zhicheng, Huang Mei, Jia Changchang, and Dong Min

Subjects
Blood Platelets, 0301 basic medicine, Oncology, Aging, medicine.medical_specialty, Multivariate analysis, Receptor, ErbB-2, Physiology, Lymphocyte, Clinical Biochemistry, Breast Neoplasms, Triple Negative Breast Neoplasms, Basophil, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Internal medicine, White blood cell, Biomarkers, Tumor, Leukocytes, medicine, Humans, Retrospective Studies, business.industry, Cell Biology, Middle Aged, Eosinophil, Prognosis, medicine.disease, Immunohistochemistry, Peripheral blood, Gene Expression Regulation, Neoplastic, Logistic Models, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cohort, Female, business
Abstract

To retrospectively analyze the relationship between preoperative blood parameters and postoperative clinical outcomes in patients with different molecular subtypes of breast cancer (BC), a cohort of 601 patients with BC in the Third Affiliated Hospital, Sun Yat-sen University, was retrospectively reviewed. They were categorized into four subtypes according to the expression of ER, PR, HER-2, and KI-67%. White blood cell, neutrophil, lymphocyte, monocyte, eosinophil, basophil, and platelet counts, the neutrophil-to-lymphocyte ratio (NLR), the neutrophil-to-monocyte ratio (NMR), the lymphocyte-to-monocyte ratio (LMR), and the platelet-to-lymphocyte ratio (PLR) were recorded. Univariate and multivariate analyses were performed to identify the relationship between parameters and ratios and disease-free survival (DFS) and overall survival (OS). Luminal subtypes of BC had smaller tumor volume, better differentiation degree of invasive ductal carcinoma, less lymph node metastasis, and better clinical outcome than the HER-2 overexpression and triple-negative BC (TNBC) subtypes. In multivariate analysis, age and LMR were the independent prognostic factors of DFS in patients with luminal A (age, p = 0.005; LMR, P = 0.026); PLR in patients with luminal B (DFS; p = 0.032; OS, p= 0.012); LMR in patients with HER-2 overexpression (DFS; p = 0.008; OS, p = 0.017); and NLR for DFS (p = 0.014); and WBC for OS (p = 0.008) in patients with TNBC. LMR was the benign predictor of luminal A and HER-2 overexpression. PLR was the adverse predictor of luminal B. WBC and NLR were the adverse predictors of TNBC. Therefore, these peripheral blood parameters can play an important role in the diagnosis and treatment of patients with different molecular subtypes of BC.

Published
2019

9. ZKSCAN1gene and its related circular RNA (circZKSCAN1) both inhibit hepatocellular carcinoma cell growth, migration, and invasion but through different signaling pathways

Author

Zejian Huang, Jingyan Luo, Yao Zhicheng, Kunpeng Hu, Peng Zhang, Qiangliang Wang, Yang Yang, Zhiyong Xiong, Chonghua He, Jizong Lin, He Huang, and Bo Liu

Subjects
Male, 0301 basic medicine, Cancer Research, 0302 clinical medicine, Cell Movement, HCC, Research Articles, Liver Neoplasms, qRT‐PCR, General Medicine, Middle Aged, Gene Expression Regulation, Neoplastic, Reverse transcription polymerase chain reaction, Real-time polymerase chain reaction, Oncology, ZKSCAN1, 030220 oncology & carcinogenesis, RNA‐seq, Molecular Medicine, Female, Corrigendum, Research Article, Signal Transduction, Carcinoma, Hepatocellular, Down-Regulation, Mice, Nude, Biology, 03 medical and health sciences, Downregulation and upregulation, Circular RNA, Cell Line, Tumor, Genetics, Animals, Humans, Gene silencing, Neoplasm Invasiveness, RNA, Messenger, Transcription factor, Cell Proliferation, Demography, Base Sequence, Sequence Analysis, RNA, Cell growth, Gene Expression Profiling, Reproducibility of Results, RNA, circular RNA, RNA, Circular, Molecular biology, 030104 developmental biology, ROC Curve, Transcription Factors
Abstract

There is increasing evidence that circular RNA (circRNA) are involved in cancer development, but the regulation and function of human circRNA remain largely unknown. In this study, we demonstrated that ZKSCAN1, a zinc finger family gene, is expressed in both linear and circular (circZKSCAN1) forms of RNA in human hepatocellular carcinoma (HCC) tissues and cell lines. Here, we analyzed a cohort of 102 patients and found that expression of both ZKSCAN1 mRNA and circZKSCAN1 was significantly lower (P

Published
2017

12. ZKSCAN1gene and its related circular RNA (circZKSCAN1) both inhibit hepatocellular carcinoma cell growth, migration, and invasion but through different signaling pathways

Author

Yao, Zhicheng, primary, Luo, Jingyan, additional, Hu, Kunpeng, additional, Lin, Jizong, additional, Huang, He, additional, Wang, Qiangliang, additional, Zhang, Peng, additional, Xiong, Zhiyong, additional, He, Chonghua, additional, Huang, Zejian, additional, Liu, Bo, additional, and Yang, Yang, additional

Published
2017
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