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Abstract As a clinical subtype of SWI/SNF‐related intellectual disability syndromes, Nicolaides–Baraitser syndrome (NCBRS, OMIM601358) has a unique genotype–phenotype. Due to the scarcity of the number of cases reported and the limitations of diagnosis methods, so far only more than 80 cases have been reported worldwide. In this article, a new patient with a de novo mutation was followed up for 10 years; it includes the epilepsy treatment process, the characteristics of NBCRS with seizures, typical faces, sparse hair, prominent interphalangeal joints, and intellectual disability, and we also summarized the genotype–phenotype of the 80 reported cases for comparison. Due to insufficient studies and lack of attention paid to the syndrome, it is believed that the actual number of cases should be far more than the reported number. The syndrome is phased and progressive. The genotype–phenotype correlation of the disease is related to the location of the gene locus, especially closely related to the SNF2 ATPase domain. Conclusions The understanding of NCBRS is lagging, we need to strengthen the screening process of the phenotypic disease with intellectual disability, and perfecting multiple types of diagnostic techniques will help the discovery of the disease; its clinical features are staged and are slowly progressive, and long‐term prognosis must be taken precautious with long‐term follow‐up required.

Block Yingmai 7 is structurally located in the western segment of the southern margin of the Kuqa Depression in the Tarim Basin. In the foreland basin, huge continental Mesozoic and Cenozoic strata have been deposited. In recent years, the Paleogene bottom sandstone section has been the main oil and gas exploration horizon. In order to further improve the oil and gas exploration effect of the Paleogene bottom sandstone in the study area and improve the accuracy of reservoir prediction, based on the related theory of sedimentology and petrology, this paper analyzes and studies the cores obtained by drilling in the Paleogene through laboratory core analysis experiments. The study shows that the Paleogene bottom sandstone is a braided river delta sedimentary system, and the sedimentary microfacies are mainly underwater distributary channels. The sandstone type is mainly light gray lithic feldspar fine sandstone, the sandstone debris particle sorting degree is medium-good, and the roundness is sub-edge-sub-circular. The microscopic characteristics of the reservoir are large pore throat radius, low displacement pressure, mainly intergranular pores, and good pore connectivity. It is a thin-layered mesoporous, medium-permeable, large-throat, and strongly heterogeneous reservoir. Finally, a classification evaluation table of reservoirs in block Yingmai 7 is established, and it is considered that the reservoirs of types I and II are enriched areas of oil and gas resources. The research results provide evidence for the prediction of oil and gas reservoirs.