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Your search keyword '"Zhou, Zhihao"' showing total 23 results
Start Over Author "Zhou, Zhihao" Publisher wiley
23 results on '"Zhou, Zhihao"'

5. Cell Development Enhanced Bionic Silk Hydrogel on Remodeling Immune Pathogenesis of Spinal Cord Injury via M2 Polarization of Microglial

Author

Ling, Jue, primary, Huang, Tingting, additional, Wu, Ronghua, additional, Ma, Chao, additional, Lin, Ge, additional, Zhou, Zhihao, additional, Wang, Junpei, additional, Tu, Qifeng, additional, Tang, Xiaoxuan, additional, Liu, Yan, additional, Liu, Mei, additional, Yang, Liu, additional, and Yang, Yumin, additional

Published
2023
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6. Aberrant branched‐chain amino acid accumulation along the microbiota–gut–brain axis: Crucial targets affecting the occurrence and treatment of ischaemic stroke

Author

Shen, Jiajia, primary, Guo, Huimin, additional, Liu, Shijia, additional, Jin, Wei, additional, Zhang, Zhi‐Wei, additional, Zhang, Yong, additional, Liu, Keanqi, additional, Mao, Shuying, additional, Zhou, Zhihao, additional, Xie, Lin, additional, Wang, Guangji, additional, Hao, Haiping, additional, and Liang, Yan, additional

Published
2022
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12. A Personalized Acoustic Interface for Wearable Human–Machine Interaction

Author

Lin, Zhiwei, primary, Zhang, Gaoqiang, additional, Xiao, Xiao, additional, Au, Christian, additional, Zhou, Yihao, additional, Sun, Chenchen, additional, Zhou, Zhihao, additional, Yan, Rong, additional, Fan, Endong, additional, Si, Shaobo, additional, Weng, Lei, additional, Mathur, Shaurya, additional, Yang, Jin, additional, and Chen, Jun, additional

Published
2021
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20. Flexible Weaving Constructed Self‐Powered Pressure Sensor Enabling Continuous Diagnosis of Cardiovascular Disease and Measurement of Cuffless Blood Pressure

Author

Meng, Keyu, primary, Chen, Jun, additional, Li, Xiaoshi, additional, Wu, Yufen, additional, Fan, Wenjing, additional, Zhou, Zhihao, additional, He, Qiang, additional, Wang, Xue, additional, Fan, Xing, additional, Zhang, Yuxin, additional, Yang, Jin, additional, and Wang, Zhong Lin, additional

Published
2018
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22. Aberrant branched-chain amino acid accumulation along the microbiota-gut-brain axis: Crucial targets affecting the occurrence and treatment of ischaemic stroke.

Author

Shen J, Guo H, Liu S, Jin W, Zhang ZW, Zhang Y, Liu K, Mao S, Zhou Z, Xie L, Wang G, Hao H, and Liang Y

Subjects
Rats, Animals, Brain-Gut Axis, Amino Acids, Branched-Chain metabolism, Stroke drug therapy, Stroke metabolism, Brain Ischemia drug therapy, Brain Ischemia metabolism, Ischemic Stroke drug therapy
Abstract

Background and Purpose: Although increasing evidence illustrated that the bidirectional communication between the brain and the gut is closely related to the occurrence of various complex diseases. Limited effort has been made to explore the influence of intestinal flora on the risk of ischaemic stroke. The present study aims to identify microbiota and specialized microbiota metabolites related to the occurrence and treatment of ischaemic stroke., Experimental Approach: The role of microbiota in the occurrence and the treatment of ischaemic stroke was evaluated on ischaemia/reperfusion (I/R), pseudo-germ-free and faecal transplantation animals. The target microbiota and specialized metabolites were identified by comparing their distribution in flora and metabolomic profiles in ischaemic stroke patients and animals with compared with healthy controls. The effects and mechanisms involved of the targeted metabolites in ischaemic stroke were explored in ischaemia/reperfusion rats, hypoxia/reoxygenation PC12 cells and LPS-induced inflammatory BV2 cells., Key Results: Both ischaemic stroke patients and I/R rats had significant accumulation of branched-chain amino acids, which were closely associated with gut microflora dysbiosis and the development of ischaemic stroke. Lactobacillus helveticus (L.hel) and Lactobacillus brevis (L.bre) are identified as the microbiota most affected by ischaemia/reperfusion modelling and treatment. L.hel and L.bre colonization exhibited significant neuroprotective activity and could greatly alleviate the accumulation of branched-chain amino acids. In addition, branched-chain amino acid (BCAA) accumulation was shown to exacerbate microglia-induced neuroinflammation by activating AKT/STAT3/NF-κB signalling., Conclusion and Implications: Our findings demonstrated the crucial role of intestinal flora and microbiota metabolites in the occurrence and treatment of ischaemic stroke., (© 2022 British Pharmacological Society.)

Published
2023
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23. Feasibility and accuracy of orthopaedic surgical robot system for intraoperative navigation to locate bone tunnel in anterior cruciate ligament reconstruction.

Author

Ding G, Yang G, Zhang J, Huang H, Du J, Ren S, Wang Q, Zhou Z, Zhang X, and Ao Y

Subjects
Anterior Cruciate Ligament surgery, Feasibility Studies, Femur surgery, Humans, Tibia surgery, Anterior Cruciate Ligament Reconstruction methods, Orthopedics, Robotics
Abstract

Background: The combination of navigational system and robotics has the potential to accurately identify and drill bone tunnels in anterior cruciate ligament (ACL) reconstruction. This study explores the feasibility and accuracy of bone tunnel positioning using the TiRobot, an orthopaedic surgical robot., Methods: The experiment was divided into two groups. In group A, the bone tunnels were positioned using the TiRobot surgical robot (n = 8). In group B, handheld locators were used for positioning (n = 8)., Results: TiRobot can be used for positioning the ACL bone tunnel. The accuracy of positioning the femoral tunnel in group A and B was 1.00 ± 0.20 and 3.10 ± 0.59 mm, respectively (t = -9.49, P < 0.001). As for tibial tunnel, the accuracy was 1.02 ± 0.20 and 2.64 ± 0.14 mm, respectively (t = -18.54, P < 0.001)., Conclusions: The bone tunnel drilling precision using TiRobot for ACL reconstruction surgery was more accurate than traditional surgical techniques., (© 2021 John Wiley & Sons Ltd.)

Published
2022
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