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Quantifying and separating different sources of uncertainty helps to improve the understanding of the projected effects of climate change and can inform decision‐making in adaptation planning. This paper (1) evaluated four process‐based crop models; (2) assessed the effects of climate change on maize yield using climate change outputs from seven global climate models (GCMs) under three representative concentration pathways (RCPs); and (3) disaggregated the contributions of multiple crop models, GCMs and RCPs to overall uncertainty. All four models captured more than 80% of the variation in days to silking, maturity and yield, indicating reasonably reproduced observations. Similarly, the root mean square errors were moderate for days to silking and maturity (fewer than 4 days) and yield (0.5–0.7 t/ha). Overall, the results indicate that the models could assess grain yield at the study sites reasonably well. The results of the multiple models ensemble indicate that the maize yield will decrease by 9–11% with a probability of 72–80% on average during the period 2010–2039 relative to the baseline (1976–2005). The uncertainty in the maize‐yield simulations might arise mostly from the GCM models, followed by the crop models and RCPs, the contribution of which could be neglected relative to the other factors. Therefore, the use of a multiple crop model and a GCM ensemble is advisable in order to account properly for uncertainties in crop assessments. The uncertainty in maize‐yield simulations might arise mostly from global climate models (GCMs), followed by crop models and representative concentration pathways (RCPs), the contribution of which could be neglected relative to the other factors. Therefore, the use of a multiple crop model and a GCM ensemble is advisable in order to account properly for uncertainties in crop assessments. [ABSTRACT FROM AUTHOR]