Search

Your search keyword '"Sun, Xiaoning"' showing total 1 results
Start Over Author "Sun, Xiaoning" Topic chlorination Publisher wiley-blackwell

Refine your results

1 results on '"Sun, Xiaoning"'

1. Regioselective Chlorination of Quinoline N-Oxides and Isoquinoline N-Oxides Using PPh3/Cl3CCN.

Author

Qiao, Kai, Wan, Li, Sun, Xiaoning, Zhang, Kai, Zhu, Ning, Li, Xin, and Guo, Kai

Subjects
*QUINOLINE, *CHLORINATION, *REGIOSELECTIVITY (Chemistry), *ISOQUINOLINE, *NITROGEN oxides, *FUNCTIONAL groups
Abstract

A novel method for the regioselective C2-chlorination of heterocyclic N-oxides has been developed. PPh3/Cl3CCN were used as chlorinating reagents and the desired N-heterocyclic chlorides were obtained smoothly in satisfactory yields. The reactions proceeded in a highly efficient and selective manner across a broad range of substrates demonstrating excellent functional group tolerance. In addition, this chlorination reaction can be used for the modification of N-heterocyclic scaffolds of appealing ligands and pharmaceuticals. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results