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Your search keyword '"Li Shen"' showing total 4 results
Start Over Author "Li Shen" Topic organocatalysis Publisher wiley-blackwell
4 results on '"Li Shen"'

1. Enantioselective Addition of Enamides to Cyclic Ketimines: Access to Chiral 3,3‐Disubstituted Isoindolin‐1‐Ones.

Author

Feng, Fang‐Fang, Li, Jin‐Shan, Li, Shen, and Ma, Jun‐An

Subjects
IMINES, ORGANOCATALYSIS, CATALYSIS
Abstract

An enantioselective addition of enamides to cyclic ketimines generated in situ from 3‐hydroxyisoindolin‐1‐ones was developed. This reaction takes advantage of readily available substrates, mild reaction conditions, as well as enlarged reaction generality, affording chiral 3,3‐disubstituted isoindolin‐1‐ones with a quaternary stereogenic center in high yields (up to 98%) and enantioselectivities (up to 99% ee). [ABSTRACT FROM AUTHOR]

Published
2019
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2. ChemInform Abstract: Highly Enantioselective Decarboxylative Mannich Reaction of Malonic Acid Half Oxyesters with Cyclic Trifluoromethyl Ketimines: Synthesis of β-Amino Esters and anti-HIV Drug DPC 083.

Author

Yuan, Hai‐Na, Li, Shen, Nie, Jing, Zheng, Yan, and Ma, Jun‐An

Subjects
*CARBOXYLATES, *MANNICH reaction, *MALONIC acid, *TRIFLUOROMETHYL compounds, *IMINES, *CHEMICAL synthesis, *ENANTIOMERS
Abstract

DPC 083 (X) is prepared in 5 steps starting from the enantiomer of Va. [ABSTRACT FROM AUTHOR]

Published
2014
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4. ChemInform Abstract: Asymmetric Enynylation of N-Sulfonyl Aldimines Catalyzed by Zn-BINOL Complexes.

Author

Yang, Zhen‐Yan, Liu, Tian‐Lin, Zheng, Yan, Li, Shen, and Ma, Jun‐An

Subjects
*ENANTIOSELECTIVE catalysis, *ALDIMINES, *BINAPHTHOL
Abstract

Various enyne carbinamine products are highly enantioselectively obtained by catalytic asymmetric addition of terminal 3-en-1-ynes to N-sulfonyl aldimines in the presence of Zn-BINOL complexes which are generated in situ from ZnMe2 and chiral binol-type ligands. [ABSTRACT FROM AUTHOR]

Published
2015
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