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Proton exchange membrane water electrolysis (PEMWE) is a promising technology for green hydrogen production, although its widespread development with state‐of‐the‐art loadings is threatened by the scarcity of iridium (Ir). Homogeneous dispersion of Ir in an immiscible electro‐ceramic matrix can enhance catalytic mass activity and structural stability. The study presents IrySn0.9(1−y)Sb0.1(1−y)Ox solid solutions produced by highly scalable flame spray pyrolysis (FSP) process as efficient anode electrocatalysts for PEMWE, containing only 0.2 mg cm−2 of Ir in the catalyst layer (CL). Intense mixing of metal vapor and large thermal gradients in the precursor‐derived high‐temperature flame aids stabilizing sub‐nanoscale entropic mixing within self‐preserved 4–6 nm particles. Detailed investigations confirm that the one‐step prepared solid solution electrocatalysts exhibit up to fourfold higher activity toward the oxygen evolution reaction (OER) compared to Ir black. The anode of a PEMWE utilizing this catalyst exhibits high performance and stability over 2000 h but with tenfold lower Ir loading than the state‐of‐art. [ABSTRACT FROM AUTHOR]

Summary: A new circular cavity‐backed slot antenna, which produces unidirectional radiation patterns, has been developed for wireless communication systems. The antenna utilizes substrate‐integrated waveguide (SIW) technology to create a low‐profile cavity. The metal cladding on top of the cavity has an engraved circular ring slot for radiation, and a microstrip transition feeding mechanism is used to excite the perturbed circular slot antenna element located away from the centre of the cavity. Two rectangular cuts, including slots and a shorted via probe, improve radiation performance and bandwidth matching by nearly −40 dB over the working frequency range. An optimized spacing of 0.6 mm is established between the patch centre and the input microstrip transition feed, which produces a circularly polarized (CP) wave. The antenna uses CP SIW technology to operate within a wide impedance bandwidth of 12.18% (10.02–11.31 GHz) below −10 dB and an ARBW of 320 MHz (10.40–10.72 GHz). Both experimental and simulated results agree on s‐parameters, and the antenna's gain, axial ratio, and radiation patterns are consistent. With 7.45 dB CP gain and planar integration, the antenna radiates unidirectional, making it suitable for lightweight wireless broadband applications. [ABSTRACT FROM AUTHOR]

Highlights Carbon fiber reinforced thermoplastics (CFRTP) are gaining momentum, largely due to the benefits of in situ curing, which eliminates long cure times. This makes them an ideal choice for rapid manufacturing using automated tape‐layup machines. Given the sensitivity of thermoplastic properties to processing parameters, a detailed experimental characterization of interlaminar consolidation capacity is crucial before adoption. In this study, we placed poly‐ether‐ketone‐ketone (PEKK) thermoplastic tapes using a robotic tape‐layup machine and consolidated them via compression molding. The resulting samples were experimentally characterized to obtain the thermo‐mechanical performance as a function of consolidation pressure, duration, and ply‐stack orientation for a total of 15 testing cases. Our findings show that the modulus and strength of the laminates with similar ply‐stack orientation can change significantly by up to 200%, based on different processing parameters. The time for interlaminar chain diffusion emerged as the most influential processing parameter. This work provides a benchmark for properties to be targeted with automated fiber placement techniques and underscores the importance of detailed experimental characterization in adopting such techniques. Processing parameters can affect the tensile strength of CF/PEKK by up to 200%. Consolidation time is the most influential processing parameter for CF/PEKK. Crystallinity only affects ultimate tensile properties and not stiffness. In‐plane shear is primarily controlled by interlaminar chain diffusion. Outgassing in the interfibrous region can cause significant voids. [ABSTRACT FROM AUTHOR]

Adhesively bonded joints play a vital role in improving the structural performance of 3D‐printed components. This research aims to examine the effect of graphene inclusion on the failure load and vibrational behavior of polylactic acid flat‐joggle‐flat (FJF) joints prepared using fused deposition modeling. The present research focused on the effect of print directions (0°, 45°, 90°) and the inclusion of graphene nanofiller (0.25, 0.50, 0.75, and 1.00 wt%) on the performance of FJF joints. The effect of raster direction on mechanical properties was examined by tensile testing of dog‐bone samples. Results showed that 0° print orientation had higher tensile strength compared to other printing directions. Shear testing of FJF joints indicated that the inclusion of graphene has enhanced the strength of 3D‐printed FJF joints by 61.18%. Fractography results showed that the formation of the shear band with the inclusion of 0.50 wt% graphene helps to distribute the stress more evenly and prevent catastrophic failure of the FJF joint. The free vibrational test revealed that the inclusion of 0.50 wt% graphene had improved the natural frequencies, as the presence of graphene‐enhanced the interfacial bonding between FJF adherend and adhesive. Highlights: 0° print orientation had higher tensile strength than other printing directions.Inclusion of graphene‐enhanced the shear strength of flat‐joggle‐flat (FJF) joints by 61.18%.Shear band formation delayed the failure of graphene‐reinforced FJF joints.FJF reinforced with 0.50 wt% graphene had adherend failure.FJF joint added with 1.0 wt% graphene had lower natural frequencies. [ABSTRACT FROM AUTHOR]

In this work, a plant‐based composite materials that can be used as food packaging has been developed. Juniperus communis L. extract, which is known to have good antibacterial activity, was added to poly(butylene adipate‐co‐terephthalate) (PBAT) at different percentage (1%, 5%, 10%, 15%, 20%) and produced films by solution casting method. All the prepared PBAT films were subjected to characterization techniques like attenuated total reflection‐infrared spectroscopy (ATR‐IR), x‐ray diffraction (XRD), surface morphology, thermal stability, mechanical strength, film color, opacity, wettability, and antibacterial properties. Thermogravimetric analysis (TGA) was conducted on thermal stability of PBAT composite films. To examine the suitability of composite films for food packaging, measurements on opacity and water vapor permeability have been performed. It was determined that the higher the percentage of Juniperus communis L., which enhanced the test results. The PBAT composite films' antibacterial activity against both gram‐positive (S. aureus) and gram‐negative (E. coli) bacteria was tested. The optimum antibacterial activity against S. aureus and E. coli was observed in the PBAT composite film with 20% of Juniperus communis L. plant extract. However, it can be supposed that the food packaging characteristics are improved by adding Juniperus communis L. plant extract to the PBAT. [ABSTRACT FROM AUTHOR]

Objective: Providing accurate prenatal prognostication for expectant parents is challenging due to limited literature on factors impacting outcomes in children with congenital aqueductal stenosis (CAS). This study stratified CAS patients into isolated or complex categories (presence of additional intra‐ or extra‐cranial anomalies or genetic syndromes) and evaluated both short‐ and long‐term outcomes. Additionally, the role of ventricular rupture was assessed. Methods: This was a single center retrospective‐cohort study of CAS patients who underwent fetal MRI over a 10‐year period. Results: Of 140 patients with CAS, 107 (76%) were complex and 33 (24%) were isolated. There were no differences in the size of ventricular enlargement or incidence of ventricular rupture between the two groups. 14 pregnancies were terminated, 9 experienced fetal demise/stillbirth, and there were 21 post‐natal deaths. Outcomes at the time of hospital discharge were available for 86 patients and long‐term follow‐up data for 64. CSF diversion (via ventriculoperitoneal shunt) was performed in 95% of complex and 71% of isolated CAS patients. Acutely, no differences were noted in seizures (complex: 10%; isolated: 18%) or respiratory support but there was an increased risk for feeding support. Risks for non‐ambulatory status (complex: 32% vs. isolated: 0%), epilepsy (complex: 56% vs. isolated: 19%) and long‐term gastrostomy tube assisted feeding (complex: 25.5% vs. isolated: 0%) were significantly greater with complex CAS. The presence of rupture did not impact clinical outcome. Conclusion: Poor clinical outcome was associated with complex CAS. Ventricular rupture alone did not portend a poor outcome. Prenatal counseling can tailor prognostication by CAS type. [ABSTRACT FROM AUTHOR]

The article explores the decolonization of anthropology in Japan through dialogues among scholars from diverse academic, political, and ethnic backgrounds. Topics discussed include the historical impact of the Japanese Empire on Indigenous cultures, the role of anthropology in addressing colonial legacies, and the ongoing struggles for Indigenous recognition in Japan, particularly regarding the Ainu and Okinawan peoples.

Host selection behaviour plays a pivotal role in determining the success of parasitoids, especially in environments where host quality varies. In heterogeneous environments, parasitoids frequently encounter hosts that are infected.We conducted experiments to ascertain whether the ecto‐parasitoid Bracon brevicornis can differentiate between healthy caterpillars and those infected with Bacillus thuringiensis (Bt) and examined the implications of this host selection behaviour.In an olfactometer choice assay, B. brevicornis avoided Bt‐infected Spodoptera litura hosts. In a no‐choice assay, the female parasitoid displayed a lower paralysis rate on infected hosts, indicating a strong selection behaviour. Furthermore, we explored the impact of infection duration by exposing female wasps to larvae infected for 24, 48 and 72 h with Bt. Both choice and no‐choice assays demonstrated that female B. brevicornis refrains from ovipositing on infected larvae, regardless of the infection duration.Direct exposure to Bt through consumption did not affect the fitness of the tested parasitoid wasp. However, post‐24‐h Bt infection, host larvae showed an increased total hemocyte density, particularly high phagocytic cell numbers, and enhanced melanization, rendering the host larva unsuitable for parasitoid development.Taken together, our study underscores that parasitoids exhibit robust host selection behaviour by actively avoiding infected hosts. This insight is valuable for devising new pest control strategies in agriculture that safeguard beneficial parasitoids. [ABSTRACT FROM AUTHOR]

This cross‐sectional study investigated nonconventional therapies for COVID‐19 in Trinidad, emphasizing the need for documentation supporting future pharmaceutical research. The survey, conducted from June 20 to July 19, 2022, garnered responses from 57 participants aged 18 and above, with 82.46% vaccinated. The majority (81%) utilized both conventional and nonconventional therapies, revealing insights for potential alternatives to traditional treatments. Conventional treatments, including antibiotics, Ivermectin, anti‐inflammatories, analgesics, bronchodilators, and cough/flu syrups, were frequently reported. Nonconventional therapies encompassed vitamins, minerals, supplements, and various plant and animal products. When participants used conventional therapies, either alone or in combination with nonconventional ones, 13.21% reported side effects. These included severe thirst, headache, nausea, drowsiness, and one case of weight gain. Conversely, those exclusively using nonconventional treatments reported no side effects. Encouragingly, nonconventional therapies demonstrated promising effects in managing COVID‐19, emphasizing the need for meticulous selection, research, and development of their bioactive compounds as potential alternatives to conventional therapies. [ABSTRACT FROM AUTHOR]

1,4‐Dihydropyridines (1,4‐DHPs) represent a versatile class of organic compounds derived from pyridines, recognized for their extensive synthetic applications and significant medical significances. Among the various synthetic methodologies available, the Hantzsch dihydropyridine synthesis is particularly notable as it provides a reliable approach to the production of these compounds. Recent advancements have markedly improved the synthetic pathways leading to Hantzsch dihydropyridines and their derivatives. This review aims to thoroughly examine the recent progress in the synthesis of 1,4‐DHPs, 1,8‐dioxodecahydroacridines (AD), and polyhydroquinolines (PHQ). Emphasis is placed on novel synthetic strategies reported in recent years, specifically those that employ multicomponent reactions involving aldehydes, β‐ketoesters, and ammonium salts. Furthermore, these reactions are catalyzed by various nanocatalysts, including magnetic nanoparticles, nanocomposites, metal oxides, functionalized nanoparticles, and other environmentally friendly nanobiomaterials. The application of nanocatalysts in these processes is underscored by their contributions to structural integrity and activity enhancement, indicative of a paradigm shifts towards more sustainable and efficient synthetic methodologies. This review consolidates and assesses various synthetic routes facilitated by nanocatalysts while elucidating their distinct roles in improving the efficiency and selectivity of 1,4‐DHP synthesis. Hence, this review may pave the way for advancements in Hantzsch reactions by employing nanomaterial catalysts for the sustainable production of 1,4‐DHP derivatives. [ABSTRACT FROM AUTHOR]

Poly(butylene adipate‐co‐terephthalate) (PBAT) is popular because of its low cost, biodegradability, good processing properties, flexibility, and mechanical features. In this study, we explore the potential of PBAT‐based bioplastics by adding AgVO3 nanorods with PBAT to reduce costs. We produced nanocomposite films of PBAT reinforced with 1, 3, and 5 wt% of AgVO3 nanorods using solvent casting. The inclusion of AgVO3 in the structure of PBAT was investigated through Fourier transform infrared spectroscopy, x‐ray diffraction, and scanning electron microscopy. The nanocomposite films demonstrate excellent properties, surpassing those of single‐component blends, enhancing mechanical properties, and improving the barrier properties of nanocomposite films. The water vapor transmission rate of AgVO3 reinforced (5 wt%) nanocomposite films improved by 42.45% compared to pure PBAT films. The tensile strength of the PBA‐3 film was 37.19 MPa, exhibiting higher strength than the films produced from clean PBAT (19.73 MPa). The AgVO3‐reinforced films demonstrated increased resistance to moisture and water, as indicated by their higher water contact angle values (88.04°). Food‐borne bacteria like Staphylococcus aureus and Escherichia coli have been stable to the antibacterial activity of the nanocomposites on the addition of AgVO3.The potential applications of these nanocomposite films in food packaging are promising, offering a sustainable and effective solution to food preservation. Highlights: The AgVO3‐filled poly(butylene adipate‐co‐terephthalate) (PBAT) nanocomposite films exhibit superior mechanical, barrier, and resistance to moisture and water compared to neat PBAT films.The water vapor transmission rate of the film is significantly enhanced, with a 42.45% enhancement in films reinforced with 5 wt% AgVO3.AgVO3‐filled PBAT nanocomposites demonstrate effective antibacterial activity against Escherichia coli and Staphylococcus aureus. [ABSTRACT FROM AUTHOR]

Polarization grading in AlGaN/GaN‐based high‐electron‐mobility transistors (HEMTs) is a promising device design option that can improve linearity, speed, power, and noise performance for use in millimeter‐wave applications. This work investigates the potential of compositionally graded HEMT heterostructures to enhance device breakdown through lateral electric field engineering while maintaining a high device cutoff frequency (fT) due to reduced longitudinal optical (LO) phonon scattering. The impact of polarization grading on electric field profile is compared with conventional gate‐integrated mini‐field plates (mini‐FPs). It is also observed that polarization grading can augment the efficacy of gate‐connected FPs, further enhancing performance. Using physics‐based 2D device simulations, it is demonstrated that polarization engineering via polarization grading enhances breakdown (VBD) while preserving high fT, resulting in a Johnson's figure of merit (JFOM = fT × VBD), that is, ≈2.4× that of a conventional abrupt‐junction HEMT. This improvement represents a significant advancement over the ≈1.25× to ≈2× increase achieved with the use of mini‐FPs alone in HEMTs. [ABSTRACT FROM AUTHOR]

Oral diseases are often associated with bacterial and fungal pathogens such as Staphylococcus aureus, Streptococcus mutans, Enterococcus faecalis, and Candida albicans. This research explored a novel approach to addressing these pathogens by synthesizing zinc oxide nanoparticles (ZnO NPs) coated with rutin (RT), a plant‐derived compound. The synthesized ZnO‐RT NPs were comprehensively characterized using UV‐Vis spectrophotometer, SEM, and EDAX techniques to confirm their structural composition. The antioxidant potential was assessed through free radical scavenging assays. Additionally, the antimicrobial activity of ZnO‐RT NPs was evaluated using a zone of inhibition assay against oral pathogens. Molecular docking studies with the Autodock tool were performed to elucidate the interactions between RT and the receptors of oral pathogens. The findings demonstrated that ZnO‐RT NPs exhibited robust free radical scavenging activity. Furthermore, they showed significant antimicrobial activity with a minimal inhibitory concentration of 40 μg/mL against oral pathogens. ZnO‐RT NPs also displayed dose‐dependent anticancer effects on human oral cancer cells at concentrations of 10, 20, 40, and 80 μg/mL. Mechanistic insights into the anticancer activity on KB cells revealed the upregulation of apoptotic genes. This study underscores the promising potential of ZnO‐RT NPs for dental applications due to their strong antioxidant, anticancer, and antimicrobial properties. These nanoparticles offer a hopeful prospect for addressing oral pathogen challenges and enhancing overall oral health. Summary: Zinc oxide‐tutin nanoparticle (ZnO‐RT NPs) exhibited robust free radical scavenging activity.It showed significant antimicrobial activity against oral pathogens.ZnO‐RT NPs also displayed dose‐dependent anticancer effects on human oral cancer cells.Mechanism action of ZnO‐RT NPs revealed the upregulation of apoptotic genes. [ABSTRACT FROM AUTHOR]

The influence of upper ocean dynamics on the acoustic field in the South Eastern Arabian Sea (SEAS) is studied using in situ oceanographic/acoustic measurements from a moored buoy, along with satellite‐derived and climatological data sets. Upper‐ocean variability at the site is quantified using Mixed Layer Depth (MLD), Isothermal Layer Depth (ILD), Barrier Layer Thickness (BLT), Maximum Spice Depth (MSD), and Sonic Layer Depth (SLD), along with surface variability factors such as Sea Surface Temperature, Sea Surface Salinity, Spice, and Sea Level Anomaly. The mixed layer acoustic duct (MLAD) varies from 2 to 100 m, with BLT varying from 5 to 99 m, and a mean SLD of 43 m. A thick transition layer connects the mixed layer with the thermocline during winter. The observations reveal that maximum SLD, MSD, and BLT occurred during January–March. Unlike other seasons when SLD follows MLD, winter SLD is influenced by BLT, suggesting strong salinity stratification due to low‐salinity water intrusion from the Bay of Bengal by East India Coastal Current. During these months, the SLD varies from 80 to 100 m, with the corresponding minimum cut‐off frequency varying from 300 to 200 Hz. Results are correlated with estimated Sound Pressure Level (SPL) from Ambient Noise Measurements during November 2018 to November 2019. SPL variation follows SLD for low and mid‐frequencies, with the highest SPL noted during January‐February. Acoustic propagation simulations at 250 and 1,000 Hz revealed features like acoustic duct leakage and channeling, indicating energy transfers between the surface acoustic duct and deeper layers. Plain Language Summary: The surface duct occurs just below the sea surface whenever the processes of stirring by the wind and convection caused by surface cooling and evaporation produce a layer of quasi‐isothermal water called a mixed layer. Studies show a strong association between SLD and MLD over most parts of the global ocean, including the Arabian Sea. Salinity variability plays a crucial role in the formation of the barrier layer and its effect on SLD. Recent studies (Colosi & Rudnick, 2020, https://doi.org/10.1121/10.0002174; Richards & Colosi, 2023, https://doi.org/10.1121/10.0021311) have shown the effect of salinity on SLD, including considerations of ocean spice over the North Pacific Ocean. This study attempts to understand this aspect using moored‐buoy observation, satellite‐derived and climatological data. An Acoustic Recorder is mounted on an OMNI‐buoy mooring at 550 m depth, in the SEAS to measure the sound field. The influence of Upper Ocean dynamics on MLAD and its effects on acoustic propagation is examined through modeling. The variability in derived SPL over a year is addressed using SLD and acoustic propagation simulations. The link between oceanographic aspects and acoustic fields in warm tropical waters (i.e., SEAS) is brought out, which would be helpful in conducting at sea acoustic experiments and trials. Key Points: Evaluated the impact of upper ocean dynamics on under water acoustics at south western Bay of BengalImpact of Sonic layer variability on acoustic propagation at different frequencies using deep ocean Ambient Noise Measurement System [ABSTRACT FROM AUTHOR]

The gamma radiolytic degradation behavior of n‐dodecane (n‐DD) was investigated under conditions both with and without the presence of nitric acid. The physicochemical property alterations due to radiolysis were quantified and compared against an unirradiated system. Compositional changes in n‐DD post radiolysis was measured, and the degraded n‐DD was characterized using Fourier‐transform infrared (FT‐IR) spectroscopy, gas chromatography (GC), and gas chromatography–mass spectrometry (GC–MS) analysis. The presence of nitric acid was observed to accelerate the radiolytic degradation of n‐DD. The extent of diluent degradation caused by gamma irradiation was assessed through the retention behavior of uranium [U(VI)], plutonium [Pu(IV)], and zirconium [Zr(IV)] in 1.1 M tri‐n‐butyl phosphate (TBP) in irradiated diluent. Furthermore, the effectiveness of hydrazine carbonate (HC) as a solvent wash reagent for the removal of diluent degradation products was evaluated. [ABSTRACT FROM AUTHOR]

Despite various clinical options, human anterior cruciate ligament (ACL) lesions do not fully heal. Biomaterial‐guided gene therapy using recombinant adeno‐associated virus (rAAV) vectors may improve the intrinsic mechanisms of ACL repair. Here, we examined whether poly(sodium styrene sulfonate)‐grafted poly(ε‐caprolactone) (pNaSS‐grafted PCL) films can deliver rAAV vectors coding for the reparative basic fibroblast growth factor (FGF‐2) and transforming growth factor beta (TGF‐β) in human mesenchymal stromal cells (hMSCs) as a source of implantable cells in ACL lesions. Efficient and sustained rAAV‐mediated reporter (red fluorescent protein) and therapeutic (FGF‐2 and TGF‐β) gene overexpression was achieved in the cells for at least 21 days in particular with pNaSS‐grafted PCL films relative to all other conditions (up to 5.2‐fold difference). Expression of FGF‐2 and TGF‐β mediated by rAAV using PCL films increased the levels of cell proliferation, the DNA contents, and the deposition of proteoglycans and of type‐I and ‐III collagen (up to 2.9‐fold difference) over time in the cells with higher levels of transcription factor expression (Mohawk, Scleraxis) (up to 1.9‐fold difference), without activation of inflammatory tumor necrosis alpha especially when using pNaSS‐grafted PCL films compared with the controls. Overall, the effects mediated by TGF‐β were higher than those promoted by FGF‐2, possibly due to higher levels of gene expression achieved upon rAAV gene transfer. This study shows the potential of using functionalized PCL films to apply rAAV vectors for ACL repair. [ABSTRACT FROM AUTHOR]

Aims and Objectives. Admission in the intensive care unit is highly stressful, for both the child and family. This study aimed to identify the factors influencing the nurse‐parent partnership in the pediatric intensive care units. Methods. The data were collected from 71 ICU nurses through a web‐based survey by the Pediatric Nurse‐Parent Partnership (NPP) Scale, Wong and Law Emotional Intelligence (EI) Scale, and patient‐centered communication (PCC) proficiency by Park and Oh's. Descriptive and inferential statistics were used to analyze the data. Results. The mean scores for NPP, EI, and PCC skills were 67.91 ± 9.62, 55.16 ± 5.77, and 33.38 ± 4.81, respectively. There was a positive correlation between NPP, EI (r = 0.71, p < 0.001), and PCC skills (r = 0.59, p < 0.001). In hierarchical multiple regression analysis, EI (p < 0.01) and PCC skills (p = 0.05) were the two stronger primary variables influencing NPP than the general variables such as gender, children, and an additional qualification in pediatric nursing with higher variance (59% vs 14%). Conclusion. The findings of the study supported that nurses' EI and PCC skills as well as additional qualification or training in pediatric nursing were the primary factors influencing nurse‐parent partnership in intensive care settings. Thus, effective intervention programs focusing on these factors should be initiated to strengthen NPP. [ABSTRACT FROM AUTHOR]

Triboelectric nanogenerators (TENGs) have become reliable green energy harvesters by converting biomechanical motions into electricity. However, the inevitable charge leakage and poor electric field (EF) of conventional TENG result in inferior tribo‐charge density on the active layer. In this paper, TiO2‐MXene incorporated polystyrene (PS) nanofiber membrane (PTMx NFM) charge trapping interlayer is introduced into single electrode mode TENG (S‐TENG) to prevent electron loss at the electrode interface. Surprisingly, this charge‐trapping mechanism augments the surface charge density and electric output performance of TENGs. Polyvinylidene difluoride (PVDF) mixed polyurethane (PU) NFM is used as tribo‐active layer, which improves the crystallinity and mechanical property of PVDF to prevent delamination during long cycle tests. Herein, the effect of this double‐layer capacitive model is explained experimentally and theoretically. With optimization of the PTMx interlayer thickness, S‐TENG exhibits a maximum open‐circuit voltage of (280 V), short‐circuit current of (20 µA) transfer charge of (120 nC), and power density of (25.2 µW cm−2). Then, this energy is utilized to charge electrical appliances. In addition, the influence of AC/DC EF simulation in wound healing management (vitro L929 cell migration, vivo tissue regeneration) is also investigated by changing the polarity of trans‐epithelial potential (TEP) distribution in the wounded area. [ABSTRACT FROM AUTHOR]

Summary: Mobile networks have advanced in many fields to share information with others. But finding the required resources for each user to share the data is a complex task because of the moving environment. So, the present research article has introduced a novel Chimp‐based Random Forest Peer Identification Framework (CbRFPIF) in the mobile environment. Initially, the required nodes were designed dynamically in the moving background. Hence, the designed wireless moving environment has included sender, peer, and receiver nodes. Moreover, the Chimp fitness model predicted the users' requested resources in the primary stage, then the nearest peer and the user locations were predicted. Consequently, the requested resource by users was distributed to the particular closest peers, and the peer forwarded the data to the specific users. Finally, the planned model is simulated in the NS2 environment, and the communication parameters were calculated and compared with other associated models, which gained the highest throughput and search rate. [ABSTRACT FROM AUTHOR]

The design of structures with a large radius of curvature is challenging because fiber‐reinforced composite materials have low resistance to delamination in the direction perpendicular to their thickness. These structures are commonly found in a wide variety of structural components that are used in the wind turbine and aviation industries. The objective of this study is to conduct an experimental investigation into the efficacy of incorporating milled glass fiber, cellulose nanoparticles, and carbon nanoparticles as fillers into an epoxy matrix to improve the resistance to delamination of glass/epoxy curved laminates and thereby inhibit crack growth. In contrast to the baseline samples, curved samples containing 3% cellulose nanoparticles demonstrated enhanced curved beam strength and interlaminar tensile strength by 4.95% and 3.82%, respectively. Additionally, filler‐loaded samples exhibited reduced delamination and fracture propagation damage compared with baseline samples. The adhesion between the epoxy matrix and infill was investigated by means of Fourier transform infrared analysis. In addition, live photographic images and fractured micrographs were correlated with mechanical findings in order to assess delamination suppression and damage processes in both the arm and arc directions. [ABSTRACT FROM AUTHOR]

An unusual condition of the eye called diabetic retinopathy affects the human retina and is brought on by the blood's constant rise in insulin levels. Loss of vision is the result. Diabetic retinopathy can be improved by receiving an early diagnosis to prevent further damage. A cost‐effective method of accumulating medical treatments is through appropriate DR screening. In this work, deep learning framework is introduced for the accurate classification of retinal diseases. The proposed method processes retinal fundus images obtained from databases, addressing noise and artifacts through an improved median filter (ImMF). It leverages the UNet++ model for precise segmentation of the disease‐affected regions. UNet++ enhances feature extraction through cross‐stage connections, improving segmentation results. The segmented images are then fed as input to the improved gannet optimization‐based capsule DenseNet (IG‐CDNet) for retinal disease classification. The hybrid capsule DenseNet (CDNet) classifies disease and is optimized using the improved gannet optimization algorithm to boost classification accuracy. Finally, the accuracy and dice score values achieved are 0.9917 and 0.9652 on the APTOS‐2019 dataset. [ABSTRACT FROM AUTHOR]

Background Purpose Classical antiemetics that target the serotonin system may not be effective in treating certain nausea and vomiting conditions like cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS). As a result, there is a need for better therapies to manage the symptoms of these disorders, including nausea, vomiting, and anxiety. Cannabis is often used for its purported antiemetic and anxiolytic effects, given regulation of these processes by the endocannabinoid system (ECS). However, there is considerable evidence that cannabinoids can also produce nausea and vomiting and increase anxiety in certain instances, especially at higher doses. This paradoxical effect of cannabinoids on nausea, vomiting, and anxiety may be due to the dysregulation of the ECS, altering how it maintains these processes and contributing to the pathophysiology of CVS or CHS.The purpose of this review is to highlight the involvement of the ECS in the regulation of stress, nausea, and vomiting. We discuss how prolonged cannabis use, such as in the case of CHS or heightened stress, can dysregulate the ECS and affect its modulation of these functions. The review also examines the evidence for the roles of ECS and stress systems' dysfunction in CVS and CHS to better understand the underlying mechanisms of these conditions. [ABSTRACT FROM AUTHOR]

Elastomers based on cross‐linked bottlebrush polymers combine an extreme softness at low strains with a strain‐stiffening effect, which makes them attractive as active components in dielectric elastomer actuators (DEA). Their main disadvantage concerns the small relative permittivity, which is about 3.5, requiring relatively high driving voltage in actuators. We synthesized a bottlebrush polymer elastomer with polar brushes, which exhibit an enhanced dielectric permittivity of 4.4. Anionic ring‐opening polymerization of a polar cyclosiloxane gave telechelic polar brushes, while ring‐opening polymerization of a norbornene macromonomer gave a bottlebrush polymer which was cross‐linked to elastomers by a thiol‐ene reaction. Elastomers with a small elastic modulus below 100 kPa, strain at break exceeding 100 %, attractive elasticity, and small mechanical loss factors (tanδ) were achieved. Temperature‐dependent impedance measurements revealed a transition temperature of −95 °C and an interfacial polarization. The multigram scale synthesis demonstrates the potential for scaling up, which opens the door to broader applications of these materials beyond actuators, such as capacitive sensors, batteries, and electroluminescent devices. Notably, these devices operate at extremely low voltages where the dielectric breakdown does not limit their functionality, but still, the softness and the increased dielectric permittivity are a plus. [ABSTRACT FROM AUTHOR]

The Mycobacterium tuberculosis trifunctional enzyme (MtTFE) is an α2β2 tetrameric enzyme in which the α‐chain harbors the 2E‐enoyl‐CoA hydratase (ECH) and 3S‐hydroxyacyl‐CoA dehydrogenase (HAD) active sites, and the β‐chain provides the 3‐ketoacyl‐CoA thiolase (KAT) active site. Linear, medium‐chain and long‐chain 2E‐enoyl‐CoA molecules are the preferred substrates of MtTFE. Previous crystallographic binding and modeling studies identified binding sites for the acyl‐CoA substrates at the three active sites, as well as the NAD binding pocket at the HAD active site. These studies also identified three additional CoA binding sites on the surface of MtTFE that are different from the active sites. It has been proposed that one of these additional sites could be of functional relevance for the substrate channeling (by surface crawling) of reaction intermediates between the three active sites. Here, 226 fragments were screened in a crystallographic fragment‐binding study of MtTFE crystals, resulting in the structures of 16 MtTFE–fragment complexes. Analysis of the 121 fragment‐binding events shows that the ECH active site is the 'binding hotspot' for the tested fragments, with 41 binding events. The mode of binding of the fragments bound at the active sites provides additional insight into how the long‐chain acyl moiety of the substrates can be accommodated at their proposed binding pockets. In addition, the 20 fragment‐binding events between the active sites identify potential transient binding sites of reaction intermediates relevant to the possible channeling of substrates between these active sites. These results provide a basis for further studies to understand the functional relevance of the latter binding sites and to identify substrates for which channeling is crucial. [ABSTRACT FROM AUTHOR]

Background: Neurocognitive health is influenced by multiple modifiable and non‐modifiable lifestyle factors. Machine learning tools offer a promising approach to better understand complex models of cognitive function. We used extreme gradient boosting (XG Boost), an algorithm of decision‐tree modeling, to analyze the association between 15 late‐life lifestyle and demographic factors with episodic memory performance. Method: Our dataset consisted of 2247 participants from the KHANDLE and STAR cohorts. Participants included 841 men and 1406 women, an ethnoracial diversity of 413 Asian, 987 Black, 349 Latinx, and 496 White adults with age range 54‐90 (mean = 74). XG Boost models of continuous episodic memory performance were trained and evaluated using a random training/test split of the data. Trained models were used to plot relative factor importance and individual Shapley values for each participant, over the entire sample and stratified by gender. Result: We present XG boost ranking of factors for episodic memory in the full set and stratified by gender. The relative importance of factors for baseline episodic memory (Fig. 1) showed education, income range and sleep quality as the most important variables in both full and sex‐stratified models. In the full sample, gender was highly important and ethnoracial categories showed the least importance. Shapley values for each variable (Fig. 2) showed gender, education, income range, volunteering, and sleep quality were paramount contributors to episodic memory performance. In gender‐stratified models, education, volunteering, income, and sleep quality were of most importance. Exercise contributed modestly. Negative factors like smoking, excessive alcohol and TBI had moderate impacts. Ethnoracial background had minimal influence, except for White (full set) and Latinx (male and female). Shapley dependency on memory in the full set (Fig. 3) showed a plateau effect for education at around 12 years of schooling; linearly increasing effect with no plateau for income; an inverted "U" dependence on sleep duration; and a nonlinear relation with sleep quality requiring more investigation. Conclusion: Decision trees may be a promising approach to determining the relative contributions of multiple life exposure factors that affect cognitive performance in a large and diverse cohort. This may help to inform ADRD preventive interventions. [ABSTRACT FROM AUTHOR]

Emerging millimeter‐wave wireless communication systems require high‐performance radio frequency switches to support advanced functionality such as frequency agility, circuit reconfigurability, and beamforming. Ferroelectric (FE)‐gated AlGaN/GaN high‐electron‐mobility transistors (HEMTs) (FeHEMTs) are developed and demonstrated as a technology option for this important role. AlGaN/GaN HEMT heterostructures grown by metal‐organic chemical vapor deposition are augmented with a FE gate stack comprising atomic layer deposition‐grown HfZrO2. In addition, highly doped regrown source and drain Ohmic contacts are integrated into an improved fabrication process flow. This improved process leads to contact resistances of 0.105 Ω mm and a reduction in switch on‐resistance as compared to prior reports, as well as drain current densities of 1 A mm−1 and measured ft = 54 GHz for gate lengths of 0.1 μm. The improved contact and gate length scaling makes FeHEMTs a promising candidate for mm‐wave switch applications achieving a reported switch figure of merit of fCO = 1.55 THz. [ABSTRACT FROM AUTHOR]

Aim: To compare the effects of Yoga with traditional exercise on the mobility and functional capacity of individuals with ankylosing spondylitis (AS). Methods: The participants of the study were recruited at the rheumatology department, adhering to the study's inclusion and exclusion criteria. Participants were randomized into two groups (Group A – Yoga, and Group B – exercise).The candidates participated in an 8‐week intervention consisting of 3 weekly sessions of either Yoga or Exercise intervention. Outcomes were collected at pre‐treatment, at 8 weeks, and at 12 weeks. Results: The within‐group comparison showed an improvement in all outcome measures with p <.05 between post‐treatment and the follow‐up. In the yoga group, there was an improvement in the measures of BASMI (p =.001), BASFI (p =.005), PSQI (p =.021), CE (p =.053) and NPRS (p =.001). Similarly, in the exercise group, there was an improvement in BASMI (p =.002), BASFI (p =.003), PSQI (p =.010), CE (p =.004) and NPRS (p =.001). In the between group comparison at post‐treatment, there were no statistically significant differences in BASMI (yoga = 3.0 ± 1.50, exercise = 2.3 ± 1.38), PSQI (yoga = 5.3 ± 1.50, exercise = 4.9 ± 1.17) and NPRS (yoga = 1.3 ± 2.22, exercise = 0.4 ± 0.50) CE (yoga = 4.0 ± 1.18, exercise = 3.4 ± 0.96), BASFI (yoga = 1.8 ± 2.14, exercise = 2.1 ± 1.87). Conclusion: The results demonstrated a statistically significant improvement in within‐group scores of mobility, functional capacity, sleep quality and pain in AS patients of both intervention programs but there were no significant differences between the groups. [ABSTRACT FROM AUTHOR]

We propose a method for increasing the bandwidth of a substrate‐integrated‐waveguide (SIW) cavity‐backed antenna with taper‐based microstrip SIW transition feeding. For radio transmission, a circular slot is etched on top of the SIW cavity. For optimal antenna design, the slot is etched slightly away from the cavity center to generate circularly polarized waves. Simulations show a wide axial ratio bandwidth of 7.860% between 11.02 GHz and 11.806 GHz. Experimental results confirm a similar wide axial ratio bandwidth of 4.9% between 10.8 GHz and 11.35 GHz. An SIW feed from an inductive window excites the radiating circular slot, resulting in a simulated wide impedance range of 1.548 GHz (10.338 GHz–11.886 GHz) and bandwidth of 13.93%. Experimental results show a wide impedance of 2.08 GHz (10.2 GHz–12.08 GHz) and bandwidth of 18.84%. The SIW cavity‐backed antenna creates a unidirectional pattern, leading to gains of 6.61 dBi and 7.594 dBi in simulations and experiments, respectively. The proposed antenna was fabricated on a Rogers RT/Duroid 5880 substrate, and the reflection coefficient, radiation patterns, and gains were tested and compared using a computer simulator. The developed broadband antenna seems suitable for X‐band applications. [ABSTRACT FROM AUTHOR]

Cephalometric analysis has an important and essential role to treat the patients with craniofacial and dentofacial deformities. Cephalometric analysis is a relationship of human geometry which can be quantified and derived from the linear and angular measurements. To treat any patient, such analysis is required to be performed on the Head X‐ray image of the patient. The objective of the proposed work is to detect cephalometric landmarks automatically on CT (computational tomography) images. Twenty cephalometric landmarks were automatically localized on 100 CT scans using hybrid coarse‐to‐fine computational method. The mean error for landmark detection was computed as 2.88 mm and standard deviation of 1.85 mm. The highest detection rate for cephalometric landmarks was received as 100% for Nasion landmark under 4‐mm error and the highest detection rate was received as 99% for Nasion landmark under 3‐mm error. The less number of datasets were used for the training and higher number of datasets were used for the testing. Compared to the literature methods, our method used higher number of datasets to demonstrate the accuracy of the proposed method. [ABSTRACT FROM AUTHOR]

Introduction: Autoimmune encephalitis (AE) comprises a heterogeneous group of autoantibody‐mediated disorders targeting the brain parenchyma. Therapeutic plasma exchange (TPE), one of several first‐line therapies for AE, is often initiated when AE is suspected, albeit prior to an established diagnosis. We sought to characterize the role of TPE in the treatment of suspected AE. Methods: A single‐center, retrospective analysis was performed of adults (≥18 years) who underwent at least one TPE procedure for "suspected AE." The following parameters were extracted and evaluated descriptively: clinicopathologic characteristics, treatment course, TPE‐related adverse events, outcomes (e.g., modified Rankin scale [mRS]), and diagnosis once investigation was complete. Results: A total of 37 patients (median age 56 years, range 28–77 years, 62.2% male) were evaluated. Autoimmune antibody testing was positive in serum for 43.2% (n = 16) and cerebrospinal fluid for 29.7% (n = 11). Patients underwent a median of five TPE procedures (range 3–16), with 97.3% (n = 36) via a central line and 21.6% (n = 8) requiring at least one unit of plasma as replacement fluid. Fifteen patients (40.5%) experienced at least one TPE‐related adverse event. Compared with mRS at admission, the mRS at discharge was improved in 21.6% (n = 8), unchanged in 59.5% (n = 22), or worse in 18.9% (n = 7). Final diagnosis of AE was determined to be definite in 48.6% (n = 18), probable in 8.1% (n = 3) and possible in 27.0% (n = 10). Six (16.2%) patients were ultimately determined to have an alternate etiology. Conclusion: Empiric TPE for suspected AE is generally well‐tolerated. However, its efficacy remains uncertain in the absence of controlled trials, particularly in the setting of seronegative disease. [ABSTRACT FROM AUTHOR]

Alzheimer's disease (AD) is a progressive decline in cognitive ability and behavior which eventually disrupts daily activities. AD has no cure and the progression rate varies unlikely. Among various causative factors, heavy metals are reported to be a significant hazard in AD pathogenesis. Metal‐induced neurodegeneration has been focused globally with thorough research to unravel the mechanistic insights in AD. Recently, heavy metals suggested to play an important role in epigenetic alterations which might provide evidential results on AD pathology. Epigenetic modifications are known to play towards novel therapeutic approaches in treating AD. Though many studies focus on epigenetics and heavy metal implications in AD, there is a lack of research on heavy metal influence on epigenetic toxicity in neurological disorders. The current review aims to elucidate the plausible role of cadmium (Cd), iron (Fe), arsenic (As), copper (Cu), and lithium (Li) metals on epigenetic factors and the increase in amyloid beta and tau phosphorylation in AD. Also, the review discusses the common methods of heavy metal detection to implicate in AD pathogenesis. Hence, from this review, we can extend the need for future research on identifying the mechanistic behavior of heavy metals on epigenetic toxicity and to develop diagnostic and therapeutic markers in AD. [ABSTRACT FROM AUTHOR]

The current investigation uses biodiesel extracted from Moringa oleifera seeds in a diesel engine. M. oleifera biodiesel is prepared via conventional transesterification with standard conditions (60°C reaction temperature, 120 min reaction time, 1% by wt. catalyst, and 7.5:1 molar ratio). The test engine is a single‐cylinder air‐cooled naturally aspirated direct injection diesel engine. The test engine for experimentation is operated at 100% load with different engine speeds ranging from 1000 to 2400 rpm. Emissions characteristics were analyzed at different engine speeds. Results were interesting as the MB10 blend (10% M. oleifera biodiesel + 90% diesel) lowered the smoke by 24% and hydrocarbon by 10.34% with respect to neat diesel. Almost all the test fuels have higher HC profiles at reduced engine speeds. The MB20 blend lowered the CO profile to the CO profile of diesel fuel by about 0.84%. However, it can be observed that the MB10 blend's average CO profile is improved by 1.97% than mineral diesel. These results are compromised with higher CO and NOx profiles of 2.4% and 8.9%, respectively. [ABSTRACT FROM AUTHOR]

Fruits and vegetables are nutritious and good in minerals, vitamins, and fib. Most fresh fruits and vegetables contain a minimum of 70% of moisture content which causes the formation of bacteria, fungi, and viruses to affect and cause the items to rot. But dried fruits contain only less than 20% of moisture content. So drying the fruits and vegetables helps to preserve the items for longer use without causing them to rot. Dried fruits have a great source of antioxidants and help in health benefits like improving blood flow, and reducing the effects of many diseases. Compared to fresh fruits, dried fruits are good in nutrition and have less weight for packaging and transportation usage. For drying materials, various types of solar dryers are used. Natural or open sun drying methods comparatively consume more than 12 h to dry material, whereas, direct and indirect drying methods would enhance the efficiency and dry the products quicker than open drying. For the consideration of quality drying and to increase efficiency, various modifications of solar dryers are designed and fabricated. In this review, we discussed the most appropriate developments in the drying of food items, required phase change materials (PCMs), performance, and environmental analysis of SD, and also reported the various designs of the solar drying techniques. [ABSTRACT FROM AUTHOR]

Recently, a mix of traditional and modern approaches have been proposed to detect brain abnormalities using bio‐signal/bio‐image‐assisted methods. In hospitals, most of the initial/scheduled assessments consider the bio‐signal‐based appraisal, due to its non‐invasive nature and low cost. Further, brain bio‐signal scans can be recorded using a single/multi‐channel electrode setup, which is further evaluated by an experienced doctor, as well as computer software, to identify the nature and severity of abnormality. In this paper, we describe the development of a system for computer supported detection (CSD) of schizophrenia using the electroencephalogram (EEG) signal collected with a 19‐channel electrode array. Schizophrenia is a mental illness that interferes with the way an individual thinks and behaves. It is characterised by psychotic symptoms such as hallucinations or delusions, negative symptoms such as decreased motivation or a lack of interest in daily activities and cognitive symptoms such challenges in processing information to make informed decisions or staying focused. This research has utilized 1142 EEGs (516 normal and 626 schizophrenia) with a frame length of 25 s (6250 samples) for investigation. The work initially converts the EEG signals to images using a spectrogram. Local configuration pattern features were extracted from the images thereafter, and 10‐fold validation technique was used wherein Student's t‐test and z‐score standardization were computed per fold. The highest accuracy of 97.20% was achieved with the K‐nearest neighbour (KNN) classifier. The results obtained confirm that the KNN classifier is helpful in the rapid detection of schizophrenia. This work is one of the first studies to extract local configuration pattern features from spectrogram images, yielding a high accuracy of 97.20%, with reduced computational complexity. [ABSTRACT FROM AUTHOR]

Objective: Brain 18F‐FDG PET/CT is a useful diagnostic in evaluating patients with suspected autoimmune encephalitis (AE). Specific patterns of brain dysmetabolism have been reported in anti‐NMDAR and anti‐LGI1 AE, and the degree of dysmetabolism may correlate with clinical functional status.18FDG‐PET/CT abnormalities have not yet been described in seronegative AE. Methods: We conducted a cross‐sectional analysis of brain18FDG‐PET/CT data in people with seronegative AE treated at the Johns Hopkins Hospital. Utilizing NeuroQ™ software, the Z‐scores of 47 brain regions were calculated relative to healthy controls, then visually and statistically compared for probable and possible AE per clinical consensus diagnostic criteria to previous data from anti‐NMDAR and anti‐LGI1 cohorts. Results: Eight probable seronegative AE and nine possible seronegative AE were identified. The group only differed in frequency of abnormal brain MRI, which was seen in all of the probable seronegative AE patients. Both seronegative groups had similar overall patterns of brain dysmetabolism. A common pattern of frontal lobe hypometabolism and medial temporal lobe hypermetabolism was observed in patients with probable and possible seronegative AE, as well as anti‐NMDAR and anti‐LGI1 AE as part of their respective characteristic patterns of dysmetabolism. Four patients had multiple brain18FDG‐PET/CT scans, with changes in number and severity of abnormal brain regions mirroring clinical status. Conclusions: A18FDG‐PET/CT pattern of frontal lobe hypometabolism and medial temporal lobe hypermetabolism could represent a common potential biomarker of AE, which along with additional clinical data may facilitate earlier diagnosis and treatment. [ABSTRACT FROM AUTHOR]

Dielectric elastomer transducers (DET) are promising candidates for electrically-driven soft robotics. However, the high viscosity and low yield stress of DET formulations prohibit 3D printing, the most common manufacturing method for designer soft actuators. DET inks optimized for direct ink writing (DIW) produce elastomers with high stiffness and mechanical losses, diminishing the utility of DET actuators. To address the antagonistic nature of processing and performance constraints, principles of capillary suspensions are used to engineer DIW DET inks. By blending two immiscible polysiloxane liquids with a filler, a capillary ink suspension is obtained, in which the ink rheology can be tuned independently of the elastomer electromechanical properties. Rheometry is performed to measure and optimize processibility as a function of filler and secondary liquid fraction. Including polar polysiloxanes as the secondary liquid produces a printed elastomer exhibiting a four-fold permittivity increase over commercial polydimethylsiloxane. The characterization and multimaterial printing into layered DET devices demonstrates that the immiscible capillary suspension improves the processability of the inks and enhances the properties of the elastomers, enabling actuation of the devices at comparatively low voltages. It is anticipated that this formulation approach will allow soft robotics to harness the full potential of DETs. [ABSTRACT FROM AUTHOR]

This study shows an effective approach for the synthesis of spirooxindole‐pyrans and bis‐spirooxindole‐pyrans derivatives using 5 mol % of [CMMIM][BF4] ionic liquid. The synthesis of a library of 28 derivatives was accomplished with impressive yields, ranging from 81 % to 97 %. The derivatives were successfully characterized by 1H‐NMR, 13C‐NMR, FT‐IR, and high‐resolution mass spectral techniques. In addition, the photophysical properties of 17 selected derivatives, including the molar extinction coefficient (ϵ) and the Stokes shift (Δυ̅), have been investigated. The values for spirooxindole‐pyrans vary between 14863 to 47372 and 5516 to 9766 cm−1, respectively. On the other hand, the corresponding values vary from 30871 to 57622 and 9199 to 13351 cm−1 for bis‐spirooxindole‐pyrans. Furthermore, the experimental data is supported by density functional theory (DFT) and time‐dependent DFT calculations. The theoretical studies conducted demonstrated a trend remarkably consistent with the experimental results. [ABSTRACT FROM AUTHOR]

Chalcone and triazole scaffolds have demonstrated a crucial role in the advancement of science and technology. Due to their significance, research has proceeded on the design and development of novel benzooxepine connected to 1,2,3‐triazolyl chalcone structures. The new chalcone derivatives produced by benzooxepine triazole methyl ketone and different aromatic carbonyl compounds. Product structures were established by various spectral techniques such as IR, 1H NMR, 13C NMR, and mass specrometric analysis. Among the tested compounds, two compounds exhibited exceptional antibacterial susceptibilities with MIC (Minimum inhibitory concentration) range of 3.59–10.30 μM against the tested S. aureus strain. Few of the compounds displayed superior antifungal activity against F. oxysporum with MIC value range from 3.25‐4.89 μM, when compared to fluconazole (MIC=3.83 μM). In addition, few derivatives demonstrated equivalent antitubercular action against H37Rv strain with MIC range of 2.16–4.90 μM. The capacity of one of the ligand to form a stable compound on the active site of CYP51 from M. tuberculosis (1EA1) was confirmed by docking studies. Additionally, the chalcone‐1,2,3‐triazole hybrids ADME (absorption, distribution, metabolism, and excretion), molecular characteristics, estimation of toxicity, and bioactivity scores were assessed. [ABSTRACT FROM AUTHOR]

Greener solvent mediated simple and efficient synthesis of 6‐hydroxy‐5‐(3‐(3‐hydroxy‐1,4‐dioxo‐1,4‐dihydronaphthalen‐2‐yl)‐2‐oxoindolin‐3‐yl)pyrimidine‐2,4(1H,3H)‐diones has been achieved through the one‐pot multicomponent condensation reaction between 2‐hydroxy‐1,4‐naphthoquinone, substituted isatin and barbituric acid/thiobarbituric acid/1,3‐dimethylbarbituric acid using ethanol‐water as a solvent without any catalyst at room temperature has been described. Molecular docking studies have been performed with Akt kinase enzyme protein which helped to rationalize the binding energy of all the synthesized compounds. The docking of compound 4d, with human Akt kinase enzyme showed a good binding interaction with lowest binding energy. Based on the results from the molecular docking studies, the compound 4d was further studied for its in‐vitro anticancer activity against human breast cancer cells (MCF‐7) and human normal breast cells (HBL 100) by MTT assay which also proved the potential anticancer activity of 4d. [ABSTRACT FROM AUTHOR]

The broad mite, Polyphagotarsonemus latus (Banks), is an important phytophagous mite that causes extensive damage to a wide range of crop species across the world. Fenazaquin, a mitochondrial electron transport inhibitor (METI), is one of the commonly used acaricides for the management of P. latus. The response to fenazaquin selection over generations and the risk of development of resistance was estimated herein using a laboratory‐selected population of P. latus (FEN‐SEL). Repeated exposure to fenazaquin over generations resulted in decreased susceptibility (99.32 folds) as compared to the unselected counterpart. FEN‐SEL took 26 generations for a 10‐fold increase in resistance with a realized heritability (h2) of 0.12 which indicated a low genetic variation and high phenotypic variation. Over a selection intensity of 20%–80% mortality, the generations required for a 10‐fold increase in LC50 for fenazaquin were 14.21–55.75, 7.75–30.41 and 5.33–20.91 at h2 values of 0.12, 0.22 and 0.32, respectively, with a constant slope of 2.39. The FEN‐SEL population also exhibited moderate levels of cross‐resistance to diafenthiuron, dicofol and spiromesifen and low cross‐resistance to propargite. The findings suggest a rational and rotational application of fenazaquin in the field to delay the development of resistance and to prolong its efficacy against P. latus. [ABSTRACT FROM AUTHOR]

Designing and developing high‐efficiency multifunctional catalysts materials is a significant challenge. In this view, we synthesized Graphene Quantum Dots (gQDs)/Gadolinium Manganese Oxide (GMO) nanostructures for photocatalytic dye degradation and hydrogen peroxide sensing. The structural, optical, composition, and morphology properties of the gQDs/GMO nanostructures were analyzed by using various analytical tools. The gQDs/GMO catalyst shows higher degradation efficiency compared to pure catalysts under visible light irradiation which is due to the large surface area, lower band gap, small amount of hydrogen peroxide (H2O2), and synergetic effect of gQDs/GMO. Furthermore, we extensively investigate the nonenzymatic H2O2 sensing and the gQDs/GMO catalytic materials show higher sensing behavior. From our results, the gQDs embedded in gadolinium‐modified manganese oxide (gQDs/GMO) serve as an efficient photocatalyst material for environmental pollutant degradation under visible light irradiation with and the sensitive electrocatalyst for nonenzymatic H2O2 sensing applications. [ABSTRACT FROM AUTHOR]

Due to extraordinary electronic and optoelectronic properties, large‐scale single‐crystal two‐dimensional (2D) semiconducting transition metal dichalcogenide (TMD) monolayers have gained significant interest in the development of profit‐making cutting‐edge nano and atomic‐scale devices. To explore the remarkable properties of single‐crystal 2D monolayers, many strategies are proposed to achieve ultra‐thin functional devices. Despite substantial attempts, the controllable growth of high‐quality single‐crystal 2D monolayer still needs to be improved. The quality of the 2D monolayer strongly depends on the underlying substrates primarily responsible for the formation of grain boundaries during the growth process. To restrain the grain boundaries, the epitaxial growth process plays a crucial role and becomes ideal if an appropriate single crystal substrate is selected. Therefore, this perspective focuses on the latest advances in the growth of large‐scale single‐crystal 2D TMD monolayers in the light of enhancing their industrial applicability. In the end, recent progress and challenges of 2D TMD materials for various potential applications are highlighted. [ABSTRACT FROM AUTHOR]

This study investigates the controllability problems for linear and nonlinear fractional control systems with multiple control delays in the context of the ψ$$ \psi $$‐Caputo fractional derivative. For the linear case, using the positive definiteness of the Gramian matrix, the necessary and sufficient conditions are obtained. For the nonlinear case, utilizing the iterative technique together with the completeness of the space, sufficient conditions for the existence of a solution are obtained. Just a few examples are included to make theoretical findings easier to grasp, and their respective graphs are plotted. [ABSTRACT FROM AUTHOR]

Composite materials are increasingly used in aircraft structural components with complex structures like L, C, or T shapes, which can cause delamination failure in the thickness direction under complex loading. This research focuses on the experimental investigation of the effect of different adhesive reinforcement phases with an adhesively bonded external patch to examine the residual strength and delamination resistance of repaired glass/epoxy curved samples. The damaged region in curved samples was repaired using adhesive reinforcement phases like neat epoxy, chopped glass fiber, and particulate glass fiber, along with adhesively bonded external patches like hybrid patches of glass/Kevlar (HP G/K), glass/carbon (HP G/C), and intraply patch carbon/Kevlar (IP C/K). The findings show that chopped glass fiber HP G/C patch-repaired curved samples had a curved beam strength (CBS) and interlaminar tensile strength (ILTS) recovery of 222.87% and 149.54%, respectively, as compared to damage area removed samples. In addition, it exhibited higher peak force, residual strength, and less elongation when compared to HP G/K and IP C/K patch-repaired curved samples. According to the findings of this research, composite angle brackets in aircraft structural components can be repaired utilizing an adhesively bonded HP G/C patch filled with chopped glass fiber at the dressed site. Highlights • The effect of patch hybridization on repaired curved laminates was studied. • Four-point bending test was conducted on indented and repaired samples. • Residual strength and delamination behavior were studied. • Chopped glass fiber HP G/C patch repaired samples had higher CBS and ILTS. • Delamination onset and propagation were assessed using Photographic images. [ABSTRACT FROM AUTHOR]

Composite structures with L, C, and T shape geometries are commonly used in the design of aerospace structural components. These complex structures are prone to delamination failure at the curved region. This study investigates the effect of thickness and recycled milled glass fiber fillers to improve the strength properties and delamination resistance of glass/epoxy composite angle brackets. Different thicknesses of 3.5 mm (16 layers), 5 mm (24 layers), and 6.5 mm (32 layers) specimens were subjected to four-point bending test with acoustic emission (AE) monitoring for evaluating damage resistance. Mechanical results reveal that the specimen with a higher thickness of 6.5 mm has better damage tolerance, followed by 3.5 and 5 mm angle brackets. Moreover, the location of AE signals and % of AE hits noticed the initiation and propagation of delamination in 5 mm thickness specimen at the earlier stage of loading. However, the curved beam strength and interlaminar tensile strength (ILTS) of 5 mm thickness specimen were improved by 31.02% and 19.2% respectively, through the incorporation of 2 wt% of fillers. Further, the interfacial adhesion between the fillers and epoxy matrix was studied using Fourier-transform infrared analysis to confirm the improvement of delamination resistance in 5 mm thickness specimen. Finally, the mechanical and AE results were well correlated with field emission scanning electron microscope images to characterize the damage mechanisms in composite angle brackets. Highlights • Effect of thickness on the delamination resistance of composites was studied. • Interlaminar properties of composite angle brackets were assessed. • Acoustic emission parameters were used to study the damage mechanisms. • Recycled milled glass fillers were employed to improve delamination resistance. • Mechanical and acoustic emission results were correlated with field emission scanning electron microscope images. [ABSTRACT FROM AUTHOR]

A novel‐shaped dual‐polarized low‐profile multiple‐input multiple‐output (MIMO) antenna with high isolation is proposed for 5G/WLAN application. An 8‐element MIMO antenna design comprises two unique planar radiators (chamfer, circular). Each radiator has dual feed and dual polarization characteristics. The prototype is fabricated with an FR‐4 dielectric substrate. A decoupling structure maintains desirable isolation for self‐isolated elements (≤ $\le $−12 dB) using substrate integrated waveguide stubs between inter‐ports and high isolation among the adjacent radiating elements (≤ $\le $−15 dB). The simulation was performed by using CST microwave studio. The simulated results of the proposed MIMO antenna are compared with the measurement results. Furthermore, ECC and DG are investigated. [ABSTRACT FROM AUTHOR]