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In order to maximize the electricity supply from clean energy sources, the goal of the smart power system is to unite all renewable energy sources. The goal of the present study is to use three optimization techniques, artificial rabbits optimization algorithm (ARO), grey wolf optimizer (GWO), and whale optimization algorithm (WOA), to reduce the cost of electricity (COE) while improving the reliability of the power supply for rural areas. While using the same control variables for the optimization methods and load profile, various hybrid system configurations are explored. Photovoltaic, wind turbine, fuel cell, and electrolyser systems are all involved in the proposed hybrid renewable system. The ARO methodology is more effective than the GWO, WOA, and PSO procedures in terms of net present cost (NPC) and cost of energy (COE) generation, according to data comparing the three optimization techniques with the traditional Particle Swarm Optimization (PSO) method. The proposed ARO reached a value of COE of 0.4412$/kWh compared to 0.4438$/kWh for GWO, 0.4443$/kWh for WOA, and 0.44378$/kWh for PSO. [ABSTRACT FROM AUTHOR]

Background: There is overwhelming evidence of improved patient outcomes as a result of early mobilization in the intensive care unit (ICU). However, several barriers of ICU mobility remain understated with reference to clinical roles. The purpose of this study is to investigate the perceived barriers of early mobility of critically ill patients among ICU healthcare providers. Methods: In this cross‐sectional study, the Mobilization Attitudes and Beliefs Survey (PMABS‐ICU) was administered to ICU healthcare providers using an online survey. The study investigated barriers related to knowledge, attitudes, and behaviors regarding ICU mobility practices. These barriers were compared among different ICU clinical roles. Results: The survey yielded a total number of 214 healthcare providers with 41% female and 59% male. Respiratory therapists reported the highest perceived barriers to ICU mobility (M 39, IQR 36, 43) % compared to physical therapists (who reported the lowest barriers), occupational therapists, nurses, and physicians (p ≤ 0.05). ICU healthcare providers' behavior towards ICU mobility such as perceived benefits and safety is ranked as the primary barrier (M 49, IQR 42, 52) %. Professional experience did not significantly vary among all groups. Conclusion: Our findings highlight that ICU healthcare providers' perceptions, including both potential benefits and safety concerns regarding mobility, are significant barriers to implement mobility practices. ICU mobility barriers should be tackled by providing education and training. A focused effort to include RTs and nurses could advance interdisciplinary ICU mobility practice and reduce associated barriers. [ABSTRACT FROM AUTHOR]

The human aryl hydrocarbon receptor (AhR), a ligand‐dependent transcription factor, plays a pivotal role in a diverse array of pathways in biological and pathophysiological events. This position AhR as a promising target for both carcinogenesis and antitumor strategies. In this study we utilized computational modeling to screen and identify FDA‐approved drugs binding to the allosteric site between α2 of bHLH and PAS‐A domains of AhR, with the aim of inhibiting its canonical pathway activity. Our findings indicated that nilotinib effectively fits into the allosteric pocket and forms interactions with crucial residues F82, Y76, and Y137. Binding free energy value of nilotinib is the lowest among top hits and maintains stable within its pocket throughout entire (MD) simulations time. Nilotinib has also substantial interactions with F295 and Q383 when it binds to orthosteric site and activate AhR. Surprisingly, it does not influence AhR nuclear translocation in the presence of AhR agonists; instead, it hinders the formation of the functional AhR‐ARNT‐DNA heterodimer assembly, preventing the upregulation of regulated enzymes like CYP1A1. Importantly, nilotinib exhibits a dual impact on AhR, modulating AhR activity via the PAS‐B domain and working as a noncompetitive allosteric antagonist capable of blocking the canonical AhR signaling pathway in the presence of potent AhR agonists. These findings open a new avenue for the repositioning of nilotinib beyond its current application in diverse diseases mediated via AhR. [ABSTRACT FROM AUTHOR]

This article, published in the Journal of the European Academy of Dermatology & Venereology, explores the impact of blood tumor clone frequency on the time to next treatment in mycosis fungoides (MF), the most common cutaneous T-cell lymphoma. The study used high-throughput DNA sequencing to identify T-cell clones in MF patients and determine the tumor clone frequency (TCF) in the total T-cell infiltrate. The findings suggest that an increased frequency of the malignant T-cell clone in the blood is correlated with reduced time to next treatment in MF patients. However, further validation in a larger cohort is needed to confirm these results. [Extracted from the article]

Introduction: Most kidneys from small pediatric donors are transplanted to adult recipients because of the perceived risk of surgical complications and graft thrombosis. In this study, we aim to demonstrate our favorable outcomes in transplanting pediatric kidneys from donors <15 k into pediatric recipients. Methods: This study retrospectively analyzes the outcomes of seven pediatric recipients of en block kidney transplants from pediatric donors weighing <15 kg performed at King Fahad Specialist Hospital‐Dammam from December 2014 to January 2018. Baseline characteristics of donors and recipients were collected. The incidences of surgical complication, immediate, and intermediate graft function were the primary outcomes. Results: The study included seven recipients monitored for a mean duration of 6.86 ± 1.35. Donors' and recipients' mean weights were 7.4 ± 3.2 kg and 20.7 ± 9.2 kg, respectively. Ureteric stricture occurred in one patient. There was a substantial improvement of 1‐year estimated glomerular filtration rate (eGFR) compared to the 1‐week mark (106.7 ± 26.38 mL/min. 1.73 m2 vs. 63.7 ± 22.92 mL/min/1.73 m2, p =.0069). The observed improvement in renal function persisted at the 5‐year mark and during the last follow‐up, with eGFR of 70.3 ± 40.7 mL/min/1.73 m2, and 79.8 ± 30.8 mL/min/1.73 m2, respectively. There was also increase of 27.9% in the size of the en bloc kidney observed at the 6 months. Conclusion: In a specialized transplant center with highly skilled surgeons, the utilization of en bloc kidney transplant from donors weighing less than 15 kg is an effective strategy for expanding the donor pool and ensuring favorable graft outcomes. [ABSTRACT FROM AUTHOR]

Background. Emergency departments suffer from authoritarian and manipulative leadership styles that affect team dynamics, emotional exhaustion, and quality patient care. However, little research specifically explores these toxic leadership effects on conflict management and nurses' organizational commitment. Objectives. This cross-sectional study aimed to assess the correlations between perceived toxic leadership, conflict resolution strategies, and commitment dimensions among emergency nurses while evaluating conflict tendencies as a mediating mechanism. Methods. A cross-sectional design that included multiple regression and mediation analyses was utilized. The sample consisted of 387 emergency nurses from five major Saudi hospitals surveyed using validated scales that measure perceived toxic leadership, conflict styles, and organizational commitment. Results. High prevalence rates for perceived authoritarian (77%), narcissistic (75%), and unpredictable (63%) leadership were reported. Increased toxicity was positively related to dominating and avoiding conflict styles but negatively related to integrating and compromising strategies. Toxic leadership is also associated with lower affective/normative commitment but higher continuance commitment. Conflict management partially mediated the leadership-commitment relationship, which explained 29% of the total effect. Finally, higher experience and education predicted greater perceived toxicity. Conclusions. The significant correlations between destructive leadership, adverse conflict, and reduced commitment in emergency nurses underscore the need for context-specific leadership training. Fostering supportive environments through multifaceted interventions can counteract toxicity impacts, impart constructive communication techniques, improve nurse well-being, and ensure high-quality patient care. As conflict tendencies and nurse characteristics influence susceptibility to detrimental leadership, tailored programs addressing experience levels are vital. [ABSTRACT FROM AUTHOR]

Microgrids are a new concept resulting from decentralized power sources, which have changed energy utility grid topography. As this promising field is penetrated, control must be streamlined immediately. This paper analyses key control mechanisms in energy utility networks, including centralized, decentralized, and distributed setups. The focus is on the auxiliary category as the various benefits and drawbacks of each approach is investigated. Information interchange architectures that enable multiple control techniques in the auxiliary control domain are examined using distributed energy networks. The research emphasizes the necessity of auxiliary control in ensuring reliable and effective utility infrastructure operation but notes the lack of a comprehensive scholarly reference. Additionally, the study explores key concerns in utility grids' auxiliary control mechanisms, emphasizing information‐sharing system limits. The goal is to demonstrate the importance of auxiliary control and evaluate its challenges, such as latency, which require new solutions for a seamless transition to a sustainable energy future through rigorous academic assessment. At the auxiliary level, complex, decentralized regulatory mechanisms are recommended to handle transmission channel bandwidth and operational overhead in energy utility networks. These innovative measures have the potential to transform the fundamental structure of our energy landscape, heralding in unprecedented efficiency and sustainability. [ABSTRACT FROM AUTHOR]

This article proposes a hybrid scheme of maximum power point tracking (MPPT) based on artificial neural network (ANN) and ripple current correlation (RCC). ANN model is established using the data generated through RCC MPPT. Scaled conjugate gradient ANN is applied to gauge the performance improvement. The proposed scheme is validated through simulations. For this, the proposed system is applied to three different environmental scenarios which are standard testing condition of a PV module, under variable irradiance condition, and variable temperature condition. It is established that the proposed system is well capable of tracking the maximum power point under various test conditions. [ABSTRACT FROM AUTHOR]

The cytochrome P450 1 A (CYP1A) subfamily enzymes are involved in the metabolic activation of several xenobiotics to toxic metabolites and reactive intermediates, resulting ultimately in carcinogenesis. Mercury and halogenated aromatic hydrocarbons (HAHs), typified by 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD), are persistent environmental pollutants involved in the modulation of aryl hydrocarbon receptor (AHR) gene battery, including cytochrome P450 (CYP) genes. We previously investigated the effect of coexposure to either inorganic or organic mercury (Hg+2 and MeHg) with TCDD on CYP1A1 in vitro. Thus, we examined the impact of coexposure to Hg+2 or MeHg and TCDD on AHR‐regulated genes (Cyp1a1/1a2) in vivo and in vitro. Therefore, male C57BL/6 mice were injected intraperitoneally with MeHg or Hg+2 (2.5 mg/kg) in the absence and presence of TCDD (15 μg/kg) for 6 or 24 h. The concentration‐dependent effect of MeHg was examined in murine hepatoma Hepa1c1c7 cells. In vivo, both MeHg and Hg2+ inhibited the TCDD‐mediated induction of Cyp1a1/1a2 mRNA levels. However, Only Hg2+ was able to inhibit the TCDD‐mediated induction at posttranscriptional levels of CYP1A1/1A2 protein and catalytic activity, suggesting differential modulation effects by Hg+2 and MeHg. In addition, the inhibitory role of HO‐1 (Heme oxygenase‐1) on CYP1A activity induced by TCDD was investigated using a HO‐1 competitive inhibitor, tin‐mesoporphyrin, that partially restored the MeHg‐mediated decrease in CYP1A1 activity. This study demonstrates that MeHg, alongside Hg2+, can differentially modulate the TCDD‐induced AHR‐regulated genes (Cyp1a1/1a2) at different expression levels in C57BL/6 mice liver and Hepa1c1c7 cells. [ABSTRACT FROM AUTHOR]

Ondansetron tablets that are directly compressed using crospovidone and croscarmellose as a synthetic super disintegrant are the subject of this investigation. A central composite, response surface, randomly quadratic, nonblock (version 13.0.9.0) 32 factorial design is used to optimize the formulation (two-factor three-level). To make things even more complicated, nine different formulation batches (designated as F1–F9) were created. There were three levels of crospovidone and croscarmellose (+1, 0, -1). In addition to that, pre- and postcompressional parameters were evaluated, and all evaluated parameters were found to be within acceptable range. Among all postcompressional parameter dispersion and disintegration time, in vitro drug release experiments (to quantify the amount of medication released from the tablet) and their percentage prediction error were shown to have a significant influence on three dependent variables. Various pre- and postcompression characteristics of each active component were tested in vitro. Bulk density, tap density, angle of repose, Carr's index, and the Hausner ratio were all included in this analysis, as were many others. This tablet's hardness and friability were also assessed along with its dimension and weight variations. Additional stability studies may be conducted using the best batch of the product. For this study, we utilised the Design-Expert software to select the formulation F6, which had dispersion times of 17.67 ± 0.03 seconds, disintegration times of 120.12 ± 0.55 seconds, and percentage drug release measurements of 99.25 ± 0.36 within 30 minutes. Predicted values and experimental data had a strong correlation. Fast dissolving pills of ondansetron hydrochloride may be created by compressing the tablets directly. [ABSTRACT FROM AUTHOR]

Nanotechnology is a rapidly evolving discipline as it has a wide variety of applications in several fields. They have been synthesized in a variety of ways. Traditional processes such as chemical and physical synthesis have limits, whether in the form of chemical contamination during synthesis operations or in subsequent applications and usage of more energy. Over the last decade, research has focused on establishing easy, nontoxic, clean, cost-effective, and environmentally friendly techniques for nanoparticle production. To achieve this goal, biological synthesis was created to close this gap. Biosynthesis of nanoparticles is a one-step process, and it is ecofriendly in nature. The metabolic activities of biological agents convert dissolved metal ions into nanometals. For biosynthesis of metal nanoparticles, various biological agents like plants, fungus, and bacteria are utilized. In this review paper, the aim is to provide a summary of contemporary research on the biosynthesis of gold nanoparticles and their applications in various domains have been discussed. [ABSTRACT FROM AUTHOR]

The coronavirus vaccine was developed to help overcome the COVID‐19 crisis. This study aimed to identify the cutaneous side effects secondary to Pfizer‐BioNTech and Oxford‐AstraZeneca COVID‐19 vaccines in the general population of Saudi Arabia and to list the risk factors for the development of cutaneous side effects. This cross‐sectional study was conducted in 2021, self‐administered surveys were distributed electronically through social media, and telephonic interviews were conducted with a sample size of 1000 participants. Data analysis was performed using Statistical Package for the Social Sciences. A total of 1021 patients (229 male and 722 female) aged 12 years or older were included. While 833 participants were medically free, 188 had chronic illnesses. While 802 participants were not taking any medications, 219 were taking medications regularly. Oxford‐Astra Zeneca and Pfizer BioNTech vaccines were administered to 319 and 702 participants, respectively. One‐hundred and twenty‐five participants previously had COVID‐19 infection and 407 were exposed to a PCR positive case of COVID. Six hundred and fifty‐nine patients (64.5%) reported experiencing injection site reactions: 606 (59.4%) had injection site pain, 168 (16.5%) had injection site swelling, and 107 (10.5%) had injection site redness. Only 51 patients (5%) experienced cutaneous side effects after injection. A significant association was found between chronic illnesses and cutaneous side effects post‐vaccine (9% vs. 4.1%; p value = 0.005). Patients on medications showed a higher rate of symptoms (8.2% vs. 4.1%; p value = 0.005). Age, gender, vaccine types, and history of COVID‐19 infection were not significantly associated with cutaneous side effects post‐vaccine. [ABSTRACT FROM AUTHOR]

The neurobehavioral syndrome known as spatial neglect, which could be a result of a brain tumor, is common but difficult to diagnose and manage. This case study describes the evaluation of spatial neglect syndrome psychologically in detail and also builds an initial discussion of the role of the Arabic language, which requires a right‐to‐left‐oriented spatial frame, to understand the severity of the symptoms. We report a case of spatial neglect syndrome after a brain tumor. A 7‐year‐old boy presented to the CDC clinics with a significant limitation of attention and very poor school achievement. The patient underwent several neuropsychological assessments, including an intellectual IQ test, social and adaptive behavior testing, attention deficit hyperactivity disorder testing, and a battery of neuropsychological tests to detect the presence of spatial neglect, as well as a psychological interview and observation. We present a 7‐year‐old boy with spatial neglect syndrome who visited the primary children's mental health department. The additional role of the Arabic language could have more of an impact on the symptoms and the proper rehabilitation intervention. After the proper diagnosis and rehabilitation intervention, the child showed a good outcome with regard to his attention and focusing skills as well as his school performance. [ABSTRACT FROM AUTHOR]

The aim of this study is to discover the impact of software security and e-mail security on overall cybersecurity among the students of Imam Abdulrahman Bin Faisal University in Dammam. Another main purpose to conduct this study is to know the level of knowledge students have in the developing countries about the cybersecurity and how much are they mindful of cyber-attacks and the level of awareness among the university students. Two important hypotheses were studied to discover their importance in awareness of cybersecurity. One is software security, and the other is e-mail security. A total of 11 relevant questions were drafted, and then these questions were distributed among the university students, and around 390 responded to the questionnaires. Statistical analysis was performed on the responses using tools. Initial tests such as validity and reliability test, feasibility test of a variable, correlation test, multicollinearity test, multiple regression, and Heteroskedasticity test were conducted using SPSS. And furthermore, multiple linear regression model and coefficient of determination, hypothesis test, ANOVA test, and partial test were conducted using ANOVA. The outcome of the analysis is software security variable (X1) that has a significant and positive effect on cybersecurity awareness (p value ≤0.001, β = 0.192). This shows that having a thorough understanding of software security can raise cybersecurity awareness up to 19.2%. E-mail security variable (X2) has a significant and positive effect on cybersecurityawareness (p -value ≤0.000). This shows that having a thorough understanding of email security can raise cybersecurity awareness up to 31.3%. Software security (X1) and e-mail security (X2) variables simultaneously have a significant effect on cybersecurity awareness (p -value ≤0.000) with a correlation coefficient of 12.1% (R2 = 0.121). This shows that the independent variable used can explain the level of cybersecurity awareness up to 12.1%. Research results show that students are aware of software or application updates. Furthermore, students' awareness of email security is also good. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic has had a significant impact on public life and health worldwide, putting the world's healthcare systems at risk. The first step in stopping this outbreak is to detect the infection in its early stages, which will relieve the risk, control the outbreak's spread, and restore full functionality to the world's healthcare systems. Currently, PCR is the most prevalent diagnosis tool for COVID-19. However, chest X-ray images may play an essential role in detecting this disease, as they are successful for many other viral pneumonia diseases. Unfortunately, there are common features between COVID-19 and other viral pneumonia, and hence manual differentiation between them seems to be a critical problem and needs the aid of artificial intelligence. This research employs deep- and transfer-learning techniques to develop accurate, general, and robust models for detecting COVID-19. The developed models utilize either convolutional neural networks or transfer-learning models or hybridize them with powerful machine-learning techniques to exploit their full potential. For experimentation, we applied the proposed models to two data sets: the COVID-19 Radiography Database from Kaggle and a local data set from Asir Hospital, Abha, Saudi Arabia. The proposed models achieved promising results in detecting COVID-19 cases and discriminating them from normal and other viral pneumonia with excellent accuracy. The hybrid models extracted features from the flatten layer or the first hidden layer of the neural network and then fed these features into a classification algorithm. This approach enhanced the results further to full accuracy for binary COVID-19 classification and 97.8% for multiclass classification. [ABSTRACT FROM AUTHOR]

Transplanting horseshoe kidneys is challenging and has higher complication rates due to the unusual anatomy of the vascular and urinary collecting systems. Most centers avoid using these kidneys for transplantation. However, if chosen carefully, these organs can be used successfully to reduce organ shortage. In this paper, we will describe the technique of procurement of horseshoe kidneys from cadaveric donors, back table preparation, and its successful implantation in a recipient. With good planning and skillful surgical techniques, horseshoe kidneys can be successfully transplanted in suitable recipients. If properly selected, these kidneys can be used to reduce the organ scarcity and diminish waitlist morbidity and mortality. [ABSTRACT FROM AUTHOR]

Summary: This article proposes a mixed integer linear programming (MILP)‐based algorithm to estimate faults locations, types, and fault current magnitudes in unbalanced three‐phase distribution networks. The proposed method requires voltage phasors prior to and during fault conditions. The measurements are collected by microPMUs at the end of the branches along with the bus impedance matrix. To assess the proposed technique's performance in fault location and current identification, different types of faults scenarios are considered. Balanced and unbalanced faults are examined on the IEEE 37‐bus, the IEEE 123‐bus, and 134‐node real‐life feeders. Efficiency of the proposed method is investigated on ungrounded systems, reduced microPMU number, different fault resistances, inaccurate bus impedance matrix, distributed generation penetration, and noisy measurement data. High accuracy rate is achieved by the proposed method in identifying fault locations, types, and current magnitudes. [ABSTRACT FROM AUTHOR]

Solar panels around the globe are primarily designed as a plug‐and‐play solution and the end users are not allowed to repair the panel in case of damage. Natural loadings such wind, snow, sand and hail can lead to irreparable damage to the solar panels and the easiest solution to fix the damaged solar panel is to replace it. This design philosophy leads to a huge quantity of electronic waste as it completely ignores the repairability of the solar panels. In this regard, the presented research work details the development and testing of modular solar panel with performance similar to the traditional design. The modular design was tested for power transfer, re‐connection upon impact and the ability to replace the selected parts in case of permanent damage without the need of replacing the entire solar panel. This experimental research work delivers a modular solar panel design that has ease of repairability in case of damage. Furthermore, a detailed economic analysis has been provided for several real‐world scenarios that indicate its suitability over existing commercially available solutions. [ABSTRACT FROM AUTHOR]

Objective: Vaping is advertised as a method to mitigate weight gain after smoking cessation; however, while there is an established inverse association between conventional tobacco use and body mass index (BMI), there is little research on the relationship between e‐cigarettes and BMI. This research tested whether e‐cigarette use was associated with BMI. Methods: A secondary data analysis of 207,117 electronic medical records from the UAB was conducted. Patient data from 1 September 2017 through 1 June 2018 were extracted. To be included in the analysis, a patient's record had to include measures of e‐cigarette use and key sociodemographic information. Ordinary least squares regression was used to test the association between e‐cigarette use and BMI, controlling for covariates; unconditional quantile regression was used to determine whether the association varied by BMI quantile. For comparison with tobacco smoking, the association between current tobacco smoking and BMI was estimated in a sample from the same population. Results: Respondents in the sample had an average BMI of 30.8 and average age of 50.0 years when BMI was measured. The sample was 51% female, 49.7% white, 46.7% black, and 1.0% Hispanic; 16.4% of the sample had less than a college education and approximately 5% reported currently using e‐cigarettes. Individuals who reported using e‐cigarettes had, on average, a lower BMI compared to those who did not report currently using e‐cigarettes; results indicated that this association did not significantly vary by BMI quantile. Individuals who reported being current smokers had a lower BMI, on average. Conclusion: These findings suggest that using e‐cigarettes is associated with a lower BMI in a population of individuals seeking health care, consistent with the association between conventional tobacco use and BMI. This study is a springboard for future research investigating the associations between e‐cigarette use, BMI, and risk of obesity in the general population. [ABSTRACT FROM AUTHOR]

Objective: Due to the possibility of serious adverse events (AE), patients are commonly admitted to hospital for 3‐5 days for ketogenic diet (KD) initiation. This study examined the incidence of potential AE during admission for KD initiation to investigate the possibility of safely initiating a KD at home. Methods: Children with drug‐resistant epilepsy (DRE) who were admitted to hospital for 5 days for KD initiation were retrospectively studied. Results: A total of 66 children (59% female) were analyzed. The mean age at the initiation of the KD was 48.0 ± 38.4 months, and the mean weight was 14.6 ± 6.3 kg. The median number of anticonvulsant medications used at the time of KD initiation was 3. The etiology of the DRE was structural in 4.5%, hypoxic ischemic encephalopathy in 10.6%, genetic/metabolic in 31.8%, acquired in 10.6%, and unknown in 42.2%. The potential AE occurred in 28.7% of patients, including hypoglycemia (20%), hypoactivity (6.1%), somnolence (3%), and vomiting (7.6%). A univariate analysis of the clinical characteristics of the AE and no AE groups showed a statistically significant difference in weight (P = 0.003) and age (P = 0.033). The concurrent use of topiramate was found to have a near‐significant association (P = 0.097) between the groups. The groups' urine ketone levels on all 5 days were compared, and a statistically significant difference was found on day 3 (P = 0.026). A statistically significant difference in the serum bicarbonate levels (P = 0.038) was found between the patients taking topiramate and those not taking it. Significance: The incidence of AE during admission for KD initiation was found to be low. The AE either required no intervention or were easily managed with simple interventions. Thus, in carefully selected patients, it may be possible to initiate a KD at home if the parents are adequately prepared and monitored. [ABSTRACT FROM AUTHOR]

Key Clinical Message: This case is the first published associated liver partition and portal vein ligation for staged hepatectomy procedure done successfully in Saudi Arabia, with excellent hypertrophic response to the liver remnant. This is a milestone in liver resection techniques in the country and the region. [ABSTRACT FROM AUTHOR]

Background: To date, there has been no study identified that assessed peri‐implant parameters and local levels of proinflammatory cytokines between waterpipe smokers (WS) and electronic cigarette users (VS). To evaluate the true effect of the risk indicator (WS and VS), a positive control (cigarette smokers [CS]) was added in the study design. Purpose: To compare clinical and radiographic peri‐implant parameters and proinflammatory cytokine profile in the peri‐implant sulcular fluid (PISF) among CS, WS, VS, and nonsmokers (NS). Materials and Methods: Forty CS, WS, VS, and NS were included. Details regarding demographics, duration of implants, and habits were recorded. Clinical examination for periodontal and peri‐implant plaque index (PI), bleeding on probing (BOP), and probing depth (PD ≥ 4 mm) were assessed. Radiographic bone loss (RBL) was assessed using digital periapical radiographs and viewed on a calibrated computer screen using an image analyzer. Levels of tumor necrosis factor‐alpha (TNF‐α), interleukin (IL)‐6, and IL‐1β in PISF were evaluated using enzyme‐linked immunosorbent assay. Results: Mean peri‐implant PI (P < .05), PD ≥ 4 mm (P < .05), and total RBL (P < .01) was significantly higher among CS, WS, and VS compared with NS. Statistical differences in BOP were observed in NS (P < .01) compared to CS, WS, and VS. CS and WS showed significantly higher PD ≥ 4 mm and RBL compared with VS (P < .05). Levels of TNF‐α, IL‐6, and IL‐1β were significantly higher in CS, WS, and VS compared to NS. There were no statistical differences in the mean levels of all proinflammatory cytokines among individuals in CS and WS. Conclusion: Tobacco smoking is associated with poor peri‐implant health. The effect of waterpipe smoking was of largely the same extent as that of cigarette smoking. Higher levels of inflammatory cytokines in tobacco smokers may propose increased peri‐implant inflammatory process which could play a principal role in the progression of peri‐implant tissue damage. [ABSTRACT FROM AUTHOR]

Objectives. To identify prevalence and risk factors of depression among caregivers of Alzheimer’ disease (AD) patients. Methods. In a cross-sectional study, 110 caregivers of AD patients participated in this study (51 males and 59 females). Patients data were obtained from patients’ records at Aseer Central Hospital. Depression among caregivers was assessed by using the Hamilton Rating Scale for Depression. Results. The age of caregivers ranged from 17 to 85 years (Mean±SD: 41.1±14.0 years). Prevalence of depression among caregivers was 70%. Caregivers were mainly sons/daughters (69.1%) or spouses (11.8%). A total of 33 caregivers (30%) had mild depression while 44 (40%) had moderate depression. Prevalence of depression was significantly higher among caregivers of AD patients who were exposed to repeated falling down (p=0.003), but did not differ significantly among caregivers who were exposed to repeated pneumonia or getting lost. Caregivers’ scores of depression positively correlated with duration of caregivers’ daily stay with AD patients (r=0.272, p=0.004), but did not correlate significantly with either caregivers’ age or patients’ age. Moreover, caregivers’ depression did not differ significantly according to their marital status, educational status, employment status, or monthly income. Conclusions. Prevalence of depression among AD caregiver is high. Risk factors for depression include patients’ exposure to repeated falls and prolonged stay with patients. Therefore, psychiatric care should be provided to caregivers, home safety should be maintained to avoid falls, and several persons should interchangeably provide care to AD patients. [ABSTRACT FROM AUTHOR]

Summary: In this paper, we propose a fast algorithm for computing the spectral radii of symmetric nonnegative tensors. In particular, by this proposed algorithm, we are able to obtain the spectral radii of weakly reducible symmetric nonnegative tensors without requiring the partition of the tensors. As we know, it is very costly to determine the partition for large‐sized weakly reducible tensors. Numerical results are reported to show that the proposed algorithm is efficient and also able to compute the spectral radii of large‐sized tensors. As an application, we present an algorithm for testing the positive definiteness of Z‐tensors. By this algorithm, it is guaranteed to determine the positive definiteness for any Z‐tensor. [ABSTRACT FROM AUTHOR]

Abstract: Both the recent advances in mobile technologies and the high penetration rate of mobile communication services have had a profound impact on our daily lives, and are beginning to offer interesting and advantageous new services. In particular, the mobile transaction (mtransaction) system has emerged, enabling users to pay for physical and digital goods and services using their mobile devices whenever they want and wherever they are. It is anticipated that M‐transaction will enjoy a bright future. However, apparently there is still a lack of acceptance of mobile transaction amongst users. This paper empirically investigates what are the factors that make the mobile subscribers reluctant, and which factors that make them keen to accept m‐transaction. This study applies a modified model of the Unified Theory of Acceptance and use of Technology (UTAUT), a robust well‐known model, as an approach to collect and analyse the data and, therefore, to develop a categorization of the important factors that play a role in accepting and using M‐transaction. Following a qualitative method, semi‐structured interviews were conducted with Saudi residents to elicit their opinions and concerns about using m‐transaction in Saudi Arabia. The findings of this study show that the factors that have the most significant influence on the acceptance and use of m‐transaction in Saudi Arabia are: usability, usefulness, telecommunications infrastructure, security, hacking and fraud, availability, trust, payment gateway, awareness, cost and promotion, privacy, cyber‐law, the postal services, government e‐readiness, Arabic language support. [ABSTRACT FROM AUTHOR]

Background. Primary hyperparathyroidism is rare in pregnancy. An association between primary hyperparathyroidism and preeclampsia has been reported in few cases worldwide. Case. A 28-year-old woman (gravida 2, para 0, and abortus 1) in her 27th week of gestation was hospitalized due to a high reading of blood pressure (194/115 mmHg) that was not accompanied by any symptoms or signs of preeclampsia. Incidentally, she was found to have a high adjusted calcium and serum parathyroid hormone (PTH) level during admission. Ultrasonographic examination of the neck revealed the presence of parathyroid adenoma. She was scheduled for surgical excision after receiving an intravenous hydration. Fetal ultrasonography revealed a growth restricted fetus with normal biophysical profile. On the sixth day of hospitalization, the patient complained of headache and epigastric pain, with elevated BP and proteinuria. The fetal nonstress test was “nonreassuring.” Subsequently, she had an emergency cesarean delivery and surgical removal of the adenoma. The mother and her newborn were then transferred to intensive care, where their clinical course was unremarkable. The mother was discharged after 3 days, while the neonate stayed for close observation for 60 days. Conclusion. Early recognition of primary hyperparathyroidism among women with preeclampsia is important to prevent maternal and fetal morbidity and mortality. [ABSTRACT FROM AUTHOR]