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The aim of this study is to examine how different factors (multiple stigmatization, perceived social status, and workers' sex) as well as their interactions are associated with the dehumanization of workers. In the preliminary study (N = 991), we selected 16 occupations with different types of stigmatization and perceived status relevant to the Russian socio‐cultural context. In two experimental studies (N1 = 1060, N2 = 1081), we demonstrated that multiple stigmatization increases metaphor‐based and attribute‐based animalistic but not mechanistic dehumanization: low‐status workers were more animalistically dehumanized than high‐status workers; the high status decreased the metaphor‐based animalistic dehumanization of occupations with multiple stigmatization, and the attribute‐based animalistic and mechanistic dehumanization of workers regardless of their stigmatization; and male workers were more mechanistically dehumanized than female ones but there were no differences in animalistic dehumanization. The results obtained are discussed in the context of understanding the specificity of workers' dehumanization and the possible consequences of this dehumanization. [ABSTRACT FROM AUTHOR]