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ABSTRACT We present the development of a method for the determination of methylene bridge crosslinking in 13C-labeled chloromethylated polystyrene-divinylbenzene resins. Our system uses a new room temperature reduction of the chloromethyl groups that circumvents the possible challenges associated with additional crosslinking. We demonstrate how the reduction of the chloromethyl groups allowed for the determination of methylene bridging, derived from the methylenebis(ethenylbenzene) crosslinker, based on the integration of the methylene signal in the 13C NMR spectra. Utilizing this method, the total crosslinking within the chloromethylated resin generated at 35 °C was determined to be upward of 10 wt %, which increased from 6 wt % in the unfunctionalized resin. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2016, 54, 1955-1960 [ABSTRACT FROM AUTHOR]

Examines the pharmacological action of disulfiram, a sulphydryl group reagent, in the treatment of alcoholism. Interests in the metabolism of disulfiram; Inhibition of enzymes involved in ethanol catabolism; Details on the principal toxic clinical effects of disulfiram administration.

The Cu-catalyzed radical addition between α-bromocarbonyls and in situ-generated nitroso compounds gives a wide range of α-amino carbonyls under mild reaction conditions. [ABSTRACT FROM AUTHOR]

Review: 41 refs. [ABSTRACT FROM AUTHOR]