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Summary: The current study aimed to evaluate the viability of microencapsulated Lactobacillus casei to simulated gastrointestinal digestion and storage after optimisation of the psyllium (PG) and gelatin (GE) gum mixtures (2:1, 1:2, 1:1, 0:1 and 1:0) enriched with selenium (Se). Our results exhibited that the size of spherical particles ranged from 643.9 ± 1.77 to 1151.5 ± 3.38 μm. The ratio of 2PG:1GE showed the highest encapsulation efficiency (89.8% ± 0.77) and selenium entrapment (6.92 ± 0.16 ppm). Fourier‐transform infrared spectroscopy (FTIR) data exposed new spectra in the 2PG:1GE samples. Microencapsulated L. casei with 2PG:1GE were resistant to simulated gastric conditions (pH 1.8, 1 h) and bile solution (pH 7.4, 120 min), and during the storage period at room temperature, leading to significant (p < 0.05) higher survival in comparison with free cells. In short, this study optimised the concentrations of PG and GE to entrap Se and carry L. casei efficiently, providing significant protection during exposure to various aggressive conditions. [ABSTRACT FROM AUTHOR]

Conventional static random‐access memory (SRAM) suffers from high leakage power in advanced complementary metal‐oxide‐semiconductor nodes. Meanwhile, gain‐cell embedded dynamic random‐access memory (GC‐eDRAM) is an area‐efficient alternative to SRAM, although it requires periodic refresh cycles. In this regard, this study proposes a fin field‐effect transistor (FinFET)‐based 5T GC‐eDRAM bitcell that addresses the leakage power issue of SRAM while avoiding the bandwidth‐consuming refreshes of GC‐eDRAM. Furthermore, for the feasibility of scaling down transistors, the gain‐cell design is based on the FinFET, which overcomes short‐channel problems. The proposed 5T bitcell provides additional internal feedback relative to the 4T all‐nMOS fully depleted‐silicon on insulator (FD‐SOI) gain cell to ensure the static retention of both "1" and "0" data. The 2‐kB array was simulated by employing a 7‐nm FinFET predictive technology model (PTM) using HSPICE. The simulation results show that the proposed 5T bitcell (at 0.7 V) enables over 13× smaller data retention power and 10× area reduction compared to the 4T all‐nMOS GC‐eDRAM cell in a 28‐nm FD‐SOI technology. [ABSTRACT FROM AUTHOR]

In this study, the emulsifying and foaming properties of a novel exudate gum from Dorema ammoniacum (AMG) were assessed in comparison with the well‐known gum Arabic from Acacia tree (GAC). The sunflower oil‐based emulsion (10% v/v) containing various concentrations (5%–15% w/v) of AMG and GAC was prepared. At all concentrations, AMG showed higher surface and interface activity than GAC. Increasing in AMG and GAC concentrations caused to increase and decrease in Z average, respectively. Overall, the GAC‐stabilized emulsion showed lower Z average and PDI value than the AMG‐stabilized emulsion during storage time. The sample containing AMG showed higher emulsion capacity and lower emulsion stability in comparison with the one containing GAC at all concentrations. The storage stability decreased and increased with increasing in AMG and GAC concentrations, respectively. After two‐week storage, the emulsions containing 10 and 15% AMG showed higher phase separation than those containing GAC; however, this was opposite about sample containing 5% AMG. At thermal, centrifuge, and freezing conditions, the emulsion containing 5% AMG indicated significantly higher stability than GAC samples; however, at higher concentration, opposite effect could be observed. The foaming capacity of the samples containing AMG increased from 81% to 93% by increasing gum concentration from 5% to 15%. The solutions containing AMG showed higher foam capacity than control samples (without gum) and those containing GAC at all concentrations. Increasing in AMG and GAC concentrations slightly improved foam stability, and the highest value (92%) belonged to 15% AMG solution. [ABSTRACT FROM AUTHOR]

This study presents a new energy‐efficient design for static random access memory (SRAM) using a low‐power input data encoding and output data decoding stages. A data bit reordering algorithm is applied to the input data to increase the number of 0s that are going to be written into the SRAM array. Using SRAM cells which are more energy‐efficient in writing a '0' than a '1' benefits from this, resulting in a reduction in the total power and energy consumptions of the whole memory. The input data encoding is performed using a simple circuit, which is built of multiplexers and inverters. After the read operation, data will be returned back to its initial form using a low‐power data decoding circuit. Simulation results in an industrial and a predictive CMOS technology show that the proposed design for SRAM reduces the energy consumption of read and write operations considerably for some standard test images as input data to the memory. For instance, in writing pixels of Lenna test image into this SRAM and reading them back, 15 and 20% savings are observed for the energy consumption of write and read operations, respectively, compared with the normal write and read operations in standard SRAMs. [ABSTRACT FROM AUTHOR]

Purpose: Noninvasive imaging techniques that quantify renal tissue composition are needed to more accurately ascertain prognosis and monitor disease progression in polycystic kidney disease (PKD). Given the success of magnetization transfer (MT) imaging to characterize various tissue remodeling pathologies, it was tested on a murine model of autosomal dominant PKD. Methods: C57Bl/6 Pkd1 R3277C mice at 9, 12, and 15 months were imaged with a 16.4T MR imaging system. Images were acquired without and with RF saturation in order to calculate MT ratio (MTR) maps. Following imaging, the mice were euthanized and kidney sections were analyzed for cystic and fibrotic indices, which were compared with statistical parameters of the MTR maps. Results: The MTR-derived mean, median, 25th percentile, skewness, and kurtosis were all closely related to indices of renal pathology, including kidney weight/body weight, cystic index, and percent of remaining parenchyma. The correlation between MTR and histology-derived cystic and fibrotic changes was R²=0.84 and R²=0.70, respectively. Conclusion: MT imaging provides a new, noninvasive means of measuring tissue remodeling PKD changes and may be better suited for characterizing renal impairment compared with conventional MR techniques. [ABSTRACT FROM AUTHOR]

In this paper, a SRAM cell structure which uses pMOS access transistors and predischarged bitlines is presented. By using the strained pMOS transistor technology, the degradation of the read static noise margin (SNM) at high supply voltages due to the aging, especially in the presence of symmetric stress, is suppressed. In contrast to conventional cell, the write margin of the proposed cell does not degrade considerably at low supply voltages. To assess the efficacy, the proposed cell is compared with conventional cell for two cases of unstrained and strained pMOS. A comparative study is performed using mixed mode device/circuit simulations for a gate length of 22 nm. The results show that the read SNM degradation due to the symmetric aging at the supply voltage of 1V is about 6% after three years for the proposed strained structure, while degradations are 14%, 12%, and 11% for the unstrained proposed structure, unstrained, and strained conventional structures, respectively. In addition, the proposed cell has both read and write cell sigma yields higher than six for supply voltages ranging from 1V down to 0.5V while the other structures have read or write yields less than six at the minimum supply voltage. Through some work function tuning, the cell sigma yields of the other structures reach above six for both read and write while being still lower than those of the proposed structure. [ABSTRACT FROM AUTHOR]