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Scintillators are widely utilized as X‐ray imaging detectors. Pixelated scintillator films with optical‐waveguide‐effect are preferred to realize high‐resolution X‐ray imaging. However, it remains a great challenge to rapidly fabricate high‐resolution pixelated scintillator film. Herein, a new strategy is developed to solve the problem by embedding metal halide scintillators into an anodic aluminum oxide (AAO) via a facile hot‐pressing method. Cs3Cu2I5 is selected as the prototype to fabricate pixelated scintillator films with targeted thickness, denoted as Cs3Cu2I5−AAO. The light confinement effect provided by AAO is validated by finite‐difference time‐domain simulations. In particular, the as‐prepared Cs3Cu2I5−AAO film demonstrates higher spatial resolution (10.4 lp mm−1 at modulation transfer function = 0.2), higher UV and X‐ray imaging performances compared to the homogeneous counterpart and commercialized terbium‐doped gadolinium oxysulfide. These results can inspire further research on the design of nanostructured metal halide perovskites for high‐resolution X‐ray imaging. [ABSTRACT FROM AUTHOR]

This study evaluated the interaction of Chrysanthemum indicum (CI) flavonoids (luteolin, acacetin, and buddleoside) with α‐amylase. Surface plasmon resonance (SPR) assay showed their equilibrium dissociation constants (KD) are 1.9695 ± 0.12, 2.9240 ± 0.20, and 3.2966 ± 0.08 mM at pH 6.0, respectively. Furthermore, their binding affinities were influenced by KCl, MgCl2, and CaCl2. Enzymatic kinetic studies revealed that three flavonoids exhibited noncompetitive α‐amylase inhibitory activity. The inhibitory sequence is luteolin > acacetin > buddleoside, which was in accordance with the results of binding affinity from SPR. 1,1‐diphenyl‐2‐picryl hydrazyl radical assay demonstrated that antioxidant activities of three flavonoids were inhibited significantly with α‐amylase. Meanwhile, the study reveals that hydroxyl on C′‐4, C′‐5, and C‐7 of flavonoids play an important role on the interaction of three flavonoids with α‐amylase. Also, SPR could be used as sensor for rapid screening inhibitors of α‐amylase and provide useful information for the application of C. indicum flavonoids in food and pharmaceutical area. [ABSTRACT FROM AUTHOR]

Summary: In this work, the effects of three Citrus flavonoids (naringin, neohesperidin and hesperidin) on α‐amylase catalysed starch digestion were investigated. An inhibitory kinetics experiment demonstrated that they noncompetitively inhibit the activity of α‐amylase with Ki values of, respectively, 25.21 μ m, 40.26 μ m, 40.69 μ m. Surface plasmon resonance assay showed three Citrus flavonoids can bind with starch with KD values of, respectively, 3.98 ± 0.20 m m, 4.92 ± 0.15 m m and 5.07 ± 0.17 m m. Scanning electron microscopy indicated they can delay the retrogradation of starch. The results of 1, 1‐diphenyl‐2‐picryl hydrazyl radical assay indicate that the antioxidant activities of three Citrus flavonoids are significantly decreased by interacting with starch. These results illustrated three Citrus flavonoids that retard the digestion of starch not only through interaction with α‐amylase, but also through interaction with starch. [ABSTRACT FROM AUTHOR]

The cover image is based on the ORIGINAL RESEARCH I An assessment of the interaction for three i Chrysanthemum indicum I flavonoids and -amylase by surface plasmon resonance i by Pao Li et al., https://doi.org/10.1002/fsn3.1349. Cover Credit: Cover image © Pao Li and Xia Liu Images. [Extracted from the article]