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Aim Methods Results Conclusion Low‐carbohydrate (LC) diets have gained popularity. We compared glycaemic and metabolic parameters following an LC versus a Mediterranean (MED) diet in adolescents and youths with type 1 diabetes.In a six‐month, open‐label, randomised trial, 40 individuals were assigned to either diet. Glycaemic outcomes, based on continuous glucose monitoring, included per cent time of blood glucose in the range [3.9–10.0 mmol/L (70–180 mg/dL)] and haemoglobin A1c (HbA1c).Twenty‐eight (70%) were females. The median age was 18 years. After 6 months, the median time in range increased from 47% to 58% in the LC and from 52% to 64% in the MED diet group (p = 0.98). The delta values for the time in range were 16% and 7% for the respective groups (p = 0.09). The percentage of time >13.9 mmol/L (>250 mg/dL) improved more in the LC diet than in the MED diet group: −10% vs. −2% (p = 0.005). The percentage of time <3.0 mmol/L (<54 mg/dL) was comparable. The delta HbA1c improved in both groups: −0.7% vs. −0.1% (p = 0.02). Changes in BMI Z‐score and lipid levels were similar.Both diets improved glycaemic outcomes in adolescents and youths with type 1 diabetes, without increasing hypoglycaemia or cardiovascular risk factors, indicating comparable safety and efficacy. [ABSTRACT FROM AUTHOR]

A healthy four-year-old boy presented with new haemorrhagic skin lesions on his thighs and left flank (upper left image). Several hours following treatment initiation, the skin lesion progression ceased, and laboratory tests improved. Laboratory investigations showed a normal full blood count, C-reactive protein (CRP) was 27 mg/l (normal <0-5), prothrombin time (PT) was 57% (normal 75-120%) and activated partial thromboplastin time (APTT) was normal. [Extracted from the article]