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Blood gas analyses have previously been performed for giraffe under anesthesia and with physical restraint in a chute; however, reference values for giraffe that are trained to participate in venipuncture without chemical or physical restraint have not previously been described. Using a point‐of‐care blood gas and lactate analyzer and 20 giraffe trained for voluntary phlebotomy, values were determined for venous blood gasses and plasma lactate concentration. Ninety‐five percent confidence in the mean values for venous pH (7.34–7.46), partial pressure of carbon dioxide (PCO2; 28.5–37.8 mmHg), partial pressure of oxygen (PO2; 56–102 mmHg), bicarbonate (HCO3−; 18.9–21.0 mmol/L), base excess (BE; −6.0 to −3.6 mmol/L), total carbon dioxide (TCO2; 19.9–22.0 mmol/L), and lactate (0.32–0.56 mmol/L) were calculated. This is the first report on venous blood gas analysis values for giraffe without chemical or physical restraint. These data will provide a reference for clinical interpretation of venous blood gas and lactate values in giraffe and demonstrate some of the potential diagnostic benefits to training giraffe and other zoo species for voluntary medical procedures. Key Points/Highlights: We established reference values for venous blood gas and lactate concentrations in conscious giraffes trained for voluntary phlebotomy.Using a point‐of‐care blood gas analyzer to obtain rapid and accurate assessments of cardiopulmonary and metabolic physiology in giraffes may aid in clinical decision making.A comparison of blood gas values between giraffes housed at different altitudes revealed significant differences in base excess and serum bicarbonate levels.Voluntary training programs contribute to the advancement of medical care and welfare of giraffe. [ABSTRACT FROM AUTHOR]

Prisoner incompatibility is a challenge for correctional officers (COs), as incompatible people in prison are more likely to engage in negative interactions, participate in altercations, cause harm to each other and create tension on a unit. Through in‐depth semi‐structured interviews with 28 COs employed in Atlantic Canada, we explore how incompatibility among incarcerated people shapes how incarcerated people are managed and perceived by COs. Engaging the prison design literature, we further examine the kinds of spatial designs and protocols that contribute to, or mitigate, incompatibility. We find that COs describe a complex prison hierarchy that, while being laced with challenges beyond the control of COs, could nevertheless be effectively mitigated through architectural transformation or policy reforms. We highlight the need to consider how prison culture informs and is interpolated through spatial configurations of correctional institutions and how these social and spatial dynamics shape interactions between prisoners. [ABSTRACT FROM AUTHOR]

PF614, a trypsin‐activated abuse protection oxycodone prodrug designed to reduce recreational drug abuse, was compared to OxyContin for safety and pharmacokinetics (PKs) of plasma oxycodone following oral administration. This study was a two‐part design including a multi‐ascending dose (part A) and a bioequivalence (BE) study (part B) in healthy volunteers. In part A, 24 subjects were randomized 3:1 to receive PF614 (50, 100, or 200 mg, n = 6/cohort) or OxyContin (20, 40, or 80 mg; n = 2/cohort) in ascending cohorts, delivered every 12 h for a total of nine doses. In part B, 60 subjects randomized in a four‐way crossover to evaluate BE, received PF614 100 mg and OxyContin 40 mg in fasted and fed (high‐fat diet) states. All subjects were naltrexone blocked prior to first study drug administration to protect against opioid‐related adverse effects; repeat doses were provided on days 1–5. In part A, PF614 was well‐tolerated following twice daily doses of up to 200 mg for 5 days. Plasma oxycodone maximal plasma concentration and area under the concentration time curve increased linearly with increasing doses. Part B showed that plasma oxycodone BE was achieved following 100 mg PF614 or 40 mg OxyContin under both fasted and fed conditions. Additionally, PF614 provided similar oxycodone exposures following both fasted and fed states. This study confirms findings from our single‐ascending dose study, showing that PF614 100 mg releases oxycodone with a PK profile comparable to 40 mg OxyContin under both fasted and fed conditions and with a similar safety profile under naltrexone‐blocked conditions. [ABSTRACT FROM AUTHOR]

Objective: Anticipated regret has been found to predict vaccination intentions and behaviours. We examined whether anticipated relief also predicts seasonal influenza vaccination intentions and behaviour. Given claims about differences in their antecedents and function, we distinguished between counterfactual relief (relief that a worse outcome did not obtain) and temporal relief (relief that an unpleasant experience is over). Design: Cross‐sectional. Methods: Unvaccinated participants (N = 295) were recruited online in November 2020. Participants completed measures of anticipated regret, anticipated counterfactual relief, and anticipated temporal relief and measures of theory of planned behaviour constructs (attitudes, norms, perceived control, and intentions). One month later, the same participants were re‐surveyed and asked to report their vaccination status. Results: Although all anticipated emotion measures were associated with intentions and behaviour, only anticipated counterfactual relief and regret independently predicted vaccination intentions in regression analyses. Mediation analysis showed both anticipated counterfactual relief and regret were indirectly, via intentions, associated with behaviour. Conclusions: Results suggest that, regardless of valence, counterfactual emotions predict vaccination intention and, indirectly, behaviour. Furthermore, participants may differ in their sensitivity to the anticipation of positive versus negative counterfactual emotions. These findings may permit more precise targeting of interventions to increase vaccine uptake. [ABSTRACT FROM AUTHOR]

Intravenous remdesivir (RDV) is US Food and Drug Administration–approved for hospitalized and nonhospitalized individuals with coronavirus disease 2019. RDV undergoes intracellular metabolic activation to form the active triphosphate, GS‐443902, and other metabolites. Alternative administration routes, including localized pulmonary delivery, can lower systemic exposure and maximize exposure at the site of action. This study evaluated the pharmacokinetics (PK) and safety of inhaled RDV in healthy adults. This phase Ia, randomized, placebo‐controlled study evaluated inhaled RDV in healthy participants randomized 4:1 to receive RDV or placebo as single doses (4 cohorts) or multiple once‐daily doses (3 cohorts). Doses in cohorts 1–6 were administered as an aerosolized solution for inhalation through a sealed facemask; doses in cohort 7 were administered as an aerosolized solution for inhalation through a mouthpiece. Safety was assessed throughout the study. Seventy‐two participants were enrolled (inhaled RDV, n = 58 and placebo, n = 14). Following single RDV doses, RDV, GS‐704277, and GS‐441524 plasma PK parameters indicated dose‐proportional increases in area under the concentration‐time curve (AUC) extrapolated to infinite time, AUC from time zero to last quantifiable concentration, and maximum observed concentration. Analyte plasma concentrations after multiple RDV doses were consistent with those for single‐dose RDV. Analyte plasma exposures were lower when RDV was administered with a mouthpiece versus a sealed facemask. The most common adverse events included nausea, dizziness, and cough. Single‐ and multiple‐dose inhaled RDV exhibited linear and dose‐proportional plasma PK. Administration of RDV via inhalation was generally safe and well‐tolerated. [ABSTRACT FROM AUTHOR]

Research indicates that, relative to the general public and most other types of public safety personnel, correctional workers are more likely to engage in suicide ideation, planning, and attempts. Yet, less is known about lived experiences towards, of, and beyond suicidality among correctional staff. To contribute to this gap in knowledge, the current study draws on qualitative, open‐ended survey response data (n = 94) to explore how Canadian provincial correctional workers navigate experiences of suicide, with a focus on the individual, personal, and social factors tied to experiences towards and of suicide thoughts and behaviours. By engaging the seminal works of Foucault, Žižek, and Deleuze and Guattari, we explore respondents' distinct forms of agency when grappling with, challenging, and transcending thoughts around suicide. We then discuss the research implications, with an emphasis on providing correctional workers with confidential, non‐stigmatised well‐being and treatment‐seeking resources and processes, and more health care funding to fully cover timely and sufficient mental health treatment, prevention, and intervention. [ABSTRACT FROM AUTHOR]

Background: Clostridioides difficile infection (CDI) is a form of antibiotic‐associated infectious diarrhoea resulting in significant morbidity and mortality. Community‐acquired disease in low‐risk individuals is increasingly recognised. There are limited New Zealand data published. Aim: To determine the incidence and location of onset of CDI cases in the Manawatu region, and further describe the demographics, risk factors and prevalent C. difficile ribotypes of the population. Methods: We performed an incidence case–control study of CDI in the Manawatu region between September 2018 and September 2019. Cases were matched to controls with a negative test for C. difficile. Demographic and comorbidity data, location of onset, drug exposure, disease recurrence and 30‐day mortality were collected. Ribotype analysis was performed on C. difficile isolates. Results: Thirty‐two specimens tested toxin positive over 12 months, yielding an incidence of 18.3 cases per 100 000 person‐years. Twenty‐five percent of cases had community onset disease. Cases were more likely to have had amoxicillin/clavulanate or ceftriaxone prescribed. Elevated blood white cell count and lower HbA1c were significantly associated with CDI. The dominant ribotype was 014/020. Two cases were RT 023. Conclusion: Our data are similar to previous national data. RT 023 has not been previously reported in New Zealand and has been associated with severe colitis. We demonstrated a significant proportion of community‐acquired cases and the true incidence might be higher. Vigilance for community onset disease is required. These data may allow observation of temporal changes in incidence and infection patterns of CDI in New Zealand. [ABSTRACT FROM AUTHOR]

The MWW test challenges the null hypothesis that two data distributions are the same (Mann & Whitney, 1947), not whether the two distributions have the same median. A bootstrap approach is a superior statistical method for the comparison of non-normal data with differing variances Keywords: bootstrap; cell-to-cell movement; heteroskedastic; Mann-Whitney-Wilcoxon; null hypothesis significance testing; plasmodesmata; statistics EN bootstrap cell-to-cell movement heteroskedastic Mann-Whitney-Wilcoxon null hypothesis significance testing plasmodesmata statistics 23 26 4 03/04/21 20210401 NES 210401 Phytologists have a primary interest in understanding plant growth, development and environmental responses. Bootstrap, cell-to-cell movement, heteroskedastic, plasmodesmata, statistics, Mann-Whitney-Wilcoxon, null hypothesis significance testing. [Extracted from the article]

Objective: To present the results of clinical, surgical, and histopathologic procedures and how these were compared with the initial presumptive clinical diagnosis in a corn snake (Pantherophis guttatus) presenting with subspectacular fluid opacity; and to improve upon currently established surgical enucleation techniques in the snake. Animal studied: An 8‐month‐old corn snake was presented for enlarged globe OD. Procedures: The following diagnostics were performed: systemic and ophthalmic examinations, complete blood count, cytology and culture of subspectacular fluid, and histopathology of enucleated globe and spectacle. Enucleation was performed in a routine fashion with the addition of a porcine small intestinal submucosa bioscaffold graft (SISplus™; Avalon Medical, Stillwater, MN), sutured over the orbit. Results: Systemic examination revealed signs of maxillary stomatitis. Ophthalmic examination revealed semitransparent fluid in the subspectacular space. Complete blood count was unremarkable. Cytology of fluid obtained via subspectacular centesis was acellular, and culture grew Clostridium perfringens, which was consistent with the clinical suspicion of right maxillary stomatitis. Histopathology of the enucleated globe revealed spectaculitis, characterized by regional heterophilic inflammation, and no evidence of lymph dissection in the (peri)ocular tissues. The final diagnosis was a subspectacular abscess. Follow‐up revealed that the SIS graft provided excellent healing and cosmesis of the surgical site. Conclusions: While there are reports of lymphatic fluid dissection between skin layers during ecdysis, which can result in an opaque spectacle, the fluid opacity in this case was attributed to a subspectacular abscess secondary to an ascending oral infection. Addition of biological wound dressing may contribute to positive post‐enucleation outcome in the snake. [ABSTRACT FROM AUTHOR]

Objective: Iridocorneal angle (ICA) narrowing is a known risk factor for primary glaucoma in multiple species, but has not been described in companion rabbits. This study aimed to develop an ICA grading scheme for companion rabbits to enable early glaucoma predisposition diagnosis. Animals studied: Twenty healthy rabbits of varying breeds and ages. Procedures: Rabbits received complete ophthalmic examinations, including gonioscopy, and imaging of the ICA using spectral‐domain optical coherence tomography (SD‐OCT), Scheimpflug imaging (Pentacam® HR), and high‐resolution ultrasound (HRUS). Angle opening distance (AOD) and angle recess area (ARA) of the ICA were measured and assessed for agreement using a Bland‐Altman analysis. A five‐stage gonioscopy grading scheme was created, and Spearman‐rank test assessed for correlation between gonioscopy grades and ICA measurements. Differences among age and sex were analyzed with a nonparametric ANOVA and Wilcoxon rank‐sum test, respectively. Results: Analysis revealed AOD medians of 0.28mm for SD‐OCT [95% CI: 0.24‐0.31], 0.20mm for Pentacam® HR [95% CI: 0.18‐0.21], and 0.25mm for HRUS [95% CI: 0.22‐0.28]. The median ARA was 0.14mm2 for SD‐OCT [95% CI: 0.117‐0.163], 0.09mm2 for Pentacam® HR [95% CI: 0.082‐0.100], and 0.06mm2 for HRUS [95% CI: 0.046‐0.054]. The association between gonioscopy grade and SD‐OCT ARA was significant (P < 0.05), and there was a significant difference (P < 0.001) between imaging modalities for both ARA and AOD. Conclusions: Gonioscopy grade correlated well with SD‐OCT ARA. Therefore, SD‐OCT is recommended as a noncontact method for evaluating companion rabbit ICA. Each imaging device should not be used interchangeably for ICA evaluation. [ABSTRACT FROM AUTHOR]

Animal movement and habitat selection are in part a response to landscape heterogeneity. Many studies of movement and habitat selection necessarily use environmental covariates that are readily available over large‐scales, which are assumed representative of functional habitat features such as resource availability. For widely distributed species, response to such covariates may not be consistent across ecosystems, as response to any specific covariate is driven by its biological relevance within the context of each ecosystem. Thus, the study of any widely distributed species within a limited geographic region may provide inferences that are not widely generalizable. Our goal was to evaluate the response of a marine predator to a suite of environmental covariates across a wide ecological gradient. We identified two behavioral states (resident and transient) in the movements of shortfin mako sharks Isurus oxyrinchus tracked via satellite telemetry in two regions of the western North Atlantic Ocean: the tropical Caribbean/Gulf of Mexico marginal sea (CGM), and the temperate waters of the open western Atlantic Ocean (OWA). We compared patterns of resident behavior between regions, and modeled relationships between oceanographic variables and resident behavior. We tracked 39 sharks during 2013–2015. Resident behavior was associated with shallow, continental shelf and slope waters in both regions. In the OWA resident behavior was associated with low sea surface temperature and high primary productivity, however, sharks exhibited no response to either variable in the CGM. There was a negative relationship between sea‐surface height gradient (a proxy for oceanic fronts) and resident behavior in the OWA, and a positive relationship in the CGM. Our observations likely reflect shark responses to regional variability in factors responsible for the distribution and availability of prey. Our study illustrates the importance of studying widely distributed species in a consistent manner over large spatial scales. [ABSTRACT FROM AUTHOR]

Mesoscale oceanic features such as eddies generate considerable environmental heterogeneity within the pelagic oceans, but their transient nature makes it difficult to identify both their spatial and temporal extent and their effects on the distribution of pelagic fauna. Simplifying these complex features using a biologically meaningful classification system will likely be a useful first step in understanding the extent of their influence in structuring openocean ecosystems. In this study, we present a tool to classify the pelagic environment in the Gulf of Mexico using seasurface height and temperatureatdepth data from the 1/25° GOM HYbrid Coordinate Ocean Model (HYCOM). Three "water types" were identified: Loop Currentorigin water (LCOW), Gulf common water (CW), and mixed (MIX) water, where the latter represents an intermediate state during the degradation of LCOW to CW. The HYCOMderived classifications were validated against in situ CTD data and microbial samples collected through 2015–2016 by the Deep Pelagic Nekton Dynamics of the Gulf of Mexico (DEEPEND) consortium. The validation data comprised classifications derived from both temperaturedepth (TD) and temperaturesalinity (TS) profiles and from microbial community analyses from the surface to mesopelagic depths. The HYCOM classifications produced an overall agreement rate of 77% with the TS/TD classifications, and 79% with the microbial classifications. With applicability across a wide range of spatial and temporal scales, we believe that the system provides a useful, complementary tool for biological oceanographers and resource managers interested in better understanding the effects of major mesoscale features on the pelagic biota. [ABSTRACT FROM AUTHOR]

This qualitative content analysis of 503 anonymous online reviews of 52 Canadian call centres posted on RateMyEmployer.ca explores how forms of resistance, alienation and emotional labour are expressed outside of the workplace. Our study finds that digital publics are producing emotive insurgencies and networks of support within marginalised communities that undermine employers' attempts at deadening the workforce. The reviews exemplify worker awareness of exploitation as some connect these issues to broader socio‐economic factors that are beyond their control. While many offer tactics to challenge and destabilise their working conditions and culture as well as heartfelt and sarcastic warnings of what one might expect if they pursue call centre employment, others use the online space as a means of venting frustrations, eliciting empathies and expressing sentiments of hope(lessness). [ABSTRACT FROM AUTHOR]

In the current study, we explored the prison design and infrastructural changes that Canadian correctional officers consider to be essential in the construction of a new provincial correctional institution intended to replace Her Majesty's Penitentiary (HMP) in the Canadian province of Newfoundland and Labrador. Analyzing 28 semi‐structured interviews conducted with correctional officers employed at HMP, we found the poor working conditions within HMP are, at least in part, related to the physical design of the prison, including inadequate lighting, poor air quality and temperature, high sound levels, and other spatial limitations. Building on the prison design literature, findings suggest that while prison design requires attention to physical security at the forefront, there are ways to improve the space, recognizing how an uncomfortable workplace and living conditions also pose a potential threat to the well‐being and safety of correctional officers and people who are incarcerated. [ABSTRACT FROM AUTHOR]

As in the tropical Atlantic, Acropora populations in the southern Persian/Arabian Gulf plummeted within two decades after having been ecosystem engineers on most wave-exposed reefs since the Pleistocene. Since 1996/1998 live coral cover in the Gulf declined by over 90% in many areas, primarily due to bleaching and diseases caused by rising temperatures. In the formerly dominant table-coral species A. downingi, population dynamics corresponding to disturbance regimes was quantified in three transition matrices (lower disturbance pre-1996; moderate disturbance from 1998 to 2010 and 2013 to 2017, disturbed in 1996/1998, 2010/11/12, 2017). Increased disturbance frequency and severity caused progressive reduction in coral size, cover, and population fecundity. Small size-classes were bolstered more by partial colony mortality than sexual recruitment. Some large corals had a size refuge and resisted die-back but were also lost with increasing disturbance. Matrix and biophysical larval flow models suggested one metapopulation. Southern, Arabian, populations could be connected to northern, Iranian, populations but this connectivity was lost under assumptions of pelagic larval duration at rising temperatures shortened to a third. Then, the metapopulation disintegrated into isolated populations. Connectivity required to avoid extinctions increased exponentially with disturbance frequency and correlation of disturbances across the metapopulation. Populations became unsustainable at eight disturbances in 15 years, when even highest theoretical recruitment no longer compensated mortality. This lethal disturbance frequency was 3-fold that of the moderately disturbed monitoring period and 4-fold of the preceding low-disturbance period--suggesting ongoing shortening of the disturbance-free period. Observed population collapse and environmental changes in the Gulf suggest that A. downingi is heading toward at least functional extinction mainly due to increasingly frequent temperature-induced mortality events, clearly linked to climate change. [ABSTRACT FROM AUTHOR]

Abstract: This qualitative content analysis of 723 anonymous reviews of 60 Canadian food service employers, posted on RateMyEmployer.ca, explores how digital spaces publically circulate precarious workers’ resistances and management of occupational stigma. We introduce to literature on “dirty work” the concept of socioeconomic hygiene, which identifies a particular kind of social and moral order within which the positions of the subordinated are naturalized between the socially and morally “clean” and “unclean.” [ABSTRACT FROM AUTHOR]

In this study, we demonstrate how perturbations to the Florida Current caused by hurricanes are relevant to the spread of invasive lionfish from Florida to the Bahamas. Without such perturbations, this current represents a potential barrier to the transport of planktonic lionfish eggs and larvae across the Straits of Florida. We further show that once lionfish became established in the Bahamas, hurricanes significantly hastened their spread through the island chain. We gain these insights through: (1) an analysis of the direction and velocity of simulated ocean currents during the passage of hurricanes through the Florida Straits and (2) the development of a biophysical model that incorporates the tolerances of lionfish to ocean climate, their reproductive strategy, and duration that the larvae remain viable in the water column. On the basis of this work, we identify 23 occasions between the years 1992 and 2006 in which lionfish were provided the opportunity to breach the Florida Current. We also find that hurricanes during this period increased the rate of spread of lionfish through the Bahamas by more than 45% and magnified its population by at least 15%. Beyond invasive lionfish, we suggest that extreme weather events such as hurricanes likely help to homogenize the gene pool for all Caribbean marine species susceptible to transport. [ABSTRACT FROM AUTHOR]

Drawing on an ethnographic narrative written by one of the authors following his resignation from a hospital private security team in Ottawa, Canada and interview data gleaned from eight security men (all former colleagues), this article explores how hospital private security officers draw on discourses of masculinity to navigate the 'dirty' boundaries of their work, and to preserve their alpha-guard statuses as controlled, autonomous and authoritative subjects. We found that hospital guards manage and deflect taint status by emphasizing their resiliency, emotional detachment and enthusiasm towards morbid, disturbing and dangerous tasks. Guards who seek to challenge these components of the job may be subject to gender harassment and reprisal from other guards, senior security officials and nursing staff. Overall, these narratives call attention to the necessity of hospital training programmes, de-briefing exercises and best-communication practices that promote the physical and emotional well-being of persons who engage in intensive forms of dirty work. [ABSTRACT FROM AUTHOR]

Repeated exposure to psychostimulant drugs can result in behavioral sensitization, an amplified response in locomotor activity and stereotypy, which is used to model aspects of drug addiction. The expression of behavioral sensitization, induced by i.p. injections of nicotine once daily for 5 days, was examined in 450-day-old male rats exposed prenatally on GD 8–20 to one of the following conditions: (1) low nicotine: 2.5 mg/kg/day nicotine [LN]; (2) high nicotine: 5.0 mg/kg/day nicotine [HN]; (3) low nicotine/high cocaine: 2.5 mg/kg/day nicotine plus 40 mg/kg/day cocaine [LN/HC]; (4) high nicotine/low cocaine: 5.0 mg/kg/day nicotine plus 20 mg/kg/day cocaine [HN/LC]; (5) pair-fed controls: food intake yoked to HC dams [PF]; and (6) saline controls: daily injections of 0.9% NaCl solution[SAL]. Initial injection of nicotine did not alter activity or stereotypy in comparison to saline injections, with offspring in all prenatal treatment groups showing a desensitization to nicotine. Five consecutive daily nicotine injections resulted in behavioral sensitization in HN and HN/LC prenatal drug groups. Offspring exhibited an increase in horizontal activity that was evident on day 3, and still present after a 1.0 mg/kg i.p. nicotine challenge 72 hours after the last injection (day 8). SAL offspring exhibited attenuated sensitization. In contrast, nicotine sensitization was not seen in the LN, HC/LN, and the PF offspring; activity remained at the level seen after the initial injection of nicotine. Moreover, nicotine significantly reduced total activity in the LN and PF groups in comparison with their saline-injected counterparts. These data suggest that gestational exposure to high-dose nicotine, either alone or in combination with cocaine, may carry a greater risk than low-dose nicotine exposure of stimulant abuse in later life. [ABSTRACT FROM AUTHOR]

This study is a preliminary assessment of suitable binders and formats of potential formulated diets for hatchery growout of early-stage western spiny lobster, Panulirus cygnus, phyllosomata. Six dry meal (each bound with a different binder) and three gelatinous (all bound using gelatine) diets were tested for stability in water over increasing periods of time (4, 8, and 12 h), and the feeding response to each was observed by video analysis. The gelatinous krill diet appears most suited to the larval feeding biology of P. cygnus phyllosomata as it elicited a heightened feeding response immediately following immersion, was most stable in water up to 4 h, and did not foul the maxillae during ingestion. The dry meal diets were not as stable in water and contributed to excessive fouling of the maxillae during ingestion. Of the dry meal diets, the most suitable was bound with 5% k-carrageenan, presumably because of high moisture content and softer texture. [ABSTRACT FROM AUTHOR]

Objective Design Methods Results Conclusions Anticipated regret has been implicated in health‐related decision‐making. Recent work on influenza vaccination has suggested that anticipated relief, too, may influence individuals' decisions to engage in positive health behaviours. To explore these affective components further and address the generality of possible mechanisms underlying these associations, we examined whether anticipated relief and anticipated regret independently predict testicular self‐examination (TSE) intention and behaviour. Given claims about differences in their nature and function, we distinguished between counterfactual relief (relief that a worse outcome did not obtain) and temporal relief (relief that an unpleasant experience is over).Prospective correlational.At Time 1 (July 2022), 567 cis‐gendered males were asked to complete measures of anticipated regret, anticipated counterfactual and temporal relief, measures of the Theory of Planned Behaviour and measures of anxiety and shame. One month later, the same participants were recontacted and asked about their engagement in TSE in the previous month.Anticipated counterfactual relief and anticipated regret are independent, positive, predictors of intention to engage in TSE and, indirectly, TSE behaviour itself. Interestingly, anticipated temporal relief was negatively associated with intention to engage in TSE and, indirectly, behaviour.Our results suggest that it may be the counterfactual nature of anticipated regret and anticipated relief that underlies their positive association with TSE and other health‐promoting behaviours. Interventions designed to increase engagement in preventive health behaviours, such as TSE, may benefit from the consideration of both positively and negatively valenced counterfactual emotions. [ABSTRACT FROM AUTHOR]