1. Histopathology of congestive nephropathy: a case description and literature review.
- Author
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Husain‐Syed, Faeq, Rangaswami, Janani, Núñez, Julio, Skrzypek, Susanne, Jux, Christian, Gröne, Hermann‐Josef, and Birk, Horst‐Walter
- Subjects
CARDIO-renal syndrome ,ACUTE kidney failure ,LITERATURE reviews ,HEART failure ,CELL differentiation ,KIDNEY diseases ,INTRA-abdominal hypertension - Abstract
Congestive nephropathy is an underappreciated manifestation of cardiorenal syndrome and is characterized by a potentially reversible kidney dysfunction caused by a reduced renal venous outflow secondary to right‐sided heart failure or intra‐abdominal hypertension. To date, the histological diagnostic criteria for congestive nephropathy have not been defined. We herein report a case of acute renal dysfunction following cardiac allograft failure and present a review of the relevant literature to elucidate the current understanding of the disease. Our case demonstrated that congestion‐driven nephropathy may be histopathologically characterized by markedly dilated veins and peritubular capillaries, focally accentuated low‐grade acute tubular damage, small areas of interstitial fibrosis, and tubular atrophy on a background of normal glomeruli and predominantly normal tubular cell differentiation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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