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Introduction: Computable biomedical knowledge artifacts (CBKs) are digital objects conveying biomedical knowledge in machine‐interpretable structures. As more CBKs are produced and their complexity increases, the value obtained from sharing CBKs grows. Mobilizing CBKs and sharing them widely can only be achieved if the CBKs are findable, accessible, interoperable, reusable, and trustable (FAIR+T). To help mobilize CBKs, we describe our efforts to outline metadata categories to make CBKs FAIR+T. Methods: We examined the literature regarding metadata with the potential to make digital artifacts FAIR+T. We also examined metadata available online today for actual CBKs of 12 different types. With iterative refinement, we came to a consensus on key categories of metadata that, when taken together, can make CBKs FAIR+T. We use subject‐predicate‐object triples to more clearly differentiate metadata categories. Results: We defined 13 categories of CBK metadata most relevant to making CBKs FAIR+T. Eleven of these categories (type, domain, purpose, identification, location, CBK‐to‐CBK relationships, technical, authorization and rights management, provenance, evidential basis, and evidence from use metadata) are evident today where CBKs are stored online. Two additional categories (preservation and integrity metadata) were not evident in our examples. We provide a research agenda to guide further study and development of these and other metadata categories. Conclusion: A wide variety of metadata elements in various categories is needed to make CBKs FAIR+T. More work is needed to develop a common framework for CBK metadata that can make CBKs FAIR+T for all stakeholders. [ABSTRACT FROM AUTHOR]

Recent studies conducted on the single releases of multiple software products showed that dependencies concentrate on smaller modules, that is, smaller modules have more dependencies per source line of code. This phenomenon, called the Theory of Relative Dependency, explains why some earlier studies reported that smaller modules were proportionally more defect prone. It is important to test the Theory of Relative Dependency from multiple perspectives so that it can be used as an explanatory argument when garnering organizational support to give a higher quality assurance (QA) priority to smaller modules. In this study, we test the validity of this theory from an evolutionary perspective by examining the consecutive releases of a number of software products. Dependencies do concentrate over smaller modules regardless of the product age. Furthermore, continuous refactoring efforts are associated with increasing concentration of dependencies on smaller modules over product lifetime. Based on the consistent results, software managers and developers should consider giving a higher QA priority to smaller modules over the lifetime of a software product. In the projects where refactoring is adopted continuously, the QA priority on smaller modules should be further increased as the software product ages. Copyright © 2016 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]