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In this study, the PEDOT:PSS conductive polymer material was spin‐coated on the ITO surface to improve the surface roughness of the ITO and reduce the spikes on the ITO surface, so as to avoid the burning spots generated in the green organic light emitting diode (OLED) when the voltage was applied to light it up. The OLED emitting is successfully survived. Deuterium atoms (isotopes of hydrogen) with heavier atomic weights can strengthen C‐D bonds, slow down the kinetic rate for unwarranted chemical reactions, and improve the performance and stability of OLEDs. In this study, deuterated D‐Ir (mppy)3 was employed as the dopant in the emitting layer of green OLED to replace the general Ir (mppy)3 to improve the optoelectronic properties and extend the lifetime of green OLED. At a constant voltage of 4 V, the initial luminance and half lifetime of general Ir (mppy)3 doped and deuterated D‐Ir (mppy)3 doped OLEDs are 188.1 cd/m2, 7.2 h and 438.3 cd/m2, 42.8 h, respectively. It is shown that doping the deuterated D‐Ir (mppy)3 material in the emitting layer has the effect of prolonging the lifetime of OLED. Compared with the general Ir (mppy)3, the lifetime of deuterated D‐Ir (mppy)3 doped OLED achieved an extension by 5.9 times. [ABSTRACT FROM AUTHOR]

Alternative polyadenylation (APA), which is regulated by both cis-elements and trans-factors, plays an important role in posttranscriptional regulation of eukaryotic gene expression. However, comparing to the extensively studied transcription and alternative splicing, the extent of APA divergence during evolution and the relative cis- and trans-contribution remain largely unexplored. To directly address these questions for the first time in mammals, by using deep sequencing-based methods, we measured APA divergence between C57BL/6J and SPRET/EiJ mouse strains as well as allele-specific APA pattern in their F1 hybrids. Among the 24,721 polyadenylation sites (pAs) from 7,271 genes expressing multiple pAs, we identified 3,747 pAs showing significant divergence between the two strains. After integrating the allele-specific data from F1 hybrids, we demonstrated that these events could be predominately attributed to cis-regulatory effects. Further systematic sequence analysis of the regions in proximity to cis-divergent pAs revealed that the local RNA secondary structure and a poly(U) tract in the upstream region could negatively modulate the pAs usage. [ABSTRACT FROM AUTHOR]