1. Increased prevalences of head and neck cancers in patients with Sjögren's syndrome.
- Author
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Yang, Tzong‐Hann, Cheng, Yen‐Fu, Chen, Chin‐Shyan, and Lin, Herng‐Ching
- Subjects
SJOGREN'S syndrome ,HEAD & neck cancer ,CANCER patients ,CHI-squared test ,ODDS ratio - Abstract
Objective: This study aimed to investigate prevalences of head and neck cancers in patients with and those without Sjögren's syndrome using a population‐based dataset. Methods: We retrieved sampled patients from Taiwan's Longitudinal Health Insurance Database. This study included 38 930 patients with Sjögren's syndrome and 155 720 propensity‐score matched comparison patients without Sjögren's syndrome. Results: Chi‐squared tests revealed that there was a statistically significant difference in the prevalences of head and neck cancers between patients with Sjögren's syndrome and comparison patients (1.77% vs. 1.22%, p < 0.001). The odds ratio for head and neck cancers for patients with Sjögren's syndrome relative to the comparison group was 1.452 (95% CI = 1.325–1.592). Conclusions: Our study demonstrated that patients with Sjögren's syndrome face increased odds of head and neck cancers, encompassing several sites including the oral cavity, oropharynx, nasopharynx, and thyroid. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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