39 results on '"Lynnerup, Niels"'
Search Results
2. Leprosy in medieval Denmark: Exploring life histories through a multi‐tissue and multi‐isotopic approach.
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Brozou, Anastasia, Fuller, Benjamin T., Grimes, Vaughan, Lynnerup, Niels, Boldsen, Jesper L., Jørkov, Marie Louise, Pedersen, Dorthe Dangvard, Olsen, Jesper, and Mannino, Marcello A.
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STABLE isotopes ,HANSEN'S disease ,ANTHROPOLOGY ,ARCHAEOLOGY ,FACIAL bones - Abstract
Objectives: By focusing on two Danish leprosaria (Næstved and Odense; 13th–16th c. CE) and using diet and origin as proxies, we follow a multi‐isotopic approach to reconstruct life histories of patients and investigate how leprosy affected both institutionalized individuals and the medieval Danish community as a whole. Materials and Methods: We combine archaeology, historical sources, biological anthropology, isotopic analyses (δ13C, δ15N, δ34S, 87Sr/86Sr) and radiocarbon dating, and further analyze bones with different turnover rates (ribs and long bones). Results: The δ13C, δ15N and δ34S results indicate a C3 terrestrial diet with small contributions of marine protein for leprosy patients and individuals from other medieval Danish sites. A similar diet is seen through time, between males and females, and patients with and without changes on facial bones. The isotopic comparison between ribs and long bones reveals no significant dietary change. The δ34S and 87Sr/86Sr results suggest that patients were local to the regions of the leprosaria. Moreover, the radiocarbon dates show a mere 50% agreement with the arm position dating method used in Denmark. Conclusions: A local origin for the leprosy patients is in line with historical evidence, unlike the small dietary contribution of marine protein. Although only 10% of the analyzed individuals have rib/long bone offsets that undoubtedly show a dietary shift, the data appear to reveal a pattern for 25 individuals (out of 50), with elevated δ13C and/or δ15N values in the ribs compared to the long bones, which points toward a communal type of diet and reveals organizational aspects of the institution. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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3. Evaluating osteological ageing from digital data.
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Villa, Chiara, Buckberry, Jo, and Lynnerup, Niels
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HUMAN skeleton ,RIB cage ,COMPACT bone ,CANCELLOUS bone ,CRANIAL sutures ,DEAD ,ANTHROPOMETRY - Abstract
Age at death estimation of human skeletal remains is one of the key issues in constructing a biological profile both in forensic and archaeological contexts. The traditional adult osteological methods evaluate macroscopically the morphological changes that occur with increasing age of specific skeletal indicators, such as the cranial sutures, the pubic bone, the auricular surface of the ilium and the sternal end of the ribs. Technologies such as computed tomography and laser scanning are becoming more widely used in anthropology, and several new methods have been developed. This review focuses on how the osteological age‐related changes have been evaluated in digital data. First, the 3D virtual copies of the bones have been used to mimic the appearance of the dry bones and the application of the traditional methods. Secondly, the information directly extrapolated from CT scans has been used to assess qualitatively or quantitatively the changes of the trabecular bones, the thickness of the cortical bones, and to perform morphometric analyses. Lastly, the most innovative approach has been the mathematical quantification of the changes of the pelvic joints, calculating the complexity of the surface. The importance of new updated reference datasets, created thanks to the use of CT scanning in forensic settings, is also discussed. [ABSTRACT FROM AUTHOR]
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- 2019
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4. The Status of Forensic Anthropology in Europe and South Africa: Results of the 2016 FASE Questionnaire on Forensic Anthropology.
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Obertová, Zuzana, Adalian, Pascal, Baccino, Eric, Cunha, Eugenia, De Boer, Hans H., Fracasso, Tony, Kranioti, Elena, Lefévre, Philippe, Lynnerup, Niels, Petaros, Anja, Ross, Ann, Steyn, Maryna, and Cattaneo, Cristina
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FORENSIC anthropology ,GRADUATE education ,ANTHROPOLOGISTS ,QUESTIONNAIRES ,FORENSIC sciences ,SOUTH Africans - Abstract
One of the goals of the Forensic Anthropology Society of Europe (FASE) is to map the existing education and practice opportunities in the field of forensic anthropology in order to support the development of the discipline and to optimize the training courses provided by the Society. To address this goal, an online questionnaire was sent to European and South African practitioners of forensic anthropology and related disciplines in 2016. The results of the questionnaire showed that the status and roles of forensic anthropologists vary depending on the national legal systems, education, and employment status of the practitioners. Despite the fact that the expertise of forensic anthropologists has been increasingly requested in a variety of investigations and the spectrum of tasks has become broader, including identification of living persons, specialized education in forensic anthropology is still restricted to a few graduate and postgraduate programs in European countries and to annual FASE courses. [ABSTRACT FROM AUTHOR]
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- 2019
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5. Ancient pathogen DNA in human teeth and petrous bones.
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Margaryan, Ashot, Hansen, Henrik B., Rasmussen, Simon, Sikora, Martin, Moiseyev, Vyacheslav, Khoklov, Alexandr, Epimakhov, Andrey, Yepiskoposyan, Levon, Kriiska, Aivar, Varul, Liivi, Saag, Lehti, Lynnerup, Niels, Willerslev, Eske, and Allentoft, Morten E.
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HUMAN DNA ,FOSSIL DNA ,YERSINIA pestis ,TEETH ,SHOTGUN sequencing - Abstract
Recent ancient DNA (aDNA) studies of human pathogens have provided invaluable insights into their evolutionary history and prevalence in space and time. Most of these studies were based on DNA extracted from teeth or postcranial bones. In contrast, no pathogen DNA has been reported from the petrous bone which has become the most desired skeletal element in ancient DNA research due to its high endogenous DNA content. To compare the potential for pathogenic aDNA retrieval from teeth and petrous bones, we sampled these elements from five ancient skeletons, previously shown to be carrying Yersinia pestis. Based on shotgun sequencing data, four of these five plague victims showed clearly detectable levels of Y. pestis DNA in the teeth, whereas all the petrous bones failed to produce Y. pestis DNA above baseline levels. A broader comparative metagenomic analysis of teeth and petrous bones from 10 historical skeletons corroborated these results, showing a much higher microbial diversity in teeth than petrous bones, including pathogenic and oral microbial taxa. Our results imply that although petrous bones are highly valuable for ancient genomic analyses as an excellent source of endogenous DNA, the metagenomic potential of these dense skeletal elements is highly limited. This trade-off must be considered when designing the sampling strategy for an aDNA project. [ABSTRACT FROM AUTHOR]
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- 2018
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6. Body surface area determined by whole-body CT scanning: need for new formulae?
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Villa, Chiara, Primeau, Charlotte, Hesse, Ulrik, Hougen, Hans Petter, Lynnerup, Niels, and Hesse, Birger
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BODY surface area ,COMPUTED tomography ,STATURE ,BODY weight ,BODY mass index - Abstract
Calculation of the estimated body surface area ( BSA) by body height and weight has been a challenge in the past centuries due to lack of a well-documented gold standard. More recently, available techniques such as 3D laser surface scanning and CT scanning may be expected to quantify the BSA in an easier and more accurate way. This study provides the first comparison between BSA obtained from post-mortem whole-body CT scans and BSA calculated by nine predictive formulae. The sample consisted of 54 male cadavers ranging from 20 to 87 years old. 3D reconstructions were generated from CT scans using Mimics software, and BSA values were automatically extracted from the program. They were compared with nine predictive equations from the literature. Remarkably, close correlations ( r > 0·90) were found between BSA values from CT scans and those from the predictive formulae. A mean BSA of the 54 cadavers of 1·84-1·87 m
2 was calculated by all formulae except one, SD values varying between 0·171 and 0·223 m2 . T-tests revealed significant differences between mean BSA values calculated with CT and three of the formulae. Regression analyses showed intercepts >(0;0) and slopes <1·0 using all predictive equations, with the CT scan determination as gold standard. It is concluded that DuBois and DuBois' equation can be safely used in normal-weight male subjects with high accuracy, but it seems likely that BSA is underestimated in underweight subjects and overestimated in overweight individuals. Creation of new formulae specific for overweight subjects and children may be needed. [ABSTRACT FROM AUTHOR]- Published
- 2017
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7. Validation of the New Interpretation of Gerasimov's Nasal Projection Method for Forensic Facial Approximation Using CT Data.
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Maltais Lapointe, Genevieve, Lynnerup, Niels, and Hoppa, Robert D.
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FACE perception , *BIOMETRIC identification , *FORENSIC anthropology , *FORENSIC anthropology laboratories , *FORENSIC science equipment , *FORENSIC sciences - Abstract
The most common method to predict nasal projection for forensic facial approximation is Gerasimov's two-tangent method. Ullrich H, Stephan CN ( J Forensic Sci, 2011; 56: 470) argued that the method has not being properly implemented and a revised interpretation was proposed. The aim of this study was to compare the accuracy of both versions using a sample of 66 postmortem cranial CT data. The true nasal tip was defined using pronasale and nasal spine line, as it was not originally specified by Gerasimov. The original guidelines were found to be highly inaccurate with the position of the nasal tip being overestimated by c. 2 cm. Despite the revised interpretation consistently resulting in smaller distance from true nasal tip, the method was not statistically accurate ( p > 0.05) in positioning the tip of the nose (absolute distance >5 mm). These results support that Gerasimov's method was not properly performed, and Ullrich H, Stephan CN ( J Forensic Sci, 2011; 56: 470) interpretation should be used instead. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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8. A Method for Estimating Age of Medieval Sub-Adults From Infancy to Adulthood Based on Long Bone Length.
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Primeau, Charlotte, Friis, Laila, Sejrsen, Birgitte, and Lynnerup, Niels
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REGRESSION analysis ,RADIOGRAPHY ,RADIOLOGY ,SCIENTIFIC photography ,BRAIN - Abstract
Objectives: To develop a series of regression equations for estimating age from length of long bones for archaeological sub-adults when aging from dental development cannot be performed. Further, to compare derived ages when using these regression equations, and two other methods. Material and Methods: A total of 183 skeletal sub-adults from the Danish medieval period, were aged from radiographic images. Linear regression formulae were then produced for individual bones. Age was then estimated from the femur length using three different methods: equations developed in this study, data based on a modern population (Maresh: Human growth and development (1970) pp 155-200), and, lastly, based on archeological data with known ages (Rissech et al.: Forensic Sci Int 180 (2008) 1-9). As growth of long bones is known to be non-linear it was tested if the regression model could be improved by applying a quadratic model. Results: Comparison between estimated ages revealed that the modern data result in lower estimated ages when compared to the Danish regression equations. The estimated ages using the Danish regression equations and the regression equations developed by Rissech et al. (Forensic Sci Int 180 (2007) 1-9) were very similar, if not identical. This indicates that the growth between the two archaeological populations is not that dissimilar. Discussion: This would suggest that the regression equations developed in this study may potentially be applied to archaeological material outside Denmark as well as later than the medieval period, although this would require further testing. The quadratic equations are suggested to yield more accurate ages then using simply linear regression equations. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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9. The Thule Inuit Mummies From Greenland.
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Lynnerup, Niels
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- 2015
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10. Bog Bodies.
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Lynnerup, Niels
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- 2015
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11. Quantitative Analysis of the Morphological Changes of the Pubic Symphyseal Face and the Auricular Surface and Implications for Age at Death Estimation.
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Villa, Chiara, Buckberry, Jo, Cattaneo, Cristina, Frohlich, Bruno, and Lynnerup, Niels
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QUANTITATIVE research ,DEATH rate ,COMPUTED tomography ,PELVIC bones ,BONE physiology ,FORENSIC sciences - Abstract
Age estimation methods are often based on the age-related morphological changes of the auricular surface and the pubic bone. In this study, a mathematical approach to quantify these changes has been tested analyzing the curvature variation on 3D models from CT and laser scans. The sample consisted of the 24 Suchey-Brooks ( SB) pubic bone casts, 19 auricular surfaces from the Buckberry and Chamberlain ( BC) 'recording kit' and 98 pelvic bones from the Terry Collection (Smithsonian Institution). Strong and moderate correlations between phases and curvature were found in SB casts (ρ 0.60-0.93) and BC 'recording kit' (ρ 0.47-0.75), moderate and weak correlations in the Terry Collection bones (pubic bones: ρ 0.29-0.51, auricular surfaces: ρ 0.33-0.50) but associated with large individual variability and overlap of curvature values between adjacent decades. The new procedure, requiring no expert judgment from the operator, achieved similar correlations that can be found in the classic methods. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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12. Surface Curvature of Pelvic Joints from Three Laser Scanners: Separating Anatomy from Measurement Error.
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Villa, Chiara, Gaudio, Daniel, Cattaneo, Cristina, Buckberry, Jo, Wilson, Andrew S., and Lynnerup, Niels
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FORENSIC sciences ,FORENSIC anthropology ,PELVIC bones ,OPTICAL scanners ,PUBIC symphysis ,CURVATURE ,SURFACE area - Abstract
Recent studies have reported that quantifying symphyseal and auricular surface curvature changes on 3D models acquired by laser scanners has a potential for age estimation. However, no tests have been carried out to evaluate the repeatability of the results between different laser scanners. 3D models of the two pelvic joints were generated using three laser scanners (Custom, Faro, and Minolta). The surface curvature, the surface area, and the distance between co-registered meshes were investigated. Close results were found for surface areas (differences between 0.3% and 2.4%) and for distance deviations (average <20 μm, SD <200 μm). The curvature values were found to be systematically biased between different laser scanners, but still showing similar trends with increasing phases/scores. Applying a smoothing factor to the 3D models, it was possible to separate anatomy from the measurement error of each instrument, so that similar curvature values could be obtained ( p < 0.05) independent of the specific laser scanner. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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13. The Use of CT Scans in Estimating Age at Death by Examining the Extent of Ectocranial Suture Closure.
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Boyd, Kristen Leigh, Villa, Chiara, and Lynnerup, Niels
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FORENSIC sciences ,FORENSIC anthropology ,AGE determination of animals ,COMPUTED tomography ,CRANIAL sutures - Abstract
We examined the utility of CT scans in the evaluation of degree of ectocranial suture closure. Five cranial points (left and right midcoronal positions, left and right midlambdoidal positions, and the lambda) were evaluated in 231 CT scans using a three-point scoring system (open, partial closed, and closed). The slice increment and thickness varied between three groups of the scans. The results showed a good correlation between degree of suture closure and increasing age in each group. Young individuals (<40 years) and old individuals (>60 years) could be clearly distinguished from the middle-aged individuals. ANOVA test revealed no difference between two groups of scans and between left and right sides ( p > 0.05). Interobserver agreement was good, especially considering the score by sides. The results of this study create the base for developing a robust and simple method to estimate the age at death using CT scans. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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14. Influence of Velocity on Variability in Gait Kinematics: Implications for Recognition in Forensic Science.
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Yang, Sylvia X. M., Larsen, Peter K., Alkjær, Tine, Lynnerup, Niels, and Simonsen, Erik B.
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CLOSED-circuit television ,GAIT in humans ,VELOCITY ,CRIME ,FORENSIC sciences ,HUMAN fingerprints - Abstract
Closed circuit television ( CCTV) footage is often available from crime scenes and may be used to compare perpetrators with suspects. Usually, the footage comprises incomplete gait cycles at different velocities, making gait pattern identification from crimes difficult. This study investigated the concurrence of joint angles throughout a gait cycle at three different velocities (3.0, 4.5, 6.0 km/h). Six datasets at each velocity were collected from 16 men. A variability range VR throughout the gait cycle at each velocity for each joint angle for each person was calculated. The joint angles at each velocity were compared pairwise, and whenever this showed values within the VR of this velocity, the case was positive. By adding the positives throughout the gait cycle, phases with high and low concurrences were located; peak concurrence was observed at mid-stance phase. Striving for the same velocity for the suspect and perpetrator is recommended. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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15. Gait as evidence.
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Lynnerup, Niels and Larsen, Peter Kastmand
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This study examines what in Denmark may constitute evidence based on forensic anthropological gait analyses, in the sense of pointing to a match (or not) between a perpetrator and a suspect, based on video and photographic imagery. Gait and anthropometric measures can be used when direct facial comparison is not possible because of perpetrators masking their faces. The nature of judicial and natural scientific forms of evidence is discussed, and rulings dealing with the admissibility of video footage and forensic evidence in general are given. Technical issues of video materials are discussed, and the study also discusses how such evidence may be presented, both in written statements and in court. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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16. Variability and Similarity of Gait as Evaluated by Joint Angles: Implications for Forensic Gait Analysis.
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Yang, Sylvia X.M., Larsen, Peter K., Alkjær, Tine, Simonsen, Erik B., and Lynnerup, Niels
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GAIT disorders ,BIOMETRIC identification ,CLOSED-circuit television ,CRIMINAL investigation ,FORENSIC anthropology ,FORENSIC sciences ,DIAGNOSIS - Abstract
Closed-circuit television (CCTV) footage is used in criminal investigations to compare perpetrators with suspects. Usually, incomplete gait cycles are collected, making evidential gait analysis challenging. This study aimed to analyze the discriminatory power of joint angles throughout a gait cycle. Six sets from 12 men were collected. For each man, a variability range VR (mean ± 1 SD) of a specific joint angle at a specific time point (a gait cycle was 100 time points) was calculated. In turn, each individual was compared with the 11 others, and whenever 1 of these 11 had a value within this individual's VR, it counted as positive. By adding the positives throughout the gait cycle, we created simple bar graphs; tall bars indicated a small discriminatory power, short bars indicated a larger one. The highest discriminatory power was at time points 60-80 in the gait cycle. We show how our data can assess gait data from an actual case. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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17. Photogrammetric Documentation of Regions of Interest at Autopsy-A Pilot Study.
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Slot, Liselott, Larsen, Peter K., and Lynnerup, Niels
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PHOTOGRAMMETRY ,DOCUMENTATION ,AUTOPSY ,PHYSICAL measurements ,FORENSIC pathology ,HUMAN body - Abstract
In this pilot study, the authors tested whether photogrammetry can replace or supplement physical measurements made during autopsies and, based on such measurements, whether virtual computer models may be applicable in forensic reconstructions. Photogrammetric and physical measurements of markers denoting wounds on five volunteers were compared. Virtual models of the volunteers were made, and the precision of the markers' locations on the models was tested. Twelve of 13 mean differences between photogrammetric and physical measurements were below 1 cm, which indicates that the photogrammetric method has a high accuracy. The precision of the markers' location on the models was somewhat less, although the method is still promising and potentially superior to the current procedures used for reconstructions. The possibility to measure any distance on a body, even after the autopsy is concluded and the corpse is no longer available, is one of the biggest benefits of photogrammetry. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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18. Technical Note: Reliability of suchey-brooks and buckberry-chamberlain methods on 3D visualizations from CT and laser scans.
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Villa, Chiara, Buckberry, Jo, Cattaneo, Cristina, and Lynnerup, Niels
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TOMOGRAPHY ,PUBIC bone ,SURFACE texture ,VISUALIZATION ,MATHEMATICAL models ,PUBIC symphysis - Abstract
ABSTRACT Previous studies have reported that the ageing method of Suchey-Brooks (pubic bone) and some of the features applied by Lovejoy et al. and Buckberry-Chamberlain (auricular surface) can be confidently performed on 3D visualizations from CT-scans. In this study, seven observers applied the Suchey-Brooks and the Buckberry-Chamberlain methods on 3D visualizations based on CT-scans and, for the first time, on 3D visualizations from laser scans. We examined how the bone features can be evaluated on 3D visualizations and whether the different modalities (direct observations of bones, 3D visualization from CT-scan and from laser scans) are alike to different observers. We found the best inter-observer agreement for the bones versus 3D visualizations, with the highest values for the auricular surface. Between the 3D modalities, less variability was obtained for the 3D laser visualizations. Fair inter-observer agreement was obtained in the evaluation of the pubic bone in all modalities. In 3D visualizations of the auricular surfaces, transverse organization and apical changes could be evaluated, although with high inter-observer variability; micro-, macroporosity and surface texture were very difficult to score. In conclusion, these methods were developed for dry bones, where they perform best. The Suchey-Brooks method can be applied on 3D visualizations from CT or laser, but with less accuracy than on dry bone. The Buckberry-Chamberlain method should be modified before application on 3D visualizations. Future investigation should focus on a different approach and different features: 3D laser scans could be analyzed with mathematical approaches and sub-surface features should be explored on CT-scans. Am J Phys Anthropol 151:158-163, 2013. © 2013 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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19. The Lateral Angle Revisited: A Validation Study of the Reliability of the Lateral Angle Method for Sex Determination Using Computed Tomography ( CT),.
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Morgan, Jennifer, Lynnerup, Niels, and Hoppa, Robert D.
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SEX determination of human remains , *TEMPORAL bone , *COMPUTED tomography , *AUTOPSY , *FORENSIC anthropology - Abstract
This article presents the results of a validation study of a previously published method of sex determination from the temporal bone. The purpose of this study was to evaluate the lateral angle method for the internal acoustic canal for accurately determining the sex of human skeletal remains using measurements taken from computed tomography ( CT) scans. Previous reports have observed that the lateral angle size in females is significantly larger than in males. The method was applied to an independent series of 77 postmortem CT scans (42 males, 35 females) to validate its accuracy and reliability. The mean lateral angle of the internal acoustic canal was found to be larger in females (46.5°) than in males (43.4°). However, the difference was not statistically significant and the sex differences reported in previous studies were not substantiated. In light of the observed results, the lateral angle method appears to be of minimal practical use in forensic anthropology and archeology. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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20. The Lateral Angle Revisited: A Validation Study of the Reliability of the Lateral Angle Method for Sex Determination Using Computed Tomography ( CT),.
- Author
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Morgan, Jennifer, Lynnerup, Niels, and Hoppa, Robert D.
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SEX determination of human remains ,TEMPORAL bone ,COMPUTED tomography ,AUTOPSY ,FORENSIC anthropology - Abstract
This article presents the results of a validation study of a previously published method of sex determination from the temporal bone. The purpose of this study was to evaluate the lateral angle method for the internal acoustic canal for accurately determining the sex of human skeletal remains using measurements taken from computed tomography ( CT) scans. Previous reports have observed that the lateral angle size in females is significantly larger than in males. The method was applied to an independent series of 77 postmortem CT scans (42 males, 35 females) to validate its accuracy and reliability. The mean lateral angle of the internal acoustic canal was found to be larger in females (46.5°) than in males (43.4°). However, the difference was not statistically significant and the sex differences reported in previous studies were not substantiated. In light of the observed results, the lateral angle method appears to be of minimal practical use in forensic anthropology and archeology. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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21. Uniform Diet in a Diverse Society. Revealing New Dietary Evidence of the Danish Roman Iron Age Based on Stable Isotope Analysis.
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Jørkov, Marie Louise S., Jørgensen, Lars, and Lynnerup, Niels
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DIET ,IRON Age ,CARBON isotopes ,NITROGEN isotopes - Abstract
A systematic dietary investigation during Danish Roman Iron Age (1-375AD) is conducted by analyzing stable isotope ratios of carbon (δ
13 C) and nitrogen (δ15 N) in the collagen of human and animal bone. The human sample comprises 77 individuals from 10 burial sites. In addition 31 samples of mammals and fish were analyzed from same geographical area. The investigation characterizes the human diet among different social groupings and analyses dietary differences present between sex, age, and site phase groups. Diachronically, the study investigates the Roman influences that had an effect on social structure and subsistence economy in both the Early and Late Period. Geographically the locations are both inland and coastal. The isotopic data indicate extremely uniform diet both between and within population groups from Early and Late Roman periods and the data are consistent throughout the Roman Iron Age. Protein consumption was dominated by terrestrial animals with no differences among social status, age, sex, or time period, while terrestrial plant protein only seems to have contributed little in the diet. Furthermore, the consumption of marine or aquatic resources does not seem to have been important, even among the individuals living next to the coast. [ABSTRACT FROM AUTHOR]- Published
- 2010
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22. Technical Note: A Stereological Analysis of the Cross-Sectional Variability of the Femoral Osteon Population.
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Villa, Chiara and Lynnerup, Niels
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STEREOLOGY , *DEATH , *FEMUR , *CAUCASIAN race , *COMPUTER software - Abstract
Unbiased selection of regions of interest (ROIs) and unbiased definition of histological structures are needed to improve the repeatability of microscopic methods for age at death determination and to reduce operator subjectivity. We present results obtained by selecting ROIs according to stereological principles on a sample of 28 femoral cross sections of Caucasoid males aged 20-89 years. A regular grid was overlaid on the cross section, and the ROIs were selected as close as possible to the periosteum in the anterior, lateral, and medial regions. The areas consisting of all intact secondary osteons plus fragments were outlined and osteon population density, percent osteon population, area, and perimeter were calculated using stereological methods and software. Overall, the analyses of intra- and inter-section variability showed no significant difference between the ROIs, i.e., the location within the cross section of the ROIs does not affect the outcome of the analyses. The individual variability was found to be higher in adults aged 30-55 years than in other age ranges. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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23. Amino acid δ13C analysis of hair proteins and bone collagen using liquid chromatography/isotope ratio mass spectrometry: paleodietary implications from intra-individual comparisons.
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Raghavan, Maanasa, McCullagh, James S. O., Lynnerup, Niels, and Hedges, Robert E. M.
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- 2010
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24. The Petrous Bone—A New Sampling Site for Identifying Early Dietary Patterns in Stable Isotopic Studies.
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Jørkov, Marie Louise S., Heinemeier, Jan, and Lynnerup, Niels
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PETROUS bone ,ISOTOPES ,CARBON ,NITROGEN ,FEMUR ,SKELETON - Abstract
Intraskeletal variation in the composition of carbon (δ
13 C) and nitrogen (δ15 N) stable isotopes measured in collagen is tested from various human bones and dentine. Samples were taken from the femur, rib, and petrous part of the temporal bone from well-preserved skeletons of both adults (n = 34) and sub-adults (n = 24). Additional samples of dentine from the root of 1st molars were taken from 16 individuals. The skeletal material is from a medieval cemetery (AD 1200-1573) in Holbæk, Denmark. Our results indicate that the petrous bone has an isotopic signal that differs significantly from that of femur and rib within the single skeleton (P < 0.001 and P < 0.001, respectively), with only minor variation seen between femur and rib. On the other hand, there was no significant difference between the petrous bone and the 1st molar. The intraskeletal variation may reflect differences in turnover rate among skeletal elements. The inner periosteal layer of the petrous bone is formed in uterus and does not undergo any further remodelling after the age of 2 years, whereas the rib and femur have a continuous turnover rate of ~5 and 10-20 years, respectively. From the results of this study it is believed the petrous bone may be a new useful bone element and a supplement or a proxy for teeth in the analysis of early dietary patterns as it may reflect diet in fetal stages and early years of life. [ABSTRACT FROM AUTHOR]- Published
- 2009
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25. Variability of Bodily Measures of Normally Dressed People Using PhotoModeler® Pro 5.
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Larsen, Peter K., Hansen, Lone, Simonsen, Erik B., and Lynnerup, Niels
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FORENSIC sciences ,FORENSIC anthropology ,PHOTOGRAMMETRY ,BODY weight ,WEIGHTS & measures ,STATURE ,BODY size ,RANGE of motion of joints ,CRIMINALS ,TELEVISION in security systems - Abstract
Photogrammetry is used in forensic science to help identify perpetrators from crime scenes by way of surveillance video, but the reproducibility of manually locating hidden body-points such as the joints remains to be established. In this study, we quantified the inter- and intra-observer variability of bodily measures of clothed individuals in two different poses and examined whether body segment lengths could be used to distinguish between people of similar stature. Stature was reproduced within ±1.5 cm in both the intra- and inter-observer study. Segment lengths were best reproduced when flexion in the joints was present in the intra-observer study, but only the length of the trunk could be used to distinguish between people of similar height. The reproducibility between the two poses was low. Other measures than stature should be used with caution and with the perpetrator and suspect in the same pose. Consistent guidelines for locating body-points should be developed. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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26. Gait Analysis in Forensic Medicine.
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Larsen, Peter K., Simonsen, Erik B., and Lynnerup, Niels
- Subjects
TELEVISION in security systems ,SECURITY systems ,GAIT disorders ,BIOCHEMISTRY ,PARAMETERS (Statistics) ,SURVEILLANCE radar ,KNEE ,HEEL bone ,ELECTRONIC surveillance - Abstract
Recordings from video surveillance systems are used as evidence from crime scenes. It would be useful to perform comparisons between disguised perpetrators and suspects based on their gait. We applied functional anatomical and biomechanical knowledge to analyze the gait of perpetrators, as recorded on surveillance video. Using a structured checklist, which addresses the single body segments during gait, we were able to give a statement concerning the gait patterns. Characteristic parameters were, e.g., varus instability in the knee at heel strike, and larger lateral flexion of the spinal column to one side than the other. Based on these characteristic features, we are able to state with reasonable certainty whether the suspect could be the perpetrator, but it is not possible to identify the perpetrator positively. Nevertheless, we have been involved in several cases where the court has found that this type of gait analysis was a valuable tool. [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
- View/download PDF
27. mtDNA From Hair and Nail Clarifies the Genetic Relationship of the 15th Century Qilakitsoq lnuit Mummies.
- Author
-
Gilbert, M. Thomas P., Djurhuus, Durita, Melchior, Linea, Lynnerup, Niels, Worobey, Michael, Wilson, Andrew S., Andreasen, Claus, and Dissing, Jørgen
- Subjects
INUIT ,MUMMIES ,LINEAGE ,ANCESTORS ,QILAKITSOQ Site (Greenland) - Abstract
The 15th century Inuit mummies excavated at Qilakitsoq in Greenland in 1978 were exceptionally well preserved and represent the largest find of naturally mummified specimens from the Arctic. The estimated ages of the individuals, their distribution between two adjacent graves, the results of tissue typing, and incomplete STR results led researchers to conclude that the eight mummies formed two distinct family groups: A grandmother (115), two daughters (113, 114), and their two children (Ill, 112) in one grave, and two sisters (1116, 1118) and a daughter (1117) of one of them in the other. Using mtDNA from hair and nail, we have reanalyzed the mummies. The results allowed the unambiguous assignment of each of the mummies to one of three mtDNA haplogroups: A2b (1/5); A2a (112, 113, 1116, 1118); A2a-311 (I/i, 1/4, 11/7), excluded some of the previous relations, and pointed to new ones. 115 is not the grandmother! mother of the individuals in Grave I, and she is not maternally related to any of the seven other mummies; 1/3 and 1/4 are not sisters and 11/7 is neither the daughter of 11/6 nor of 11/8. However, I/i may be the child of either 1/4 or 11/7 and these two may be sisters. 1/2 may be the son of 1/3, who may be the daughter of either II! 6 or 11/8, and these two may be sisters. The observation of haplogroups A2a and A2b amongst the 550-year-old Inuit puts a lower limit on the age of the two lineages in Greenland. [ABSTRACT FROM AUTHOR]
- Published
- 2007
- Full Text
- View/download PDF
28. Mummies.
- Author
-
Lynnerup, Niels
- Subjects
- *
MUMMIES , *AUTOPSY , *ENDOSCOPY , *PALEOPATHOLOGY , *ARCHAEOLOGICAL human remains , *BOG bodies - Abstract
The article presents a study which explored mummification and gave a presentation of various key mummy finds. The different ways of natural mummification include dessication, freezing and bog bodies, among other others. While artificial indicates that mummification is the result of intentional human activity. Other topics discussed include a brief history of mummy studies, methods in mummy research that include mummy autopsy and endoscopy, and relationship between mummies and paleopathology.
- Published
- 2007
- Full Text
- View/download PDF
29. Comparison of Handmarks in Manual Strangulation: An Experimental Study.
- Author
-
Kristensen, Mie E., Lynnerup, Niels, and Sejrsen, Birgitte
- Subjects
- *
HUMAN fingerprints , *FORENSIC sciences , *FORENSIC anthropology , *AUTOEROTIC asphyxia , *LABORATORIES , *ANTHROPOMETRY - Abstract
A police case with a strangulated woman with fingermarks on the neck and two suspects identifying each other as the perpetrator set off a laboratory experiment. Twenty-one males participated in the study. Blue paint was applied to their fingers, after which they grasped a neck dummy and pressed hard as if strangulating someone. The imprint was removed from the dummy, and their hands were photographed. Five imprints were randomly chosen and superimposed on the hand photographs in blind trials. In no cases did we match an imprint to the correct hand. However, in four cases we matched the imprint with several hands, one of which was the correct one. This means we were able to exclude nonmatches in 4/5 cases. Overall, matching of hands and fingermarks is difficult and inconclusive. Objective criteria for matching are difficult to establish, and matching is probably best suited for cases with specific anatomical features. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
30. Lateral Angle: A Method for Sexing Using the Petrous Bone.
- Author
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Norén, Anna, Lynnerup, Niels, Czarnetzki, Alfred, and Graw, Matthias
- Subjects
- *
SEX determination of human remains , *PETROUS bone , *ANTHROPOMETRY , *HUMAN skeleton , *HUMAN anatomy , *MORPHOLOGY , *FORENSIC anthropology - Abstract
We report on the results of applying the so-called lateral angle method for sex determination on skeletal remains. The lateral angle denotes the angle of the internal auditory canal in relation to the medial surface of the petrous part of the temporal bone. The method involves making a small cast of the proximal part of the internal acoustic canal and determining the angle at which the canal opens up to the surface of the petrous bone. The method has the great advantage of utilizing one of the sturdiest bone elements of the human skeleton, and may thus be especially suited for analyses of very fragmented skeletal remains or cremated bones, where the petrous bone may still be readily recognizable. The method was tested using a forensic sample of 113 petrous bones with known sex. Intra- and interobserver testing was also performed. We found a statistically significant difference in angle size between males and females (mean angle size of males, 39.3°; mean angle size of females, 48.2°; P < 0.001). There was no bilateral difference in angle size. In blind trials, 83.2% of petrous bones were assigned to the correct sex. We also tested the lateral angle method against an archaeological skeletal sample. True sex was not known for this sample; instead, sexing had been carried out by assessing pelvic and cranial morphology in independent trials. We found a higher concordance between the lateral angle and "pelvic" sex than for lateral angle and "cranial" sex. Finally, we note that subadult sexing may also be possible with this method. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
31. MtDNA Analysis of Human Remains From an Early Danish Christian Cemetery.
- Author
-
Rudbeck, Lars, Gilbert, M. Thomas P., Willersiev, Eske, Hansen, Anders J., Lynnerup, Niels, Christensen, Tom, and Dissing, J&3x00F8;rgen
- Subjects
MITOCHONDRIAL DNA ,CHRISTIAN cemeteries ,DNA ,MITOCHONDRIA ,CEMETERIES ,ARCHAEOLOGICAL human remains ,SCANDINAVIANS - Abstract
One of Denmark's earliest Christian cemeteries is Kongemarken, dating to around AD 1000-1250. A feature of early Scandinavian Christian cemeteries is sex segregation, with females buried on the northern sides and males on the southern sides. However, such separation was never complete; in the few early Christian cemeteries excavated in Scandinavia, there were always a few males placed on the north side, and some females on the south side. At Kongemarken, several males with juxtaposed females were found on the north side of the cemetery. Thus, to evaluate possible kinship relationships, and more general questions of population affinity, we analyzed mitochondrial DNA extracted from nine individuals excavated in two different areas within the cemetery: one male and four females from Area 1, and one male and three females from Area 2. Using stringent laboratory protocols, each individual was unequivocally assigned to a mitochondrial haplogroup. A surprising amount of haplogroup diversity was observed (Area 1:1 U7 (male), 1 H, 1 I, 1 J, and 1 T2; Area 2:2 H, 1 I, and 1 T, with one H being male); even the three subjects of haplogroup H were of different subtypes. This indicates that no subjects within each area were maternally related. The observed haplogroup, U7, while common in India and in western Siberian tribes, was not previously observed among present-day ethnic Scandinavians, and haplogroup I is rare (2%) in Scandinavia. These observations suggest that the individuals living in the Roskilde region 1,000 years ago were not all members of a tightly knit local population and comprised individuals with genetic links with populations that were from much farther away. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
32. Person Identification by Gait Analysis and Photogrammetry.
- Author
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Lynnerup, Niels and Vedel, Jens
- Subjects
- *
COMPUTER software , *FORENSIC sciences , *CRIMINAL investigation , *FORENSIC anthropology , *IMAGE analysis , *IDENTIFICATION - Abstract
Presents a study on the use of gait analysis and photogrammetry in person identification. Analysis and comparison of surveillance images from a bank robbery with images of suspect; Comparison of images of the suspect with the perpetrator in order to note bodily features and proportions that might indicate concordance as well as incongruity; Use of the computer software Photomodeler Pro in the study.
- Published
- 2005
- Full Text
- View/download PDF
33. Brief Communication: Age and Fractal Dimensions of Human Sagittal and Coronal Sutures.
- Author
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Lynnerup, Niels and Jacobsen, Jens Christian Brings
- Subjects
- *
CRANIAL sutures , *AGE , *BONE fractures - Abstract
The fractal dimensions of human sagittal and coronal sutures were calculated on 31 complete skulls from the Terry Collection. The aim was to investigate whether the fractal dimension, relying on the whole sutural length, might yield a better description of age-related changes in sutural morphology, as opposed to other methods of quantification, which generally rely on more arbitrary scoring systems. However, the fractal dimension did not yield better age correlations than other previously described methods. At best, the results reflected the general observation that young adults below age 40 years display an age-related development, but that it is impossible to arrive at any precise age determinations for older adults. It seems that for some individuals, suture obliteration simply does not take place, even at an advanced age, whereas for others, suture obliteration progresses rapidly. Until a better understanding of sutural biology is reached, this will render cranial sutures only marginally useful in age determination. This does not mean, however, that investigations should not be made to elucidate more unbiased methods of sutural morphology quantification. [ABSTRACT FROM AUTHOR]
- Published
- 2003
- Full Text
- View/download PDF
34. Short Review: The Use of Conventional X-rays in Mummy Studies.
- Author
-
Lynnerup, Niels and Rühli, Frank
- Published
- 2015
- Full Text
- View/download PDF
35. Stereolithography: Potential applications in anthropological studies.
- Author
-
Hjalgrim, Hernrik and Lynnerup, Niels
- Subjects
- *
IMAGING systems in archaeology , *IMAGE processing - Abstract
Discusses the technique of CT-based three-dimensional imaging stereolithography and its use on an Egyptian mummy. Non-disturbance of superimpositions of juxtapositional structures; Reformation into three-dimensional reconstructions; Danish Technological Institute; Rapid prototyping; 3D CT advantages.
- Published
- 1995
- Full Text
- View/download PDF
36. Bone mineral content in medieval Greenland Norse.
- Author
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Lynnerup, Niels and von Wowern, Nina
- Published
- 1997
- Full Text
- View/download PDF
37. Non-invasive Archaeology of Skeletal Material by CT Scanning and Three-dimensional Reconstruction.
- Author
-
LYNNERUP, NIELS, HJALGRIM, HENRIK, NIELSEN, LENE RINDAL, GREGERSEN, HENRIK, and THUESEN, INGOLF
- Published
- 1997
- Full Text
- View/download PDF
38. Expression of vasopressin mRNA in the hypothalamus of individuals with a diagnosis of schizophrenia.
- Author
-
Busch, Johannes R., Jacobsen, Christina, Lynnerup, Niels, Banner, Jytte, and Møller, Morten
- Published
- 2019
- Full Text
- View/download PDF
39. mtDNA from hair and nail clarifies the genetic relationship of the 15th century Qilakitsoq Inuit mummies.
- Author
-
Gilbert MT, Djurhuus D, Melchior L, Lynnerup N, Worobey M, Wilson AS, Andreasen C, and Dissing J
- Subjects
- DNA, Mitochondrial genetics, Genetics, Population, Greenland, Haplotypes, History, 15th Century, Humans, Inuit genetics, Paleopathology, Polymerase Chain Reaction methods, DNA, Mitochondrial history, Hair chemistry, Inuit history, Mummies, Nails chemistry
- Abstract
The 15th century Inuit mummies excavated at Qilakitsoq in Greenland in 1978 were exceptionally well preserved and represent the largest find of naturally mummified specimens from the Arctic. The estimated ages of the individuals, their distribution between two adjacent graves, the results of tissue typing, and incomplete STR results led researchers to conclude that the eight mummies formed two distinct family groups: A grandmother (I/5), two daughters (I/3, I/4), and their two children (I/1, I/2) in one grave, and two sisters (II/6, II/8) and a daughter (II/7) of one of them in the other. Using mtDNA from hair and nail, we have reanalyzed the mummies. The results allowed the unambiguous assignment of each of the mummies to one of three mtDNA haplogroups: A2b (I/5); A2a (I/2, I/3, II/6, II/8); A2a-311 (I/1, I/4, II/7), excluded some of the previous relations, and pointed to new ones. I/5 is not the grandmother/mother of the individuals in Grave I, and she is not maternally related to any of the seven other mummies; I/3 and I/4 are not sisters and II/7 is neither the daughter of II/6 nor of II/8. However, I/1 may be the child of either I/4 or II/7 and these two may be sisters. I/2 may be the son of I/3, who may be the daughter of either II/6 or II/8, and these two may be sisters. The observation of haplogroups A2a and A2b amongst the 550-year-old Inuit puts a lower limit on the age of the two lineages in Greenland.
- Published
- 2007
- Full Text
- View/download PDF
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