7 results on '"Mandloi, Shreya"'
Search Results
2. Stellate ganglion block for treating post‐COVID‐19 parosmia.
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Naimi, Bita R., Garvey, Emily, Chandna, Megha, Duffy, Alexander, Hunter, Stephanie R., Mandloi, Shreya, Kahn, Chase, Farquhar, Douglas, D'Souza, Glen, Rabinowitz, Mindy, Rosen, Marc, Toskala, Elina, Roedl, Johannes B., Zoga, Adam, Nyquist, Gurston, and Rosen, David
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- 2024
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3. The role of the insula in chronic pain following spinal cord injury: A resting‐state fMRI study.
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Mandloi, Shreya, Syed, Mashaal, Shoraka, Omid, Ailes, Isaiah, Kang, Ki Chang, Sathe, Anish, Heller, Joshua, Thalheimer, Sara, Mohamed, Feroze B., Sharan, Ashwini, Harrop, James, Krisa, Laura, Matias, Caio, and Alizadeh, Mahdi
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SPINAL cord injuries , *CHRONIC pain , *INSULAR cortex , *AFFERENT pathways , *EFFERENT pathways - Abstract
Background and Purpose: Spinal cord injury (SCI) results in the loss of motor and sensory function from disconnections between efferent and afferent pathways. Most SCI patients are affected with chronic neuropathic pain, but there is a paucity of data concerning neuroplastic changes following SCI. Chronic pain disrupts default networks and is associated with abnormal insular connectivity. The posterior insula (PI) is associated with the degree of pain and intensity of pain. The anterior insula (AI) is related to signal changes. Comprehension of SCI pain mechanisms is essential to elucidate effective treatment options. Methods: This study examines the insular gyri functional connectivity (FC) of seven (five male, two female) SCI participants with moderate‐severe chronic pain compared to 10 (five male, five female) healthy controls (HC). All subjects had 3‐Tesla MRI performed and resting‐state functional MRI (fMRI) was acquired. FC metrics were obtained from the comparisons of resting‐state fMRI among our various groups. A seed‐to‐voxel analysis was pursued, encompassing six gyri of the insula. For multiple comparisons, a correction was applied with a significance level of p <.05. Results: There were significant differences in FC of the insula between SCI participants with chronic pain compared with HC. In the SCI participants, there was hyperconnectivity of the AI and PI to the frontal pole. In addition, there was increased FC noted between the PI and the anterior cingulate cortex. Hyperconnectivity was also observed between the AI and the occipital cortex. Conclusions: These findings illustrate that there is a complex hyperconnectivity and modulation of pain pathways after traumatic SCI. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Evaluation of eight registration algorithms applied to the insula and insular gyri.
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Kang, KiChang, Sathe, Anish, Mandloi, Shreya, Muller, Jennifer, Ozuna, Glenn Arturo Gonzalez, Franco, Daniel, Miller, Christopher, Sharan, Ashwini, Mohamed, Feroze B., Faro, Scott, Alizadeh, Mahdi, and Wu, Chengyuan
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HIPPOCAMPAL sclerosis ,INSULAR cortex ,TEMPORAL lobe epilepsy ,TWO-way analysis of variance ,RECORDING & registration ,GRAY matter (Nerve tissue) ,MULTIPLE comparisons (Statistics) - Abstract
Background and Purpose: Spatial registration is crucial in establishing correspondence between anatomic brain regions for research and clinical purposes. The insular cortex (IC) and gyri (IG) are implicated in various functions and pathologies including epilepsy. Optimizing registration of the insula to a common atlas can improve the accuracy of group‐level analyses. Here, we compared six nonlinear, one linear, and one semiautomated registration algorithms (RAs) for registering the IC and IG to the Montreal Neurologic Institute standard space (MNI152). Methods: 3T images acquired from 20 controls and 20 temporal lobe epilepsy patients with mesial temporal sclerosis underwent automated segmentation of the insula. This was followed by manual segmentation of the entire IC and six individual IGs. Consensus segmentations were created at 75% agreement for IC and IG before undergoing registration to MNI152 space with eight RAs. Dice similarity coefficients (DSCs) were calculated between segmentations after registration and the IC and IG in MNI152 space. Statistical analysis involved the Kruskal‐Wallace test with Dunn's test for IC and two‐way analysis of variance with Tukey's honest significant difference test for IG. Results: DSCs were significantly different between RAs. Based on multiple pairwise comparisons, we report that certain RAs performed better than others across population groups. Additionally, registration performance differed according to specific IG. Conclusion: We compared different methods for registering the IC and IG to MNI152 space. We found differences in performance between RAs, which suggests that algorithm choice is important factor in analyses involving the insula. [ABSTRACT FROM AUTHOR]
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- 2023
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5. CPAP‐induced sphenoid sinus pressures after endoscopic sinus surgery.
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D'Souza, Glen E., Duffy, Alexander, Mandloi, Shreya, Garvey, Emily, Naimi, Bita, Hannikainen, Paavali, Benedict, Peter, Nyquist, Gurston N., Farrell, Christopher, Rosen, Marc, Toskala, Elina, Evans, James, and Rabinowitz, Mindy R.
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CONTINUOUS positive airway pressure , *SKULL base , *SPHENOID sinus , *MINIMALLY invasive procedures , *SKULL surgery - Abstract
Key Points Positive pressure transmitted from continuous positive airway pressure (CPAP) to the sinuses and skull base in the early post‐operative period has not been studied in live subjects and controversy exists in when to restart this post‐operatively. This study found that approximately 32.76% and 13.52% of the delivered CPAP pressures reached the post‐surgical sphenoid sinus and the mid‐nasal cavity, respectively, suggesting that surgical factors such as tissue edema, nasal packing, blood, and nasal secretions may provide a protective effect. Positive pressure transmitted from continuous positive airway pressure (CPAP) to the sinuses and skull base in the early post‐operative period has not been studied in live subjects and controversy exists in when to restart this post‐operatively.This study found that approximately 32.76% and 13.52% of the delivered CPAP pressures reached the post‐surgical sphenoid sinus and the mid‐nasal cavity, respectively, suggesting that surgical factors such as tissue edema, nasal packing, blood, and nasal secretions may provide a protective effect. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Gender‐based linguistic differences in letters of recommendation for rhinology fellowship over time: A dual‐institutional follow‐up study using natural language processing and deep learning.
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Vasan, Vikram, Cheng, Christopher P., Edalati, Shaun, Mandloi, Shreya, Lerner, David K., Del Signore, Anthony, Schaberg, Madeleine, Govindaraj, Satish, Rabinowitz, Mindy, Nyquist, Gurston, and Iloreta, Alfred Marc
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NATURAL language processing , *DEEP learning , *NOSE , *SEX discrimination - Abstract
Key points This follow‐up dual‐institutional and longitudinal study further evaluated for underlying gender biases in LORs for rhinology fellowship. Explicit and implicit linguistic gender bias was found, heavily favoring male applicants [ABSTRACT FROM AUTHOR]
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- 2024
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7. Transoral Robotic Surgery Versus Hypoglossal Nerve Stimulation for OSA: A Cost Analysis Study.
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Mandloi S, Garg N, Naimi B, Shah R, Kaki P, Alnemri A, Duffy A, Zhan T, Kaffenberger TM, Boon MS, and Huntley CT
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Background: Transoral robotic surgery (TORS) lingual tonsillectomy and hypoglossal nerve stimulation (HGNS) are effective surgical interventions for well-selected patients with obstructive sleep apnea (OSA) intolerant to continuous positive airway pressure (CPAP) therapy. Previous publications have demonstrated that HGNS patients have a lower postoperative apnea-hypopnea index (AHI) and length of hospital stay than TORS patients. No prior study has investigated the differences in costs between HGNS and TORS., Objectives: This study aims to compare surgery-related costs in patients undergoing HGNS versus TORS lingual tonsillectomy for OSA intolerant to CPAP., Methods: A retrospective study on OSA patients intolerant to CPAP that underwent HGNS or TORS from 2015 to 2022 at a tertiary care center. Cost was defined as the dollar amount associated with providing a specific service prior to the application of insurance., Results: This study included 395 patients (375 UAS and 20 TORS). Average total cost was significantly higher in the UAS group than the TORS group (UAS: $25,582.60; TORS: $5832.60; p < 0.001). Operating room costs were also significantly higher in the UAS group (UAS: $1978.20; TORS: $1490.90; p = 0.001). The TORS cohort averaged higher costs for pharmacy (UAS: $201.30; TORS: $416.60; p < 0.001) and anesthesia (UAS: $139.00; TORS: $307.60; p < 0.001)., Discussion: The total cost was significantly higher in the UAS group compared to the TORS group. When making management decisions, it is important to consider the cost of care provided as well as patient-centered outcomes to optimize the value of care., Level of Evidence: N/A Laryngoscope, 2024., (© 2024 The Author(s). The Laryngoscope published by Wiley Periodicals LLC on behalf of The American Laryngological, Rhinological and Otological Society, Inc.)
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- 2024
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