Search

Your search keyword '"Martín Arroyo, Miguel"' showing total 1 results
Start Over Author "Martín Arroyo, Miguel" Publisher wiley-blackwell
1 results on '"Martín Arroyo, Miguel"'

1. Elucidating Noncovalent Reaction Mechanisms: G‐Quartet as an Intermediate in G‐Quadruplex Assembly.

Author

Martín‐Arroyo, Miguel, Prado, Anselmo, Chamorro, Raquel, Bilbao, Nerea, and González‐Rodríguez, David

Subjects
*ORGANIC solvents, *SUPRAMOLECULAR chemistry, *ANALOGY, *GUANINE, *EQUILIBRIUM
Abstract

In analogy to covalent reactions, the understanding of noncovalent association pathways is fundamental to influence and control any supramolecular process. Following an approach that is reminiscent of covalent methodologies, we study here, for the first time, the mechanism of G‐quadruplex formation in organic solvents. Our results support a reaction pathway in which the cation shifts the equilibrium towards a G‐quartet transient intermediate, which then acts as a template in the formation of the G‐quadruplex product. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results