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Your search keyword '"Mico, Maria Caterina"' showing total 1 results
Start Over Author "Mico, Maria Caterina" Publisher wiley-blackwell
1 results on '"Mico, Maria Caterina"'

1. Sequential allogeneic transplantation and ruxolitinib maintenance for a synchronous PCM1‐JAK2 positive myeloid sarcoma and acute B‐lymphoblastic leukemia.

Author

Rizzuto, Giuliana, Leoncin, Matteo, Imbergamo, Silvia, Taurino, Daniela, Mico, Maria Caterina, Tosi, Manuela, Michelato, Anna, Buklijas, Ksenija, Spinelli, Orietta, Lussana, Federico, Lessi, Federica, Pizzi, Marco, Bonaldi, Laura, Binotto, Gianni, Rambaldi, Alessandro, and Gurrieri, Carmela

Subjects
MYELOID sarcoma, ACUTE leukemia, RUXOLITINIB, MYELOPROLIFERATIVE neoplasms, CHIMERIC proteins
Abstract

The translocation t(8;9)(p22;p24) results in the production of a chimeric PCM1‐JAK2 fusion protein leading to the constitutive activation of the Janus Kinase 2 that renders this disease potentially sensitive to ruxolitinib. Here, we report an interesting case of PCM1‐JAK2 myeloproliferative neoplasm evolving in myeloid sarcoma and B precursor ALL. [ABSTRACT FROM AUTHOR]

Published
2022
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