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Encounters with, within and between digital technologies have become characteristic of life in the contemporary moment. This is, often, no different for displaced individuals seeking asylum across European states. Smartphones have become part of the everyday ‘doing’ of life for individuals governed through asylum systems which now includes routinely encountering the state. Whilst smartphones are commonly said to offer the promised affordances of increased connection or communication, this paper aims to explore how everyday encounters with the UK asylum state fall short of these imagined expectations. In its place, the paper identifies how a series of ongoing (non)encounters—encounters that fail to manifest in expected ways; characterised by pauses, delays or voids—become characteristic of the everyday experience of being a digitally connected asylum seeker in the UK. Drawing upon a year‐long ethnographic research project with people actively seeking asylum in the UK between 2022 and 2023, this paper thus explores how the increased uptake of smartphone affordances within the UK asylum system contributes to the ongoing administration of state slow violence: experienced as exhaustion through everyday digital (non)encounters. Developing the concept of the (non)encounter for geographic research, this paper outlines how forms of dis/connection become characteristic of the state encounter for asylum‐seeking individuals. These modes of dis/connection are traced as slow violence along the contours of neoliberalisation and hostile assemblages of asylum governance within the UK context. [ABSTRACT FROM AUTHOR]

Accessible summary: We talked to people who lived in a secure unit and their staff. We asked them about good relationships with each other. The majority of the people said that good relationships with staff can help people move back to the community and be "in a good space".Staff said that good relationships can stop people feeling angry. They said that they like to help people and have trust. It is important to have a good staff team who know the person well.Residents said staff help them and listen to them when they are upset. They said they like it when staff spend time with them doing activities.Based on what residents told us, we think it is important that services work on helping people to have good relationships. This is because these relationships were very important in helping people to move more quickly back into the community.Please see an easier to read version here: https://wp.me/pcRSAn‐3V Background: Despite repeated policy initiatives, an enduring number of people with learning disabilities remain resident in secure settings (also referred to as locked wards). The spatial and emotional distance from family and friends means that relationships with staff become central to people's lives, and are critical for a successful transition to making their home in the community. Methods: This article uses a synthesis of evidence from two qualitative studies. We re‐analysed data from fieldnotes and interview transcripts with people with learning disabilities resident in secure settings and with staff who worked with them. The purpose of the original studies was service improvement however, relationships —particularly with between staff and residents— emerged as a significant theme in both studies. Therefore, the data were revisited to explore these relationships in more depth. Findings: The analysis identified that positive relationships with staff were critical in enabling residents to be "in a good space"—something they and staff viewed as a crucial factor for moving on. The analysis identified four main themes: (i) the characteristics of positive relationships, (ii) the challenges for positive relationships, (iii) how positive relationships can be encouraged and (iv) how positive relationships support people to move on. Conclusion: We conclude that flattening the hierarchy between staff and residents is key when supporting people with learning disabilities to move on. We stress the importance of the "soft skills" in enabling people to transition back to their community. There is a pressing need for research with people who have made the transition from hospital to generate retrospective narratives about what elements of these relationships are most significant in supporting a successful transition. [ABSTRACT FROM AUTHOR]

Guillain-Barré syndrome following ChAdOx1-S/nCoV-19 vaccine. We read the two recent reports of Guillain-Barré syndrome (GBS) following SARS-CoV-2 vaccination with interest and were inspired to review GBS reports submitted to our enhanced spontaneous surveillance system in Victoria, Australia (SAEFVIC, Surveillance of Adverse Events Following Vaccination in the Community).1-3 Since 21 February 2021, Australia has administered both the AstraZeneca-Oxford (ChAdOx1-S) and Pfizer-BioNTech (BNT162b2) vaccines according to a risk-stratified rollout schedule, initially targeting higher risk groups including healthcare and border workers, as well as residents in aged care facilities (RACF). Guillain-Barré Syndrome in an Australian State Using Both mRNA and Adenovirus-Vector SARS-CoV-2 Vaccines. [Extracted from the article]

Herein we report the preparation of a series of Ru(II) complexes featuring α‐iminopyridine ligands bearing thioether functionality (NNSR, where R = Me, CH2Ph, Ph). Metallation using [(p‐cymene)RuCl]2 permits access to Ru complexes with a κ2‐N,N donor set in which the thioether moiety remains uncoordinated. In the presence of a strong field ligand such as acetonitrile or triphenylphosphine, the p‐cymene moiety is displaced, and the ligand adopts a κ3‐N,N,S binding mode. These complexes are characterized using a combination of solution and solid state methods, including the crystal structure of [(NNSMe)Ru (NCMe)2Cl]Cl. The κ2‐N,N‐Ru(II) complexes are shown to serve as efficient precatalysts for the oxidation of sec‐phenethyl alcohol at modest loadings (alcohol: Ru = 20:1), using a variety of external oxidants and solvents. The complex bearing an S‐Ph donor was found to be the most active oxidation catalyst of those surveyed, suggesting that the thioether donor plays an active role in the catalytic cycle. [ABSTRACT FROM AUTHOR]

Key points: A low protein diet had minimal effects on paternal cardiovascular function or renin–angiotensin system activity.Paternal low protein diet modified F1 neonatal and adult offspring renin–angiotensin system activity and cardiovascular function in a sperm and/or seminal plasma specific manner.Paternal low protein diet modified F1 male offspring testicular expression of central epigenetic regulators.Significant changes in F2 neonatal offspring growth and tissue angiotensin‐converting enzyme activity were programmed by paternal low protein diet in a sperm and/or seminal plasma specific manner. Although the impact of maternal diet on adult offspring health is well characterized, the role that a father's diet has on his offspring's health remains poorly defined. We establish the significance of a sup‐optimal paternal low protein diet for offspring vascular homeostasis and define the sperm and seminal plasma specific programming effects on cardiovascular health. Male C57BL6 mice were fed either a control normal protein diet (NPD; 18% protein) or an isocaloric low protein diet (LPD; 9% protein) for a minimum of 7 weeks. Using artificial insemination, in combination with vasectomized male mating, we generated offspring derived from either NPD or LPD sperm (devoid of seminal plasma) but in the presence of NPD or LPD seminal plasma (devoid of sperm). We observed that either LPD sperm or seminal fluid at conception impaired adult offspring vascular function in response to both vasoconstrictors and dilators. Underlying these changes in vascular function were significant changes in serum, lung and kidney angiotensin‐converting enzyme (ACE) activity, established in F1 offspring from 3 weeks of age, maintained into adulthood and present also within juvenile F2 offspring. Furthermore, we observed differential expression of multiple central renin–angiotensin system regulators in adult offspring kidneys. Finally, paternal diet modified the expression profiles of central epigenetic regulators of DNA methylation, histone modifications and RNA methylation in adult F1 male testes. These novel data reveal the impact of sub‐optimal paternal nutrition on offspring cardiovascular well‐being, programming offspring cardiovascular function through both sperm and seminal plasma specific mechanisms over successive generations. Key points: A low protein diet had minimal effects on paternal cardiovascular function or renin–angiotensin system activity.Paternal low protein diet modified F1 neonatal and adult offspring renin–angiotensin system activity and cardiovascular function in a sperm and/or seminal plasma specific manner.Paternal low protein diet modified F1 male offspring testicular expression of central epigenetic regulators.Significant changes in F2 neonatal offspring growth and tissue angiotensin‐converting enzyme activity were programmed by paternal low protein diet in a sperm and/or seminal plasma specific manner. [ABSTRACT FROM AUTHOR]

Background: The move to community support for all people with intellectual disabilities is an aspiration with international significance. In this article, we draw on rich accounts from women with intellectual disabilities detained under the Mental Health Act (E&W) 1983 and staff at an National Health Service secure setting in England to explore how "moving on" is defined and perceived. Methods: The study reports on an ethnographic study using the field‐notes and the 26 semi‐structured interviews with detained women and staff on three wards. Results: We first explore staff conceptions of moving on, which include behavioural change and utilizing coping strategies. Then, we discuss the areas of analysis that women discussed: taking back responsibility, success in arranged relationships, acceptance of regime and resistance to progression. Conclusion: The concepts of moving on were not determined by the women but by the service. We recommend further research which explores women's own rehabilitation requirements. [ABSTRACT FROM AUTHOR]

Pipelined Krylov methods seek to ameliorate the latency due to inner products necessary for projection by overlapping it with the computation associated with sparse matrix-vector multiplication. We clarify a folk theorem that this can only result in a speedup of 2× over the naive implementation. Examining many repeated runs, we show that stochastic noise also contributes to the latency, and we model this using an analytical probability distribution. Our analysis shows that speedups greater than 2× are possible with these algorithms. Copyright © 2016 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

With ongoing news of hardship and suffering in the United Kingdom and throughout the world, and in the context of austerity, shrinking public services and increasing social inequalities, it is sometimes difficult not to fall into despair, to feel hopeless or ineffectual. In this paper we consider counter‐practices to such despair and hopelessness that we hope will be helpful to all clinicians. [ABSTRACT FROM AUTHOR]