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A six-year-old boy presented with multiple skin-colored to erythematous nodules on the face and scalp since infancy. Excisional biopsy from the new lesion on the frontal scalp revealed a spindle cell lesion arranged in short fascicles and whorls in a chondromyxoid background (Figs. a,b). Whole-body diffusion MRI scan done at the time of presentation did not show any lesion at the previous site, but a small 2-cm lesion was noted in the glenoid region of the right scapular bone (Fig.). [Extracted from the article]

In this research program, chitosan film was prepared by blending chitosan with Cloisite 30 B at different concentrations 0 wt %, 1 wt %, and 2.5 wt %. The blends were characterized by Fourier transmission infrared spectroscopy (FTIR), scanning electron microscopy (SEM), X-ray diffraction (XRD) analysis. From the FTIR spectra the various groups present in chitosan/C 30 B blend were monitored. The homogeneity, morphology, and crystallinity of the blends were ascertained from SEM and XRD data, respectively. The most suitable form of blend was taken and used as a carrier for the controlled release of ofloxacin. The swelling studies have been carried out at different drug loading. Drug release kinetics was analyzed by plotting the cumulative release data versus time by fitting to an exponential equation which indicated the occurrence of non-Fickian type of kinetics. The drug release was investigated at different pH medium and it was found that the drug release depends upon the pH medium as well as the nature of matrix. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012 [ABSTRACT FROM AUTHOR]