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Fine-needle aspiration demonstrated clusters of spindle cells with mild anisonucleosis, elongated nuclei, small nucleoli and haemosiderin granules (Figure A,B). Microscopic examination showed a lymph node with a thin rim of lymphoid tissue (Figure A) and spindle cells arranged in solid sheets exhibiting ovoid to elongated nuclei, small nucleoli and nuclear inclusions. GLO:EW1/01sep19:his13859-fig-0001.jpg PHOTO (COLOR): A, Spindle cells cluster as well as isolated spindle cells (arrows). [Extracted from the article]

The article present a case study of a 70‐year‐old White man revealed biological cholestasis with an increased level of γ‐GT. It mentions abdominal tomography showed a mass in the left hepatic lobe, which is four centimetres in diameter and associated with a dilated left bile duct; and also mentions macroscopic examination displayed a four centimetres whitish mass invading the liver parenchyma and exhibiting intraductal growth.

The article presents a case study of a 50-year-old woman presented with previous contact with hepatitis B virus. The patient was diagnosed with typical characteristics of hepatocellular carcinoma at magnetic resonance imaging and contrast-enhanced computed tomography. The patient underwent segment 5 hepatectomy and histology showed a dense mononuclear infiltrate containing numerous plasma cells.

The article presents a case study of a 68-year-old male who presented to the hospital for follow-up of the resection of melanoma. It says that oncocytic lesion without any argument for melanoma metastasis was shown by the biopsy of the liver mass diagnosed in the patient. Moreover, biliary adenoma with oncocytic features was the final diagnosis to the patient.

Objectives: To evaluate the efficacy and safety of a 10‐day quadruple therapy containing colloidal bismuth sub‐citrate (CBS), esomeprazole (ESO), amoxicillin (AMO), and metronidazole (MET) for Helicobacter pylori (H. pylori) eradication in children. Methods: Monocentric, open‐label, prospective, single‐arm clinical trial in children aged 6–17 years with H. pylori infection. The study was carried out on consecutive patients with upper gastrointestinal symptoms and H. pylori infection confirmed by histology and culture of gastric biopsies. The outcome was evaluated using a 13C‐urea breath test 8–10 weeks post‐therapy. Adverse events and compliance were evaluated by daily journal and pill counting. Results: A total of 36 children fulfilling the inclusion criteria were enrolled. Eight (22.2%) of them had a prior H. pylori eradication treatment. Thirteen (36.1%) patients were infected by a strain resistant to MET and 8 (22.2%) by a strain resistant to both MET and Clarithromycin (CLA). In the intention‐to‐treat population (ITT), eradication was achieved in35/36patients (95%CI: 85%−99%). Twenty‐three children reported at least one adverse event (63.8%), mostly mild (nausea, vomiting, abdominal pain, diarrhea, dark stool, metallic taste, headache, and rash). The compliance rate was high, with 30 (83.3%) patients taking >90% of the treatment. Conclusion: 10‐day quadruple therapy containing CBS, ESO, AMO, and MET for H. pylori eradication in children is a safe and very effective solution, especially for previously treated patients and those infected with double resistant strains. [ABSTRACT FROM AUTHOR]

Keywords: papillary immature squamous metaplasia; anal canal EN papillary immature squamous metaplasia anal canal 886 887 2 10/18/21 20211101 NES 211101 Case summary A 63-year-old man presented with a condylomatous hemicirconferential exophytic lesion of the anal canal. Cervical dysplasia is another precancerous lesion mediated by HPV (nearly 100%), and also involves the maturation of a squamous mucosa. Papillary immature metaplasia of the anal canal: a low-grade lesion that can mimic a high-grade lesion. [Extracted from the article]

The article presents a case study of a 9-year-old girl with progressive dysphagia, thoracic pain and weight loss. Topics discussed include biopsy of the oesophageal mass revealing fibrous tissue with numerous plasmocytes; Barium swallow confirmed the circumferential narrowing of the oesophagus; and treatment of Immunoglobulin (IgG4)-related disease with corticosteroids and immunomodulators.