1. Exome analysis of treatment‐related AML after APL suggests secondary evolution.
- Author
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Wang, Tianjiao, Jacoby, Meagan A., Duncavage, Eric J., Miller, Christopher A., Heath, Sharon, Rahme, Ramy, Fenaux, Pierre, Ades, Lionel, Renneville, Aline, Cassinat, Bruno, Takeshita, Akihiro, Asou, Norio, Miyazaki, Yasushi, Kiyoi, Hitoshi, Ravandi, Farhad, Westervelt, Peter, Wartman, Lukas D., and Welch, John S.
- Subjects
ACUTE promyelocytic leukemia ,CANCER genetics ,REVERSE transcriptase polymerase chain reaction - Abstract
The article presents a case study of an older woman who initially presented with dysplasia and she developed acute promyelocytic leukaemia (APL) and was treated with all-trans retinoic acid and arsenic trioxide (ATRA/ATO). Information about treatment-related acute myeloid leukaemia (tAML) and treatment-related myelodysplastic syndrome is presented.
- Published
- 2019
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