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Background: It is unclear which cortical regions are specific to or commonly associated with the impairments of the upper/lower limbs and the activities of daily life (ADL) in stroke patients. Purpose: To investigate the relationships between MRI‐assessed surface‐based morphometry (SBM) features and motor function as well as ADL in participants with chronic stroke. Study Type: Prospective. Subjects: Thirty‐five participants with subcortical stroke more than 3 months from the first‐onset (age: 56.44 ± 9.56 years; 32 male). Field Strength/Sequence: T1‐weighted images, 3.0 T, three‐dimensional fast field‐echo sequence. Assessment: FreeSurfer (6.0) was used to parcellate each hemisphere into 34 regions based on the Desikan–Killiany atlas and to extract the surface area, volume, thickness, and curvature. The motor function and ADL were assessed by the Fugl‐Meyer Assessment for the Upper/Lower Extremity (FMA‐UE/FMA‐LE) and the Chinese version of the Modified Barthel Index (MBI‐C), respectively. Statistical Tests: A linear mixed‐effect model was applied to evaluate the relationship between the morphological features and the FMA‐UE, FMA‐LE, and MBI‐C. A false discovery rate corrected P value < 0.05 was considered statistically significant. Results: Correlations between the size of stroke lesion and MRI measurements did not pass the FDR correction (adjusted P > 0.05). SBM features in motor‐related and high‐order cognitive cortical regions showed significant correlations with FMA‐UE and FMA‐LE, respectively. Moreover, the thickness in the prefrontal cortex significantly positively correlated, while the surface area in the right supramarginal gyrus significantly negatively correlated, with both FMA‐UE, FMA‐LE, and MBI‐C. The thickness in the left frontal lobe significantly positively correlated with both FMA‐UE and MBI‐C. Data Conclusion: This study's findings suggest that different hemiparetic motor‐related outcomes in participants with subcortical stroke which suffered a corticospinal tract‐related injury show specific, but also share common, associations with several cortical regions. Evidence Level: 2 Technical Efficacy: Stage 2 [ABSTRACT FROM AUTHOR]

On‐site hydrogen peroxide production through electrocatalytic and photocatalytic oxygen reduction reactions has recently attracted broad research interest. However, practical applications have thus far been plagued by the low activity and the requirement of complex equipment. Here, inspired by the process of biological hydrogen peroxide synthesis catalyzed by enzymes, we report a Pt‐Au alloy to mimic the catalytic function of natural formate oxidase for hydrogen peroxide synthesis through aerobic oxidation of formic acid. The mass activity of the Pt‐Au alloy is three times higher than that of formate oxidase. Density functional theory calculations revealed that the efficient dehydrogenation of formic acid and the high selectivity of the subsequent reduction of oxygen to hydrogen peroxide account for the high hydrogen peroxide productivity. In addition, the formic acid aqueous solution provides an acidic environment, which is conducive to the utilization of the in situ generated hydrogen peroxide for oxidation reactions, including C−H bond oxidation and sterilization. [ABSTRACT FROM AUTHOR]