Search

Two new limonoids, kihadanin C (1) and 23-methoxydasylactone A (2), together with seven related known ones, 3 - 9, were isolated from the root bark of the plant Dictamnus dasycarpus. The structures of the new compounds were elucidated on the basis of extensive analyses of their spectroscopic data (1Dand 2D-NMR, MS) and by comparison of their NMR data with those reported in the literature. To the best of our knowledge, 1 presents the first example of A,D-seco limonoid with an unusual 3,4-dihydroxy- 2,5-dimethoxytetrahydrofuran moiety as ring E. In the bioassay in vitro, 7 showed moderate antibacterial activity against Staphylococcus aureus, while 8 and 9 displayed neuroprotective activities against H2O2-induced injury in SH-SY5Y cells. [ABSTRACT FROM AUTHOR]

Six new cembrane diterpenes, lobophytolides A–F (1–6, resp.), along with six known related cembranoids, 7–12, were isolated from the Hainan soft coral Lobophytumsp. Their structures, including their relative configuration, were elucidated by extensive analyses of the spectroscopic data and by comparison with related known compounds. [ABSTRACT FROM AUTHOR]

Three new thiophene-acetylenes, 7-chloroarctinone-b (1), rhapontiynethiophenes A (2) and B (3), along with arctinone-b (4) were isolated from the MeOH extract of the roots of Rhaponticum uniflorum (L.) DC. The structures of the new compounds were elucidated by detailed spectroscopic data analysis and by comparison with known compounds. [ABSTRACT FROM AUTHOR]

Four new highly oxygenated guaiane lactones, 1-epimenverin B (1), menverin F (2), 1-deoxymenverin F (3), and menverin G (4), together with the two known related analogues menverins B (5) and C (6), were isolated from the South China Sea gorgonian Menella sp. Their structures and relative configuration were elucidated by analysis of spectroscopic data and by comparison with those of known related compounds. [ABSTRACT FROM AUTHOR]

Two new ent-abietane diterpenoids, macrophynin E (1) and macrophynin F (2), and a known related ent-abietanoid (−)-lambertic acid (3), together with four known ent-kauranoids, were isolated from the roots and aerial parts of Isodon macrophylla, respectively. The structures of the new compounds were elucidated on the basis of spectroscopic-data analysis and chemical correlations. [ABSTRACT FROM AUTHOR]

Five new polycyclic Daphniphyllum alkaloids, macropodumines F (1) and G (2), 17-oxoyuzurimine (3), and macropodumines H (4) and I (5), were isolated from the leaves of D. macropodumMiq., collected in Sichuan Province, China. The structures and relative configurations of the new compounds – as well as of four known, related alkaloids – were elucidated on the basis of in-depth spectroscopic and mass-spectrometric analyses, by chemical derivatization, and by comparison of spectroscopic data with those of known compounds. [ABSTRACT FROM AUTHOR]

Two new uncommon nitrogenous sesquiterpenes, 11-ethoxy-3-formamidotheonellin (1) and 7-ethoxy-3-formamidobisabolane-8,10-diene (2), together with two known related sesquiterpenes, 3-formamidotheonellin (=theonellin formamide; 3) and theonellin isothiocyanate (4), were isolated from the Hainan sponge Axinyssa aff. variabilis. Their structures were determined on the basis of extensive spectroscopic analysis and by comparison of their NMR data with those of known compounds. [ABSTRACT FROM AUTHOR]

Four new neoclerodane diterpenoids, 15-epilupulin A (1), 6-O-deacetylajugamarin (2), and ajugadecumbenins A (3) and B (4), were isolated from the whole plants of Ajuga decumbens.Their structures were elucidated on the basis of spectroscopic data and chemical correlations. [ABSTRACT FROM AUTHOR]

The title compound, C29H44O6·CH4O, namely suberoreti­steroid A methanol solvate, is a fused hexa­cyclic steroid which was isolated from the South China Sea gorgonian Suberogorgia reticulata. There are two independent mol­ecules in the asymmetric unit. Suberoretisteroid A mol­ecules and methanol solvent mol­ecules are linked via inter­molecular O—H⋯O hydrogen bonds to form two independent two-dimensional frameworks. [ABSTRACT FROM AUTHOR]